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Volumn 77, Issue 2, 2011, Pages 174-178

The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; TRANSCRIPTION FACTOR NRF2;

EID: 79960623753     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2011.04.002     Document Type: Article
Times cited : (107)

References (54)
  • 2
    • 0036156424 scopus 로고    scopus 로고
    • Cyclooxygenase-2, 10 years later
    • Hinz B., Brune K. Cyclooxygenase-2, 10 years later. J Pharmacol Exp Ther 2002, 300(2):367-375.
    • (2002) J Pharmacol Exp Ther , vol.300 , Issue.2 , pp. 367-375
    • Hinz, B.1    Brune, K.2
  • 3
    • 33646895156 scopus 로고    scopus 로고
    • COX-1 and 2 expressions in sex-related organs of neonatally estrogen treated rats and in activated and non-activated macrophage RAW264.7 cells with phytoestrogen
    • Peng Luo.C., Santti Y., He ML R., Lin M.C. COX-1 and 2 expressions in sex-related organs of neonatally estrogen treated rats and in activated and non-activated macrophage RAW264.7 cells with phytoestrogen. Endocr. 2006, 29(1):161-167.
    • (2006) Endocr. , vol.29 , Issue.1 , pp. 161-167
    • Peng, L.1    Santti, Y.2    He, M.L.R.3    Lin, M.C.4
  • 4
    • 31044441042 scopus 로고    scopus 로고
    • Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities
    • Grosser T., Fries S., FitzGerald G.A. Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. J Clin Invest 2006, 116(1):4-15.
    • (2006) J Clin Invest , vol.116 , Issue.1 , pp. 4-15
    • Grosser, T.1    Fries, S.2    FitzGerald, G.A.3
  • 5
    • 2142695733 scopus 로고    scopus 로고
    • Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic
    • Warner T.D., Mitchell J.A. Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. FASEB J 2004, 18:790-804.
    • (2004) FASEB J , vol.18 , pp. 790-804
    • Warner, T.D.1    Mitchell, J.A.2
  • 6
    • 23844505961 scopus 로고    scopus 로고
    • Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial
    • Luo C., He M.L., Bohlin L. Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial. Acta Pharmacol Sin 2005, 26(8):926-933.
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.8 , pp. 926-933
    • Luo, C.1    He, M.L.2    Bohlin, L.3
  • 7
    • 0035934070 scopus 로고    scopus 로고
    • Risk of cardiovascular events associated with selective COX-2 Inhibitors
    • Mukherjee D., Nissen S.E., Topol E.J. Risk of cardiovascular events associated with selective COX-2 Inhibitors. JAMA 2001, 286:954-959.
    • (2001) JAMA , vol.286 , pp. 954-959
    • Mukherjee, D.1    Nissen, S.E.2    Topol, E.J.3
  • 8
    • 19744380776 scopus 로고    scopus 로고
    • Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
    • Bresalier R.S., Sandler R.S., Quan H., et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005, 352:1092-1102.
    • (2005) N Engl J Med , vol.352 , pp. 1092-1102
    • Bresalier, R.S.1    Sandler, R.S.2    Quan, H.3
  • 9
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999, 13(1):76-86.
    • (1999) Genes Dev , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6
  • 11
    • 70349801984 scopus 로고    scopus 로고
    • Regulation of Nrf2-dependent gene expression by 15-deoxy-Δ12, 14-prostaglandin J2
    • Kansanen E., Kivelä A.M., Levonen A.L. Regulation of Nrf2-dependent gene expression by 15-deoxy-Δ12, 14-prostaglandin J2. Free Radic Biol Med 2009, 47:1310-1317.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1310-1317
    • Kansanen, E.1    Kivelä, A.M.2    Levonen, A.L.3
  • 12
    • 40849085188 scopus 로고    scopus 로고
    • Lipid autacoids in inflammation and injury responses: A matter of privilege
    • Karsten G. Lipid autacoids in inflammation and injury responses: A matter of privilege. Mol Interv 2008, 8(1):28-35.
    • (2008) Mol Interv , vol.8 , Issue.1 , pp. 28-35
    • Karsten, G.1
  • 13
    • 77954611060 scopus 로고    scopus 로고
    • Structural basis of fatty acid substrate binding to cyclooxygenase-2
    • Vecchio A.J., Simmons D.M., Malkowski M.G. Structural basis of fatty acid substrate binding to cyclooxygenase-2. J Biol Chem 2010, 285(29):22152-22163.
