메뉴 건너뛰기




Volumn 43, Issue 3, 2011, Pages 362-373

Pharmacokinetic properties of hemoglobin vesicles as a substitute for red blood cells

Author keywords

Accelerated blood clearance phenomenon; Artificial oxygen carrier; Disposition; Hemorrhagic shock; Hepatic chronic cirrhosis; Liposome; Mononuclear phagocyte system

Indexed keywords

ARTIFICIAL OXYGEN CARRIER; BLOOD SUBSTITUTE; FLUOROCARBON; HEMOGLOBIN; HEMOGLOBIN BASED OXYGEN CARRIER; MACROGOL; METHEMOGLOBIN; OXYGEN; PERFLUOROCARBON BASED OXYGEN CARRIER; UNCLASSIFIED DRUG;

EID: 79960738078     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602532.2011.558094     Document Type: Review
Times cited : (17)

References (67)
  • 3
    • 34447620611 scopus 로고    scopus 로고
    • Cerebral oxygen delivery by liposome-encapsulated hemoglobin: A positron-emission tomographic evaluation in a rat model of hemorrhagic shock
    • DOI 10.1152/japplphysiol.00136.2006
    • Awasthi, V., Yee, S. H., Jerabek, P., Goins, B., Phillips, W. T. (2007). Cerebral oxygen delivery by liposome-encapsulated hemoglobin: a positron-emission tomographic evaluation in a rat model of hemorrhagic shock. J Appl Physiol 103:28-38. (Pubitemid 47092274)
    • (2007) Journal of Applied Physiology , vol.103 , Issue.1 , pp. 28-38
    • Awasthi, V.1    Yee, S.-H.2    Jerabek, P.3    Goins, B.4    Phillips, W.T.5
  • 5
    • 0034861066 scopus 로고    scopus 로고
    • 14C-cholesterol labeled AmBisome to healthy volunteers
    • DOI 10.1177/00912700122010942
    • Bekersky, I., Fielding, R. M., Dressler, D. E., Kline, S., Buell, D. N., Walsh, T. J. (2001). Pharmacokinetics, excretion, and mass balance of 14C after administration of 14C-cholesterol-labeled AmBisome to healthy volunteers. J Clin Pharmacol 41:963-971. (Pubitemid 32786570)
    • (2001) Journal of Clinical Pharmacology , vol.41 , Issue.9 , pp. 963-971
    • Bekersky, I.1    Fielding, R.M.2    Dressler, D.E.3    Kline, S.4    Buell, D.N.5    Walsh, T.J.6
  • 7
    • 0042743959 scopus 로고    scopus 로고
    • Analysis of polyethylene-glycol-polylactide nano-dimension artificial red blood cells in maintaining systemic hemoglobin levels and prevention of methemoglobin formation
    • DOI 10.1081/BIO-120023155
    • Chang, T. M., Powanda, D., Yu, W. P. (2003). Analysis of polyethylene-glycol-polylactide nano-dimension artifcial red blood cells in maintaining systemic hemoglobin levels and prevention of methemoglobin formation. Artif Cells Blood Substit Immobil Biotechnol 31:231-247. (Pubitemid 36917864)
    • (2003) Artificial Cells, Blood Substitutes, and Immobilization Biotechnology , vol.31 , Issue.3 , pp. 231-247
    • Chang, T.M.S.1    Powanda, D.2    Yu, W.P.3
  • 8
    • 70349623928 scopus 로고    scopus 로고
    • A review of blood substitutes: Examining the history, clinical trial results, and ethics of hemoglobin-based oxygen carriers
    • Chen, J. Y., Scerbo, M., Kramer, G. (2009). A review of blood substitutes: examining the history, clinical trial results, and ethics of hemoglobin-based oxygen carriers. Clinics (Sao Paulo) 64:803-813.
