Does hyperlipidemia injure the kidney?

Nature Clinical Practice Nephrology

Volumn 4, Issue 8, 2008, Pages 424-425

  Gröne, Elisabeth F ^a   Gröne, Hermann Josef ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

FOCAL GLOMERULOSCLEROSIS; HUMAN; HYPERLIPIDEMIA; KIDNEY INJURY; LIPID DIET; LIPID OXIDATION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SHORT SURVEY; TRANSCRIPTION REGULATION;

ANIMALS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; HYPERLIPIDEMIAS; KIDNEY; KIDNEY DISEASES; KIDNEY GLOMERULUS; REACTIVE OXYGEN SPECIES;

EID: 47949102936     PISSN: 17458323     EISSN: 17458331     Source Type: Journal    
DOI: 10.1038/ncpneph0863     Document Type: Short Survey

References (12)

1. Moorhead JF et al. (1982) Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease. Lancet 2: 1309-1311
2. Gröne EF et al. (1994) The role of lipids in nephrosclerosis and glomerulosclerosis. Atherosclerosis 107: 1-13
3. Kasiske BL et al. (1990) Renal injury of diet-induced hypercholesterolemia in rats. Kidney Int 37: 880-891
4. van Goor H et al. (1991) Determinants of focal and segmental glomerulosclerosis in the rat after renal ablation: evidence for involvement of macrophages and lipids. Lab Invest 64: 754-765
5. Gröne HJ et al. (1989) Induction of glomerulosclerosis by dietary lipids: a functional and morphologic study in the rat. Lab Invest 60: 433-446
6. Chen Y et al. (2007) Inflammatory cytokines disrupt LDL-receptor feedback regulation and cause statin resistance: a comparative study in human hepatic cells and mesangial cells. Am J Physiol Renal Physiol 293: F680-F687
7. Neale TJ et al. (1994) Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen. J Clin Invest 94: 1577-1584
8. Scheuer H et al. (2000) Oxidant stress in hyperlipidemia-induced renal damage. Am J Physiol Renal Physiol 278: F63-F74
9. Gwinner W et al. (2006) Pivotal role of xanthine oxidase in the initiation of tubulointerstitial renal injury in rats with hyperlipidemia. Kidney Int 69: 481-487
10. Porubsky S et al. (2004) Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium. Am J Pathol 164: 2175-2187
11. Hotamisligil GS (2007) Inflammation and metabolic disorders. Nature 444: 860-867
12. Cases A and Coll E (2005) Dyslipidemia and the progression of renal disease in chronic renal failure patients. Kidney Int Suppl 68: S87-S93