Alkylation and aldol reactions of acyl derivatives of N-1-(1′-naphthyl)ethyl-O-tert-butylhydroxylamine: asymmetric synthesis of α-alkoxy-, α-substituted-β-alkoxy- and α,β-dialkoxyaldehydes

Tetrahedron

Volumn 66, Issue 23, 2010, Pages 4167-4194

  Chernega, Alexander N ^a   Davies, Stephen G ^a   Fletcher, Ai M ^a   Goodwin, Christopher J ^b   Hepworth, David ^a   Prasad, R Shyam ^a   Roberts, Paul M ^a   Savory, Edward D ^a   Smith, Andrew D ^a   Thomson, James E ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Aldol reaction; Diastereoselective alkylation; Glycolate enolate; Weinreb amide

Indexed keywords

ALDEHYDE DERIVATIVE; CROWN COMPOUND; GLYCOLIC ACID DERIVATIVE; HALIDE; HYDROXYLAMINE; POTASSIUM DERIVATIVE;

ADDITION REACTION; ALDOL REACTION; ALKYLATION; ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; DIASTEREOISOMER; ENANTIOMER; PRIORITY JOURNAL; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 77953121509     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2010.03.105     Document Type: Article

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