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Volumn 33, Issue 8, 2009, Pages 1460-1468

Preclinical evaluation of riluzole: Assessments of ethanol self-administration and ethanol withdrawal symptoms

Author keywords

Alcohol Drinking; Alcoholism; GABA; NMDA; PKC; Riluzole; Self Administration

Indexed keywords

ALCOHOL; RILUZOLE;

EID: 68149108465     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2009.00976.x     Document Type: Article
Times cited : (23)

References (73)
  • 1
    • 0034813626 scopus 로고    scopus 로고
    • Pharmacologic approaches to the management of alcoholism
    • Anton RF (2001) Pharmacologic approaches to the management of alcoholism. J Clin Psychiatry 62 (Suppl 20 11 17.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 20 , pp. 11-17
    • Anton, R.F.1
  • 2
    • 0037343764 scopus 로고    scopus 로고
    • Coregulation of ethanol discrimination by the nucleus accumbens and amygdala
    • Besheer J, Cox AA, Hodge CW (2003) Coregulation of ethanol discrimination by the nucleus accumbens and amygdala. Alcohol Clin Exp Res 27 : 450 456.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 450-456
    • Besheer, J.1    Cox, A.A.2    Hodge, C.W.3
  • 3
    • 3843118819 scopus 로고    scopus 로고
    • GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice
    • Besheer J, Lepoutre V, Hodge CW (2004) GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice. Psychopharmacology (Berl) 174 : 358 366.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 358-366
    • Besheer, J.1    Lepoutre, V.2    Hodge, C.W.3
  • 4
    • 33748624365 scopus 로고    scopus 로고
    • GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon
    • Besheer J, Lepoutre V, Mole B, Hodge CW (2006) GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon. Synapse 60 : 411 419.
    • (2006) Synapse , vol.60 , pp. 411-419
    • Besheer, J.1    Lepoutre, V.2    Mole, B.3    Hodge, C.W.4
  • 5
    • 0032787789 scopus 로고    scopus 로고
    • Effects of N-methyl-D-aspartate receptor antagonists on reinforced and nonreinforced responding for ethanol in rats
    • Bienkowski P, Koros E, Kostowski W, Danysz W (1999) Effects of N-methyl-D-aspartate receptor antagonists on reinforced and nonreinforced responding for ethanol in rats. Alcohol 18 : 131 137.
    • (1999) Alcohol , vol.18 , pp. 131-137
    • Bienkowski, P.1    Koros, E.2    Kostowski, W.3    Danysz, W.4
  • 6
    • 0035830652 scopus 로고    scopus 로고
    • Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat
    • Bienkowski P, Krzascik P, Koros E, Kostowski W, Scinska A, Danysz W (2001) Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat. Eur J Pharmacol 413 : 81 89.
    • (2001) Eur J Pharmacol , vol.413 , pp. 81-89
    • Bienkowski, P.1    Krzascik, P.2    Koros, E.3    Kostowski, W.4    Scinska, A.5    Danysz, W.6
  • 7
    • 0027359962 scopus 로고
    • Bidirectional effects of GABAergic agonists and antagonists on maintenance of voluntary ethanol intake in rats
    • Boyle AE, Segal R, Smith BR, Amit Z (1993) Bidirectional effects of GABAergic agonists and antagonists on maintenance of voluntary ethanol intake in rats. Pharmacol Biochem Behav 46 : 179 182.
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 179-182
    • Boyle, A.E.1    Segal, R.2    Smith, B.R.3    Amit, Z.4
  • 8
    • 0033978673 scopus 로고    scopus 로고
    • Prevention of cocaine-induced convulsions and lethality in mice: Effectiveness of targeting different sites on the NMDA receptor complex
    • Brackett RL, Pouw B, Blyden JF, Nour M, Matsumoto RR (2000) Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex. Neuropharmacology 39 : 407 418.
