-
1
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
Cleveland D., and Rothstein J. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2 (2001) 806-819
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 806-819
-
-
Cleveland, D.1
Rothstein, J.2
-
2
-
-
34250209501
-
Amyotrophic lateral sclerosis
-
Mitchell J., and Borasio G. Amyotrophic lateral sclerosis. Lancet 369 (2007) 2031-2041
-
(2007)
Lancet
, vol.369
, pp. 2031-2041
-
-
Mitchell, J.1
Borasio, G.2
-
3
-
-
0035978743
-
Amyotrophic lateral sclerosis
-
Rowland L., and Shneider N. Amyotrophic lateral sclerosis. N Engl J Med 344 (2001) 1688-1700
-
(2001)
N Engl J Med
, vol.344
, pp. 1688-1700
-
-
Rowland, L.1
Shneider, N.2
-
4
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II
-
Lacomblez L., Bensimon G., Leigh P., Guillet P., and Meininger V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II. Lancet 347 (1996) 1425-1431
-
(1996)
Lancet
, vol.347
, pp. 1425-1431
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.3
Guillet, P.4
Meininger, V.5
-
5
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D., Siddique T., Patterson D., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 (1993) 59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.1
Siddique, T.2
Patterson, D.3
-
6
-
-
33645422711
-
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis
-
Greenway M., Andersen P., Russ C., et al. ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Nat Genet 38 (2006) 411-413
-
(2006)
Nat Genet
, vol.38
, pp. 411-413
-
-
Greenway, M.1
Andersen, P.2
Russ, C.3
-
7
-
-
6344257200
-
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
Nishimura A., Mitne-Neto M., Silva H., et al. A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet 75 (2004) 822-831
-
(2004)
Am J Hum Genet
, vol.75
, pp. 822-831
-
-
Nishimura, A.1
Mitne-Neto, M.2
Silva, H.3
-
8
-
-
33847674460
-
The complex genetics of amyotrophic lateral sclerosis
-
Hardiman O., and Greenway M. The complex genetics of amyotrophic lateral sclerosis. Lancet Neurol 6 (2007) 291-292
-
(2007)
Lancet Neurol
, vol.6
, pp. 291-292
-
-
Hardiman, O.1
Greenway, M.2
-
9
-
-
33751120678
-
Amyotrophic lateral sclerosis as a complex genetic disease
-
Simpson C., and Al-Chalabi A. Amyotrophic lateral sclerosis as a complex genetic disease. Biochim Biophys Acta 1762 (2006) 973-985
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 973-985
-
-
Simpson, C.1
Al-Chalabi, A.2
-
10
-
-
16544377783
-
The future of motor neuron disease: the challenge is in the genes
-
Veldink J., Van den Berg L., and Wokke J. The future of motor neuron disease: the challenge is in the genes. J Neurol 251 (2004) 491-500
-
(2004)
J Neurol
, vol.251
, pp. 491-500
-
-
Veldink, J.1
Van den Berg, L.2
Wokke, J.3
-
12
-
-
0034864628
-
Apoptosis in amyotrophic lateral sclerosis: a review of the evidence
-
Sathasivam S., Ince P., and Shaw P. Apoptosis in amyotrophic lateral sclerosis: a review of the evidence. Neuropathol Appl Neurobiol 27 (2001) 257-274
-
(2001)
Neuropathol Appl Neurobiol
, vol.27
, pp. 257-274
-
-
Sathasivam, S.1
Ince, P.2
Shaw, P.3
-
13
-
-
33751229311
-
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
-
Van Den Bosch L., Van Damme P., Bogaert E., and Robberecht W. The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis. Biochim Biophys Acta 1762 (2006) 1068-1082
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 1068-1082
-
-
Van Den Bosch, L.1
Van Damme, P.2
Bogaert, E.3
Robberecht, W.4
-
14
-
-
0034978562
-
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
-
Oosthuyse B., et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet 28 (2001) 131-138
-
(2001)
Nat Genet
, vol.28
, pp. 131-138
-
-
Oosthuyse, B.1
-
15
-
-
25444501340