    • (2009) Clinics (Sao Paulo) , vol.64 , pp. 803-813
    • Chen, J.Y.1    Scerbo, M.2    Kramer, G.3
  • 11
    • 0037681850 scopus 로고    scopus 로고
    • Pharmacokinetics of pegylated liposomal doxorubicin: Review of animal and human studies
    • DOI 10.2165/00003088-200342050-00002
    • Gabizon, A., Shmeeda, H., Barenholz, Y. (2003). Pharmacokinetics of pegylated liposomal doxorubicin: review of animal and human studies. Clin Pharmacokinet 42:419-436. (Pubitemid 36649037)
    • (2003) Clinical Pharmacokinetics , vol.42 , Issue.5 , pp. 419-436
    • Gabizon, A.1    Shmeeda, H.2    Barenholz, Y.3
  • 12
    • 0029348529 scopus 로고
    • Physiological responses, organ distribution, and circulation kinetics in anesthetized rats after hypovolemic exchange transfusion with technetium-99m-labeled liposome-encapsulated hemoglobin
    • Goins, B., Klipper, R., Sanders, J., Clif, R. O., Rudolph, A. S., Phillips, W. T. (1995). Physiological responses, organ distribution, and circulation kinetics in anesthetized rats after hypovolemic exchange transfusion with technetium-99m-labeled liposome-encapsulated hemoglobin. Shock 4:121-130.
    • (1995) Shock , vol.4 , pp. 121-130
    • Goins, B.1    Klipper, R.2    Sanders, J.3    Clif, R.O.4    Rudolph, A.S.5    Phillips, W.T.6
  • 13
    • 47949102936 scopus 로고    scopus 로고
    • Does hyperlipidemia injure the kidney?
    • Grone, E. F. , Grone, H. J. (2008). Does hyperlipidemia injure the kidney? Nat Clin Pract Nephrol 4:424-425.
    • (2008) Nat Clin Pract Nephrol , vol.4 , pp. 424-425
    • Grone, E.F.1    Grone, H.J.2
  • 14
    • 0029411044 scopus 로고
    • Hematologic efects of a novel hemoglobin-based oxygen carrier in normal male and female subjects
    • Hughes, G. S., Jr., Francome, S. F. , Antal, E. J., Adams, W. J., Locker, P. K., Yancey, E. P., et al. (1995). Hematologic efects of a novel hemoglobin-based oxygen carrier in normal male and female subjects. J Lab Clin Med 126:444-451.
    • (1995) J Lab Clin Med , vol.126 , pp. 444-451
    • Hughes Jr., G.S.1    Francome, S.F.2    Antal, E.J.3    Adams, W.J.4    Locker, P.K.5    Yancey, E.P.6
  • 15
    • 33750324646 scopus 로고    scopus 로고
    • Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes
    • DOI 10.1016/j.jconrel.2006.08.001, PII S0168365906003804
    • Ishida, T., Ichihara, M., Wang, X., Kiwada, H. (2006a). Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes. J Contr Rel 115:243-250. (Pubitemid 44634842)
    • (2006) Journal of Controlled Release , vol.115 , Issue.3 , pp. 243-250
    • Ishida, T.1    Ichihara, M.2    Wang, X.3    Kiwada, H.4
  • 16
    • 33645815708 scopus 로고    scopus 로고
    • Injection of PEGylated liposomes in rats elicits PEG-specifc IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes
    • Ishida, T., Ichihara, M., Wang, X., Yamamoto, K., Kimura, J., Majima, E., et al. (2006b). Injection of PEGylated liposomes in rats elicits PEG-specifc IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes. J Contr Rel 112:15-25.
    • (2006) J Contr Rel , vol.112 , pp. 15-25
    • Ishida, T.1    Ichihara, M.2    Wang, X.3    Yamamoto, K.4    Kimura, J.5    Majima, E.6
  • 17
    • 38749096618 scopus 로고    scopus 로고
    • Te contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats
    • Ishida, T., Kashima, S., Kiwada, H. (2008). Te contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats. J Contr Rel 126:162-165.
