-
2
-
-
0142054012
-
Apoptosis in heart failure and the senescent heart
-
Bernecker OY, Huq F, Heist EK, Podesser BK, and Hajjar RJ. Apoptosis in heart failure and the senescent heart. Cardiovasc Toxicol 3: 183-190, 2003.
-
(2003)
Cardiovasc Toxicol
, vol.3
, pp. 183-190
-
-
Bernecker, O.Y.1
Huq, F.2
Heist, E.K.3
Podesser, B.K.4
Hajjar, R.J.5
-
3
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski M, Horton T, Lott MT, Shoffner JM, Beal MF, and Wallace DC. Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nat Genet 2: 324-329, 1992.
-
(1992)
Nat Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
4
-
-
0033545382
-
Bcl-2 regulates amplification of caspase activation by cytochrome c
-
Cosulich SC, Savory PJ, and Clarke PR. Bcl-2 regulates amplification of caspase activation by cytochrome c. Curr Biol 9: 147-150, 1999.
-
(1999)
Curr Biol
, vol.9
, pp. 147-150
-
-
Cosulich, S.C.1
Savory, P.J.2
Clarke, P.R.3
-
5
-
-
0029815941
-
bfl-1, A bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity
-
D'Sa-Eipper C, Subramanian T, and Chinnadurai G. bfl-1, A bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. Cancer Res 56: 3879-3882, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 3879-3882
-
-
D'Sa-Eipper, C.1
Subramanian, T.2
Chinnadurai, G.3
-
6
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome C by direct inhibition of distinct caspases
-
Deveraux QL, Roy N, Stennicke HR, Van Arsdale T, Zhou Q, Srinivasula SM, Alnemri ES, Salvesen GS, and Reed JC. IAPs block apoptotic events induced by caspase-8 and cytochrome C by direct inhibition of distinct caspases. EMBO J 17: 2215-2223, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
Van Arsdale, T.4
Zhou, Q.5
Srinivasula, S.M.6
Alnemri, E.S.7
Salvesen, G.S.8
Reed, J.C.9
-
7
-
-
0033593230
-
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
-
Finucane DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG, and Green DR. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J Biol Chem 274: 2225-2233, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 2225-2233
-
-
Finucane, D.M.1
Bossy-Wetzel, E.2
Waterhouse, N.J.3
Cotter, T.G.4
Green, D.R.5
-
8
-
-
0036947077
-
Apoptosis in heart failure represents programmed cell survival, not death, of cardiomyocytes and likelihood of reverse remodeling
-
Haider N, Narula N, and Narula J. Apoptosis in heart failure represents programmed cell survival, not death, of cardiomyocytes and likelihood of reverse remodeling. J Card Fail 8: S512-S517, 2002.
-
(2002)
J Card Fail
, vol.8
-
-
Haider, N.1
Narula, N.2
Narula, J.3
-
9
-
-
0032053546
-
Differential expression of heat shock proteins in normal and failing human hearts
-
Knowlton AA, Kapadia S, Torre-Amione G, Durand JB, Bies R, Young J, and Mann DL. Differential expression of heat shock proteins in normal and failing human hearts. J Mol Cell Cardiol 30: 811-818, 1998.
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 811-818
-
-
Knowlton, A.A.1
Kapadia, S.2
Torre-Amione, G.3
Durand, J.B.4
Bies, R.5
Young, J.6
Mann, D.L.7
-
10
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
11
-
-
0028673454
-
Cardiovascular reserve capacity in healthy older humans
-
Lakatta EG. Cardiovascular reserve capacity in healthy older humans. Aging (Milano) 6: 213-223, 1994.
-
(1994)
Aging (Milano)
, vol.6
, pp. 213-223
-
-
Lakatta, E.G.1
-
12
-
-
0034075609
-
Upregulation of the Bcl-2 family of proteins in end stage heart failure
-
Latif N, Khan MA, Birks E, O'Farrell A, Westbrook J, Dunn MJ, and Yacoub MH. Upregulation of the Bcl-2 family of proteins in end stage heart failure. J Am Coll Cardiol 35: 1769-1777, 2000.
