-
1
-
-
70349964351
-
Can Web 2.0 reboot clinical trials?
-
Allison M. Can Web 2.0 reboot clinical trials?. Nat Biotech 2009, 27(10):895-902.
-
(2009)
Nat Biotech
, vol.27
, Issue.10
, pp. 895-902
-
-
Allison, M.1
-
2
-
-
71149101902
-
-
Patientslikeme: consumer health vocabulary as a folksonomy. In: AMIA annual symposium proceedings.
-
Smith CA, Wicks PJ. Patientslikeme: consumer health vocabulary as a folksonomy. In: AMIA annual symposium proceedings; 2008.
-
(2008)
-
-
Smith, C.A.1
Wicks, P.J.2
-
3
-
-
61449109247
-
Emerging patient-driven health care models: an examination of health social networks. Consumer personalized medicine and quantified self-tracking
-
Swan M. Emerging patient-driven health care models: an examination of health social networks. Consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009, 6(2):492-525.
-
(2009)
Int J Environ Res Public Health
, vol.6
, Issue.2
, pp. 492-525
-
-
Swan, M.1
-
4
-
-
74549151096
-
-
A hypbrid method to discover and rank cross-disciplinary associations. In: IEEE international conference on bioinformatics and biomedicine. Washigton (DC, USA).
-
Webster YW, Gudivada RC, Dow ER, et al. A hypbrid method to discover and rank cross-disciplinary associations. In: IEEE international conference on bioinformatics and biomedicine. Washigton (DC, USA); 2009.
-
(2009)
-
-
Webster, Y.W.1
Gudivada, R.C.2
Dow, E.R.3
-
5
-
-
48249103483
-
Networking metabolites and diseases
-
Braun P., Rietman E., Vidal M. Networking metabolites and diseases. Proc Nat Acad Sci 2008, 105(29):9849-9850.
-
(2008)
Proc Nat Acad Sci
, vol.105
, Issue.29
, pp. 9849-9850
-
-
Braun, P.1
Rietman, E.2
Vidal, M.3
-
6
-
-
54249155522
-
Network pharmacology
-
Hopkins A.L. Network pharmacology. Nat Chem Biol 2007, 4(11):682-690.
-
(2007)
Nat Chem Biol
, vol.4
, Issue.11
, pp. 682-690
-
-
Hopkins, A.L.1
-
7
-
-
41949118715
-
Network properties of genes harbouring inherited disease mutations
-
Feldman I., Rzhetsky A., Vitkup D. Network properties of genes harbouring inherited disease mutations. Proc Nat Acad Sci 2008, 105(11):4323-4328.
-
(2008)
Proc Nat Acad Sci
, vol.105
, Issue.11
, pp. 4323-4328
-
-
Feldman, I.1
Rzhetsky, A.2
Vitkup, D.3
-
8
-
-
35148838537
-
Drug-target network
-
Yildirim M.A., Goh K.I., Cusick M.E., et al. Drug-target network. Nat Biotechnol 2007, 25(10):1119-1126.
-
(2007)
Nat Biotechnol
, vol.25
, Issue.10
, pp. 1119-1126
-
-
Yildirim, M.A.1
Goh, K.I.2
Cusick, M.E.3
-
9
-
-
34250777249
-
Network analysis of FDA approved drugs and their targets
-
Ma'ayan A., Jenkins S.L., Goldfarb J., et al. Network analysis of FDA approved drugs and their targets. Mt Sinai J Med 2007, 74(1):27-32.
-
(2007)
Mt Sinai J Med
, vol.74
, Issue.1
, pp. 27-32
-
-
Ma'ayan, A.1
Jenkins, S.L.2
Goldfarb, J.3
-
10
-
-
33947095027
-
A human phenome-interactome network of protein complexes implicated in genetic disorders
-
Lage K., Karlberg E.O., Storling Z.M., et al. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 2007, 25(3):309.
-
(2007)
Nat Biotechnol
, vol.25
, Issue.3
, pp. 309
-
-
Lage, K.1
Karlberg, E.O.2
Storling, Z.M.3
-
11
-
-
33751017706
-
Discovering disease-genes by topological features in human protein-protein interaction network
-
Xu J., Li Y. Discovering disease-genes by topological features in human protein-protein interaction network. Bioinformatics 2006, 22(22):2800-2805.
