Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: Effect of nutrient supplementation

Biotechnology and Bioengineering

Volumn 108, Issue 9, 2011, Pages 2182-2192

  Han, Young Kue ^a   Ha, Tae Kwang ^a   Lee, So Jeong ^a   Lee, Jae Seong ^a   Lee, Gyun Min ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Apoptosis; Autophagy; Fed batch culture; RCHO cells

Indexed keywords

ANTIBODY PRODUCTION; AUTOPHAGY; BAFILOMYCIN; BATCH CULTURE; BIOREACTOR CULTURES; CELL LINES; CELL SURVIVAL; CHINESE HAMSTER OVARY; CHINESE HAMSTER OVARY CELLS; FED BATCHES; FED-BATCH CULTURES; FLASK CULTURE; NUTRIENT DEPLETION; PROGRAMMED CELL DEATHS; PROTEIN PRODUCTION; RAPAMYCIN; RCHO CELLS; TYPE II;

AMINO ACIDS; ANTIBODIES; BIOREACTORS; CELL DEATH; GLUCOSE; NUTRIENTS;

BATCH CELL CULTURE;

AMINO ACID; BAFILOMYCIN A1; CASPASE 7; DNA; GLUCOSE; RAPAMYCIN;

ANIMAL CELL; ANTIBODY PRODUCTION; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOREACTOR; CELL CULTURE; CHO CELL; CONTROLLED STUDY; DNA FRAGMENTATION; FED BATCH CULTURE; FEMALE; NONHUMAN; NUTRIENT MANAGEMENT;

ANIMALS; ANTIBODIES; APOPTOSIS; AUTOPHAGY; BIOREACTORS; CASPASE 7; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; CULTURE MEDIA; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS;

EID: 79960453559     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23165     Document Type: Article

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