-
1
-
-
0031048958
-
Treatment of hepatocellular carcinoma: A systematic review of randomized controlled trials
-
Simonetti RG, Liberati A, Angiolini C, et al. Treatment of hepatocellular carcinoma: A systematic review of randomized controlled trials. Ann Oncol 1997;8:117-136.
-
(1997)
Ann Oncol
, vol.8
, pp. 117-136
-
-
Simonetti, R.G.1
Liberati, A.2
Angiolini, C.3
-
2
-
-
0034100195
-
Expression of P-glycoprotein in hepatocellular carcinoma. A determinant of chemotherapy response
-
Ng IO, Liu CL, Fan ST, et al. Expression of P-glycoprotein in hepatocellular carcinoma. A determinant of chemotherapy response. Am J Clin Pathol 2000;113:355-363.
-
(2000)
Am J Clin Pathol
, vol.113
, pp. 355-363
-
-
Ng, I.O.1
Liu, C.L.2
Fan, S.T.3
-
3
-
-
0024329881
-
The biochemistry of P-glycoproteinmediated drug resistance
-
Endicott JA, Ling V. The biochemistry of P-glycoproteinmediated drug resistance. Annu Rev Biochem 1989;58:137-171.
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
4
-
-
0028334832
-
MDR1 gene expression: Its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines
-
Park JG, Lee SK, Hong IG, et al. MDR1 gene expression: Its effect on drug resistance to doxorubicin in human hepatocellular carcinoma cell lines. J Natl Cancer Inst 1994;86:700-705.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 700-705
-
-
Park, J.G.1
Lee, S.K.2
Hong, I.G.3
-
5
-
-
34447631489
-
Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells
-
Tsang WP, Kwok TT. Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells. Oncogene 2007;26:4877-4881.
-
(2007)
Oncogene
, vol.26
, pp. 4877-4881
-
-
Tsang, W.P.1
Kwok, T.T.2
-
6
-
-
2542424899
-
Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line
-
Chan KT, Lung ML. Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line. Cancer Chemother Pharmacol 2004;53:519-526.
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 519-526
-
-
Chan, K.T.1
Lung, M.L.2
-
7
-
-
33645092643
-
Hepatocyte growth factor and inducible nitric oxide synthase are involved in multidrug resistance-induced angiogenesis in hepatocellular carcinoma cell lines
-
Lasagna N, Fantappie O, Solazzo M, et al. Hepatocyte growth factor and inducible nitric oxide synthase are involved in multidrug resistance-induced angiogenesis in hepatocellular carcinoma cell lines. Cancer Res 2006;66:2673-2682.
-
(2006)
Cancer Res
, vol.66
, pp. 2673-2682
-
-
Lasagna, N.1
Fantappie, O.2
Solazzo, M.3
-
8
-
-
31344462626
-
Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells
-
Zhu H, Chen XP, Luo SF, et al. Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells. J Exp Clin Cancer Res 2005;24:565-574.
-
(2005)
J Exp Clin Cancer Res
, vol.24
, pp. 565-574
-
-
Zhu, H.1
Chen, X.P.2
Luo, S.F.3
-
9
-
-
0035845016
-
Atypical multidrug resistance may be associated with catalytically active mutants of human DNA topoisomerase II alpha
-
Okada Y, Tosaka A, Nimura Y, et al. Atypical multidrug resistance may be associated with catalytically active mutants of human DNA topoisomerase II alpha. Gene (Amst) 2001;272:141-148.
-
(2001)
Gene (Amst)
, vol.272
, pp. 141-148
-
-
Okada, Y.1
Tosaka, A.2
Nimura, Y.3
-
10
-
-
0036327669
-
Prognostic significance of DNA topoisomerase II alpha expression in human hepatocellular carcinoma
-
Watanuki A, Ohwada S, Fukusato T, et al. Prognostic significance of DNA topoisomerase II alpha expression in human hepatocellular carcinoma. Anticancer Res 2002;22:1113-1119.