-
(2006)
Bioinformatics
, vol.22
, Issue.22
, pp. 2800-2805
-
-
Xu, J.1
Li, Y.2
-
12
-
-
48249158278
-
The implications of human metabolic network topology for disease comorbidity
-
Lee D.S., Park J., Kay K.A., et al. The implications of human metabolic network topology for disease comorbidity. Proc Nat Acad Sci 2008, 105(29):9880-9885.
-
(2008)
Proc Nat Acad Sci
, vol.105
, Issue.29
, pp. 9880-9885
-
-
Lee, D.S.1
Park, J.2
Kay, K.A.3
-
13
-
-
38349164409
-
Computing topological parameters of biological networks
-
Assenov Y., Ramirez F., Schelhorn S.E., et al. Computing topological parameters of biological networks. Bioinformatics 2008, 24(2):282-284.
-
(2008)
Bioinformatics
, vol.24
, Issue.2
, pp. 282-284
-
-
Assenov, Y.1
Ramirez, F.2
Schelhorn, S.E.3
-
14
-
-
63549097414
-
Semantic web for integrated network analysis in biomedicine
-
Chen H., Ding L., Wu Z., et al. Semantic web for integrated network analysis in biomedicine. Brief Bioinfor 2009, 10(2):177-192.
-
(2009)
Brief Bioinfor
, vol.10
, Issue.2
, pp. 177-192
-
-
Chen, H.1
Ding, L.2
Wu, Z.3
-
15
-
-
46449111382
-
Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network
-
Iossifov I., Zheng T., Baron M., et al. Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network. Genome Res 2008, 18(7):1150-1162.
-
(2008)
Genome Res
, vol.18
, Issue.7
, pp. 1150-1162
-
-
Iossifov, I.1
Zheng, T.2
Baron, M.3
-
16
-
-
79960556406
-
-
Finding and ranking knowledge on the semantic web. In: 4th International semantic web conference. Galway, Ireland.
-
Ding L, Pan R, Finin T, et al., Finding and ranking knowledge on the semantic web. In: 4th International semantic web conference. Galway, Ireland; 2005.
-
(2005)
-
-
Ding, L.1
Pan, R.2
Finin, T.3
-
17
-
-
62849126285
-
Disease candidate gene identification and prioritization using protein interaction networks
-
Chen J., Aronow B., Jegga A. Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinfor 2009, 10(73):1-2.
-
(2009)
BMC Bioinfor
, vol.10
, Issue.73
, pp. 1-2
-
-
Chen, J.1
Aronow, B.2
Jegga, A.3
-
18
-
-
79960565794
-
-
Ontology ranking based on the analysis of concept structures. In: Proceedings of the 3rd international conference on knowledge capture. Banff, Canada.
-
Harith A, Christopher B. Ontology ranking based on the analysis of concept structures. In: Proceedings of the 3rd international conference on knowledge capture. Banff, Canada; 2005.
-
(2005)
-
-
Harith, A.1
Christopher, B.2
-
19
-
-
70350664654
-
Analyzing biological network parameters with centiscape
-
Scardoni G., Laudanna C. Analyzing biological network parameters with centiscape. Bioinformatics 2009, 25(21):2857-2859.
-
(2009)
Bioinformatics
, vol.25
, Issue.21
, pp. 2857-2859
-
-
Scardoni, G.1
Laudanna, C.2
-
20
-
-
77952376110
-
-
Algorithms for estimating relative importance in networks. In: Proceedings of the ninth ACM SIGKDD international conference on knowledge discovery and data mining. Washington (DC, USA).
-
White S, Smyth P. Algorithms for estimating relative importance in networks. In: Proceedings of the ninth ACM SIGKDD international conference on knowledge discovery and data mining. Washington (DC, USA); 2003.
-
(2003)
-
-
White, S.1
Smyth, P.2
-
21
-
-
0032256758
-
-
Authoritative sources in a hyperlinked environment. In: Proceedings of the ninth ACM-SIAM symposium on discrete algorithms. San Francisco (USA); 1998.
