메뉴 건너뛰기




Volumn 455, Issue 2, 2009, Pages 101-104

Association between promoter polymorphisms in anterior pharynx-defective-1a and sporadic Alzheimer's disease in the North Chinese Han population

Author keywords

Alzheimer's disease; APH 1a; Polymorphism; Promoter

Indexed keywords

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; APOLIPOPROTEIN E4;

EID: 63649103805     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.02.015     Document Type: Article
Times cited : (6)

References (22)
  • 2
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H., and Braak E. Neuropathological stageing of Alzheimer-related changes. Acta. Neuropathol. 82 (1991) 239-259
    • (1991) Acta. Neuropathol. , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 3
    • 0037066084 scopus 로고    scopus 로고
    • Endoproteolysis of presenilin in vitro: inhibition by gamma-secretase inhibitors
    • Campbell W.A., Iskandar M.K., Reed M.L., and Xia W. Endoproteolysis of presenilin in vitro: inhibition by gamma-secretase inhibitors. Biochemistry 41 (2002) 3372-3379
    • (2002) Biochemistry , vol.41 , pp. 3372-3379
    • Campbell, W.A.1    Iskandar, M.K.2    Reed, M.L.3    Xia, W.4
  • 4
    • 0031897917 scopus 로고    scopus 로고
    • Functional analysis of the Huntington's disease (HD) gene promoter
    • Coles R., Caswell R., and Rubinsztein D.C. Functional analysis of the Huntington's disease (HD) gene promoter. Hum. Mol. Genet. 7 (1998) 791-800
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 791-800
    • Coles, R.1    Caswell, R.2    Rubinsztein, D.C.3
  • 5
    • 0037431082 scopus 로고    scopus 로고
    • Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex
    • De Strooper B. Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex. Neuron 38 (2003) 9-12
    • (2003) Neuron , vol.38 , pp. 9-12
    • De Strooper, B.1
  • 7
    • 0037154158 scopus 로고    scopus 로고
    • APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos
    • Goutte C., Tsunozaki M., Hale V.A., and Priess J.R. APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 775-779
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 775-779
    • Goutte, C.1    Tsunozaki, M.2    Hale, V.A.3    Priess, J.R.4
  • 8
    • 0038360879 scopus 로고    scopus 로고
    • Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex
    • Hu Y., and Fortini M.E. Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex. J. Cell. Biol. 161 (2003) 685-690
    • (2003) J. Cell. Biol. , vol.161 , pp. 685-690
    • Hu, Y.1    Fortini, M.E.2
  • 9
    • 2942604376 scopus 로고    scopus 로고
    • The gamma-secretase complex: machinery for intramembrane proteolysis
    • Iwatsubo T. The gamma-secretase complex: machinery for intramembrane proteolysis. Curr. Opin. Neurobiol. 14 (2004) 379-383
    • (2004) Curr. Opin. Neurobiol. , vol.14 , pp. 379-383
    • Iwatsubo, T.1
  • 11
    • 0034984156 scopus 로고    scopus 로고
    • The -48 C/T polymorphism in the presenilin 1 promoter is associated with an increased risk of developing Alzheimer's disease and an increased Abeta load in brain
    • Lambert J.C., Mann D.M., Harris J.M., Chartier-Harlin M.C., Cumming A., Coates J., Lemmon H., StClair D., Iwatsubo T., and Lendon C. The -48 C/T polymorphism in the presenilin 1 promoter is associated with an increased risk of developing Alzheimer's disease and an increased Abeta load in brain. J. Med. Genet. 38 (2001) 353-355
    • (2001) J. Med. Genet. , vol.38 , pp. 353-355
    • Lambert, J.C.1    Mann, D.M.2    Harris, J.M.3    Chartier-Harlin, M.C.4    Cumming, A.5    Coates, J.6    Lemmon, H.7    StClair, D.8    Iwatsubo, T.9    Lendon, C.10
  • 13
    • 37549040895 scopus 로고    scopus 로고
    • Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer's disease
    • Lv H., Jia L., and Jia J. Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer's disease. Neurobiol. Aging 29 (2008) 194-202
    • (2008) Neurobiol. Aging , vol.29 , pp. 194-202
    • Lv, H.1    Jia, L.2    Jia, J.3
  • 14
    • 12144250683 scopus 로고    scopus 로고
    • APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development
    • Ma G., Li T., Price D.L., and Wong P.C. APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development. J. Neurosci. 25 (2005) 192-198
    • (2005) J. Neurosci. , vol.25 , pp. 192-198
    • Ma, G.1    Li, T.2    Price, D.L.3    Wong, P.C.4
  • 15
    • 16844364135 scopus 로고    scopus 로고
    • Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions
    • Niimura M., Isoo N., Takasugi N., Tsuruoka M., Ui-Tei K., Saigo K., Morohashi Y., Tomita T., and Iwatsubo T. Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions. J. Biol. Chem. 280 (2005) 12967-12975
    • (2005) J. Biol. Chem. , vol.280 , pp. 12967-12975
    • Niimura, M.1    Isoo, N.2    Takasugi, N.3    Tsuruoka, M.4    Ui-Tei, K.5    Saigo, K.6    Morohashi, Y.7    Tomita, T.8    Iwatsubo, T.9
  • 16
    • 0042827346 scopus 로고    scopus 로고
    • Association analysis between anterior-pharynx defective-1 genes polymorphisms and Alzheimer's disease
    • Poli M., Gatta L.B., Archetti S., Padovani A., Albertini A., and Finazzi D. Association analysis between anterior-pharynx defective-1 genes polymorphisms and Alzheimer's disease. Neurosci. Lett. 350 (2003) 77-80
    • (2003) Neurosci. Lett. , vol.350 , pp. 77-80
    • Poli, M.1    Gatta, L.B.2    Archetti, S.3    Padovani, A.4    Albertini, A.5    Finazzi, D.6
  • 17
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: genes, proteins, and therapy
    • Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81 (2001) 741-766
    • (2001) Physiol. Rev. , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 19
    • 0028218871 scopus 로고
    • Neuropathological changes in Alzheimer disease
    • Terry R.D. Neuropathological changes in Alzheimer disease. Prog. Brain Res. 101 (1994) 383-390
    • (1994) Prog. Brain Res. , vol.101 , pp. 383-390
    • Terry, R.D.1
  • 20
    • 0002722479 scopus 로고
    • Linkage disequilibrium between alleles at marker loci
    • The John Hopkins University Press, Baltimore, MD pp. 188-198
    • Terwilliger J.D., and Ott J. Linkage disequilibrium between alleles at marker loci. Handbook of Human Genetic Linkage (1994), The John Hopkins University Press, Baltimore, MD pp. 188-198
    • (1994) Handbook of Human Genetic Linkage
    • Terwilliger, J.D.1    Ott, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.