Formation of the base modification 8-hydroxyl-2'-deoxyguanosine and DNA fragmentation following seizures induced by systemic kainic acid in the rat

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 302-309

  Lan, Jing ^a   Henshall, David C ^a   Simon, Roger P ^a   Chen, Jun ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Double stranded DNA breaks; HPLC; Kainic acid; Oxidative stress; Rat; Single stranded DNA breaks

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DNA FRAGMENT; KAINIC ACID;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; DNA NICK TRANSLATION; ELECTROCHEMICAL ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SEIZURE;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA FRAGMENTATION; GENETIC TECHNIQUES; IN SITU NICK-END LABELING; KAINIC ACID; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES;

ANIMALIA;

EID: 0033964860     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740302.x     Document Type: Article

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