-
Kleinberg JM. Authoritative sources in a hyperlinked environment. In: Proceedings of the ninth ACM-SIAM symposium on discrete algorithms. San Francisco (USA); 1998.
-
(1998)
-
-
Kleinberg, J.M.1
-
22
-
-
52949136965
-
Identifying disease-causal genes using semantic web-based representation of integrated genomic and phenomic knowledge
-
Gudivada R.C., Qu X.A., Chen J., et al. Identifying disease-causal genes using semantic web-based representation of integrated genomic and phenomic knowledge. J Biomed Infor 2008, 41(5):717-729.
-
(2008)
J Biomed Infor
, vol.41
, Issue.5
, pp. 717-729
-
-
Gudivada, R.C.1
Qu, X.A.2
Chen, J.3
-
23
-
-
74549151096
-
-
A hybrid method to discover and rank cross-domain associations. In: IEEE international conference on bioinformatics and biomedicine. Washington (DC).
-
Webster Y, Gudivada R, Dow E, et al. A hybrid method to discover and rank cross-domain associations. In: IEEE international conference on bioinformatics and biomedicine. Washington (DC); 2009.
-
(2009)
-
-
Webster, Y.1
Gudivada, R.2
Dow, E.3
-
24
-
-
84856314325
-
-
Patientslikeme, [accessed January 2009].
-
Patientslikeme, [accessed January 2009]. http://www.Patientslikeme.Com/Als/Symptoms.
-
-
-
-
25
-
-
0345863927
-
The unified medical language system (UMLS): integrating biomedical terminology
-
Bodenreider O. The unified medical language system (UMLS): integrating biomedical terminology. Nucl Acids Res 2004, 32:267.
-
(2004)
Nucl Acids Res
, vol.32
, pp. 267
-
-
Bodenreider, O.1
-
26
-
-
0035752429
-
-
Effective mapping of biomedical text to the UMLS metathesaurus: the metamap program. In: Proc AMIA Symp.
-
Aronson AR. Effective mapping of biomedical text to the UMLS metathesaurus: the metamap program. In: Proc AMIA Symp; 2001. p. 17.
-
(2001)
, pp. 17
-
-
Aronson, A.R.1
-
27
-
-
84856311602
-
-
Patientslikeme. [accessed January 2009].
-
Patientslikeme. [accessed January 2009]. http://Www.Patientslikeme.Com/Als/Treatments.
-
-
-
-
28
-
-
70449387056
-
A dictionary to identify small molecules and drugs in free text
-
Hettne K.M., Stierum R.H., Schuemie M.J., et al. A dictionary to identify small molecules and drugs in free text. Bioinformatics 2009, 535.
-
(2009)
Bioinformatics
, pp. 535
-
-
Hettne, K.M.1
Stierum, R.H.2
Schuemie, M.J.3
-
29
-
-
62849126285
-
Disease candidate gene identification and prioritization using protein interaction networks
-
Chen J., Aronow B., Jegga A. Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinfor 2009, 10(1):73.
-
(2009)
BMC Bioinfor
, vol.10
, Issue.1
, pp. 73
-
-
Chen, J.1
Aronow, B.2
Jegga, A.3
-
30
-
-
33846056133
-
Folate and neural tube defects
-
Pitkin R.M. Folate and neural tube defects. Am J Clin Nutr 2007, 85(1):285-288.
-
(2007)
Am J Clin Nutr
, vol.85
, Issue.1
, pp. 285-288
-
-
Pitkin, R.M.1
-
31
-
-
34247218125
-
Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population
-
Ray J.G., Wyatt P.R., Thompson M.D., et al. Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population. Epidemiology 2007, 18(3):362-366.
-
(2007)
Epidemiology
, vol.18
, Issue.3
, pp. 362-366
-
-
Ray, J.G.1
Wyatt, P.R.2
Thompson, M.D.3
-
32
-
-
55849091713
-
Risk of colorectal cancer associated with the C677t polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients
-
Guerreiro C.S., Carmona B., Goncalves S., et al. Risk of colorectal cancer associated with the C677t polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients. Am J Clin Nutr 2008, 88(5):1413-1418.
