Characterization of rat liver microsomal metabolites of clivorine, an hepatotoxic otonecine-type pyrrolizidine alkaloid

Drug Metabolism and Disposition

Volumn 28, Issue 12, 2000, Pages 1475-1483

  Lin, Ge ^a   Cui, Yan Yan ^a   Hawes, Edward M ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

7 GLUTATHIONYLDEHYDRORETRONECINE; 7,9 DIGLUTATHIONYLDEHYDRORETRONECINE; CLIVORIC ACID; CLIVORINE; DEHYDRORETRONECINE; DRUG METABOLITE; PYRROLIZIDINE ALKALOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DRUG CONJUGATION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG STRUCTURE; LIVER MICROSOME; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOTRANSFORMATION; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; MASS SPECTROMETRY; MICROSOMES, LIVER; PYRROLES; PYRROLIZIDINE ALKALOIDS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0033669269     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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