-
(2002)
Anticancer Res
, vol.22
, pp. 1113-1119
-
-
Watanuki, A.1
Ohwada, S.2
Fukusato, T.3
-
11
-
-
0033087904
-
Expressions of epidermal growth factor family and its receptor in hepatocellular carcinoma cell lines: Relationship to cell proliferation
-
Hisaka T, Yano H, Haramaki M, et al. Expressions of epidermal growth factor family and its receptor in hepatocellular carcinoma cell lines: relationship to cell proliferation. Int J Oncol 1999;14:453-460.
-
(1999)
Int J Oncol
, vol.14
, pp. 453-460
-
-
Hisaka, T.1
Yano, H.2
Haramaki, M.3
-
12
-
-
0026267171
-
Growth factors in liver development, regeneration and carcinogenesis
-
Fausto N. Growth factors in liver development, regeneration and carcinogenesis. Prog Growth Factor Res 1991;3:219-234.
-
(1991)
Prog Growth Factor Res
, vol.3
, pp. 219-234
-
-
Fausto, N.1
-
13
-
-
9644255742
-
Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma
-
Hopfner M, Sutter AP, Huether A, et al. Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma. J Hepatol 41:1008-1016, 2004.
-
(2004)
J Hepatol
, vol.41
, pp. 1008-1016
-
-
Hopfner, M.1
Sutter, A.P.2
Huether, A.3
-
14
-
-
24344489502
-
Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics
-
Huether A, Hopfner M, Sutter AP, et al. Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics. J Hepatol 2005;43:661-669.
-
(2005)
J Hepatol
, vol.43
, pp. 661-669
-
-
Huether, A.1
Hopfner, M.2
Sutter, A.P.3
-
15
-
-
34548150925
-
Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma
-
Thomas MB, Chadha R, Glover K, et al. Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma. Cancer (Phila) 2007;110:1059-1067.
-
(2007)
Cancer (Phila)
, vol.110
, pp. 1059-1067
-
-
Thomas, M.B.1
Chadha, R.2
Glover, K.3
-
16
-
-
27244447373
-
Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer
-
Philip PA, Mahoney MR, Allmer C, et al. Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancer. J Clin Oncol 2005;23:6657-6663.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6657-6663
-
-
Philip, P.A.1
Mahoney, M.R.2
Allmer, C.3
-
17
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996;86:353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
18
-
-
0004623809
-
Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis
-
Park YN, Kim YB, Yang KM, et al. Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis. Arch Pathol Lab Med 2000;124:1061-1065.
-
(2000)
Arch Pathol Lab Med
, vol.124
, pp. 1061-1065
-
-
Park, Y.N.1
Kim, Y.B.2
Yang, K.M.3
-
19
-
-
0037833529
-
Vascular endothelial growth factor expression in serum of patients with hepatocellular carcinoma
-
Zhao J, Hu J, Cai J, et al. Vascular endothelial growth factor expression in serum of patients with hepatocellular carcinoma. Chin Med J (Engl) 2003;116:772-776.
-
(2003)
Chin Med J (Engl)
, vol.116
, pp. 772-776
-
-
Zhao, J.1
Hu, J.2
Cai, J.3
-
20
-
-
17144364359
-
Expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival
-
Huang GW, Yang LY, Lu WQ. Expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor in hepatocellular carcinoma: impact on neovascularization and survival. World J Gastroenterol 2005;11:1705-1708.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 1705-1708
-
-
Huang, G.W.1
Yang, L.Y.2
Lu, W.Q.3
-
21
-
-
16644364559
-
Expression of vascular endothelial growth factor in hepatocellular carcinoma and the surrounding liver: Correlation with angiographically assisted CT
-
Kanematsu M, Osada S, Amaoka N, et al. Expression of vascular endothelial growth factor in hepatocellular carcinoma and the surrounding liver: Correlation with angiographically assisted CT. AJR Am J Roentgenol 2004;183:1585-1593.
-
(2004)
AJR Am J Roentgenol
, vol.183
, pp. 1585-1593
-
-
Kanematsu, M.1
Osada, S.2
Amaoka, N.3
-
22
-
-
31944434717
-
Magnetic resonance imaging and expression of vascular endothelial growth factor in hepatocellular nodules in cirrhosis and hepatocellular carcinomas
-
Kanematsu M, Semelka RC, Osada S, et al. Magnetic resonance imaging and expression of vascular endothelial growth factor in hepatocellular nodules in cirrhosis and hepatocellular carcinomas. Top Magn Reson Imaging 2005;16:67-75.
