Double asymmetric induction as a mechanistic probe: The doubly diastereoselective conjugate addition of enantiopure lithium amides to enantiopure α,β-unsaturated esters and enantiopure α,β-unsaturated hydroxamates

Tetrahedron

Volumn 67, Issue 34, 2011, Pages 6382-6403

  Davies, Stephen G ^a   Lee, James A ^a   Roberts, Paul M ^a   Thomson, James E ^a   Yin, Jingda ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Chiral auxiliary; Conjugate addition; Doubly diastereoselective; Lithium amide

Indexed keywords

8 PHENYLMENTHYL ALPHA BETA UNSATURATED ESTER; 8 PHENYLMENTHYL CINNAMATE; 8 PHENYLMENTHYL CROTONATE; CINNAMIC ACID DERIVATIVE; CROTONIC ACID DERIVATIVE; ESTER DERIVATIVE; LITHIUM DERIVATIVE; LITHIUM N BENZYL N (ALPHA METHYL BENZYL)AMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CHIRALITY; CONFORMATION; CONJUGATE; DIASTEREOSELECTIVITY; DOUBLE ASYMMETRIC INDUCTION; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 79960569714     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.05.102     Document Type: Article

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