    • (2010) J Biol Chem , vol.285 , Issue.29 , pp. 22152-22163
    • Vecchio, A.J.1    Simmons, D.M.2    Malkowski, M.G.3
  • 14
    • 77952499374 scopus 로고    scopus 로고
    • Lipids: COX-2's new role in inflammation
    • Chen C. Lipids: COX-2's new role in inflammation. Nat Chem Biol 2010, 6:401-402.
    • (2010) Nat Chem Biol , vol.6 , pp. 401-402
    • Chen, C.1
  • 15
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
    • Serhan C.N., Chiang N., Van Dyke T.E. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 2008, 8:349-361.
    • (2008) Nat Rev Immunol , vol.8 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 17
    • 3543008924 scopus 로고    scopus 로고
    • Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
    • Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., et al. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 2004, 24(16):7130-7139.
    • (2004) Mol Cell Biol , vol.24 , Issue.16 , pp. 7130-7139
    • Kobayashi, A.1    Kang, M.I.2    Okawa, H.3    Ohtsuji, M.4    Zenke, Y.5    Chiba, T.6
  • 18
    • 77949262414 scopus 로고    scopus 로고
    • Cysteine-based regulation of the CUL3 adaptor protein Keap1
    • Sekhar K.R., Rachakonda G., Freeman M.L. Cysteine-based regulation of the CUL3 adaptor protein Keap1. Toxicol Appl Pharmacol 2009, 244(1):21-26.
    • (2009) Toxicol Appl Pharmacol , vol.244 , Issue.1 , pp. 21-26
    • Sekhar, K.R.1    Rachakonda, G.2    Freeman, M.L.3
  • 20
    • 77649261371 scopus 로고    scopus 로고
    • Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains
    • Ogura T., Tong K.I., Mio K., Maruyama Y., Kurokawa H., Sato C., et al. Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains. Proc Natl Acad Sci USA 2010, 107(7):2842-2847.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.7 , pp. 2842-2847
    • Ogura, T.1    Tong, K.I.2    Mio, K.3    Maruyama, Y.4    Kurokawa, H.5    Sato, C.6
  • 21
    • 30444448695 scopus 로고    scopus 로고
    • Prostaglandins, bioassay and inflammation
    • Flower R.J. Prostaglandins, bioassay and inflammation. Br J Pharmacol 2006, 147:S182-S192.
    • (2006) Br J Pharmacol , vol.147
    • Flower, R.J.1
  • 22
    • 0034916569 scopus 로고    scopus 로고
    • Lipid mediator class switching during acute inflammation: signals in resolution
    • Levy B.D., Clish C.B., Schmidt B., Gronert K., Serhan C.N. Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol 2001, 2:612-619.
    • (2001) Nat Immunol , vol.2 , pp. 612-619
    • Levy, B.D.1    Clish, C.B.2    Schmidt, B.3    Gronert, K.4    Serhan, C.N.5
  • 24
    • 38049181031 scopus 로고    scopus 로고
    • Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxy 12-14 PGJ2
    • Rajakariar R., Hilliard M., Lawrence T., Trivedi S., Colville-Nash P., Bellingan G., et al. Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxy 12-14 PGJ2. Proc Natl Acad Sci USA 2007, 104:20979-20984.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20979-20984
    • Rajakariar, R.1    Hilliard, M.2    Lawrence, T.3    Trivedi, S.4    Colville-Nash, P.5    Bellingan, G.6
  • 25
    • 38049144323 scopus 로고    scopus 로고
    • Resolving the problem of persistence in the switch from acute to chronic inflammation
    • Haworth O., Buckley C.D. Resolving the problem of persistence in the switch from acute to chronic inflammation. Proc Natl Acad Sci USA 2007, 104:20647-20648.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20647-20648
    • Haworth, O.1    Buckley, C.D.2
  • 26
    • 77953228968 scopus 로고    scopus 로고
    • Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis
    • Kundu J.K., Surh Y.J. Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis. Pharm Res 2010, 27(6):999-1013.
    • (2010) Pharm Res , vol.27 , Issue.6 , pp. 999-1013
    • Kundu, J.K.1    Surh, Y.J.2
  • 27
    • 0035224729 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and -2 contribution to endothelial dysfunction in ageing
    • Heymes C., Habib A., Yang D., Mathieu E., Marotte F., Samuel J.L., et al. Cyclooxygenase-1 and -2 contribution to endothelial dysfunction in ageing. Br J Pharmacol 2000, 131(4):804-810.