-
(2000)
J Am Coll Cardiol
, vol.35
, pp. 1769-1777
-
-
Latif, N.1
Khan, M.A.2
Birks, E.3
O'Farrell, A.4
Westbrook, J.5
Dunn, M.J.6
Yacoub, M.H.7
-
13
-
-
0031843553
-
Bcl-2 and Bax expression in adult rat hearts after coronary occlusion: Age-associated differences
-
Liu L, Azhar G, Gao W, Zhang X, and Wei JY. Bcl-2 and Bax expression in adult rat hearts after coronary occlusion: age-associated differences. Am J Physiol Regul Integr Camp Physiol 275: R315-R322, 1998.
-
(1998)
Am J Physiol Regul Integr Camp Physiol
, vol.275
-
-
Liu, L.1
Azhar, G.2
Gao, W.3
Zhang, X.4
Wei, J.Y.5
-
14
-
-
0032030309
-
Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing
-
Liu VW, Zhang C, and Nagley F. Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing. Nucleic Acids Res 26: 1268-1275, 1998.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1268-1275
-
-
Liu, V.W.1
Zhang, C.2
Nagley, F.3
-
15
-
-
0029816017
-
Primary pathogenic mtDNA mutations in multigeneration pedigrees with Leber hereditary optic neuropathy
-
Mackey DA, Oostra RJ, Rosenberg T, Nikoskelainen E, Bronte-Stewart J, Poulton J, Harding AE, Govan G, Bolhuis PA, and Norby S. Primary pathogenic mtDNA mutations in multigeneration pedigrees with Leber hereditary optic neuropathy. Am J Hum Genet 59: 481-485, 1996.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 481-485
-
-
Mackey, D.A.1
Oostra, R.J.2
Rosenberg, T.3
Nikoskelainen, E.4
Bronte-Stewart, J.5
Poulton, J.6
Harding, A.E.7
Govan, G.8
Bolhuis, P.A.9
Norby, S.10
-
16
-
-
0028271178
-
Age-related acute adriamycin cardiotoxicity in mice
-
Matsumura M, Nishioka K, Fujii T, Yoshibayashi M, Nozaki K, Nakata Y, Temma S, Ueda T, and Mikawa H. Age-related acute adriamycin cardiotoxicity in mice. J Mol Cell Cardiol 26: 699-905, 1994.
-
(1994)
J Mol Cell Cardiol
, vol.26
, pp. 699-905
-
-
Matsumura, M.1
Nishioka, K.2
Fujii, T.3
Yoshibayashi, M.4
Nozaki, K.5
Nakata, Y.6
Temma, S.7
Ueda, T.8
Mikawa, H.9
-
17
-
-
2942576595
-
Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A
-
Mott JL, Zhang D, Freeman JC, Mikolajczak P, Chang SW, and Zassenhaus HP. Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A. Biochem Biophys Res Commun 319: 1210-1215, 2004.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1210-1215
-
-
Mott, J.L.1
Zhang, D.2
Freeman, J.C.3
Mikolajczak, P.4
Chang, S.W.5
Zassenhaus, H.P.6
-
18
-
-
0035283326
-
Oxidative stress is not an obligate mediator of disease provoked by mitochondrial DNA mutations
-
Mott JL, Zhang D, Stevens M, Chang S, Denniger G, and Zassenhaus HP. Oxidative stress is not an obligate mediator of disease provoked by mitochondrial DNA mutations. Mutat Res 474: 35-45, 2001.
-
(2001)
Mutat Res
, vol.474
, pp. 35-45
-
-
Mott, J.L.1
Zhang, D.2
Stevens, M.3
Chang, S.4
Denniger, G.5
Zassenhaus, H.P.6
-
19
-
-
0027103991
-
Mitochondrial DNA mutation associated with aging and degenerative disease
-
Nagley P, Mackay IR, Baumer A, Maxwell RJ, Vaillant F, Wang ZX, Zhang C, and Linnane AW. Mitochondrial DNA mutation associated with aging and degenerative disease. Ann NY Acad Sci 673: 92-102, 1992.