-
Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS
-
Goodall E., Greenway M., van M., I, Carroll C., Hardiman O., and Morrison K. Association of the H63D polymorphism in the hemochromatosis gene with sporadic ALS. Neurology 65 (2005) 934-937
-
(2005)
Neurology
, vol.65
, pp. 934-937
-
-
Goodall, E.1
Greenway, M.2
van Marion, I.3
Carroll, C.4
Hardiman, O.5
Morrison, K.6
-
16
-
-
34548237450
-
Large-scale pathways-based association study in amyotrophic lateral sclerosis
-
Kasperaviciute D., Weale M., Shianna K., et al. Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain 130 (2007) 2292-2301
-
(2007)
Brain
, vol.130
, pp. 2292-2301
-
-
Kasperaviciute, D.1
Weale, M.2
Shianna, K.3
-
17
-
-
0041903805
-
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
-
Lambrechts D., Storkebaum E., Morimoto M., et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat Genet 34 (2003) 383-394
-
(2003)
Nat Genet
, vol.34
, pp. 383-394
-
-
Lambrechts, D.1
Storkebaum, E.2
Morimoto, M.3
-
18
-
-
33748707208
-
Paraoxonase cluster polymorphisms are associated with sporadic ALS
-
Saeed M., Siddique N., Hung W., et al. Paraoxonase cluster polymorphisms are associated with sporadic ALS. Neurology 67 (2006) 771-776
-
(2006)
Neurology
, vol.67
, pp. 771-776
-
-
Saeed, M.1
Siddique, N.2
Hung, W.3
-
19
-
-
33846115578
-
The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population
-
Sutedja N., Sinke R., Van Vught P., et al. The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population. Arch Neurol 64 (2007) 63-67
-
(2007)
Arch Neurol
, vol.64
, pp. 63-67
-
-
Sutedja, N.1
Sinke, R.2
Van Vught, P.3
-
20
-
-
25444493946
-
SMN genotypes producing less SMN protein increase susceptibility to and severity of sporadic ALS
-
Veldink J., Kalmijn S., Van der Hout A., et al. SMN genotypes producing less SMN protein increase susceptibility to and severity of sporadic ALS. Neurology 65 (2005) 820-825
-
(2005)
Neurology
, vol.65
, pp. 820-825
-
-
Veldink, J.1
Kalmijn, S.2
Van der Hout, A.3
-
21
-
-
26944437969
-
Genetic epidemiology and public health: hope, hype, and future prospects
-
Davey S., Ebrahim S., Lewis S., Hansell A., Palmer L., and Burton P. Genetic epidemiology and public health: hope, hype, and future prospects. Lancet 366 (2005) 1484-1498
-
(2005)
Lancet
, vol.366
, pp. 1484-1498
-
-
Davey, S.1
Ebrahim, S.2
Lewis, S.3
Hansell, A.4
Palmer, L.5
Burton, P.6
-
22
-
-
25144501575
-
Genetic association studies
-
Cordell H., and Clayton D. Genetic association studies. Lancet 366 (2005) 1121-1131
-
(2005)
Lancet
, vol.366
, pp. 1121-1131
-
-
Cordell, H.1
Clayton, D.2
-
23
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
The Welcome Trust Case Control Consortium
-
The Welcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447 (2007) 661-678
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
24
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton D., Pooley K., Dunning A., et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447 (2007) 1087-1093
-
(2007)
Nature
, vol.447
, pp. 1087-1093
-
-
Easton, D.1
Pooley, K.2
Dunning, A.3
-
25
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein R., Zeiss C., Chew E., et al. Complement factor H polymorphism in age-related macular degeneration. Science 308 (2005) 385-389
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.1
Zeiss, C.2
Chew, E.3
-
26
-
-
34347324029
-
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
-
van Heel D., Franke L., Hunt K., et al. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet 39 (2007) 827-829
-
(2007)
Nat Genet
, vol.39
, pp. 827-829
-
-
van Heel, D.1
Franke, L.2
Hunt, K.3
-
27
-
-
79959503826
-
The International HapMap Project
-
