Antimicrobial activity and membrane selective interactions of a synthetic lipopeptide MSI-843

Biochimica et Biophysica Acta - Biomembranes

Volumn 1711, Issue 1, 2005, Pages 49-58

  Thennarasu, Sathiah ^a   Lee, Dong Kuk ^a   Tan, Anmin ^a   Kari, U Prasad ^b   Ramamoorthy, Ayyalusamy ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Genaera Pharmaceuticals   (United States)

Author keywords

Antimicrobial activity; Curvature strain; Lipopeptide; Membrane permeabilization; Oriented bilayers; Solid state NMR

Indexed keywords

1 PALMITOYL 2 OLEOYLGLYCERO 3 PHOSPHATIDYLGLYCEROL; 1,2 DIPALMITOLEOYLGLYCERO 3 PHOSPHATIDYLETHANOLAMINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; AMINO ACID DERIVATIVE; ANTIINFECTIVE AGENT; DEUTERIUM; DYE; ETHANOLAMINE DERIVATIVE; LIPOPEPTIDE; MSI 843; OCTANOIC ACID; ORNITHINE DERIVATIVE; PHOSPHATIDYLGLYCEROL; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DEUTERON NUCLEAR MAGNETIC RESONANCE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DESIGN; DRUG SCREENING; DRUG SELECTIVITY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; LIPID BILAYER; LIPID MEMBRANE; LIPID VESICLE; MEMBRANE BINDING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHASE TRANSITION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN LIPID INTERACTION; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

ANTI-BACTERIAL AGENTS; CALORIMETRY; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; ESCHERICHIA COLI; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; ORNITHINE; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; TEMPERATURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA; FUNGI; NEGIBACTERIA;

EID: 19444376974     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2005.02.010     Document Type: Article

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