Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 1, 2002, Pages 225-231

  Hosoya, Ken Ichi ^a,b   Tomi, Masatoshi ^a,b   Ohtsuki, Sumio ^b,c   Takanaga, Hitomi ^b   Saeki, Shigeki ^c   Kanai, Yoshikatsu ^c   Endou, Hitoshi ^d   Naito, Mikihiko ^d   Tsuruo, Takashi ^e   Terasaki, Tetsuya ^b,c  

^a UNIVERSITY OF TOYAMA   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d KYORIN UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTINE; FREE RADICAL; GLUTAMIC ACID; GLUTATHIONE; LIPOPOLYSACCHARIDE; MALEIC ACID DIETHYL ESTER; MEMBRANE ANTIGEN; NITRIC OXIDE;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; CELL IMMORTALIZATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; GENE INDUCTION; GENETIC TRANSCRIPTION; MICHAELIS CONSTANT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALGORITHMS; AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CARRIER PROTEINS; CELLS, CULTURED; CYSTINE; GENE EXPRESSION REGULATION; GLUTAMIC ACID; GLUTATHIONE; KINETICS; MALE; MALEATES; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM; STIMULATION, CHEMICAL;

EID: 0036088957     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.302.1.225     Document Type: Article

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