-
1
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., Leisten J.C., Motiwala A., Pierce S., Satoh Y., Bhagwat S.S., Manning A.M., and Anderson D.W. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 13681-13686
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
Bhagwat, S.S.11
Manning, A.M.12
Anderson, D.W.13
-
3
-
-
0031918223
-
BCL-2 family: regulators of cell death
-
Chao D.T., and Korsmeyer S.J. BCL-2 family: regulators of cell death. Annu. Rev. Immunol. 16 (1998) 395-419
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
4
-
-
2942517676
-
Oxidative neuronal injury; the dark side of ERK1/2
-
Chu C.T., Levinthal D.J., Kulich S.M., Chalovich E.M., and DeFranco D.B. Oxidative neuronal injury; the dark side of ERK1/2. Eur. J. Biochem. 271 (2004) 2060-2066
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 2060-2066
-
-
Chu, C.T.1
Levinthal, D.J.2
Kulich, S.M.3
Chalovich, E.M.4
DeFranco, D.B.5
-
5
-
-
0027686249
-
Oxidative stress, glutamate,and neurodegenerative disorders
-
Coyle J.T., and Puttfarcken P. Oxidative stress, glutamate,and neurodegenerative disorders. Science 262 (1993) 689-695
-
(1993)
Science
, vol.262
, pp. 689-695
-
-
Coyle, J.T.1
Puttfarcken, P.2
-
6
-
-
0035167270
-
The role of Bax in glutamate-induced nerve cell death
-
Dargusch R., Piasecki D., Tan S., Liu Y., and Schubert D. The role of Bax in glutamate-induced nerve cell death. J. Neurosci. 76 (2001) 295-301
-
(2001)
J. Neurosci.
, vol.76
, pp. 295-301
-
-
Dargusch, R.1
Piasecki, D.2
Tan, S.3
Liu, Y.4
Schubert, D.5
-
7
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Van Dyk D.E., Pitts W.J., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., and Trzaskos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273 (1998) 18623-18632
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
8
-
-
0344348821
-
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
-
Hu Y., Benedict M.A., Ding L., and Núñez G. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J. 18 (1999) 3586-3595
-
(1999)
EMBO J.
, vol.18
, pp. 3586-3595
-
-
Hu, Y.1
Benedict, M.A.2
Ding, L.3
Núñez, G.4
-
9
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee J.C., Laydon J.T., McDonnell P.C., Gallagher T.F., Kumar S., Green D., McNulty D., Blumenthal M.J., Heys J.R., Landvatter S.W., et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372 (1994) 739-746
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
10
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., and Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91 (1997) 479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
11
-
-
0024678458
-
Glutamate toxicity in neuronal cell line involves inhibition of cystine transport leading to oxidative stress
-
Murphy T.H., Miyamoto M., Sastre A., Schnaar R.L., and Coyle J.T. Glutamate toxicity in neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2 (1989) 1547-1558
-
(1989)
Neuron
, vol.2
, pp. 1547-1558
-
-
Murphy, T.H.1
Miyamoto, M.2
Sastre, A.3
Schnaar, R.L.4
Coyle, J.T.5
-
12
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
-
Pearson G., Robinson F., Gibson T.B., Xu B., Karandikar M., Berman K., and Cobb M.H. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22 (2001) 153-183
-
(2001)
Endocr. Rev.
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Gibson, T.B.3
Xu, B.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
13
-
-
0028324464
-
Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium and phospholipids-binding proteins
-
Raynal P., and Pollard H.B. Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium and phospholipids-binding proteins. Biochim. Biophys. Acta 1197 (1994) 63-93
-
(1994)
Biochim. Biophys. Acta
, vol.1197
, pp. 63-93
-
-
Raynal, P.1
Pollard, H.B.2
-
14
-
-
0033539067
-
Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation
-
Sahara S., Aoto M., Eguchi Y., Imamoto N., Yoneda Y., and Tsujimoto Y. Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation. Nature 401 (1999) 168-173
-
(1999)
Nature
, vol.401
, pp. 168-173
-
-
Sahara, S.1
Aoto, M.2
Eguchi, Y.3
Imamoto, N.4
Yoneda, Y.5
Tsujimoto, Y.6
-
15
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signaling-regulation kinase (ASK)1
-
Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., Kawabata M., Miyazono K., and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signaling-regulation kinase (ASK)1. EMBO J. 17 (1998) 2596-2606
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
16
-
-
0031813589
-
Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells
-
Tan S., Wood M., and Maher P. Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. J. Neurochem. 71 (1998) 95-105
-
(1998)
J. Neurochem.
, vol.71
, pp. 95-105
-
-
Tan, S.1
Wood, M.2
Maher, P.3
-
17
-
-
0032526940
-
The regulation of reactive oxygen species production during programmed cell death
-
Tan S., Sagara Y., Liu Y., Maher P., and Schubert D. The regulation of reactive oxygen species production during programmed cell death. J. Cell Biol. 141 (1998) 1423-1432
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1423-1432
-
-
Tan, S.1
Sagara, Y.2
Liu, Y.3
Maher, P.4
Schubert, D.5
-
18
-
-
0035756761
-
Oxitosis: a novel form of programmed cell death
-
Tan S., Schubert D., and Maher P. Oxitosis: a novel form of programmed cell death. Cerr. Top. Med. Chem. 1 (2001) 497-506
-
(2001)
Cerr. Top. Med. Chem.
, vol.1
, pp. 497-506
-
-
Tan, S.1
Schubert, D.2
Maher, P.3
-
19
-
-
0029945204
-
A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherant cells in culture
-
van Engeland M., Ramaekers F.C., Schutte B., and Reutelingsperger C. A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherant cells in culture. Cytometry 24 (1996) 131-139
-
(1996)
Cytometry
, vol.24
, pp. 131-139
-
-
van Engeland, M.1
Ramaekers, F.C.2
Schutte, B.3
Reutelingsperger, C.4
-
20
-
-
13644270245
-
Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity
-
van Leyen K., Siddiq A., Ratan R.R., and Lo E.H. Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity. J. Neurochem. 92 (2005) 824-830
-
(2005)
J. Neurochem.
, vol.92
, pp. 824-830
-
-
van Leyen, K.1
Siddiq, A.2
Ratan, R.R.3
Lo, E.H.4
-
21
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Anexin V
-
Vermes I., Haanen C., Steffens-Nakken H., and Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Anexin V. J. Immunol. Methods 184 (1995) 39-51
-
(1995)
J. Immunol. Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
22
-
-
33747012605
-
Glutamate-induced apotosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis-inducing factor (AIF) and this process is inhibited by equine estrogens
-
Zhang Y.M., and Bhavnani B.R. Glutamate-induced apotosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis-inducing factor (AIF) and this process is inhibited by equine estrogens. BMC Neurosci. 7 (2006) 49
-
(2006)
BMC Neurosci.
, vol.7
, pp. 49
-
-
Zhang, Y.M.1
Bhavnani, B.R.2
|