    • (2008) J Contr Rel , vol.126 , pp. 162-165
    • Ishida, T.1    Kashima, S.2    Kiwada, H.3
  • 18
    • 0037436030 scopus 로고    scopus 로고
    • Accelerated clearance of PEGylated liposomes in rats after repeated injections
    • DOI 10.1016/S0168-3659(02)00462-5
    • Ishida, T., Maeda, R., Ichihara, M., Irimura, K., Kiwada, H. (2003a). Accelerated clearance of PEGylated liposomes in rats after repeated injections. J Contr Rel 88:35-42. (Pubitemid 36173950)
    • (2003) Journal of Controlled Release , vol.88 , Issue.1 , pp. 35-42
    • Ishida, T.1    Maeda, R.2    Ichihara, M.3    Irimura, K.4    Kiwada, H.5
  • 20
    • 0030438721 scopus 로고    scopus 로고
    • Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, with an animal scale-up approach
    • Izumi, T., Enomoto, S., Hosiyama, K., Sasahara, K., Shibukawa, A., Nakagawa, T., et al. (1996). Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, with an animal scale-up approach. J Pharmacol Exp Ter 277:1630-1641. (Pubitemid 27167181)
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.277 , Issue.3 , pp. 1630-1641
    • Izumi, T.1    Enomoto, S.2    Hosiyama, K.3    Sasahara, K.4    Shibukawa, A.5    Nakagawa, T.6    Sugiyama, Y.7
  • 21
    • 52949142206 scopus 로고    scopus 로고
    • HBOC-201, hemoglobin glutamer-250 (bovine), Hemopure (Biopure Corporation
    • Jahr, J. S., Moallempour, M., Lim, J. C. (2008). HBOC-201, hemoglobin glutamer-250 (bovine), Hemopure (Biopure Corporation). Exp Opin Biol Ter 8:1425-1433.
    • (2008) Exp Opin Biol ter , vol.8 , pp. 1425-1433
    • Jahr, J.S.1    Moallempour, M.2    Lim, J.C.3
  • 22
    • 34447325354 scopus 로고    scopus 로고
    • Blood substitutes as pharmacotherapies in clinical practice
    • DOI 10.1097/ACO.0b013e328172225a, PII 0000150320070800000009
    • Jahr, J. S., Walker, V. , Manoochehri, K. (2007). Blood substitutes as pharmacotherapies in clinical practice. Curr Opin Anaesthesiol 20:325-330. (Pubitemid 47051893)
    • (2007) Current Opinion in Anaesthesiology , vol.20 , Issue.4 , pp. 325-330
    • Jahr, J.S.1    Walker, V.2    Manoochehri, K.3
  • 24
    • 0032496676 scopus 로고    scopus 로고
    • Identification of proteins mediating clearance of liposomes using a liver perfusion system
    • DOI 10.1016/S0169-409X(97)00132-4, PII S0169409X97001324
    • Kiwada, H., Matsuo, H., Harashima, H. (1998). Identifcation of proteins mediating clearance of liposomes using a liver perfusion system. Adv Drug Deliv Rev 32:61-79. (Pubitemid 28277176)
    • (1998) Advanced Drug Delivery Reviews , vol.32 , Issue.1-2 , pp. 61-79
    • Harashima, H.1    Matsuo, H.2    Kiwada, H.3
  • 26
    • 0023054482 scopus 로고
    • Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: Preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids
    • Kuipers, F., Spanjer, H. H., Havinga, R., Scherphof, G. L., Vonk, R. J. (1986). Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids. Biochim Biophys Acta 876:559-566.
