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Volumn 103, Issue 4, 2009, Pages 757-766

Effect of Bcl-xL overexpression on apoptosis and autophagy in recombinant Chinese hamster ovary cells under nutrient-deprived condition

Author keywords

Apoptosis; Autophagy; Bcl xL; Inducible expression; rCHO cells

Indexed keywords

APOPTOSIS; AUTOPHAGY; BCL-XL; INDUCIBLE EXPRESSION; RCHO CELLS;

EID: 67650218292     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22298     Document Type: Article
Times cited : (50)

References (55)
  • 1
    • 0035146929 scopus 로고    scopus 로고
    • Life-or-death decisions by the Bcl-2 protein family
    • DOI 10.1016/S0968-0004(00)01740-0, PII S0968000400017400
    • Adams JM, Cory S. 2001. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem Sci 26(1):61-66. (Pubitemid 32124712)
    • (2001) Trends in Biochemical Sciences , vol.26 , Issue.1 , pp. 61-66
    • Adams, J.M.1    Cory, S.2
  • 4
    • 1642325279 scopus 로고    scopus 로고
    • Life and death in mammalian cell culture: Strategies for apoptosis inhibition
    • DOI 10.1016/j.tibtech.2004.02.004, PII S0167779904000502
    • Arden N, Betenbaugh MJ. 2004. Life and death in mammalian cell culture: Strategies for apoptosis inhibition. Trends Biotechnol 22(4):174-180. (Pubitemid 38368176)
    • (2004) Trends in Biotechnology , vol.22 , Issue.4 , pp. 174-180
    • Arden, N.1    Betenbaugh, M.J.2
  • 5
    • 0034948738 scopus 로고    scopus 로고
    • The autophagosomal-lysosomal compartment in programmed cell death
    • DOI 10.1038/sj.cdd.4400852
    • Bursch W. 2001. The autophagosomal-lysosomal compartment in programmed cell death. Cell Death Differ 8(6):569-581. (Pubitemid 32590778)
    • (2001) Cell Death and Differentiation , vol.8 , Issue.6 , pp. 569-581
    • Bursch, W.1
  • 6
    • 25144476279 scopus 로고    scopus 로고
    • L mediates increased production of humanized monoclonal antibodies in chinese hamster ovary cells
    • DOI 10.1002/bit.20551
    • Chiang GG, Sisk WP. 2005. Bcl-x(L) mediates increased production of humanized monoclonal antibodies in Chinese hamster ovary cells. Biotechnol Bioeng 91(7):779-792. (Pubitemid 41344680)
    • (2005) Biotechnology and Bioengineering , vol.91 , Issue.7 , pp. 779-792
    • Chiang, G.G.1    Sisk, W.P.2
  • 7
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • DOI 10.1038/sj.onc.1207102
    • Cory S, Huang DC, Adams JM. 2003. The Bcl-2 family: Roles in cell survival and oncogenesis. Oncogene 22(53):8590-8607. (Pubitemid 38028528)
    • (2003) Oncogene , vol.22 , Issue.53 REV. ISS. 7 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.S.2    Adams, J.M.3
  • 9
    • 34547689505 scopus 로고    scopus 로고
    • Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1
    • DOI 10.1016/j.jmb.2007.06.069, PII S0022283607008765
    • Feng W, Huang S, Wu H, Zhang M. 2007. Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. J Mol Biol 372(1):223-235. (Pubitemid 47223231)
    • (2007) Journal of Molecular Biology , vol.372 , Issue.1 , pp. 223-235
    • Feng, W.1    Huang, S.2    Wu, H.3    Zhang, M.4
  • 10
    • 34249798692 scopus 로고    scopus 로고
    • Autophagic and apoptotic response to stress signals in mammalian cells
    • DOI 10.1016/j.abb.2007.02.006, PII S0003986107000793, Highlight Issue: Pro- and antiapoptotic Signalling
    • Ferraro E, Cecconi F. 2007. Autophagic and apoptotic response to stress signals in mammalian cells. Arch Biochem Biophys 462(2):210-219. (Pubitemid 46856320)
    • (2007) Archives of Biochemistry and Biophysics , vol.462 , Issue.2 , pp. 210-219
    • Ferraro, E.1    Cecconi, F.2
  • 11
    • 34447303773 scopus 로고    scopus 로고
    • Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese Hamster Ovary cells
    • DOI 10.1002/bit.21222
    • Figueroa B, Jr., Ailor E, Osborne D, Hardwick JM, Reff M, Betenbaugh MJ. 2007. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells. Biotechnol Bioeng 97(4): 877-892. (Pubitemid 47051057)
    • (2007) Biotechnology and Bioengineering , vol.97 , Issue.4 , pp. 877-892
    • Figueroa Jr., B.1    Ailor, E.2    Osborne, D.3    Hardwick, J.M.4    Reff, M.5    Betenbaugh, M.J.6
  • 12
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89(12):5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.12 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 14
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • DOI 10.1038/sj.onc.1207521
    • Gozuacik D, Kimchi A. 2004. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23(16):2891-2906. (Pubitemid 38638851)
    • (2004) Oncogene , vol.23 , Issue.16 REV. ISS. 2 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 15
    • 38049056162 scopus 로고    scopus 로고
    • Autophagy and apoptosis in Chinese hamster ovary cell culture
    • Hwang SO, Lee GM. 2008a. Autophagy and apoptosis in Chinese hamster ovary cell culture. Autophagy 4(1):70-72.