-
(1992)
Ann NY Acad Sci
, vol.673
, pp. 92-102
-
-
Nagley, P.1
Mackay, I.R.2
Baumer, A.3
Maxwell, R.J.4
Vaillant, F.5
Wang, Z.X.6
Zhang, C.7
Linnane, A.W.8
-
20
-
-
0033529281
-
Apoptosis in heart failure: Release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy
-
Narula J, Pandey P, Arbustini E, Haider N, Narula N, Kolodgie FD, Dal Bello B, Semigran MJ, Bielsa-Masdeu A, Dec GW, Israels S, Ballester M, Virmani R, Saxena S, and Kharbanda S. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci USA 96: 8144-8149, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8144-8149
-
-
Narula, J.1
Pandey, P.2
Arbustini, E.3
Haider, N.4
Narula, N.5
Kolodgie, F.D.6
Dal Bello, B.7
Semigran, M.J.8
Bielsa-Masdeu, A.9
Dec, G.W.10
Israels, S.11
Ballester, M.12
Virmani, R.13
Saxena, S.14
Kharbanda, S.15
-
21
-
-
0033956449
-
The putative pore-forming domain of Bax regulates mitochondrial localization and interaction with Bcl-X(L)
-
Nouraini S, Six E, Matsuyama S, Krajewski S, and Reed JC. The putative pore-forming domain of Bax regulates mitochondrial localization and interaction with Bcl-X(L). Mol Cell Biol 20: 1604-1615, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1604-1615
-
-
Nouraini, S.1
Six, E.2
Matsuyama, S.3
Krajewski, S.4
Reed, J.C.5
-
22
-
-
0029010616
-
Mitochondrial DNA mutations associated with aging and degenerative diseases
-
Ozawa T. Mitochondrial DNA mutations associated with aging and degenerative diseases. Exp Gerontol 30: 269-290, 1995.
-
(1995)
Exp Gerontol
, vol.30
, pp. 269-290
-
-
Ozawa, T.1
-
23
-
-
0034643424
-
Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3
-
Pandey P, Farber R, Nakazawa A, Kumar S, Bharti A, Nalin C, Weichselbaum R, Kufe D, and Kharbanda S. Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene 19: 1975-1981, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 1975-1981
-
-
Pandey, P.1
Farber, R.2
Nakazawa, A.3
Kumar, S.4
Bharti, A.5
Nalin, C.6
Weichselbaum, R.7
Kufe, D.8
Kharbanda, S.9
-
24
-
-
0036081753
-
Cytochrome c release from mitochondria in the aging heart: A possible mechanism for apoptosis with age
-
Phaneuf S and Leeuwenburgh C. Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age. Am J Physiol Regul Integr Comp Physiol 282: R423-R430, 2002.
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.282
-
-
Phaneuf, S.1
Leeuwenburgh, C.2
-
25
-
-
0035355341
-
2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: Significance for the molecular mechanism of Bcl-2 action
-
2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J 20: 2690-2701, 2001.
-
(2001)
EMBO J
, vol.20
, pp. 2690-2701
-
-
Pinton, P.1
Ferrari, D.2
Rapizzi, E.3
Di Virgillo, F.4
Pozzan, T.5
Rizzuto, R.6
-
26
-
-
0036238915
-
The role of apoptosis in the normal aging brain, skeletal muscle, and heart
-
Pollack M, Phaneuf S, Dirks A, and Leeuwenburgh C. The role of apoptosis in the normal aging brain, skeletal muscle, and heart. Ann NY Acad Sci 959: 93-107, 2002.
-
(2002)
Ann NY Acad Sci
, vol.959
, pp. 93-107
-
-
Pollack, M.1
Phaneuf, S.2
Dirks, A.3
Leeuwenburgh, C.4
-
27
-
-
0344142396
-
Emerging roles of caspase-3 in apoptosis
-
Porter AG and Janicke RU. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6: 99-104, 1999.
-
(1999)
Cell Death Differ
, vol.6
, pp. 99-104
-
-
Porter, A.G.1
Janicke, R.U.2
-
28
-
-
0027207013
-
In-vivo and in-vitro mitochondrial membrane damages induced in mice by adriamycin and derivatives
-
Praet M and Ruysschaert JM. In-vivo and in-vitro mitochondrial membrane damages induced in mice by adriamycin and derivatives. Biochim Biophys Acta 1149: 79-85, 1993.
-
(1993)
Biochim Biophys Acta
, vol.1149
, pp. 79-85
-
-
Praet, M.1
Ruysschaert, J.M.2
-
29
-
-
0037028646
-
Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: Fragile balance of myocyte survival?
-
Scheubel RJ, Bartling B, Simm A, Silber RE, Drogaris K, Darmer D, and Holtz J. Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: fragile balance of myocyte survival? J Am Coll Cardiol 39: 481-488, 2002.