    • (2000) Br J Pharmacol , vol.131 , Issue.4 , pp. 804-810
    • Heymes, C.1    Habib, A.2    Yang, D.3    Mathieu, E.4    Marotte, F.5    Samuel, J.L.6
  • 28
    • 18844439123 scopus 로고    scopus 로고
    • Ageing alters the production of nitric oxide and prostanoids after IL-1beta exposure in mesenteric resistance arteries
    • Briones A.M., Salaices M., Vila E. Ageing alters the production of nitric oxide and prostanoids after IL-1beta exposure in mesenteric resistance arteries. Mech Ageing Dev 2005, 126(6-7):710-721.
    • (2005) Mech Ageing Dev , vol.126 , Issue.6-7 , pp. 710-721
    • Briones, A.M.1    Salaices, M.2    Vila, E.3
  • 29
    • 79851512889 scopus 로고    scopus 로고
    • Small molecule modulators of antioxidant response pathway
    • Hur W., Gray N.S. Small molecule modulators of antioxidant response pathway. Curr Opin Chem Biol 2010, 15:1-12.
    • (2010) Curr Opin Chem Biol , vol.15 , pp. 1-12
    • Hur, W.1    Gray, N.S.2
  • 30
    • 41349118031 scopus 로고    scopus 로고
    • NF-κB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals
    • Surh Y.J., Na H.K. NF-κB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals. Genes Nutr 2008, 2:313-317.
    • (2008) Genes Nutr , vol.2 , pp. 313-317
    • Surh, Y.J.1    Na, H.K.2
  • 31
    • 0030472175 scopus 로고    scopus 로고
    • Impairment of vascular function is associated with an age-related increase of lipid peroxidation in rats
    • Davidge S.T., Hubel C.A., McLaughlin M.K. Impairment of vascular function is associated with an age-related increase of lipid peroxidation in rats. Am J Physiol 1996, 271:R1625.
    • (1996) Am J Physiol , vol.271
    • Davidge, S.T.1    Hubel, C.A.2    McLaughlin, M.K.3
  • 32
    • 0034048530 scopus 로고    scopus 로고
    • Aging increases PGHS-2-dependent vasoconstriction in rat mesenteric arteries
    • Stewart K.G., Zhang Y., Davidge S.T. Aging increases PGHS-2-dependent vasoconstriction in rat mesenteric arteries. Hypertension 2000, 35:1242.
    • (2000) Hypertension , vol.35 , pp. 1242
    • Stewart, K.G.1    Zhang, Y.2    Davidge, S.T.3
  • 33
    • 38749089857 scopus 로고    scopus 로고
    • Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats
    • Shi Y., Man R.Y., Vanhoutte P.M. Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats. Acta Pharmacol Sin 2008, 29(2):185-192.
    • (2008) Acta Pharmacol Sin , vol.29 , Issue.2 , pp. 185-192
    • Shi, Y.1    Man, R.Y.2    Vanhoutte, P.M.3
  • 34
    • 0028969650 scopus 로고
    • Prostaglandin H synthetase-mediated metabolism of dopamine: implication for Parkinson's disease
    • Mattammal M.M.B., Strong R., Lakshmi V.M., Chung H.D., Stephenson A.H. Prostaglandin H synthetase-mediated metabolism of dopamine: implication for Parkinson's disease. J Neurochem 1995, 64:1645-1654.
    • (1995) J Neurochem , vol.64 , pp. 1645-1654
    • Mattammal, M.M.B.1    Strong, R.2    Lakshmi, V.M.3    Chung, H.D.4    Stephenson, A.H.5
  • 36
    • 61749090102 scopus 로고    scopus 로고
    • COX-2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice
    • Vardeh D., Wang D., Costigan M., Lazarus M., Saper C.B., Woolf C.J., et al. COX-2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice. J Clin Invest 2009, 119(2):287-294.
    • (2009) J Clin Invest , vol.119 , Issue.2 , pp. 287-294
    • Vardeh, D.1    Wang, D.2    Costigan, M.3    Lazarus, M.4    Saper, C.B.5    Woolf, C.J.6
  • 37
    • 33645867671 scopus 로고    scopus 로고
    • Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease
    • Vijitruth R., Liu M., Choi D.Y., Nguyen X.V., Hunter R.L., Bing G. Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease. J Neuroinflamm 2006, 3:6.