The International HapMap Consortium
-
The International HapMap Consortium. The International HapMap Project. Nature 426 (2003) 789-796
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
28
-
-
23344448837
-
Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease
-
Borovecki F., Lovrecic L., Zhou J., et al. Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. Proc Natl Acad Sci U S A 102 (2005) 11023-11028
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 11023-11028
-
-
Borovecki, F.1
Lovrecic, L.2
Zhou, J.3
-
29
-
-
0035205029
-
Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease
-
Tang Y., Lu A., Aronow B., and Sharp F. Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease. Ann Neurol 50 (2001) 699-707
-
(2001)
Ann Neurol
, vol.50
, pp. 699-707
-
-
Tang, Y.1
Lu, A.2
Aronow, B.3
Sharp, F.4
-
30
-
-
35148814074
-
Transcriptional profiling of Alzheimer blood mononuclear cells by microarray
-
published online Sept 18. DOI:10.1016/j.neurobiolaging.2006.08.004
-
Maes O., Xu S., Yu B., Chertkow H., Wang E., and Schipper H. Transcriptional profiling of Alzheimer blood mononuclear cells by microarray. Neurobiol Aging (2006). published online Sept 18. DOI:10.1016/j.neurobiolaging.2006.08.004
-
(2006)
Neurobiol Aging
-
-
Maes, O.1
Xu, S.2
Yu, B.3
Chertkow, H.4
Wang, E.5
Schipper, H.6
-
31
-
-
33846465545
-
Molecular markers of early Parkinson's disease based on gene expression in blood
-
Scherzer C., Eklund A., Morse L., et al. Molecular markers of early Parkinson's disease based on gene expression in blood. Proc Natl Acad Sci U S A 104 (2007) 955-960
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 955-960
-
-
Scherzer, C.1
Eklund, A.2
Morse, L.3
-
32
-
-
0028142392
-
El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis
-
Brooks B. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. J Neurol Sci 124 suppl (1994) 96-107
-
(1994)
J Neurol Sci
, vol.124
, Issue.SUPPL
, pp. 96-107
-
-
Brooks, B.1
-
33
-
-
0035975995
-
The applications of capture-recapture models to epidemiological data
-
Chao A., Tsay P., Lin S., Shau W., and Chao D. The applications of capture-recapture models to epidemiological data. Stat Med 20 (2001) 3123-3157
-
(2001)
Stat Med
, vol.20
, pp. 3123-3157
-
-
Chao, A.1
Tsay, P.2
Lin, S.3
Shau, W.4
Chao, D.5
-
34
-
-
0026559016
-
Capture-recapture methods
-
Hook E., and Regal R. Capture-recapture methods. Lancet 339 (1992) 742
-
(1992)
Lancet
, vol.339
, pp. 742
-
-
Hook, E.1
Regal, R.2
-
35
-
-
33745475088
-
A two-stage design for multiple testing in large-scale association studies
-
Wen S., Tzeng J., Kao J., and Hsiao C. A two-stage design for multiple testing in large-scale association studies. J Hum Genet 51 (2006) 523-532
-
(2006)
J Hum Genet
, vol.51
, pp. 523-532
-
-
Wen, S.1
Tzeng, J.2
Kao, J.3
Hsiao, C.4
-
36
-
-
34147123804
-
Ethnic variation in the incidence of ALS: a systematic review
-
Cronin S., Hardiman O., and Traynor B. Ethnic variation in the incidence of ALS: a systematic review. Neurology 68 (2007) 1002-1007
-
(2007)
Neurology
, vol.68
, pp. 1002-1007
-
-
Cronin, S.1
Hardiman, O.2
Traynor, B.3
-
37
-
-
34548292504
-
PLINK: a toolset for whole-genome association and population based linkage analysis
-
Purcell S., Neale B., Todd-Brown K., et al. PLINK: a toolset for whole-genome association and population based linkage analysis. Am J Hum Genet 81 (2007) 559-575
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
-
38
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price A., Patterson N., Plenge R., Weinblatt M., Shadick N., and Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38 (2006) 904-909
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.1
Patterson, N.2
Plenge, R.3
Weinblatt, M.4