-
(2005)
Top Magn Reson Imaging
, vol.16
, pp. 67-75
-
-
Kanematsu, M.1
Semelka, R.C.2
Osada, S.3
-
23
-
-
26044455743
-
Correlative study of angiogenesis and dynamic contrast-enhanced magnetic resonance imaging features of hepatocellular carcinoma
-
Wang B, Gao ZQ, Yan X. Correlative study of angiogenesis and dynamic contrast-enhanced magnetic resonance imaging features of hepatocellular carcinoma. Acta Radiol 2005;46:353-358.
-
(2005)
Acta Radiol
, vol.46
, pp. 353-358
-
-
Wang, B.1
Gao, Z.Q.2
Yan, X.3
-
25
-
-
0031171663
-
Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization
-
Kenyon BM, Browne F, D'Amato RJ. Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization. Exp Eye Res 1997;64:971-978.
-
(1997)
Exp Eye Res
, vol.64
, pp. 971-978
-
-
Kenyon, B.M.1
Browne, F.2
D'Amato, R.J.3
-
26
-
-
2942711726
-
Thalidomid: Current role in the treatment of non-plasma cell malignancies
-
Kumar S, Witzig TE, Rajkumar SV. Thalidomid: Current role in the treatment of non-plasma cell malignancies. J Clin Oncol 2004;22:2477-2488.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2477-2488
-
-
Kumar, S.1
Witzig, T.E.2
Rajkumar, S.V.3
-
27
-
-
0344305652
-
Low-dose thalidomide treatment for advanced hepatocellular carcinoma
-
Hsu C, Chen CN, Chen LT, et al. Low-dose thalidomide treatment for advanced hepatocellular carcinoma. Oncology 2003;65:242-249.
-
(2003)
Oncology
, vol.65
, pp. 242-249
-
-
Hsu, C.1
Chen, C.N.2
Chen, L.T.3
-
28
-
-
1542790477
-
Salvage therapy for hepatocellular carcinoma with thalidomide
-
Wang TE, Kao CR, Lin SC, et al. Salvage therapy for hepatocellular carcinoma with thalidomide. World J Gastroenterol 2004;10:649-653.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 649-653
-
-
Wang, T.E.1
Kao, C.R.2
Lin, S.C.3
-
29
-
-
10844248554
-
Phase II study of thalidomide in patients with unresectable hepatocellular carcinoma
-
Lin AY, Brophy N, Fisher GA, et al. Phase II study of thalidomide in patients with unresectable hepatocellular carcinoma. Cancer (Phila) 2005;103:119-125.
-
(2005)
Cancer (Phila)
, vol.103
, pp. 119-125
-
-
Lin, A.Y.1
Brophy, N.2
Fisher, G.A.3
-
30
-
-
13444303839
-
Thalidomide in the treatment of patients with hepatocellular carcinoma: A phase II trial
-
Patt YZ, Hassan MM, Lozano RD, et al. Thalidomide in the treatment of patients with hepatocellular carcinoma: A phase II trial. Cancer (Phila) 2005;103:749-755.
-
(2005)
Cancer (Phila)
, vol.103
, pp. 749-755
-
-
Patt, Y.Z.1
Hassan, M.M.2
Lozano, R.D.3
-
31
-
-
27644485445
-
Thalidomide in advanced hepatocellular carcinoma with optional low-dose interferonalpha2a upon progression
-
Schwartz JD, Sung M, Schwartz M, et al. Thalidomide in advanced hepatocellular carcinoma with optional low-dose interferonalpha2a upon progression. Oncologist 2005;10:718-727.
-
(2005)
Oncologist
, vol.10
, pp. 718-727
-
-
Schwartz, J.D.1
Sung, M.2
Schwartz, M.3
-
32
-
-
33746624000
-
Systemic therapy of advanced hepatocellular carcinoma: How hopeful should we be?