-
(2008)
Am J Clin Nutr
, vol.88
, Issue.5
, pp. 1413-1418
-
-
Guerreiro, C.S.1
Carmona, B.2
Goncalves, S.3
-
33
-
-
0032713838
-
Folic acid deficiency and cancer: mechanisms of DNA instability
-
Duthie S.J. Folic acid deficiency and cancer: mechanisms of DNA instability. Brit Med Bull 1999, 55(3):578-592.
-
(1999)
Brit Med Bull
, vol.55
, Issue.3
, pp. 578-592
-
-
Duthie, S.J.1
-
34
-
-
71049166754
-
The evidence for altered RNA metabolism in amyotrophic lateral sclerosis (ALS)
-
Strong M.J. The evidence for altered RNA metabolism in amyotrophic lateral sclerosis (ALS). J Neurol Sci 2010, 288(1-2):11-12.
-
(2010)
J Neurol Sci
, vol.288
, Issue.1-2
, pp. 11-12
-
-
Strong, M.J.1
-
36
-
-
0036156999
-
Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosis
-
Corcia P., Mayeux-Portas V., Khoris J., et al. Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosis. Ann Neurol 2002, 51(2):243-246.
-
(2002)
Ann Neurol
, vol.51
, Issue.2
, pp. 243-246
-
-
Corcia, P.1
Mayeux-Portas, V.2
Khoris, J.3
-
37
-
-
0035885774
-
Association of APOE 4 allele with survival in amyotrophic lateral sclerosis
-
Drory V.E., Birnbaum M., Korczyn A.D., et al. Association of APOE 4 allele with survival in amyotrophic lateral sclerosis. J Neurol Sci 2001, 190(1-2):17-20.
-
(2001)
J Neurol Sci
, vol.190
, Issue.1-2
, pp. 17-20
-
-
Drory, V.E.1
Birnbaum, M.2
Korczyn, A.D.3
-
38
-
-
25444501340
-
Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS
-
Goodall E.F., Greenway M.J., Van Marion I., et al. Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS. Neurology 2005, 65(6):934-937.
-
(2005)
Neurology
, vol.65
, Issue.6
, pp. 934-937
-
-
Goodall, E.F.1
Greenway, M.J.2
Van Marion, I.3
-
39
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
Hadano S., Hand C., Osuga H. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. Nat Genet 2001, 29:166-173.
-
(2001)
Nat Genet
, vol.29
, pp. 166-173
-
-
Hadano, S.1
Hand, C.2
Osuga, H.3
-
40
-
-
37549062995
-
Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis
-
Van Es M.A., Van Vught P.W.J., Blauw H.M., et al. Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. Nat Genet 2008, 40(1):29-31.
-
(2008)
Nat Genet
, vol.40
, Issue.1
, pp. 29-31
-
-
Van Es, M.A.1
Van Vught, P.W.J.2
Blauw, H.M.3
-
41
-
-
39749119374
-
A genome-wide association study of sporadic ALS in a homogenous Irish population
-
Cronin S., Berger S., Ding J., et al. A genome-wide association study of sporadic ALS in a homogenous Irish population. Hum Mol Genet 2008, 17(5):768-774.
-
(2008)
Hum Mol Genet
, vol.17
, Issue.5
, pp. 768-774
-
-
Cronin, S.1
Berger, S.2
Ding, J.3
-
42
-
-
33847622526
-
Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data
-
Schymick J.C., Scholz S.W., Fung H.-C., et al. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol 2007, 6(4):322-328.
-
(2007)
Lancet Neurol
, vol.6
, Issue.4
, pp. 322-328
-
-
Schymick, J.C.1
Scholz, S.W.2
Fung, H.-C.3
-
43
-
-
0035957312
-
Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS
-
Veldink J.H., Van Den Berg L.H., Cobben J.M., et al. Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS. Neurology 2001, 56(6):749-752.
-
(2001)
Neurology
, vol.56
, Issue.6
, pp. 749-752
-
-
Veldink, J.H.1
Van Den Berg, L.H.2
Cobben, J.M.3
-
44
-
-
34548646702
-
ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study
-
Van Es M.A., Van Vught P.W., Blauw H.M., et al. ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Lancet Neurol 2007, 6(10):869-877.