Shadick, N.5
Reich, D.6
-
39
-
-
28044435808
-
Lack of association between VEGF polymorphisms and ALS in a Dutch population
-
Van Vught P., Sutedja N., Veldink J., et al. Lack of association between VEGF polymorphisms and ALS in a Dutch population. Neurology 65 (2005) 1643-1645
-
(2005)
Neurology
, vol.65
, pp. 1643-1645
-
-
Van Vught, P.1
Sutedja, N.2
Veldink, J.3
-
40
-
-
33847622526
-
Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data
-
Schymick J., Scholz S., Fung H., et al. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol 6 (2007) 322-328
-
(2007)
Lancet Neurol
, vol.6
, pp. 322-328
-
-
Schymick, J.1
Scholz, S.2
Fung, H.3
-
41
-
-
34548083742
-
Whole-genome analysis of sporadic amyotrophic lateral sclerosis
-
published online Aug 1. DOI:10.1056/NEJMoa070174
-
Dunckley T., Huentelman M., Craig D., et al. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. N Engl J Med (2007). published online Aug 1. DOI:10.1056/NEJMoa070174
-
(2007)
N Engl J Med
-
-
Dunckley, T.1
Huentelman, M.2
Craig, D.3
-
42
-
-
33745018838
-
Inositol 1,4,5-trisphosphate IP(3) receptors and their role in neuronal cell function
-
Mikoshiba K. Inositol 1,4,5-trisphosphate IP(3) receptors and their role in neuronal cell function. J Neurochem 97 (2006) 1627-1633
-
(2006)
J Neurochem
, vol.97
, pp. 1627-1633
-
-
Mikoshiba, K.1
-
43
-
-
0033520439
-
Calcium handling proteins in isolated spinal motoneurons
-
Van Den Bosch L., Verhoeven K., De Smedt H., Wuytack F., Missiaen L., and Robberecht W. Calcium handling proteins in isolated spinal motoneurons. Life Sci 65 (1999) 1597-1606
-
(1999)
Life Sci
, vol.65
, pp. 1597-1606
-
-
Van Den Bosch, L.1
Verhoeven, K.2
De Smedt, H.3
Wuytack, F.4
Missiaen, L.5
Robberecht, W.6
-
44
-
-
34249930943
-
The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork
-
Choe C., and Ehrlich B. The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork. Sci STKE 28 (2006) re15
-
(2006)
Sci STKE
, vol.28
-
-
Choe, C.1
Ehrlich, B.2
-
45
-
-
4544252174
-
Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate
-
Boehning D., Patterson R., and Snyder S. Apoptosis and calcium: new roles for cytochrome c and inositol 1,4,5-trisphosphate. Cell Cycle 3 (2004) 252-254
-
(2004)
Cell Cycle
, vol.3
, pp. 252-254
-
-
Boehning, D.1
Patterson, R.2
Snyder, S.3
-
46
-
-
1642495897
-
Intracellular calcium release is required for caspase-3 and -9 activation
-
Tantral L., Malathi K., Kohyama S., Silane M., Berenstein A., and Jayaraman T. Intracellular calcium release is required for caspase-3 and -9 activation. Cell Biochem Funct 22 (2004) 35-40
-
(2004)
Cell Biochem Funct
, vol.22
, pp. 35-40
-
-
Tantral, L.1
Malathi, K.2
Kohyama, S.3
Silane, M.4
Berenstein, A.5
Jayaraman, T.6
-
47
-
-
33845288349
-
Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis
-
Wozniak A., Wang X., Stieren E., Scarbrough S., Elferink C., and Boehning D. Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis. J Cell Biol 175 (2006) 709-714
-
(2006)
J Cell Biol
, vol.175
, pp. 709-714
-
-
Wozniak, A.1
Wang, X.2
Stieren, E.3
Scarbrough, S.4
Elferink, C.5
Boehning, D.6
-
48
-
-
0031283329
-
Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure
-
Gutstein D., and Marks A. Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure. Heart Vessels Suppl 12 (1997) 53-57
-
(1997)
Heart Vessels
, Issue.SUPPL. 12
, pp. 53-57
-
-
Gutstein, D.1
Marks, A.2
-
49
-
-
0028291592
-
Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors
-
Yamamoto-Hino M., Sugiyama T., Hikichi K., et al. Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors. Receptors Channels 2 (1994) 9-22
-
(1994)
Receptors Channels
, vol.2
, pp. 9-22
-
-
Yamamoto-Hino, M.1
Sugiyama, T.2
Hikichi, K.3
|