    • (2008) Autophagy , vol.4 , Issue.1 , pp. 70-72
    • Hwang, S.O.1    Lee, G.M.2
  • 16
    • 38449096145 scopus 로고    scopus 로고
    • Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture
    • DOI 10.1002/bit.21589
    • Hwang SO, Lee GM. 2008b. Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture. Biotechnol Bioeng 99(3):678-685. (Pubitemid 351158265)
    • (2008) Biotechnology and Bioengineering , vol.99 , Issue.3 , pp. 678-685
    • Sun, O.H.1    Lee, G.M.2
  • 17
    • 0037274196 scopus 로고    scopus 로고
    • Effect of doxycycline-regulated ERp57 expression on specific thrombopoietin productivity of recombinant CHO cells
    • DOI 10.1021/bp025578m
    • Hwang SO, Chung JY, Lee GM. 2003. Effect of doxycycline-regulated ERp57 expression on specific thrombopoietin productivity of recombinant CHO cells. Biotechnol Prog 19(1):179-184. (Pubitemid 36219320)
    • (2003) Biotechnology Progress , vol.19 , Issue.1 , pp. 179-184
    • Hwang, S.O.1    Chung, J.Y.2    Lee, G.M.3
  • 19
    • 0029876247 scopus 로고    scopus 로고
    • Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition
    • Kayalar C, Ord T, Testa MP, Zhong LT, Bredesen DE. 1996. Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition. Proc Natl Acad Sci USA 93(5):2234-2238.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.5 , pp. 2234-2238
    • Kayalar, C.1    Ord, T.2    Testa, M.P.3    Zhong, L.T.4    Bredesen, D.E.5
  • 20
    • 33947404375 scopus 로고    scopus 로고
    • Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1
    • Kessel D, Reiners JJ, Jr. 2007. Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1. Cancer Lett 249(2):294-299.