    • (2000) Neuropharmacology , vol.39 , pp. 407-418
    • Brackett, R.L.1    Pouw, B.2    Blyden, J.F.3    Nour, M.4    Matsumoto, R.R.5
  • 9
    • 0019417010 scopus 로고
    • Alcohol withdrawal reactions after chronic intake of chlordiazepoxide and ethanol
    • Chan AW, Leong FW, Schanley DL, Howe SM (1981) Alcohol withdrawal reactions after chronic intake of chlordiazepoxide and ethanol. Pharmacol Biochem Behav 15 : 185 189.
    • (1981) Pharmacol Biochem Behav , vol.15 , pp. 185-189
    • Chan, A.W.1    Leong, F.W.2    Schanley, D.L.3    Howe, S.M.4
  • 10
    • 0032982015 scopus 로고    scopus 로고
    • GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice
    • Chester JA, Cunningham CL (1999) GABA(A) receptors modulate ethanol-induced conditioned place preference and taste aversion in mice. Psychopharmacology (Berl) 144 : 363 372.
    • (1999) Psychopharmacology (Berl) , vol.144 , pp. 363-372
    • Chester, J.A.1    Cunningham, C.L.2
  • 11
    • 0021236681 scopus 로고
    • Genetic correlations with ethanol withdrawal severity
    • Crabbe JC Jr, Young ER, Kosobud A (1983) Genetic correlations with ethanol withdrawal severity. Pharmacol Biochem Behav 18 (Suppl 1 541 547.
    • (1983) Pharmacol Biochem Behav , vol.18 , Issue.SUPPL. 1 , pp. 541-547
    • Jr C. C, J.1    Young, E.R.2    Kosobud, A.3
  • 12
    • 0035139197 scopus 로고    scopus 로고
    • Role of glutamatergic and GABAergic systems in alcoholism
    • Davis KM, Wu JY (2001) Role of glutamatergic and GABAergic systems in alcoholism. J Biomed Sci 8 : 7 19.
    • (2001) J Biomed Sci , vol.8 , pp. 7-19
    • Davis, K.M.1    Wu, J.Y.2
  • 13
    • 0027213025 scopus 로고
    • Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes
    • Debono MW, Le Guern J, Canton T, Doble A, Pradier L (1993) Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 235 : 283 289.
    • (1993) Eur J Pharmacol , vol.235 , pp. 283-289
    • Debono, M.W.1    Le Guern, J.2    Canton, T.3    Doble, A.4    Pradier, L.5
  • 14
    • 0029753270 scopus 로고    scopus 로고
    • The pharmacology and mechanism of action of riluzole
    • Doble A (1996) The pharmacology and mechanism of action of riluzole. Neurology 47 (6 Suppl 4 S233 S241.
    • (1996) Neurology , vol.47 , Issue.6 SUPPL. 4
    • Doble, A.1
  • 15
    • 25844450208 scopus 로고    scopus 로고
    • Neurosteroid modulators of GABA(A) receptors differentially modulate ethanol intake patterns in male C57BL/6J mice
    • Ford MM, Nickel JD, Phillips TJ, Finn DA (2005) Neurosteroid modulators of GABA(A) receptors differentially modulate ethanol intake patterns in male C57BL/6J mice. Alcohol Clin Exp Res 29 : 1630 1640.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 1630-1640
    • Ford, M.M.1    Nickel, J.D.2    Phillips, T.J.3    Finn, D.A.4
  • 16
    • 0015416328 scopus 로고
    • An animal model for testing effects of drugs on alcohol withdrawal reactions
    • Goldstein DB (1972a) An animal model for testing effects of drugs on alcohol withdrawal reactions. J Pharmacol Exp Ther 183 : 14 22.
    • (1972) J Pharmacol Exp Ther , vol.183 , pp. 14-22
    • Goldstein, D.B.1
  • 17
    • 0015292140 scopus 로고
    • Relationship of alcohol dose to intensity of withdrawal signs in mice
    • Goldstein DB (1972b) Relationship of alcohol dose to intensity of withdrawal signs in mice. J Pharmacol Exp Ther 180 : 203 215.