-
Zhu AX. Systemic therapy of advanced hepatocellular carcinoma: How hopeful should we be? Oncologist 2006;11:790-800.
-
(2006)
Oncologist
, vol.11
, pp. 790-800
-
-
Zhu, A.X.1
-
33
-
-
22244436300
-
A phase II study of epirubicin and thalidomide in unresectable or metastatic hepatocellular carcinoma
-
Zhu AX, Fuchs CS, Clark JW, et al. A phase II study of epirubicin and thalidomide in unresectable or metastatic hepatocellular carcinoma. Oncologist 2005;10:392-398.
-
(2005)
Oncologist
, vol.10
, pp. 392-398
-
-
Zhu, A.X.1
Fuchs, C.S.2
Clark, J.W.3
-
36
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
Abou-Alfa GK, Schwartz L, Ricci S, et al. Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006;24:4293-4300.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
-
37
-
-
34548720158
-
Sorafenib improves survival in advanced hepatocellular carcinoma (HCC): Results of a Phase III randomized placebo-controlled trial (SHARP trial)
-
Llovet J, Ricci S, et al. Sorafenib improves survival in advanced hepatocellular carcinoma (HCC): Results of a Phase III randomized placebo-controlled trial (SHARP trial). ASCO Annual Meeting Proceedings, Part I. J Clin Oncol 25:ABA1.
-
ASCO Annual Meeting Proceedings, Part I. J Clin Oncol
, vol.25
-
-
Llovet, J.1
Ricci, S.2
-
38
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy. Nat Med 2001;7:987-989.
-
(2001)
Nat Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
39
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett CG, Boucher Y, di Tomaso E, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004;10:145-147.
-
(2004)
Nat Med
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
di Tomaso, E.3
-
40
-
-
33750917456
-
Bevacizumab in unresectable hepatocellular carcinoma (HCC) for patients without metastasis and without invasion of the portal vein
-
Schwartz MS, Lehrer D, Cohen E, Sung M, Kinkhabwala M, Siegel A, et al. Bevacizumab in unresectable hepatocellular carcinoma (HCC) for patients without metastasis and without invasion of the portal vein. ASCO Annual Meeting Proceedings. J Clin Oncol 2006;24(18 suppl):A4144.
-
(2006)
ASCO Annual Meeting Proceedings. J Clin Oncol
, vol.24
, Issue.18 SUPPL.
-
-
Schwartz, M.S.1
Lehrer, D.2
Cohen, E.3
Sung, M.4
Kinkhabwala, M.5
Siegel, A.6
-
41
-
-
38049092474
-
Bevacizumab in patients (pts) with advanced hepatocellular carcinoma (HCC): Preliminary results of a phase II study with circulating endothelial cell (CEC) monitoring
-
Malka D, Dromain C, Farace F, et al. Bevacizumab in patients (pts) with advanced hepatocellular carcinoma (HCC): Preliminary results of a phase II study with circulating endothelial cell (CEC) monitoring. ASCO Annual Proceedings, Part I. J Clin Oncol 2007;25:A4570.
-
(2007)
ASCO Annual Proceedings, Part I. J Clin Oncol
, vol.25
-
-
Malka, D.1
Dromain, C.2
Farace, F.3
-
42
-
-
33646351795
-
Phase II study of gemcitabine and oxaliplatin in combination with bevacizumab in patients with advanced hepatocellular carcinoma
-
Zhu AX, Blaszkowsky LS, Ryan DP, et al. Phase II study of gemcitabine and oxaliplatin in combination with bevacizumab in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006;24:1898-1903.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1898-1903
-
-
Zhu, A.X.1
Blaszkowsky, L.S.2
Ryan, D.P.3
-
43
-
-
42049095494
-
Modified-dose capecitabine + bevacizumab for the treatment of advanced/ metastatic hepatocellular carcinoma (HCC): A phase II, single-arm study
-
Hsu C, Hsu C, Yang T, et al. Modified-dose capecitabine + bevacizumab for the treatment of advanced/metastatic hepatocellular carcinoma (HCC): a phase II, single-arm study. ASCO Annual Proceedings, Part I. J Clin Oncol 2007;25:A15190.