    • (2007) Cancer Lett , vol.249 , Issue.2 , pp. 294-299
    • Kessel, D.1    Reiners Jr., J.J.2
  • 21
    • 0001162423 scopus 로고    scopus 로고
    • Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production
    • DOI 10.1002/1097-0290(2000)71:3<184::AID-BIT1008>3.0.CO;2-W
    • Kim NS, Lee GM. 2000. Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production. Biotechnol Bioeng 71(3):184-193. (Pubitemid 32381138)
    • (2000) Biotechnology and Bioengineering , vol.71 , Issue.3 , pp. 184-193
    • Kim, N.S.1    Lee, G.M.2
  • 22
    • 0037161629 scopus 로고    scopus 로고
    • Response of recombinant Chinese hamster ovary cells to hyperosmotic pressure: Effect of Bcl-2 overexpression
    • DOI 10.1016/S0168-1656(02)00011-1, PII S0168165602000111
    • Kim NS, Lee GM. 2002. Response of recombinant Chinese hamster ovary cells to hyperosmotic pressure: Effect of Bcl-2 overexpression. J Biotechnol 95(3):237-248. (Pubitemid 34465467)
    • (2002) Journal of Biotechnology , vol.95 , Issue.3 , pp. 237-248
    • Kim, N.S.1    Lee, G.M.2
  • 23
    • 40449127353 scopus 로고    scopus 로고
    • Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine γ-herpesvirus 68
    • DOI 10.1371/journal.ppat.0040025
    • Ku B, Woo JS, Liang C, Lee KH, Hong HS, Xiaofei E, Kim KS, Jun JU, Oh BH. 2008. Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gammaherpesvirus 68. PLoS Pathog 4(2):e25. (Pubitemid 351343766)
    • (2008) PLoS Pathogens , vol.4 , Issue.2
    • Ku, B.1    Woo, J.-S.2    Liang, C.3    Lee, K.-H.4    Hong, H.-S.5    Kim, K.-S.6    Jung, J.U.7    Oh, B.-H.8
  • 24
    • 12944308330 scopus 로고    scopus 로고
    • Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
    • DOI 10.1016/j.cell.2005.01.005, PII S0092867405000437
    • Levine B. 2005. Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense. Cell 120(2):159-162. (Pubitemid 40174758)
    • (2005) Cell , vol.120 , Issue.2 , pp. 159-162
    • Levine, B.1
  • 25
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • DOI 10.1016/S1534-5807(04)00099-1, PII S1534580704000991
    • Levine B, Klionsky DJ. 2004. Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev Cell 6(4):463-477. (Pubitemid 38456176)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 26
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • Levine B, Yuan J. 2005. Autophagy in cell death: An innocent convict? J Clin Invest 115(10):2679-2688.
    • (2005) J Clin Invest , vol.115 , Issue.10 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 27
    • 48249092267 scopus 로고    scopus 로고
    • Bcl-2 family members: Dual regulators of apoptosis and autophagy
    • Levine B, Sinha S, Kroemer G. 2008. Bcl-2 family members: Dual regulators of apoptosis and autophagy. Autophagy 4(5):600-606.
    • (2008) Autophagy , vol.4 , Issue.5 , pp. 600-606
    • Levine, B.1    Sinha, S.2    Kroemer, G.3
  • 29
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B. 1999. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402(6762):672-676. (Pubitemid 129516338)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 30
    • 33745751085 scopus 로고    scopus 로고
    • Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
    • Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU. 2006. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8(7):688-699.
    • (2006) Nat Cell Biol , vol.8 , Issue.7 , pp. 688-699
    • Liang, C.1    Feng, P.2    Ku, B.3    Dotan, I.4    Canaani, D.5    Oh, B.H.6    Jung, J.U.7
  • 31
    • 33749435598 scopus 로고    scopus 로고
    • RNAi suppression of Bax and Bak enhances viability in fed-batch cultures of CHO cells
    • DOI 10.1016/j.ymben.2006.05.005, PII S1096717606000462
    • Lim SF, Chuan KH, Liu S, Loh SO, Chung BY, Ong CC, Song Z. 2006. RNAi suppression of Bax and Bak enhances viability in fed-batch cultures of CHO cells. Metab Eng 8(6):509-522. (Pubitemid 44512161)
    • (2006) Metabolic Engineering , vol.8 , Issue.6 , pp. 509-522
    • Lim, S.F.1    Chuan, K.H.2    Liu, S.3    Loh, S.O.H.4    Chung, B.Y.F.5    Ong, C.C.6    Song, Z.7
  • 32