-
(2007)
Lancet Neurol
, vol.6
, Issue.10
, pp. 869-877
-
-
Van Es, M.A.1
Van Vught, P.W.2
Blauw, H.M.3
-
45
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D., Siddique T., Patterson D. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362:59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.1
Siddique, T.2
Patterson, D.3
-
46
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski T.J., Bosco D.A., Leclerc A.L., et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009, 323(5918):1205-1208.
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1205-1208
-
-
Kwiatkowski, T.J.1
Bosco, D.A.2
Leclerc, A.L.3
-
47
-
-
4143084861
-
Point mutations of the P150 subunit of dynactin (DCTN1) gene in ALS
-
Munch C., Sedlmeier R., Meyer T., et al. Point mutations of the P150 subunit of dynactin (DCTN1) gene in ALS. Neurology 2004, 63(4):724-726.
-
(2004)
Neurology
, vol.63
, Issue.4
, pp. 724-726
-
-
Munch, C.1
Sedlmeier, R.2
Meyer, T.3
-
48
-
-
0036896519
-
The relationship of SMN to amyotrophic lateral sclerosis
-
Crawford T.O., Skolasky R.L. The relationship of SMN to amyotrophic lateral sclerosis. Ann Neurol 2002, 52(6):857-858.
-
(2002)
Ann Neurol
, vol.52
, Issue.6
, pp. 857-858
-
-
Crawford, T.O.1
Skolasky, R.L.2
-
49
-
-
0041903805
-
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
-
Lambrechts D., Storkebaum E., Morimoto M., et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 2003, 34(4):383-394.
-
(2003)
Nat Genet
, vol.34
, Issue.4
, pp. 383-394
-
-
Lambrechts, D.1
Storkebaum, E.2
Morimoto, M.3
-
50
-
-
52649149895
-
Riluzole in psychiatry: a systematic review of the literature
-
Zarate C.A., Manji H.K. Riluzole in psychiatry: a systematic review of the literature. Exp Opin Drug Metab Toxicol 2008, 4(9):1223-1234.
-
(2008)
Exp Opin Drug Metab Toxicol
, vol.4
, Issue.9
, pp. 1223-1234
-
-
Zarate, C.A.1
Manji, H.K.2
-
51
-
-
33947367306
-
Aberrant synaptic activation of N-methyl-d-aspartate receptors underlies ethanol withdrawal hyperexcitability
-
Hendricson A.W., Maldve R.E., Salinas A.G., et al. Aberrant synaptic activation of N-methyl-d-aspartate receptors underlies ethanol withdrawal hyperexcitability. J Pharmacol Exp Therap 2007, 321(1):60-72.
-
(2007)
J Pharmacol Exp Therap
, vol.321
, Issue.1
, pp. 60-72
-
-
Hendricson, A.W.1
Maldve, R.E.2
Salinas, A.G.3
-
52
-
-
68149108465
-
Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms
-
Besheer J., Lepoutre V., Hodge C.W. Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms. Alcohol: Clin Exp Res 2009, 33(8):1460-1468.
-
(2009)
Alcohol: Clin Exp Res
, vol.33
, Issue.8
, pp. 1460-1468
-
-
Besheer, J.1
Lepoutre, V.2
Hodge, C.W.3
-
53
-
-
33847196843
-
A comparative evaluation of full-text, concept-based, and context-sensitive search
-
Moskovitch R. A comparative evaluation of full-text, concept-based, and context-sensitive search. J Am Med Inform Assoc 2007, 14(2):164-174.
-
(2007)
J Am Med Inform Assoc
, vol.14
, Issue.2
, pp. 164-174
-
-
Moskovitch, R.1
-
54
-
-
79960556009
-
-
Utilizing resource importance for ranking semantic web query results in semantic web and databases. In: Proceedings of the Workshop on Semantic Web and Databases. Berlin, Germany.
-
Bamba B, Mukherjea S. Utilizing resource importance for ranking semantic web query results in semantic web and databases. In: Proceedings of the Workshop on Semantic Web and Databases. Berlin, Germany; 2003.
-
(2003)
-
-
Bamba, B.1
Mukherjea, S.2
|