    • (1986) Biochim Biophys Acta , vol.876 , pp. 559-566
    • Kuipers, F.1    Spanjer, H.H.2    Havinga, R.3    Scherphof, G.L.4    Vonk, R.J.5
  • 28
    • 0035912180 scopus 로고    scopus 로고
    • Blood product from cattle wins approval for use in humans
    • Lok, C. (2001). Blood product from cattle wins approval for use in humans. Nature 410:855. (Pubitemid 32335805)
    • (2001) Nature , vol.410 , Issue.6831 , pp. 855
    • Lok, C.1
  • 29
    • 44249093233 scopus 로고    scopus 로고
    • Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: A meta-analysis
    • DOI 10.1001/jama.299.19.jrv80007
    • Natanson, C., Kern, S. J., Lurie, P., Banks, S. M., Wolfe, S. M. (2008). Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis. JAMA 299:2304-2312. (Pubitemid 351724397)
    • (2008) JAMA - Journal of the American Medical Association , vol.299 , Issue.19 , pp. 2304-2312
    • Natanson, C.1    Kern, S.J.2    Lurie, P.3    Banks, S.M.4    Wolfe, S.M.5
  • 30
    • 33645049055 scopus 로고    scopus 로고
    • Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: Pharmacology and efcacy
    • Noble, C. O., Krauze, M. T., Drummond, D. C., Yamashita, Y., Saito, R., Berger, M. S., et al. (2006). Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efcacy. Cancer Res 66:2801-2806.
    • (2006) Cancer Res , vol.66 , pp. 2801-2806
    • Noble, C.O.1    Krauze, M.T.2    Drummond, D.C.3    Yamashita, Y.4    Saito, R.5    Berger, M.S.6
  • 31
    • 4344650502 scopus 로고    scopus 로고
    • Is there a role for blood substitutes in civilian medicine: A drug for emergency shock cases?
    • DOI 10.1111/j.1525-1594.2004.07393.x
    • Nose, Y. (2004). Is there a role for blood substitutes in civilian medicine: a drug for emergency shock cases? Artif Org 28:807-812. (Pubitemid 39159153)
    • (2004) Artificial Organs , vol.28 , Issue.9 , pp. 807-812
    • Nose, Y.1
  • 32
    • 59849127731 scopus 로고    scopus 로고
    • Development of fbrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute
    • Okamura, Y, Takeoka, S, Eto, K, Maekawa, I, Fujie, T, Maruyama, H, et al. (2009). Development of fbrinogen gamma-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute. J Tromb Haemost 7:470-477.
    • (2009) J Tromb Haemost , vol.7 , pp. 470-477
    • Okamura, Y.1    Takeoka, S.2    Eto, K.3    Maekawa, I.4    Fujie, T.5    Maruyama, H.6
  • 33
    • 34250725014 scopus 로고    scopus 로고
    • 4-induced liver dysfunction in rat
    • DOI 10.1016/j.bcp.2007.04.025, PII S0006295207002845
    • Okumura, H., Katoh, M., Minami, K., Nakajima, M., Yokoi, T. (2007). Change of drug excretory pathway by CCl4-induced liver dysfunction in rat. Biochem Pharmacol 74:488-495. (Pubitemid 46963235)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.3 , pp. 488-495
    • Okumura, H.1    Katoh, M.2    Minami, K.3    Nakajima, M.4    Yokoi, T.5
  • 34
    • 34249995380 scopus 로고    scopus 로고
    • Alternatives to allogeneic blood transfusions
    • DOI 10.1016/j.bpa.2007.02.004, PII S1521689607000201, Blood Transfusion
    • Pape, A., Habler, O. (2007). Alternatives to allogeneic blood transfusions. Best Pract Res Clin Anaesthesiol 21:221-239. (Pubitemid 46888189)
    • (2007) Best Practice and Research in Clinical Anaesthesiology , vol.21 , Issue.2 , pp. 221-239
    • Pape, A.1    Habler, O.2
  • 37
    • 0034849666 scopus 로고    scopus 로고
    • Hemoglobin-vesicles as oxygen carriers: Influence on phagocytic activity and histopathological changes in reticuloendothelial system
    • Sakai, H., Horinouchi, H., Tomiyama, K., Ikeda, E., Takeoka, S., Kobayashi, K., et al. (2001) Hemoglobin-vesicles as oxygen carriers: infuence on phagocytic activity and histopathological changes in reticuloendothelial system. Am J Pathol 159:1079-1088. (Pubitemid 32847198)
    • (2001) American Journal of Pathology , vol.159 , Issue.3 , pp. 1079-1088
    • Sakai, H.1    Horinouchi, H.2    Tomiyama, K.3    Ikeda, E.4    Takeoka, S.5    Kobayashi, K.6    Tsuchida, E.7
  • 39
    • 1242320011 scopus 로고    scopus 로고
    • Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats
    • DOI 10.1097/01.CCM.0000109774.99665.22
    • Sakai, H., Masada, Y., Horinouchi, H., Yamamoto, M., Ikeda, E., Takeoka, S., et al. (2004b). Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats. Crit Care Med 32:539-545. (Pubitemid 38234138)
    • (2004) Critical Care Medicine , vol.32 , Issue.2 , pp. 539-545
    • Sakai, H.1    Masada, Y.2    Horinouchi, H.3    Yamamoto, M.4    Ikeda, E.5    Takeoka, S.6    Kobayashi, K.7    Tsuchida, E.8
  • 40
    • 59649097898 scopus 로고    scopus 로고
    • Fluid resuscitation with artifcial oxygen carriers in hemorrhaged rats: Profles of hemoglobin-vesicle degradation and hematopoiesis for 14 days
    • Sakai, H., Seishi, Y., Obata, Y., Takeoka, S., Horinouichi, H., Tsuchida, E., et al. (2009). Fluid resuscitation with artifcial oxygen carriers in hemorrhaged rats: profles of hemoglobin-vesicle degradation and hematopoiesis for 14 days. Shock 31:192-200.
    • (2009) Shock , vol.31 , pp. 192-200
    • Sakai, H.1    Seishi, Y.2    Obata, Y.3    Takeoka, S.4    Horinouichi, H.5    Tsuchida, E.6
  • 41
    • 36949017465 scopus 로고    scopus 로고
    • Haemoglobin-vesicles as artificial oxygen carriers: Present situation and future visions
    • DOI 10.1111/j.1365-2796.2007.01893.x
    • Sakai, H., Sou, K., Horinouchi, H., Kobayashi, K., Tsuchida, E. (2008). Haemoglobin-vesicles as artifcial oxygen carriers: present situation and future visions. J Intern Med 263:4-15. (Pubitemid 350243556)
    • (2008) Journal of Internal Medicine , vol.263 , Issue.1 , pp. 4-15
    • Sakai, H.1    Sou, K.2    Horinouchi, H.3    Kobayashi, K.4    Tsuchida, E.5
  • 43
    • 0034090354 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state
    • DOI 10.1021/bc990173h
    • Sakai, H., Tomiyama, K. I., Sou, K., Takeoka, S., Tsuchida, E. (2000). Poly(ethylene glycol)-conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state. Bioconjug Chem 11:425-432. (Pubitemid 30324910)
    • (2000) Bioconjugate Chemistry , vol.11 , Issue.3 , pp. 425-432
    • Sakai, H.1    Tomiyama, K.-I.2    Sou, K.3    Takeoka, S.4    Tsuchida, E.5
  • 44
    • 36248968719 scopus 로고    scopus 로고
    • Hemoglobin-vesicles for a transfusion alternative and targeted oxygen delivery
    • DOI 10.1080/08982100701529904, PII 785399706
    • Sakai, H., Tsuchida, E. (2007). Hemoglobin-vesicles for a transfusion alternative and targeted oxygen delivery. J Liposome Res 17:227-235. (Pubitemid 350133590)
    • (2007) Journal of Liposome Research , vol.17 , Issue.3-4 , pp. 227-235
    • Sakai, H.1    Tsuchida, E.2
  • 46
    • 0021257844 scopus 로고
    • Polymerized pyridoxylated hemoglobin: A red cell substitute with normal oxygen capacity
    • Sehgal, L. R., Gould, S. A., Rosen, A. L., Sehgal, H. L., Moss, G. S. (1984). Polymerized pyridoxylated hemoglobin: a red cell substitute with normal oxygen capacity. Surgery 95:433-438. (Pubitemid 14133924)
    • (1984) Surgery , vol.95 , Issue.4 , pp. 433-438
    • Sehgal, L.R.1    Gould, S.A.2    Rosen, A.L.3
  • 47
    • 34249915064 scopus 로고    scopus 로고
    • An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure
    • DOI 10.1007/s11095-007-9248-x
    • Shimoishi, K., Anraku, M., Kitamura, K., Tasaki, Y., Taguchi, K., Hashimoto, M., et al. (2007). An oral adsorbent, AST-120, protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure. Pharm Res 24:1283-1289. (Pubitemid 46870593)
    • (2007) Pharmaceutical Research , vol.24 , Issue.7 , pp. 1283-1289
    • Shimoishi, K.1    Anraku, M.2    Kitamura, K.3    Tasaki, Y.4    Taguchi, K.5    Hashimoto, M.6    Fukunaga, E.7    Maruyama, T.8    Otagiri, M.9
  • 48
    • 50249150337 scopus 로고    scopus 로고
    • Hemospan: A hemoglobin-based oxygen carrier for potential use as a blood substitute and for the potential treatment of critical limb ischemia
    • Smani, Y. (2008). Hemospan: a hemoglobin-based oxygen carrier for potential use as a blood substitute and for the potential treatment of critical limb ischemia. Curr Opin Investig Drugs 9:1009-1019.