    • (1972) J Pharmacol Exp Ther , vol.180 , pp. 203-215
    • Goldstein, D.B.1
  • 18
    • 0017142315 scopus 로고
    • Drinking patterns as predictors of alcohol withdrawal reactions in DBA/2J mice
    • Goldstein DB, Arnold VW (1976) Drinking patterns as predictors of alcohol withdrawal reactions in DBA/2J mice. J Pharmacol Exp Ther 199 : 408 414.
    • (1976) J Pharmacol Exp Ther , vol.199 , pp. 408-414
    • Goldstein, D.B.1    Arnold, V.W.2
  • 19
    • 0001817507 scopus 로고
    • Ethanol-like discriminative stimulus effects of non-competitive n-methyl-d-aspartate antagonists
    • Grant KA, Knisely JS, Tabakoff B, Barrett JE, Balster RL (1991) Ethanol-like discriminative stimulus effects of non-competitive n-methyl-d-aspartate antagonists. Behav Pharmacol 2 : 87 95.
    • (1991) Behav Pharmacol , vol.2 , pp. 87-95
    • Grant, K.A.1    Knisely, J.S.2    Tabakoff, B.3    Barrett, J.E.4    Balster, R.L.5
  • 20
    • 0029187835 scopus 로고
    • Cellular and behavioral neurobiology of alcohol: Receptor-mediated neuronal processes
    • Grant KA, Lovinger DM (1995) Cellular and behavioral neurobiology of alcohol: receptor-mediated neuronal processes. Clin Neurosci 3 : 155 164.
    • (1995) Clin Neurosci , vol.3 , pp. 155-164
    • Grant, K.A.1    Lovinger, D.M.2
  • 25
    • 0029609840 scopus 로고
    • GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats
    • Hodge CW, Chappelle AM, Samson HH (1995) GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats. Alcohol Clin Exp Res 19 : 1486 1493.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 1486-1493
    • Hodge, C.W.1    Chappelle, A.M.2    Samson, H.H.3
  • 26
    • 0031693278 scopus 로고    scopus 로고
    • The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions
    • Hodge CW, Cox AA (1998) The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions. Psychopharmacology (Berl) 139 : 95 107.
    • (1998) Psychopharmacology (Berl) , vol.139 , pp. 95-107
    • Hodge, C.W.1    Cox, A.A.2
  • 27
    • 0029926457 scopus 로고    scopus 로고
    • Effects of ventral tegmental microinjections of the GABAA agonist muscimol on self-administration of ethanol and sucrose
    • Hodge CW, Haraguchi M, Chappelle AM, Samson HH (1996) Effects of ventral tegmental microinjections of the GABAA agonist muscimol on self-administration of ethanol and sucrose. Pharmacol Biochem Behav 53 : 971 977.
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 971-977
    • Hodge, C.W.1    Haraguchi, M.2    Chappelle, A.M.3    Samson, H.H.4
  • 30
    • 0032031746 scopus 로고    scopus 로고
    • Discriminative stimulus effects of glutamate release inhibitors in rats trained to discriminate ethanol
    • Hundt W, Holter SM, Spanagel R (1998) Discriminative stimulus effects of glutamate release inhibitors in rats trained to discriminate ethanol. Pharmacol Biochem Behav 59 : 691 695.
    • (1998) Pharmacol Biochem Behav , vol.59 , pp. 691-695
    • Hundt, W.1    Holter, S.M.2    Spanagel, R.3
  • 32
    • 34249096118 scopus 로고    scopus 로고
    • Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice
    • Irifune M, Kikuchi N, Saida T, Takarada T, Shimizu Y, Endo C, Morita K, Dohi T, Sato T, Kawahara M (2007) Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice. Anesth Analg 104 : 1415 1421.