-
(2007)
ASCO Annual Proceedings, Part I. J Clin Oncol
, vol.25
-
-
Hsu, C.1
Hsu, C.2
Yang, T.3
-
44
-
-
36549089272
-
Combination of capecitabine, oxaliplatin with bevacizumab in treatment of advanced hepatocellular carcinoma (HCC): A phase II study
-
Sun W, Haller DG, Mykulowycz K, et al. Combination of capecitabine, oxaliplatin with bevacizumab in treatment of advanced hepatocellular carcinoma (HCC): A phase II study. ASCO Annual Proceedings, Part I. J Clin Oncol 2007;25:A4574.
-
(2007)
ASCO Annual Proceedings, Part I. J Clin Oncol
, vol.25
-
-
Sun, W.1
Haller, D.G.2
Mykulowycz, K.3
-
45
-
-
36549072713
-
The combination of bevacizumab (B) and erlotinib (E) shows significant biological activity in patients with advanced hepatocellular carcinoma
-
Thomas MB, Chadha R, Iwasaki M, et al. The combination of bevacizumab (B) and erlotinib (E) shows significant biological activity in patients with advanced hepatocellular carcinoma. ASCO Annual Proceedings, Part I. J Clin Oncol 2007;25:A4567.
-
(2007)
ASCO Annual Proceedings, Part I. J Clin Oncol
, vol.25
-
-
Thomas, M.B.1
Chadha, R.2
Iwasaki, M.3
-
46
-
-
27644508837
-
Resveratrol inhibits hypoxiainduced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells
-
Zhang Q, Tang X, Lu QY, et al. Resveratrol inhibits hypoxiainduced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells. Mol Cancer Ther 2005;4:1465-1474.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1465-1474
-
-
Zhang, Q.1
Tang, X.2
Lu, Q.Y.3
-
47
-
-
23844470405
-
Functional expression of a proliferation-related ligand in hepatocellular carcinoma and its implications for neovascularization
-
Okano H, Shiraki K, Yamanaka Y, et al. Functional expression of a proliferation-related ligand in hepatocellular carcinoma and its implications for neovascularization. World J Gastroenterol 2005;11:4650-4654.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 4650-4654
-
-
Okano, H.1
Shiraki, K.2
Yamanaka, Y.3
-
48
-
-
0032878376
-
Increased activity and expression of MAP kinase in HCC model rats induced by 3′-methyl-4-dimethylamino-azobenzene
-
Toyoda M, Hashimoto N, Tokita K, et al. Increased activity and expression of MAP kinase in HCC model rats induced by 3′-methyl-4-dimethylamino-azobenzene. J Hepatol 1999;31:725-733.
-
(1999)
J Hepatol
, vol.31
, pp. 725-733
-
-
Toyoda, M.1
Hashimoto, N.2
Tokita, K.3
-
49
-
-
0030715557
-
Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma
-
McKillop IH, Schmidt CM, Cahill PA, et al. Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma. Hepatology 1997;26:1484-1491.
-
(1997)
Hepatology
, vol.26
, pp. 1484-1491
-
-
McKillop, I.H.1
Schmidt, C.M.2
Cahill, P.A.3
-
50
-
-
17344372847
-
Activation of mitogenactivated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma
-
Ito Y, Sasaki Y, Horimoto M, et al. Activation of mitogenactivated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology 1998;27:951-958.
-
(1998)
Hepatology
, vol.27
, pp. 951-958
-
-
Ito, Y.1
Sasaki, Y.2
Horimoto, M.3
-
51
-
-
0035113393
-
Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance
-
Feng DY, Zheng H, Tan Y, et al. Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 2001;7:33-36.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 33-36
-
-
Feng, D.Y.1
Zheng, H.2
Tan, Y.3
-
52
-
-
20344404979
-
Farnesyltransferase inhibitor, ABT-100, is a potent liver cancer chemopreventive agent
-
Carloni V, Vizzutti F, Pantaleo P. Farnesyltransferase inhibitor, ABT-100, is a potent liver cancer chemopreventive agent. Clin Cancer Res 2005;11:4266-4274.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4266-4274
-
-
Carloni, V.1
Vizzutti, F.2
Pantaleo, P.3
-
53
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008;359:378-390.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
-
54
-
-
34247606468
-
Pleiotropic effects of PI-3′ kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosis
-
Alexia C, Bras M, Fallot G, et al. Pleiotropic effects of PI-3′ kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosis. Ann N Y Acad Sci 2006;1090:1-17.