    • (2006) J Neuroinflamm , vol.3 , pp. 6
    • Vijitruth, R.1    Liu, M.2    Choi, D.Y.3    Nguyen, X.V.4    Hunter, R.L.5    Bing, G.6
  • 38
    • 78650515554 scopus 로고    scopus 로고
    • Paraquat induces cyclooxygenase-2 (COX-2) implicated toxicity in human neuroblastoma SH-SY5Y cells
    • Yang W., Tiffany-Castiglioni E., Lee M.Y., Son I.H. Paraquat induces cyclooxygenase-2 (COX-2) implicated toxicity in human neuroblastoma SH-SY5Y cells. Toxicol Lett 2010, 199(3):239-246.
    • (2010) Toxicol Lett , vol.199 , Issue.3 , pp. 239-246
    • Yang, W.1    Tiffany-Castiglioni, E.2    Lee, M.Y.3    Son, I.H.4
  • 39
  • 40
    • 0036569812 scopus 로고    scopus 로고
    • Inhibition of COX-2 reduces the agedependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat
    • Casolini P., Catalani A., Zuena A.R., Angelucci L. Inhibition of COX-2 reduces the agedependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat. J Neurosci Res 2002, 68(3):337-343.
    • (2002) J Neurosci Res , vol.68 , Issue.3 , pp. 337-343
    • Casolini, P.1    Catalani, A.2    Zuena, A.R.3    Angelucci, L.4
  • 41
    • 33845985586 scopus 로고    scopus 로고
    • Aging stimulates cyclooxygenase-2 expression and prostaglandin E2 production in human periodontal ligament cells after the application of compressive force
    • Mayahara K., Kobayashi Y., Takimoto K., Suzuki N., Mitsui N., Shimizu N. Aging stimulates cyclooxygenase-2 expression and prostaglandin E2 production in human periodontal ligament cells after the application of compressive force. J Periodontal Res 2007, 42(1):8-14.
    • (2007) J Periodontal Res , vol.42 , Issue.1 , pp. 8-14
    • Mayahara, K.1    Kobayashi, Y.2    Takimoto, K.3    Suzuki, N.4    Mitsui, N.5    Shimizu, N.6
  • 42
    • 77953888505 scopus 로고    scopus 로고
    • Prolonged endochondral bone healing in senescence is shortened by low-intensity pulsed ultrasound in a manner dependent on COX-2
    • Naruse K., Sekiya H., Harada Y., Iwabuchi S., Kozai Y., Kawamata R., et al. Prolonged endochondral bone healing in senescence is shortened by low-intensity pulsed ultrasound in a manner dependent on COX-2. Ultrasound Med Biol 2010, 6(7):1098-1108.
    • (2010) Ultrasound Med Biol , vol.6 , Issue.7 , pp. 1098-1108
    • Naruse, K.1    Sekiya, H.2    Harada, Y.3    Iwabuchi, S.4    Kozai, Y.5    Kawamata, R.6
  • 43
    • 77956175899 scopus 로고    scopus 로고
    • Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NFκB nuclear localization
    • Seulgi Hur, Yun Sang Lee, Hyun Yoo, Jeong-Hee Yang, Tae-Yoon Kim Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NFκB nuclear localization. J Dermatol Sci 2010, 59:163-169.
    • (2010) J Dermatol Sci , vol.59 , pp. 163-169
    • Seulgi, H.1    Yun Sang, L.2    Hyun, Y.3    Jeong-Hee, Y.4    Tae-Yoon, K.5
  • 44
    • 1642561702 scopus 로고    scopus 로고
    • Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney
    • Melk A., Schmidt B.M., Takeuchi O., Sawitzki B., Rayner D.C., Halloran P.F. Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney. Kidney Int 2004, 65(2):510-520.
    • (2004) Kidney Int , vol.65 , Issue.2 , pp. 510-520
    • Melk, A.1    Schmidt, B.M.2    Takeuchi, O.3    Sawitzki, B.4    Rayner, D.C.5    Halloran, P.F.6
  • 45
    • 59849103084 scopus 로고    scopus 로고
    • Hypertension and sex differences in the age-related renal changes when cyclooxygenase-2 activity is reduced during nephrogenesis
    • Sáez F., Reverte V., Salazar F., Castells M.T., Llinás M.T., Salazar F.J. Hypertension and sex differences in the age-related renal changes when cyclooxygenase-2 activity is reduced during nephrogenesis. Hypertension 2009, 53:331-337.
