Hyperosmotic stress induces autophagy and apoptosis in recombinant chinese hamster ovary cell culture

Biotechnology and Bioengineering

Volumn 105, Issue 6, 2010, Pages 1187-1192

  Han, Young Kue ^a   Kim, Yeon Gu ^a   Kim, Jee Yon ^a   Lee, Gyun Min ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Apoptosis; Autophagy; Hyperosmotic stress; rCHO cells

Indexed keywords

APOPTOSIS; AUTOPHAGY; CASPASE-3; CASPASES; CELL LINES; CHINESE HAMSTER OVARY; CHINESE HAMSTER OVARY CELLS; CULTURE MEDIUM; HYPEROSMOTIC STRESS; NUTRIENT DEPLETION; NUTRIENT SOLUTION; OSMOLALITY; PROGRAMMED CELL DEATHS; WESTERN-BLOT ANALYSIS;

AMINO ACIDS; CELL DEATH; CONFOCAL MICROSCOPY; GLUCOSE; NUTRIENTS; SODIUM CHLORIDE;

CELL CULTURE;

CASPASE 3; CASPASE 7; GLUCOSE; GLUTAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CHO CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; DNA FRAGMENTATION; HYPEROSMOLALITY; HYPEROSMOTIC STRESS; NONHUMAN; NUTRITIONAL DEFICIENCY; WESTERN BLOTTING;

ANIMALS; ANTIBODIES; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; DNA FRAGMENTATION; ERYTHROPOIETIN, RECOMBINANT; GLUCOSE; MICROSCOPY, CONFOCAL; OSMOTIC PRESSURE; RECOMBINANT PROTEINS; SODIUM CHLORIDE; STRESS, PHYSIOLOGICAL;

CRICETULUS GRISEUS;

EID: 77951518297     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22643     Document Type: Article

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