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. 1998. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94(4):481-490. (Pubitemid 28391864)
    • (1998) Cell , vol.94 , Issue.4 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 35
    • 24744445331 scopus 로고    scopus 로고
    • Amino acid deprivation induces both apoptosis and autophagy in murine C2C12 muscle cells
    • DOI 10.1007/s10529-005-0007-y
    • Martinet W, De Meyer GR, Herman AG, Kockx MM. 2005. Amino acid deprivation induces both apoptosis and autophagy in murine C2C12 muscle cells. Biotechnol Lett 27(16):1157-1163. (Pubitemid 41297964)
    • (2005) Biotechnology Letters , vol.27 , Issue.16 , pp. 1157-1163
    • Martinet, W.1    De Meyer, G.R.Y.2    Herman, A.G.3    Kockx, M.M.4
  • 36
    • 0033589374 scopus 로고    scopus 로고
    • A novel autoregulated proliferation-controlled production process using recombinant CHO cells
    • DOI 10.1002/(SICI)1097-0290(19991020)65:2<144::AID-BIT3>3.0.CO;2-Q
    • Mazur X, Eppenberger HM, Bailey JE, Fussenegger M. 1999. A novel autoregulated proliferation-controlled production process using recombinant CHO cells. Biotechnol Bioeng 65(2):144-150. (Pubitemid 29441449)
    • (1999) Biotechnology and Bioengineering , vol.65 , Issue.2 , pp. 144-150
    • Mazur, X.1    Eppenberger, H.M.2    Bailey, J.E.3    Fussenegger, M.4
  • 37
    • 0035916380 scopus 로고    scopus 로고
    • Comparative characterization of cell death between Sf9 insect cells and hybridoma cultures
    • DOI 10.1002/1097-0290(20000220)72:4<441::AID-BIT1006>3.0.CO;2-3
    • Meneses-Acosta A, Mendonça R, Merchant H, Covarrubias L, Ramírez O. 2001. Comparative characterization of cell death between Sf9 insect cells and hybridoma cultures. Biotechnol Bioeng 72(4):441-457. (Pubitemid 32142445)
    • (2001) Biotechnology and Bioengineering , vol.72 , Issue.4 , pp. 441-457
    • Meneses-Acosta, A.1    Mendona, R.Z.2    Merchant, H.3    Covarrubias, L.4    Ramrez, O.T.5
  • 38
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N, Yoshimori T. 2007. How to interpret LC3 immunoblotting. Autophagy 3(6):542-545.
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 39
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. 2004. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15(3):1101-1111.
    • (2004) Mol Biol Cell , vol.15 , Issue.3 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 40
    • 34249037565 scopus 로고    scopus 로고
    • L-beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
    • DOI 10.1074/jbc.M700492200
    • Oberstein A, Jeffrey PD, Shi Y. 2007. Crystal structure of the Bcl-xL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem 282(17):13123-13132. (Pubitemid 47100641)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.17 , pp. 13123-13132
    • Oberstein, A.1    Jeffrey, P.D.2    Shi, Y.3
  • 42
    • 0034520466 scopus 로고    scopus 로고
    • Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells
    • DOI 10.1038/sj.cdd.4400759
    • Saeki K, Yuo A, Okuma E, Yazaki Y, Susin SA, Kroemer G, Takaku F. 2000. Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells. Cell Death Differ 7(12): 1263-1269. (Pubitemid 32042234)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.12 , pp. 1263-1269
    • Saeki, K.1    Yuo, A.2    Okuma, E.3    Yazaki, Y.4    Susin, S.A.5    Kroemer, G.6    Takaku, F.7
  • 43
    • 0037419710 scopus 로고    scopus 로고
    • Study of caspase inhibitors for limiting death in mammalian cell culture
    • DOI 10.1002/bit.10473
    • Sauerwald TM, Oyler GA, Betenbaugh MJ. 2003. Study of caspase inhibitors for limiting death in mammalian cell culture. Biotechnol Bioeng 81(3): 329-340. (Pubitemid 36098489)
    • (2003) Biotechnology and Bioengineering , vol.81 , Issue.3 , pp. 329-340
    • Sauerwald, T.M.1    Oyler, G.A.2    Betenbaugh, M.J.3
  • 45
    • 31144454896 scopus 로고    scopus 로고
    • Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria
    • DOI 10.1128/JVI.80.3.1140-1151.2006
    • Su J, Wang G, Barrett JW, Irvine TS, Gao X, McFadden G. 2006. Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondria. J Virol 80(3):1140-1151. (Pubitemid 43134071)
    • (2006) Journal of Virology , vol.80 , Issue.3 , pp. 1140-1151
