The -980C/G polymorphism in APH-1A promoter confers risk of Alzheimer's disease

Aging Cell

Volumn 10, Issue 4, 2011, Pages 711-719

  Qin, Wei ^a   Jia, Longfei ^a   Zhou, Aihong ^a   Zuo, Xiumei ^a   Cheng, Zhe ^a   Wang, Fen ^a   Shi, Fudong ^b   Jia, Jianping ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

secretase; Alzheimer's disease; APH 1A gene; Gene expression; Polymorphism; Yin Yang 1

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA SECRETASE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ALLELE; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTERIOR PHARYNX DEFECTIVE 1A GENE; ARTICLE; CELL STRAIN HEK293; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME ASSAY; GEL MOBILITY SHIFT ASSAY; GENE; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; RISK; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BASE SEQUENCE; FEMALE; HEK293 CELLS; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; RISK; RISK FACTORS; YY1 TRANSCRIPTION FACTOR;

EID: 79960296149     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00708.x     Document Type: Article

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