    • (2007) Anesth Analg , vol.104 , pp. 1415-1421
    • Irifune, M.1    Kikuchi, N.2    Saida, T.3    Takarada, T.4    Shimizu, Y.5    Endo, C.6    Morita, K.7    Dohi, T.8    Sato, T.9    Kawahara, M.10
  • 33
    • 0033842792 scopus 로고    scopus 로고
    • Effect of riluzole and gabapentin on cocaine- and methamphetamine-induced behavioral sensitization in mice
    • Itzhak Y, Martin JL (2000) Effect of riluzole and gabapentin on cocaine- and methamphetamine-induced behavioral sensitization in mice. Psychopharmacology 151 : 226 233.
    • (2000) Psychopharmacology , vol.151 , pp. 226-233
    • Itzhak, Y.1    Martin, J.L.2
  • 35
    • 0031824699 scopus 로고    scopus 로고
    • Diurnal variation in plasma ethanol levels of to and CBA mice on chronic ethanol drinking or ethanol liquid diet schedules
    • Jelic P, Shih MF, Taberner PV (1998) Diurnal variation in plasma ethanol levels of TO and CBA mice on chronic ethanol drinking or ethanol liquid diet schedules. Psychopharmacology (Berl) 138 : 143 150.
    • (1998) Psychopharmacology (Berl) , vol.138 , pp. 143-150
    • Jelic, P.1    Shih, M.F.2    Taberner, P.V.3
  • 36
    • 0026532970 scopus 로고
    • Ethanol self-administration in deprived rats: Effects of Ro15-4513 alone, and in combination with flumazenil (Ro15-1788)
    • June HL, Colker RE, Domangue KR, Perry LE, Hicks LH, June PL, Lewis MJ (1992) Ethanol self-administration in deprived rats: effects of Ro15-4513 alone, and in combination with flumazenil (Ro15-1788). Alcohol Clin Exp Res 16 : 11 16.
    • (1992) Alcohol Clin Exp Res , vol.16 , pp. 11-16
    • June, H.L.1    Colker, R.E.2    Domangue, K.R.3    Perry, L.E.4    Hicks, L.H.5    June, P.L.6    Lewis, M.J.7
  • 37
    • 0025758790 scopus 로고
    • NMDA antagonist inhibits rapid tolerance to ethanol
    • Khanna JM, Wu PH, Weiner J, Kalant H (1991) NMDA antagonist inhibits rapid tolerance to ethanol. Brain Res Bull 26 : 643 645.
    • (1991) Brain Res Bull , vol.26 , pp. 643-645
    • Khanna, J.M.1    Wu, P.H.2    Weiner, J.3    Kalant, H.4
  • 39
    • 0029806427 scopus 로고    scopus 로고
    • Oral administration of glycine and polyamine receptor antagonists blocks ethanol withdrawal seizures
    • Kotlinska J, Liljequist S (1996) Oral administration of glycine and polyamine receptor antagonists blocks ethanol withdrawal seizures. Psychopharmacology (Berl) 127 : 238 244.
    • (1996) Psychopharmacology (Berl) , vol.127 , pp. 238-244
    • Kotlinska, J.1    Liljequist, S.2
  • 42
    • 0002456867 scopus 로고    scopus 로고
    • Neurochemical mechanisms underlying alcohol withdrawal
    • Littleton J (1998) Neurochemical mechanisms underlying alcohol withdrawal. Alcohol Health Res World 22 : 13 24.
    • (1998) Alcohol Health Res World , vol.22 , pp. 13-24
    • Littleton, J.1
  • 45
    • 0026580780 scopus 로고
    • Anesthetic properties of riluzole (54274 RP), a new inhibitor of glutamate neurotransmission
    • Mantz J, Cheramy A, Thierry AM, Glowinski J, Desmonts JM (1992) Anesthetic properties of riluzole (54274 RP), a new inhibitor of glutamate neurotransmission. Anesthesiology 76 : 844 848.