    • (2008) Curr Opin Investig Drugs , vol.9 , pp. 1009-1019
    • Smani, Y.1
  • 49
    • 0034117689 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-modification of the phospholipid vesicles by using the spontaneous incorporation of poly(ethylene glycol)-lipid into the vesicles
    • DOI 10.1021/bc990135y
    • Sou, K., Endo, T., Takeoka, S., Tsuchida, E. (2000). Poly(ethylene glycol)-modifcation of the phospholipid vesicles by using the spontaneous incorporation of poly(ethylene glycol)-lipid into the vesicles. Bioconjug Chem 11:372-379. (Pubitemid 30324903)
    • (2000) Bioconjugate Chemistry , vol.11 , Issue.3 , pp. 372-379
    • Sou, K.1    Endo, T.2    Takeoka, S.3    Tsuchida, E.4
  • 50
    • 33847628429 scopus 로고    scopus 로고
    • Selective uptake of surface-modified phospholipid vesicles by bone marrow macrophages in vivo
    • DOI 10.1016/j.biomaterials.2007.01.041, PII S0142961207001275
    • Sou, K., Goins, B., Takeoka, S., Tsuchida, E., Phillips, W. T. (2007). Selective uptake of surface-modifed phospholipid vesicles by bone marrow macrophages in vivo. Biomaterials 28:2655-2666. (Pubitemid 46367213)
    • (2007) Biomaterials , vol.28 , Issue.16 , pp. 2655-2666
    • Sou, K.1    Goins, B.2    Takeoka, S.3    Tsuchida, E.4    Phillips, W.T.5
  • 52
    • 0042035626 scopus 로고    scopus 로고
    • The place of artificial oxygen carriers in reducing allogeneic blood transfusions and augmenting tissue oxygenation
    • Spahn, D. R., Kocian, R. (2003). Te place of artifcial oxygen carriers in reducing allogeneic blood transfusions and augmenting tissue oxygenation. Can J Anaesth 50:S41-S47 (Pubitemid 37038498)
    • (2003) Canadian Journal of Anesthesia , vol.50 , Issue.6 SUPPL.
    • Spahn, D.R.1    Kocian, R.2
  • 53
    • 29144443581 scopus 로고    scopus 로고
    • What happened to blood substitutes?
    • DOI 10.1016/j.tracli.2005.10.002, PII S1246782005001783
    • Stowell, C. P. (2005). What happened to blood substitutes? Transfus Clin Biol 12:374-379. (Pubitemid 41802973)
    • (2005) Transfusion Clinique et Biologique , vol.12 , Issue.5 , pp. 374-379
    • Stowell, C.P.1
  • 54
    • 79951927974 scopus 로고    scopus 로고
    • Repeated injection of high doses of hemoglobin encapsulated liposomes (hemoglobin-vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model
    • Taguchi, K., Iwao, Y., Watanabe, H., Kadowaki, D., Sakai, H., Kobayashi, K., et al. (2011a). Repeated injection of high doses of hemoglobin encapsulated liposomes (hemoglobin-vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model. Drug Metab Dispos 39:484-489.
