메뉴 건너뛰기




Volumn 105, Issue 29, 2008, Pages 9880-9885

The implications of human metabolic network topology for disease comorbidity

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL METABOLISM; COMORBIDITY; GENE EXPRESSION; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL;

EID: 48249158278     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802208105     Document Type: Article
Times cited : (413)

References (41)
  • 2
    • 33644877806 scopus 로고    scopus 로고
    • Argmann CA, Chambon P, Auwerx J (2005) Mouse phenogenomics: The fast track to systems metabolism. Cell Metab 2:349-360.
    • Argmann CA, Chambon P, Auwerx J (2005) Mouse phenogenomics: The fast track to "systems metabolism." Cell Metab 2:349-360.
  • 3
    • 34447521460 scopus 로고    scopus 로고
    • Human disease classification in the post-genomic era: A complex systems approach to human pathobiology
    • Loscalzo J, Kohane I, Barabási A-L (2007) Human disease classification in the post-genomic era: A complex systems approach to human pathobiology. Mol Syst Biol 3:124.
    • (2007) Mol Syst Biol , vol.3 , pp. 124
    • Loscalzo, J.1    Kohane, I.2    Barabási, A.-L.3
  • 4
    • 33749335282 scopus 로고    scopus 로고
    • The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J, et al. (2006) The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease. Science 313:1929-1935.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1
  • 5
    • 33947095027 scopus 로고    scopus 로고
    • A human phenome-interactome network of protein complexes implicated in genetic disorders
    • Lage K, et al. (2007) A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 25:309-316.
    • (2007) Nat Biotechnol , vol.25 , pp. 309-316
    • Lage, K.1
  • 6
    • 36349010138 scopus 로고    scopus 로고
    • Protein interactions and disease: Computational approaches to uncover the etiology of diseases
    • Kann, MG (2007) Protein interactions and disease: Computational approaches to uncover the etiology of diseases. Brief Bioinform. 8:333-346.
    • (2007) Brief Bioinform , vol.8 , pp. 333-346
    • Kann, M.G.1
  • 7
    • 22844446947 scopus 로고    scopus 로고
    • An integrative genomics approach to infer causal associations between gene expression and disease
    • Schadt EE, et al (2005) An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet 37:710-717.
    • (2005) Nat Genet , vol.37 , pp. 710-717
    • Schadt, E.E.1
  • 9
    • 33846326304 scopus 로고    scopus 로고
    • Genetic screening for signal transduction in the era of network biology
    • Friedman A, Perrimon N (2007) Genetic screening for signal transduction in the era of network biology. Cell 128:225-231.
    • (2007) Cell , vol.128 , pp. 225-231
    • Friedman, A.1    Perrimon, N.2
  • 10
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: Understanding the cell's functional organization
    • Barabási A-L, Oltvai ZN (2004) Network biology: Understanding the cell's functional organization. Nat Rev Genet 5:101-113.
    • (2004) Nat Rev Genet , vol.5 , pp. 101-113
    • Barabási, A.-L.1    Oltvai, Z.N.2
  • 11
    • 27944493925 scopus 로고    scopus 로고
    • Scale-free networks in cell biology
    • Albert R (2005) Scale-free networks in cell biology. J Cell Sci 118:4947-4957.
    • (2005) J Cell Sci , vol.118 , pp. 4947-4957
    • Albert, R.1
  • 12
    • 34249736324 scopus 로고    scopus 로고
    • Biological impacts and context of network theory
    • Almaas E (2007) Biological impacts and context of network theory. J Exp Biol 210:1548-1558.
    • (2007) J Exp Biol , vol.210 , pp. 1548-1558
    • Almaas, E.1
  • 14
    • 34247623628 scopus 로고    scopus 로고
    • Getting connected: Analysis and principles of biological networks
    • Zhu X, Gerstein M, Snyder M (2007) Getting connected: Analysis and principles of biological networks. Genes Dev 21:1010-1024.
    • (2007) Genes Dev , vol.21 , pp. 1010-1024
    • Zhu, X.1    Gerstein, M.2    Snyder, M.3
  • 15
    • 33644874819 scopus 로고    scopus 로고
    • From genomics to chemical genomics
    • Kanehisa M, et al. (2006) From genomics to chemical genomics. Nucleic Acids Res 34:D354-D357.
    • (2006) Nucleic Acids Res , vol.34
    • Kanehisa, M.1
  • 16
    • 33846910173 scopus 로고    scopus 로고
    • Global reconstruction of the human metabolic network based on genomic and bibliomic data
    • Duarte ND, et al. (2007) Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc Natl Acad Sci USA 104:1777-1782.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 1777-1782
    • Duarte, N.D.1
  • 17
    • 9544253891 scopus 로고    scopus 로고
    • Genome-scale models of microbial cells: Evaluating the consequences of constraints
    • Price ND, Reed JL, Palsson BO (2004) Genome-scale models of microbial cells: Evaluating the consequences of constraints. Nat Rev Microbiol 2:886-897.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 886-897
    • Price, N.D.1    Reed, J.L.2    Palsson, B.O.3
  • 18
    • 34547140875 scopus 로고    scopus 로고
    • The human disease network
    • Goh K-I, et al. (2007) The human disease network. Proc Natl Acad Sci USA 104:8685-8690.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 8685-8690
    • Goh, K.-I.1
  • 19
    • 34547322851 scopus 로고    scopus 로고