    • (1992) Anesthesiology , vol.76 , pp. 844-848
    • Mantz, J.1    Cheramy, A.2    Thierry, A.M.3    Glowinski, J.4    Desmonts, J.M.5
  • 47
    • 0027762836 scopus 로고
    • The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1
    • Martin D, Thompson MA, Nadler JV (1993) The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur J Pharmacol 250 : 473 476.
    • (1993) Eur J Pharmacol , vol.250 , pp. 473-476
    • Martin, D.1    Thompson, M.A.2    Nadler, J.V.3
  • 48
    • 0026668163 scopus 로고
    • Role of the gamma-aminobutyric acid receptor/chloride channel complex in tolerance to ethanol and cross-tolerance to diazepam and pentobarbital
    • Mihic SJ, Kalant H, Liu JF, Wu PH (1992) Role of the gamma-aminobutyric acid receptor/chloride channel complex in tolerance to ethanol and cross-tolerance to diazepam and pentobarbital. J Pharmacol Exp Ther 261 : 108 113.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 108-113
    • Mihic, S.J.1    Kalant, H.2    Liu, J.F.3    Wu, P.H.4
  • 49
    • 0022362589 scopus 로고
    • 2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission - I. Anticonvulsant properties
    • Mizoule J, Meldrum B, Mazadier M, Croucher M, Ollat C, Uzan A, Legrand JJ, Gueremy C, Le Fur G (1985) 2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission - I. Anticonvulsant properties. Neuropharmacology 24 : 767 773.
    • (1985) Neuropharmacology , vol.24 , pp. 767-773
    • Mizoule, J.1    Meldrum, B.2    Mazadier, M.3    Croucher, M.4    Ollat, C.5    Uzan, A.6    Legrand, J.J.7    Gueremy, C.8    Le Fur, G.9
  • 51
    • 0028678243 scopus 로고
    • GABAA and NMDA receptor subunit mRNA expression in ethanol dependent rats
    • Morrow AL, Devaud LL, Bucci D, Smith FD (1994) GABAA and NMDA receptor subunit mRNA expression in ethanol dependent rats. Alcohol Alcohol Suppl 2 : 89 95.
    • (1994) Alcohol Alcohol Suppl , vol.2 , pp. 89-95
    • Morrow, A.L.1    Devaud, L.L.2    Bucci, D.3    Smith, F.D.4
  • 52
    • 34848923432 scopus 로고    scopus 로고
    • Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety
    • Munro G, Erichsen HK, Mirza NR (2007) Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety. Neuropharmacology 53 : 609 618.
    • (2007) Neuropharmacology , vol.53 , pp. 609-618
    • Munro, G.1    Erichsen, H.K.2    Mirza, N.R.3
  • 53
    • 0029057338 scopus 로고
    • Neurotransmitter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism
    • Nevo I, Hamon M (1995) Neurotransmitter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism. Neurochem Int 26 : 305 336.
    • (1995) Neurochem Int , vol.26 , pp. 305-336
    • Nevo, I.1    Hamon, M.2
  • 54
    • 0038163468 scopus 로고    scopus 로고
    • Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats
    • Nie H, Janak PH (2003) Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats. Psychopharmacology (Berl) 168 : 222 228.
    • (2003) Psychopharmacology (Berl) , vol.168 , pp. 222-228
    • Nie, H.1    Janak, P.H.2
  • 55
    • 0033830726 scopus 로고    scopus 로고
    • A novel neuroprotective mechanism of riluzole: Direct inhibition of protein kinase C
    • Noh KM, Hwang JY, Shin HC, Koh JY (2000) A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase C. Neurobiol Dis 7 : 375 383.
    • (2000) Neurobiol Dis , vol.7 , pp. 375-383
    • Noh, K.M.1    Hwang, J.Y.2    Shin, H.C.3    Koh, J.Y.4
  • 56
    • 0024526467 scopus 로고
    • Benzodiazepines in the treatment of alcoholism
    • Nutt D, Adinoff B, Linnoila M (1989) Benzodiazepines in the treatment of alcoholism. Recent Dev Alcohol 7 : 283 313.