    • (2011) Drug Metab Dispos , vol.39 , pp. 484-489
    • Taguchi, K.1    Iwao, Y.2    Watanabe, H.3    Kadowaki, D.4    Sakai, H.5    Kobayashi, K.6
  • 55
    • 67349215150 scopus 로고    scopus 로고
    • Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model
    • Taguchi, K., Maruyama, T., Iwao, Y., Sakai, H., Kobayashi, K., Horinouchi, H., et al. (2009a). Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model. J Contr Rel 136:232-239.
    • (2009) J Contr Rel , vol.136 , pp. 232-239
    • Taguchi, K.1    Maruyama, T.2    Iwao, Y.3    Sakai, H.4    Kobayashi, K.5    Horinouchi, H.6
  • 56
    • 77957226817 scopus 로고    scopus 로고
    • Hepatically-metabolized and-excreted artifcial oxygen carrier, hemoglobin-vesicles, can be safely used under conditions of hepatic impairment
    • Taguchi, K., Miyasato, M., Ujihira, H., Watanabe, H., Kadowaki, D., Sakai, H., et al. (2010). Hepatically-metabolized and-excreted artifcial oxygen carrier, hemoglobin-vesicles, can be safely used under conditions of hepatic impairment. Toxicol Appl Pharmacol 248:234-241.
    • (2010) Toxicol Appl Pharmacol , vol.248 , pp. 234-241
    • Taguchi, K.1    Miyasato, M.2    Ujihira, H.3    Watanabe, H.4    Kadowaki, D.5    Sakai, H.6
  • 57
    • 78650546620 scopus 로고    scopus 로고
    • Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupfer cell phagocyte activity
    • Taguchi, K., Miyasato, M., Watanabe, H., Sakai, H., Tsuchida, E., Horinouchi, H., et al. (2011b). Alteration in the pharmacokinetics of hemoglobin-vesicles in a rat model of chronic liver cirrhosis is associated with Kupfer cell phagocyte activity. J Pharm Sci 100:775-783.
    • (2011) J Pharm Sci , vol.100 , pp. 775-783
    • Taguchi, K.1    Miyasato, M.2    Watanabe, H.3    Sakai, H.4    Tsuchida, E.5    Horinouchi, H.6
  • 58
    • 67649415048 scopus 로고    scopus 로고
    • Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin vesicles as an artifcial oxygen carrier
    • Taguchi, K., Urata, Y., Anraku, M., Maruyama, T., Watanabe, H., Sakai, H., et al. (2009b). Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin vesicles as an artifcial oxygen carrier. Drug Metab Dispos 37:1456-1463.
    • (2009) Drug Metab Dispos , vol.37 , pp. 1456-1463
    • Taguchi, K.1    Urata, Y.2    Anraku, M.3    Maruyama, T.4    Watanabe, H.5    Sakai, H.6
  • 59
    • 70350277709 scopus 로고    scopus 로고
    • Hemoglobin vesicles, polyethylene glycol (PEG) ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice
    • Taguchi, K., Urata, Y., Anraku, M., Watanabe, H., Kadowaki, D., Sakai, H., et al. (2009c). Hemoglobin vesicles, polyethylene glycol (PEG) ylated liposomes developed as a red blood cell substitute, do not induce the accelerated blood clearance phenomenon in mice. Drug Metab Dispos 37:2197-2203.