    • (2009) Hypertension , vol.53 , pp. 331-337
    • Sáez, F.1    Reverte, V.2    Salazar, F.3    Castells, M.T.4    Llinás, M.T.5    Salazar, F.J.6
  • 46
    • 12244305551 scopus 로고    scopus 로고
    • Cellular distribution and contribution of cyclooxygenase (COX)-2 to diabetogenesis in NOD mouse
    • Luo C., Kallajoki M., Gross R., Mulari M., Makinen M., Teros T., et al. Cellular distribution and contribution of cyclooxygenase (COX)-2 to diabetogenesis in NOD mouse. Cell Tissue Res 2002, 310(2):169-175.
    • (2002) Cell Tissue Res , vol.310 , Issue.2 , pp. 169-175
    • Luo, C.1    Kallajoki, M.2    Gross, R.3    Mulari, M.4    Makinen, M.5    Teros, T.6
  • 48
    • 85042594546 scopus 로고    scopus 로고
    • Effect of short term calorie restriction on pro-inflammatory NF-κB and AP-1 in aged rat kidney
    • Jung K.J., Lee E.K., Kim J.Y., Zou Y., Sung B., Heo H.S., et al. Effect of short term calorie restriction on pro-inflammatory NF-κB and AP-1 in aged rat kidney. Inflamm Res 2009, 58(3):143-150.
    • (2009) Inflamm Res , vol.58 , Issue.3 , pp. 143-150
    • Jung, K.J.1    Lee, E.K.2    Kim, J.Y.3    Zou, Y.4    Sung, B.5    Heo, H.S.6
  • 49
    • 0041320694 scopus 로고    scopus 로고
    • Localization of COX-2 in the male reproductive tract during sexual maturation
    • Stanfield K.M., Khan K.N. Localization of COX-2 in the male reproductive tract during sexual maturation. Inflammopharmacol 2003, 11(3):259-266.
    • (2003) Inflammopharmacol , vol.11 , Issue.3 , pp. 259-266
    • Stanfield, K.M.1    Khan, K.N.2
  • 50
    • 0347139510 scopus 로고    scopus 로고
    • Constant expression of cyclooxygenase-2 gene in prostate and the lower urinary tract of estrogen-treated male rats. Zeitschrift Fur Naturforschung -C J
    • Luo C., Strauss L., Streng T., Ristimaki A., Santti R. Constant expression of cyclooxygenase-2 gene in prostate and the lower urinary tract of estrogen-treated male rats. Zeitschrift Fur Naturforschung -C J. Biosciences 2001, 56(5-6):455-463.
    • (2001) Biosciences , vol.56 , Issue.5-6 , pp. 455-463
    • Luo, C.1    Strauss, L.2    Streng, T.3    Ristimaki, A.4    Santti, R.5
  • 51
    • 67349102250 scopus 로고    scopus 로고
    • P53 and ATF-2 partly mediate the overexpression of COX-2 in H2O2-induced premature senescence of human fibroblasts
    • Zdanov S., Toussaint O., Debacq-Chainiaux F. P53 and ATF-2 partly mediate the overexpression of COX-2 in H2O2-induced premature senescence of human fibroblasts. Biogerontology 2009, 10(3):291-298.
    • (2009) Biogerontology , vol.10 , Issue.3 , pp. 291-298
    • Zdanov, S.1    Toussaint, O.2    Debacq-Chainiaux, F.3
  • 53
    • 21144456105 scopus 로고    scopus 로고
    • Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury
    • Mochizuki M., Ishii Y., Itoh K., Iizuka T., Morishima Y., Kimura T., et al. Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. Am J Respir Crit Care Med 2005, 171(11):1260-1266.
    • (2005) Am J Respir Crit Care Med , vol.171 , Issue.11 , pp. 1260-1266
    • Mochizuki, M.1    Ishii, Y.2    Itoh, K.3    Iizuka, T.4    Morishima, Y.5    Kimura, T.6
  • 54
    • 79952579536 scopus 로고    scopus 로고
    • Gene expression profiles of non-small cell lung cancer: survival prediction and new biomarkers
    • Välk K., Vooder T., Kolde R., Reintam M.A., Petzold C., Vilo J., et al. Gene expression profiles of non-small cell lung cancer: survival prediction and new biomarkers. Oncology 2010, 79(3-4):283-292.
    • (2010) Oncology , vol.79 , Issue.3-4 , pp. 283-292
    • Välk, K.1    Vooder, T.2    Kolde, R.3    Reintam, M.A.4    Petzold, C.5    Vilo, J.6


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