    • (1989) Recent Dev Alcohol , vol.7 , pp. 283-313
    • Nutt, D.1    Adinoff, B.2    Linnoila, M.3
  • 57
    • 0033777799 scopus 로고    scopus 로고
    • Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice
    • Olive MF, Mehmert KK, Messing RO, Hodge CW (2000) Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. Eur J Neurosci 12 : 4131 4140.
    • (2000) Eur J Neurosci , vol.12 , pp. 4131-4140
    • Olive, M.F.1    Mehmert, K.K.2    Messing, R.O.3    Hodge, C.W.4
  • 58
    • 0035961170 scopus 로고    scopus 로고
    • Reduced ethanol withdrawal severity and altered withdrawal-induced c-fos expression in various brain regions of mice lacking protein kinase C-epsilon
    • Olive MF, Mehmert KK, Nannini MA, Camarini R, Messing RO, Hodge CW (2001) Reduced ethanol withdrawal severity and altered withdrawal-induced c-fos expression in various brain regions of mice lacking protein kinase C-epsilon. Neuroscience 103 : 171 179.
    • (2001) Neuroscience , vol.103 , pp. 171-179
    • Olive, M.F.1    Mehmert, K.K.2    Nannini, M.A.3    Camarini, R.4    Messing, R.O.5    Hodge, C.W.6
  • 59
    • 0031713499 scopus 로고    scopus 로고
    • Ethanol-reinforced behaviour in the rat: Effects of uncompetitive NMDA receptor antagonist, memantine
    • Piasecki J, Koros E, Dyr W, Kostowski W, Danysz W, Bienkowski P (1998) Ethanol-reinforced behaviour in the rat: effects of uncompetitive NMDA receptor antagonist, memantine. Eur J Pharmacol 354 : 135 143.
    • (1998) Eur J Pharmacol , vol.354 , pp. 135-143
    • Piasecki, J.1    Koros, E.2    Dyr, W.3    Kostowski, W.4    Danysz, W.5    Bienkowski, P.6
  • 61
    • 0026485324 scopus 로고
    • Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens
    • Rassnick S, Pulvirenti L, Koob GF (1992) Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens. Psychopharmacology (Berl) 109 : 92 98.
    • (1992) Psychopharmacology (Berl) , vol.109 , pp. 92-98
    • Rassnick, S.1    Pulvirenti, L.2    Koob, G.F.3
  • 62
    • 0025808709 scopus 로고
    • Management of the alcohol withdrawal syndrome
    • Romach MK, Sellers EM (1991) Management of the alcohol withdrawal syndrome. Annu Rev Med 42 : 323 340.
    • (1991) Annu Rev Med , vol.42 , pp. 323-340
    • Romach, M.K.1    Sellers, E.M.2
  • 63
    • 0025890432 scopus 로고
    • Anticonvulsant and sleep-waking influences of riluzole in a rat model of absence epilepsy
    • Romettino S, Lazdunski M, Gottesmann C (1991) Anticonvulsant and sleep-waking influences of riluzole in a rat model of absence epilepsy. Eur J Pharmacol 199 : 371 373.
    • (1991) Eur J Pharmacol , vol.199 , pp. 371-373
    • Romettino, S.1    Lazdunski, M.2    Gottesmann, C.3
  • 64
    • 0022497706 scopus 로고
    • Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats
    • Samson HH (1986) Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats. Alcohol Clin Exp Res 10 : 436 442.
    • (1986) Alcohol Clin Exp Res , vol.10 , pp. 436-442
    • Samson, H.H.1
  • 65
    • 0001353578 scopus 로고
    • Initiation of Ethanol-maintained Behavior: A Comparison of Animal Models and Their Implication to Human Drinking
    • in Advanced Behavioral Pharmacology Thompson, T. Dews, P.B. Barrett, J.E. eds. pp. Lawrence Erlbaum. Hillsdale, NJ.