-
(2006)
Ann N Y Acad Sci
, vol.1090
, pp. 1-17
-
-
Alexia, C.1
Bras, M.2
Fallot, G.3
-
55
-
-
34047250349
-
Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells
-
Saxena NK, Sharma D, Ding X, et al. Concomitant activation of the JAK/ STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. Cancer Res 2007;67:2497-2507.
-
(2007)
Cancer Res
, vol.67
, pp. 2497-2507
-
-
Saxena, N.K.1
Sharma, D.2
Ding, X.3
-
56
-
-
23944480924
-
Treating cancer by blocking cell signals
-
Adjei AA, Hidalgo M. Treating cancer by blocking cell signals. J Clin Oncol 2005;23:5279-5280.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5279-5280
-
-
Adjei, A.A.1
Hidalgo, M.2
-
57
-
-
11144236505
-
mTOR and P70 S6 kinase expression in primary liver neoplasms
-
Sahin F, Kannangai R, Adegbola O, et al. mTOR and P70 S6 kinase expression in primary liver neoplasms. Clin Cancer Res 2004;10:8421-8425.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8421-8425
-
-
Sahin, F.1
Kannangai, R.2
Adegbola, O.3
-
58
-
-
33947501692
-
Mammalian target of rapamycin pathway activity in hepatocellular carcinomas of patients undergoing liver transplantation
-
Sieghart W, Fuereder T, Schmid K, et al. Mammalian target of rapamycin pathway activity in hepatocellular carcinomas of patients undergoing liver transplantation. Transplantation 2007;83:425-432.
-
(2007)
Transplantation
, vol.83
, pp. 425-432
-
-
Sieghart, W.1
Fuereder, T.2
Schmid, K.3
-
59
-
-
27144557565
-
A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma
-
Yeo W, Mok TS, Zee B, et al. A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J Natl Cancer Inst 2005;97:1532-1538.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1532-1538
-
-
Yeo, W.1
Mok, T.S.2
Zee, B.3
-
60
-
-
0032798501
-
A multi-centre randomized phase II study of nolatrexed versus doxorubicin in treatment of Chinese patients with advanced hepatocellular carcinoma
-
Mok TS, Leung TW, Lee SD, et al. A multi-centre randomized phase II study of nolatrexed versus doxorubicin in treatment of Chinese patients with advanced hepatocellular carcinoma. Cancer Chemother Pharmacol 1999;44:307-311.
-
(1999)
Cancer Chemother Pharmacol
, vol.44
, pp. 307-311
-
-
Mok, T.S.1
Leung, T.W.2
Lee, S.D.3
-
61
-
-
33646575196
-
Results of a phase 2/3 open-label, randomized trial of T138067 versus doxorubicin (DOX) in chemotherapy-naïve, unresectable hepatocellular carcinoma (HCC)
-
Posey JJP, Mok T, et al. Results of a phase 2/3 open-label, randomized trial of T138067 versus doxorubicin (DOX) in chemotherapy-naïve, unresectable hepatocellular carcinoma (HCC). J Clin Oncol 2005;23(suppl):4035.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
, pp. 4035
-
-
Posey, J.J.P.1
Mok, T.2
-
62
-
-
34547662913
-
Phase III randomized controlled trial comparing the survival of patients with unresectable hepatocellular carcinoma treated with nolatrexed or doxorubicin
-
Gish RG, Porta C, Lazar L, et al. Phase III randomized controlled trial comparing the survival of patients with unresectable hepatocellular carcinoma treated with nolatrexed or doxorubicin. J Clin Oncol 2007;25:3069-3075.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3069-3075
-
-
Gish, R.G.1
Porta, C.2
Lazar, L.3
-
63
-
-
40549098471
-
A phase II study of pegylated liposomial doxorubicin (PLD) and gemcitabine (G) in the treatment of hepatocellular carcinoma (HCC) not suitable for locoregional therapy
-
