Drug transporter-independent liver cancer cell killing by a marine steroid methyl spongoate via apoptosis induction

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26461-26469

  Jiang, Yi ^a   Miao, Ze Hong ^a   Xu, Lei ^a   Yu, Bing ^a   Gong, Jing Xu ^a   Tong, Lin Jiang ^a   Chen, Yi ^a   Zhou, Zhao Li ^a   Liu, Hong Chun ^a   Wang, Yi ^a   Guo, Yue Wei ^a   Ding, Jian ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-APOPTOTIC PROTEIN; ANTIAPOPTOTIC; ANTICANCER DRUG; APOPTOSIS INDUCTION; CANDIDATE DRUGS; CASPASES; CELL KILLING; CELL LINES; CELL-CYCLE PROGRESSION; DRUG RESISTANCE; HEPATOCELLULAR CARCINOMA; INDUCED APOPTOSIS; LIVER CANCER CELLS; MICROTUBULES; MULTIDRUG-RESISTANT CANCER CELLS; PROAPOPTOTIC PROTEIN BAX; SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTIONS; TOPOISOMERASES; X-LINKED INHIBITOR OF APOPTOSIS;

CELL CULTURE; CELL DEATH; DISEASES; ENZYME INHIBITION; PHOSPHORYLATION; PROTEINS; SIGNALING;

DRUG THERAPY;

ANDROGEN; CASPASE; DNA TOPOISOMERASE; ESTROGEN; METHYL SPONGOATE; PROTEIN BAX; STAT3 PROTEIN; STEROID; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL CYCLE PROGRESSION; CELL KILLING; CELL PROLIFERATION; CONTROLLED STUDY; LIVER CELL CARCINOMA; MICROTUBULE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANDROGENS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ESTROGENS; HUMANS; LIVER NEOPLASMS; STAT3 TRANSCRIPTION FACTOR; STEROIDS;

EID: 79960694150     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.232728     Document Type: Article

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