    • Samson HH (1987) in Initiation of ethanol-maintained behavior: a comparison of animal models and their implication to human drinking. in Advanced Behavioral Pharmacology, Vol. 6, Neurobehavioral Pharmacology (Thompson T, Dews PB, Barrett JE eds pp 221 248. Lawrence Erlbaum, Hillsdale, NJ.
    • (1987) Neurobehavioral Pharmacology , vol.6 , pp. 221-248
    • Samson, H.H.1
  • 66
    • 0033678985 scopus 로고    scopus 로고
    • Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation
    • Schwenkreis P, Liepert J, Witscher K, Fischer W, Weiller C, Malin JP, Tegenthoff M (2000) Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation. Exp Brain Res 135 : 293 299.
    • (2000) Exp Brain Res , vol.135 , pp. 293-299
    • Schwenkreis, P.1    Liepert, J.2    Witscher, K.3    Fischer, W.4    Weiller, C.5    Malin, J.P.6    Tegenthoff, M.7
  • 67
    • 0345493901 scopus 로고    scopus 로고
    • Riluzole decreases the abstinence syndrome and physical dependence in morphine-dependent mice
    • Sepulveda J, Astorga JG, Contreras E (1999) Riluzole decreases the abstinence syndrome and physical dependence in morphine-dependent mice. Eur J Pharmacol 379 : 59 62.
    • (1999) Eur J Pharmacol , vol.379 , pp. 59-62
    • Sepulveda, J.1    Astorga, J.G.2    Contreras, E.3
  • 68
    • 0024815156 scopus 로고
    • Modulation of ion channel activity: A key function of the protein kinase C enzyme family
    • Shearman MS, Sekiguchi K, Nishizuka Y (1989) Modulation of ion channel activity: a key function of the protein kinase C enzyme family. Pharmacol Rev 41 : 211 237.
    • (1989) Pharmacol Rev , vol.41 , pp. 211-237
    • Shearman, M.S.1    Sekiguchi, K.2    Nishizuka, Y.3
  • 69
    • 0026733351 scopus 로고
    • GABAergic involvement in the acquisition of voluntary ethanol intake in laboratory rats
    • Smith BR, Robidoux J, Amit Z (1992) GABAergic involvement in the acquisition of voluntary ethanol intake in laboratory rats. Alcohol Alcohol 27 : 227 231.
    • (1992) Alcohol Alcohol , vol.27 , pp. 227-231
    • Smith, B.R.1    Robidoux, J.2    Amit, Z.3
  • 71
    • 0028216874 scopus 로고
    • The protein kinase C family for neuronal signaling
    • Tanaka C, Nishizuka Y (1994) The protein kinase C family for neuronal signaling. Annu Rev Neurosci 17 : 551 567.
    • (1994) Annu Rev Neurosci , vol.17 , pp. 551-567
    • Tanaka, C.1    Nishizuka, Y.2
  • 72
    • 0032512783 scopus 로고    scopus 로고
    • Blockade of morphine- and amphetamine-induced conditioned place preference in the rat by riluzole
    • Tzschentke TM, Schmidt WJ (1998) Blockade of morphine- and amphetamine-induced conditioned place preference in the rat by riluzole. Neurosci Lett 242 : 114 116.
    • (1998) Neurosci Lett , vol.242 , pp. 114-116
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 73
    • 0030981003 scopus 로고    scopus 로고
    • Riluzole: A new agent for amyotrophic lateral sclerosis
    • Wagner ML, Landis BE (1997) Riluzole: a new agent for amyotrophic lateral sclerosis. Ann Pharmacother 31 : 738 744.
    • (1997) Ann Pharmacother , vol.31 , pp. 738-744
    • Wagner, M.L.1    Landis, B.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.