    • Su, J.1    Wang, G.2    Barrett, J.W.3    Irvine, T.S.4    Gao, X.5    McFadden, G.6
  • 46
    • 35549010214 scopus 로고    scopus 로고
    • Influence of co-down-regulation of caspase-3 and caspase-7 by siRNAs on sodium butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin
    • DOI 10.1016/j.ymben.2007.08.001, PII S1096717607000468
    • Sung YH, Lee JS, Park SH, Koo J, Lee GM. 2007. Influence of co-down-regulation of caspase-3 and caspase-7 by siRNAs on sodium butyrateinduced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. Metab Eng 9(5-6):452-464. (Pubitemid 350016972)
    • (2007) Metabolic Engineering , vol.9 , Issue.5-6 , pp. 452-464
    • Sung, Y.H.1    Lee, J.S.2    Park, S.H.3    Koo, J.4    Lee, G.M.5
  • 47
    • 1842832918 scopus 로고    scopus 로고
    • Catalytic activity of caspase-3 is required for its degradation: Stabilization of the active complex by synthetic inhibitors
    • DOI 10.1038/sj.cdd.4401360
    • Tawa P, Hell K, Giroux A, Grimm E, Han Y, Nicholson DW, Xanthoudakis S. 2004. Catalytic activity of caspase-3 is required for its degradation: Stabilization of the active complex by synthetic inhibitors. Cell Death Differ 11(4):439-447. (Pubitemid 38489421)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.4 , pp. 439-447
    • Tawa, P.1    Hell, K.2    Giroux, A.3    Grimm, E.4    Han, Y.5    Nicholson, D.W.6    Xanthoudakis, S.7
  • 48
    • 0034607272 scopus 로고    scopus 로고
    • Influence of Bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody
    • DOI 10.1002/(SICI)1097-0290(20000405)68:1<31::AID-BIT4>3.0.CO;2-L
    • Tey BT, Singh RP, Piredda L, Piacentini M, Al-Rubeai M. 2000. Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody. Biotechnol Bioeng 68(1): 31-43. (Pubitemid 30163490)
    • (2000) Biotechnology and Bioengineering , vol.68 , Issue.1 , pp. 31-43
    • Tey, B.T.1    Singh, R.P.2    Piredda, L.3    Piacentini, M.4    Al-Rubeai, M.5
  • 49
    • 38049115875 scopus 로고    scopus 로고
    • Apoptosis and autophagy: Regulatory connections between two supposedly different processes
    • Thorburn A. 2008. Apoptosis and autophagy: Regulatory connections between two supposedly different processes. Apoptosis 13(1):1-9.
    • (2008) Apoptosis , vol.13 , Issue.1 , pp. 1-9
    • Thorburn, A.1
  • 52
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie AH. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284(5756): 555-556. (Pubitemid 10070336)
    • (1980) Nature , vol.284 , Issue.5756 , pp. 555-556
    • Wyllie, A.H.1
  • 53
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
    • DOI 10.1126/science.1096645
    • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, Baehrecke EH, Lenardo MJ. 2004. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 304(5676):1500-1502. (Pubitemid 38720930)
    • (2004) Science , vol.304 , Issue.5676 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6    Baehrecke, E.H.7    Lenardo, M.J.8
  • 54
    • 35548930298 scopus 로고    scopus 로고
    • Specific inhibition of caspase-8 and -9 in CHO cells enhances cell viability in batch and fed-batch cultures
    • DOI 10.1016/j.ymben.2007.06.001, PII S109671760700033X
    • Yun CY, Liu S, Lim SF, Wang T, Chung BY, Jiat Teo J, Chuan KH, Soon AS, Goh KS, Song Z. 2007. Specific inhibition of caspase-8 and -9 in CHO cells enhances cell viability in batch and fed-batch cultures. Metab Eng 9(5-6):406-418. (Pubitemid 350016969)
    • (2007) Metabolic Engineering , vol.9 , Issue.5-6 , pp. 406-418
    • Yun, C.Y.1    Liu, S.2    Lim, S.F.3    Wang, T.4    Chung, B.Y.F.5    Jiat Teo, J.6    Chuan, K.H.7    Soon, A.S.C.8    Goh, K.S.9    Song, Z.10
  • 55
    • 44349182097 scopus 로고    scopus 로고
    • Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1
    • Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC. 2008. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. J Biol Chem 283(15):9580-9586.
    • (2008) J Biol Chem , vol.283 , Issue.15 , pp. 9580-9586
    • Zhai, D.1    Jin, C.2    Huang, Z.3    Satterthwait, A.C.4    Reed, J.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.