    • (2009) Drug Metab Dispos , vol.37 , pp. 2197-2203
    • Taguchi, K.1    Urata, Y.2    Anraku, M.3    Watanabe, H.4    Kadowaki, D.5    Sakai, H.6
  • 60
    • 14644399831 scopus 로고    scopus 로고
    • Approach to clinical trial considering medical ethics and efficacy for HbV, liposome encapsulated hemoglobin vesicle
    • DOI 10.1081/BIO-200046695, Blood Substitutes
    • Takaori, M. (2005). Approach to clinical trial considering medical ethics and efcacy for HbV, liposome encapsulated hemoglobin vesicle. Artif Cells Blood Substit Immobil Biotechnol 33:65-73. (Pubitemid 40315179)
    • (2005) Artificial Cells, Blood Substitutes, and Immobilization Biotechnology , vol.33 , Issue.1 , pp. 65-73
    • Takaori, M.1
  • 61
    • 33646807837 scopus 로고    scopus 로고
    • Fluid resuscitation with hemoglobin vesicles in a rabbit model of acute hemorrhagic shock
    • Terajima, K., Tsueshita, T., Sakamoto, A., Ogawa, R. (2006). Fluid resuscitation with hemoglobin vesicles in a rabbit model of acute hemorrhagic shock. Shock 25:184-189.
    • (2006) Shock , vol.25 , pp. 184-189
    • Terajima, K.1    Tsueshita, T.2    Sakamoto, A.3    Ogawa, R.4
  • 62
    • 0030444355 scopus 로고    scopus 로고
    • Pharmacokinetics of meloxicam in patients with end-stage renal failure on haemodialysis: A comparison with healthy volunteers
    • Turck, D., Schwarz, A., Hofer, D., Narjes, H. H., Nehmiz, G., Heinzel, G. (1996). Pharmacokinetics of meloxicam in patients with end-stage renal failure on haemodialysis: a comparison with healthy volunteers. Eur J Clin Pharmacol 51:309-313.
    • (1996) Eur J Clin Pharmacol , vol.51 , pp. 309-313
    • Turck, D.1    Schwarz, A.2    Hofer, D.3    Narjes, H.H.4    Nehmiz, G.5    Heinzel, G.6
  • 64
    • 34248589255 scopus 로고    scopus 로고
    • Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes
    • DOI 10.1016/j.jconrel.2007.02.010, PII S0168365907001162
    • Wang, X., Ishida, T., Kiwada, H. (2007). Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes. J Contr Rel 119:236-244. (Pubitemid 46759557)
    • (2007) Journal of Controlled Release , vol.119 , Issue.2 , pp. 236-244
    • Wang, X.1    Ishida, T.2    Kiwada, H.3
  • 65
    • 57149095492 scopus 로고    scopus 로고
    • Systemic administration of hemoglobin vesicle elevates tumor tissue oxygen tension and modifes tumor response to irradiation
    • Yamamoto, M., Izumi, Y., Horinouchi, H., Teramura, Y., Sakai, H., Kohno, M., et al. (2009). Systemic administration of hemoglobin vesicle elevates tumor tissue oxygen tension and modifes tumor response to irradiation. J Surg Res 151:48-54.
    • (2009) J Surg Res , vol.151 , pp. 48-54
    • Yamamoto, M.1    Izumi, Y.2    Horinouchi, H.3    Teramura, Y.4    Sakai, H.5    Kohno, M.6
  • 66
    • 33747159627 scopus 로고    scopus 로고
    • Use of hemoglobin vesicles during cardiopulmonary bypass priming prevents neurocognitive decline in rats
    • DOI 10.1161/CIRCULATIONAHA.105.000562, PII 0000301720060704100036
    • Yamazaki, M., Aeba, R., Yozu, R., Kobayashi, K. (2006). Use of hemoglobin vesicles during cardiopulmonary bypass priming prevents neurocognitive decline in rats. Circulation 114:I220-I225 (Pubitemid 44297154)
    • (2006) Circulation , vol.114 , Issue.SUPPL. 1
    • Yamazaki, M.1    Aeba, R.2    Yozu, R.3    Kobayashi, K.4
  • 67
    • 1842467149 scopus 로고
    • Efect of hemorrhagic shock on the phagocytic function of Kupfer cells
    • Zweifach, B. W., Benacerraf, B. (1958). Efect of hemorrhagic shock on the phagocytic function of Kupfer cells. Circ Res 6:83-87.
    • (1958) Circ Res , vol.6 , pp. 83-87
    • Zweifach, B.W.1    Benacerraf, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.