Pastorelli DCG, Zustovich F, et al. A phase II study of pegylated liposomial doxorubicin (PLD) and gemcitabine (G) in the treatment of hepatocellular carcinoma (HCC) not suitable for locoregional therapy. J Clin Oncol 2007;25(suppl):4585.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
, pp. 4585
-
-
Pastorelli, D.C.G.1
Zustovich, F.2
-
64
-
-
36549072713
-
The combination of bevacizumab (B) and erlotinib (E) shows significant biological activity in patients with advanced hepatocellular carcinoma (HCC)
-
Thomas MBCR, Iwasaki M, et al. The combination of bevacizumab (B) and erlotinib (E) shows significant biological activity in patients with advanced hepatocellular carcinoma (HCC). J Clin Oncol 2007;25(suppl):4567.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
, pp. 4567
-
-
Thomas, M.B.C.R.1
Iwasaki, M.2
-
65
-
-
33750915657
-
Phase II study of lapatinib, a dual inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase 1 and 2 (Her2/Neu) in patients (pts) with advanced biliary tree cancer (BTC) or hepatocellular cancer (HCC). A California Consortium (CCC-P) Trial
-
Ramanathan CPB, Singh DA, et al. Phase II study of lapatinib, a dual inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase 1 and 2 (Her2/Neu) in patients (pts) with advanced biliary tree cancer (BTC) or hepatocellular cancer (HCC). A California Consortium (CCC-P) Trial. J Clin Oncol 2006;24(18 suppl):4010.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 SUPPL.
, pp. 4010
-
-
Ramanathan, C.P.B.1
Singh, D.A.2
-
66
-
-
58849086599
-
A phase II open-label study of cetuximab in unresectable hepatocellular carcinoma
-
Gruenwald LW, Gebel M, et al. A phase II open-label study of cetuximab in unresectable hepatocellular carcinoma. J Clin Oncol 2006;24(18 suppl):14079.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 SUPPL.
, pp. 14079
-
-
Gruenwald, L.W.1
Gebel, M.2
-
67
-
-
33750928591
-
Phase II study of cetuximab in patients with unresectable or metastatic hepatocellular carcinoma
-
Zhu AXBL, Enzinger PC, et al. Phase II study of cetuximab in patients with unresectable or metastatic hepatocellular carcinoma. J Clin Oncol 2006;24(suppl):14096.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
, pp. 14096
-
-
Zhu, A.X.B.L.1
Enzinger, P.C.2
-
68
-
-
33750929534
-
Gefitinib in advanced unresectable hepatocellular carcinoma: Results from the Eastern Cooperative Oncology Group' Study E1203
-
O'Dwyer PJGB, Levy DE, et al. Gefitinib in advanced unresectable hepatocellular carcinoma: Results from the Eastern Cooperative Oncology Group's Study E1203. J Clin Oncol 2006;24(suppl):4143.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
, pp. 4143
-
-
O'Dwyer, P.J.G.B.1
Levy, D.E.2
-
69
-
-
36549089272
-
Combination of capecitabine, oxaliplatin with bevacizumab in treatment of advanced hepatocellular carcinoma (HCC): A phase II study
-
Sun WHD, Mykulowycz K, et al. Combination of capecitabine, oxaliplatin with bevacizumab in treatment of advanced hepatocellular carcinoma (HCC): A phase II study. J Clin Oncol 2007;25(suppl):4574.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
, pp. 4574
-
-
Sun, W.H.D.1
Mykulowycz, K.2
-
70
-
-
33947495362
-
Gemcitabine plus oxaliplatin (GEMOX) in patients with advanced hepatocellular carcinoma (HCC): Results of a phase II study
-
Louafi S, Boige V, Ducreux M, et al. Gemcitabine plus oxaliplatin (GEMOX) in patients with advanced hepatocellular carcinoma (HCC): results of a phase II study. Cancer (Phila) 2007;109:1384-1390.
-
(2007)
Cancer (Phila)
, vol.109
, pp. 1384-1390
-
-
Louafi, S.1
Boige, V.2
Ducreux, M.3
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