A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model

International Journal of Pharmaceutics

Volumn 207, Issue 1-2, 2000, Pages 21-30

  Meaney, C M ^a   O'Driscoll, C M ^b  

^a OctoPlus NV   (Netherlands)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

CaCo 2; Linoleic acid; Micellar systems; Permeability enhancement; Sodium cholate; Sodium taurocholate

Indexed keywords

BILE SALT; CHOLIC ACID; FATTY ACID; LINOLEIC ACID; MACROGOL 4000; MACROGOL 900; MACROGOL DERIVATIVE; MANNITOL; MARKER; PENETRATION ENHANCING AGENT; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL STRAIN CACO 2; CONJUGATION; CONTROLLED STUDY; DRUG MIXTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROPHILICITY; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; MICELLE; MODEL; NITROBLUE TETRAZOLIUM TEST; PRIORITY JOURNAL; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; COMPARATIVE STUDY; ELECTRIC IMPEDANCE; HUMAN; LINOLEIC ACID; MICELLES; MICROSCOPY, ELECTRON; PERMEABILITY; SUPPORT, NON-U.S. GOV'T;

EID: 0034633851     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00526-3     Document Type: Article

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