    • Optimal flux patterns in cellular metabolic networks
    • Almaas, E (2007) Optimal flux patterns in cellular metabolic networks. Chaos 17:026107.
    • (2007) Chaos , vol.17 , pp. 026107
    • Almaas, E.1
  • 21
    • 0035823264 scopus 로고    scopus 로고
    • The small world inside large metabolic networks
    • Wagner A, Fell D (2001) The small world inside large metabolic networks. R Soc London Ser B 268:1803-1810.
    • (2001) R Soc London Ser B , vol.268 , pp. 1803-1810
    • Wagner, A.1    Fell, D.2
  • 23
    • 13444266370 scopus 로고    scopus 로고
    • Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
    • Hamosh A, Scott AF, Amberger JS, Bocchini CA, McKusick VA (2005) Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res 33:D514-D517.
    • (2005) Nucleic Acids Res , vol.33
    • Hamosh, A.1    Scott, A.F.2    Amberger, J.S.3    Bocchini, C.A.4    McKusick, V.A.5
  • 27
    • 0038483826 scopus 로고    scopus 로고
    • Emergence of scaling in random networks
    • Barabási A-L, Albert R (1999) Emergence of scaling in random networks. Science 286:509-512.
    • (1999) Science , vol.286 , pp. 509-512
    • Barabási, A.-L.1    Albert, R.2
  • 28
    • 21444445235 scopus 로고    scopus 로고
    • Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues
    • Ge X, et al. (2005) Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 86:127-141.
    • (2005) Genomics , vol.86 , pp. 127-141
    • Ge, X.1
  • 29
    • 33646200155 scopus 로고    scopus 로고
    • Expression dynamics of a cellular metabolic network
    • Kharchenko P, Church GM, Vitkup, D (2005) Expression dynamics of a cellular metabolic network. Mol Syst Biol 1:2005.0016.
    • (2005) Mol Syst Biol , vol.1 , pp. 0016
    • Kharchenko, P.1    Church, G.M.2    Vitkup, D.3
  • 30
    • 8544223537 scopus 로고    scopus 로고
    • Hierarchical thinking in network biology: The unbiased modularization of biochemical networks
    • Papin JA, Reed JL, Palsson BO (2004) Hierarchical thinking in network biology: The unbiased modularization of biochemical networks. Trends Biochem Sci 29:641-647.
    • (2004) Trends Biochem Sci , vol.29 , pp. 641-647
    • Papin, J.A.1    Reed, J.L.2    Palsson, B.O.3
  • 31
    • 1242274402 scopus 로고    scopus 로고
    • Flux coupling analysis of genome-scale metabolic network reconstructions
    • Burgard AP, Nikolaev EV, Schilling CH, Maranas CD (2004) Flux coupling analysis of genome-scale metabolic network reconstructions. Genome Res 14:301-312.
    • (2004) Genome Res , vol.14 , pp. 301-312
    • Burgard, A.P.1    Nikolaev, E.V.2    Schilling, C.H.3    Maranas, C.D.4
  • 32
    • 11244341009 scopus 로고    scopus 로고
    • Elucidation and structural analysis of conserved pools for genome-scale metabolic reconstructions
    • Nikolaev EV, Burgard AP, Maranas CD (2005) Elucidation and structural analysis of conserved pools for genome-scale metabolic reconstructions. Biophys J 88:37-49.
    • (2005) Biophys J , vol.88 , pp. 37-49
    • Nikolaev, E.V.1    Burgard, A.P.2    Maranas, C.D.3
  • 34
    • 0028470520 scopus 로고
    • Using Medicare claims for outcomes research
    • Mitchell JB, et al. (1994) Using Medicare claims for outcomes research. Med Care 32:JS38-JS51.
    • (1994) Med Care , vol.32
    • Mitchell, J.B.1
  • 35
    • 34547146985 scopus 로고    scopus 로고
    • Barabási A-L (2007) Network medicine - From obesity to the diseasome. New Eng J Med 357:404-407.
    • Barabási A-L (2007) Network medicine - From obesity to the "diseasome." New Eng J Med 357:404-407.
  • 37
    • 55449114287 scopus 로고    scopus 로고
    • The activity reaction core and plasticity of metabolic networks
    • Almaas E, Oltvai ZN, Barabási A-L (2005) The activity reaction core and plasticity of metabolic networks. PLoS Comput Biol 1:0557-0563.
    • (2005) PLoS Comput Biol , vol.1 , pp. 0557-0563
    • Almaas, E.1    Oltvai, Z.N.2    Barabási, A.-L.3
  • 38
    • 33845886093 scopus 로고    scopus 로고
    • Nature insight: Obesity and diabetes
    • Nath D, Heemels M-T, Anson L (2006) Nature insight: Obesity and diabetes. Nature 444:839-888.
    • (2006) Nature , vol.444 , pp. 839-888
    • Nath, D.1    Heemels, M.-T.2    Anson, L.3
  • 39
    • 0034715982 scopus 로고    scopus 로고
    • Hereditary catalase deficiencies and increased risk of diabetes
    • Goth L, Eaton JW (2000) Hereditary catalase deficiencies and increased risk of diabetes. Lancet 356:1820-1821.
    • (2000) Lancet , vol.356 , pp. 1820-1821
    • Goth, L.1    Eaton, J.W.2
  • 40
    • 28844488320 scopus 로고    scopus 로고
    • The energy-less red blood cell is lost: Erythrocyte enzyme abnormalities of glycolysis
    • Wijk V, Solinge V (2005) The energy-less red blood cell is lost: Erythrocyte enzyme abnormalities of glycolysis. Blood 106:4034-4042.
    • (2005) Blood , vol.106 , pp. 4034-4042
    • Wijk, V.1    Solinge, V.2
  • 41
    • 34547887655 scopus 로고    scopus 로고
    • Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity
    • Beg QK, et al. (2007) Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity. Proc Natl Acad Sci USA 104:12663-12668.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12663-12668
    • Beg, Q.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.