N-β-Glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 15, 2011, Pages 4447-4450

  Rodríguez, Oscar M ^a   Maresca, Alfonso ^b   Témpera, Carlos A ^a   Bravo, Rodolfo D ^a   Colinas, Pedro A ^a   Supuran, Claudiu T ^b  

^a FACULTAD DE CIENCIAS EXACTAS   (Argentina)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cancer; Carbonic anhydrase; Glycosyl sulfamides; Targeted therapies

Indexed keywords

ANTINEOPLASTIC AGENT; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; GLYCOSIDE; SULFAMIDE DERIVATIVE; TOPIRAMATE;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPROTECTION REACTION; DRUG SELECTIVITY; DRUG TARGETING; ENZYME INHIBITION;

AMIDES; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; HUMANS; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960349940     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.06.031     Document Type: Article

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