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 481-488
-
-
Scheubel, R.J.1
Bartling, B.2
Simm, A.3
Silber, R.E.4
Drogaris, K.5
Darmer, D.6
Holtz, J.7
-
30
-
-
1642463791
-
Leigh syndrome caused by mitochondrial DNA G13513A mutation: Frequency and clinical features in Japan
-
Sudo A, Honzawa S, Nonaka I, and Goto Y. Leigh syndrome caused by mitochondrial DNA G13513A mutation: frequency and clinical features in Japan. J Hum Genet 49: 92-96, 2004.
-
(2004)
J Hum Genet
, vol.49
, pp. 92-96
-
-
Sudo, A.1
Honzawa, S.2
Nonaka, I.3
Goto, Y.4
-
31
-
-
18044393158
-
Light microscopy and ultrastructure of blood vessels and heart
-
edited by Silver MD, Gotlieb AI, and Schoen FJ. New York: Churchill Livingstone
-
Veinot JP, Ghadially FN, and Walley VM. Light microscopy and ultrastructure of blood vessels and heart. In: Cardiovascular Pathology, edited by Silver MD, Gotlieb AI, and Schoen FJ. New York: Churchill Livingstone. 2001, p. 30-53.
-
(2001)
Cardiovascular Pathology
, pp. 30-53
-
-
Veinot, J.P.1
Ghadially, F.N.2
Walley, V.M.3
-
32
-
-
85047694494
-
A mechanistic role for cardiac myocyte apoptosis in heart failure
-
Wencker D, Chandra M, Nguyen K, Miao W, Garantziotis S, Factor SM, Shirani J, Armstrong RC, and Kitsis RN. A mechanistic role for cardiac myocyte apoptosis in heart failure. J Clin Invest 111: 1497-1504, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 1497-1504
-
-
Wencker, D.1
Chandra, M.2
Nguyen, K.3
Miao, W.4
Garantziotis, S.5
Factor, S.M.6
Shirani, J.7
Armstrong, R.C.8
Kitsis, R.N.9
-
33
-
-
0034667349
-
Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis
-
Zhang D, Mott JL, Chang SW, Denniger G, Feng Z, and Zassenhaus HP. Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis. Genomics 69: 151-161, 2000.
-
(2000)
Genomics
, vol.69
, pp. 151-161
-
-
Zhang, D.1
Mott, J.L.2
Chang, S.W.3
Denniger, G.4
Feng, Z.5
Zassenhaus, H.P.6
-
34
-
-
0037214525
-
Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy
-
Zhang D, Mott JL, Farrar P, Ryerse JS, Chang SW, Stevens M, Denniger G, and Zassenhaus HP. Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy. Cardiovasc Res 57: 147-157, 2003.
-
(2003)
Cardiovasc Res
, vol.57
, pp. 147-157
-
-
Zhang, D.1
Mott, J.L.2
Farrar, P.3
Ryerse, J.S.4
Chang, S.W.5
Stevens, M.6
Denniger, G.7
Zassenhaus, H.P.8
-
35
-
-
0035695645
-
Regulation of sodium-calcium exchange and mitochondrial energetics by Bcl-2 in the heart of transgenic mice
-
Zhu L, Yu Y, Chua BH, Ho YS, and Kuo TH. Regulation of sodium-calcium exchange and mitochondrial energetics by Bcl-2 in the heart of transgenic mice. J Mol Cell Cardiol 33: 2135-2144, 2001.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 2135-2144
-
-
Zhu, L.1
Yu, Y.2
Chua, B.H.3
Ho, Y.S.4
Kuo, T.H.5
-
36
-
-
0037276292
-
Apoptosis of myocytes and proliferation markers as prognostic factors in end-stage dilated cardiomyopathy
-
Zorc M, Vraspir-Porenta O, Zorc-Pleskovic R, Radovanovic N, and Petrovic D. Apoptosis of myocytes and proliferation markers as prognostic factors in end-stage dilated cardiomyopathy. Cardiovasc Pathol 12: 36-39, 2003.
-
(2003)
Cardiovasc Pathol
, vol.12
, pp. 36-39
-
-
Zorc, M.1
Vraspir-Porenta, O.2
Zorc-Pleskovic, R.3
Radovanovic, N.4
Petrovic, D.5
|