-
1
-
-
79960150310
-
-
Food and Drug Administration. Drug interaction studies-Study design, data analysis, and implications for dosing and labeling. Guidance for industry (draft).
-
Food and Drug Administration. 2006. Drug interaction studies-Study design, data analysis, and implications for dosing and labeling. Guidance for industry (draft).
-
(2006)
-
-
-
2
-
-
79960136136
-
-
European Medicines Agency. Guideline on the investigation of drug interactions (draft).
-
European Medicines Agency. 2010. Guideline on the investigation of drug interactions (draft).
-
(2010)
-
-
-
3
-
-
0024593744
-
Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
-
Hidalgo IJ, Raub TJ, Borchardt RT. 1989. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96:736-749.
-
(1989)
Gastroenterology
, vol.96
, pp. 736-749
-
-
Hidalgo, I.J.1
Raub, T.J.2
Borchardt, R.T.3
-
4
-
-
36348992468
-
Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR
-
Maubon N, Le VM, Fossati L, Audry M, Le FE, Bolze S, Fardel O. 2007. Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR. Fundam Clin Pharmacol 21:659-663.
-
(2007)
Fundam Clin Pharmacol
, vol.21
, pp. 659-663
-
-
Maubon, N.1
Le, V.M.2
Fossati, L.3
Audry, M.4
Le, F.E.5
Bolze, S.6
Fardel, O.7
-
5
-
-
56149087140
-
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories
-
Hayeshi R, Hilgendorf C, Artursson P, Augustijns P, Brodin B, Dehertogh P, Fisher K, Fossati L, Hovenkamp E, Korjamo T, Masungi C, Maubon N, Mols R, Mullertz A, Monkkonen J, O'Driscoll C, Oppers-Tiemissen HM, Ragnarsson EG, Rooseboom M, Ungell AL. 2008. Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories. Eur J Pharm Sci 35:383-396.
-
(2008)
Eur J Pharm Sci
, vol.35
, pp. 383-396
-
-
Hayeshi, R.1
Hilgendorf, C.2
Artursson, P.3
Augustijns, P.4
Brodin, B.5
Dehertogh, P.6
Fisher, K.7
Fossati, L.8
Hovenkamp, E.9
Korjamo, T.10
Masungi, C.11
Maubon, N.12
Mols, R.13
Mullertz, A.14
Monkkonen, J.15
O'Driscoll, C.16
Oppers-Tiemissen, H.M.17
Ragnarsson, E.G.18
Rooseboom, M.19
Ungell, A.L.20
more..
-
6
-
-
44349116738
-
The Caco-2 cell monolayer: Usefulness and limitations
-
Sun H, Chow EC, Liu S, Du Y, Pang KS. 2008. The Caco-2 cell monolayer: Usefulness and limitations. Expert Opin Drug Metab Toxicol 4:395-411.
-
(2008)
Expert Opin Drug Metab Toxicol
, vol.4
, pp. 395-411
-
-
Sun, H.1
Chow, E.C.2
Liu, S.3
Du, Y.4
Pang, K.S.5
-
7
-
-
71049160053
-
Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs
-
Ahlin G, Hilgendorf C, Karlsson J, Szigyarto CA, Uhlen M, Artursson P. 2009. Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs. Drug Metab Dispos 37:2275-2283.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 2275-2283
-
-
Ahlin, G.1
Hilgendorf, C.2
Karlsson, J.3
Szigyarto, C.A.4
Uhlen, M.5
Artursson, P.6
-
8
-
-
77649216536
-
Membrane transporters in drug development
-
Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. 2010. Membrane transporters in drug development. Nat Rev Drug Discov 9:215-236.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
Chu, X.6
Dahlin, A.7
Evers, R.8
Fischer, V.9
Hillgren, K.M.10
Hoffmaster, K.A.11
Ishikawa, T.12
Keppler, D.13
Kim, R.B.14
Lee, C.A.15
Niemi, M.16
Polli, J.W.17
Sugiyama, Y.18
Swaan, P.W.19
Ware, J.A.20
Wright, S.H.21
Yee, S.W.22
Zamek-Gliszczynski, M.J.23
Zhang, L.24
more..
-
9
-
-
34249038460
-
Evaluation of drug-transporter interactions using in vitro and in vivo models
-
Xia CQ, Milton MN, Gan LS. 2007. Evaluation of drug-transporter interactions using in vitro and in vivo models. Curr Drug Metab 8:341-363.
-
(2007)
Curr Drug Metab
, vol.8
, pp. 341-363
-
-
Xia, C.Q.1
Milton, M.N.2
Gan, L.S.3
-
10
-
-
60749089233
-
Permeability-In vitro assays for assessing drug transporter activity
-
Jin H, Di L. 2008. Permeability-In vitro assays for assessing drug transporter activity. Curr Drug Metab 9:911-920.
-
(2008)
Curr Drug Metab
, vol.9
, pp. 911-920
-
-
Jin, H.1
Di, L.2
-
11
-
-
34547169521
-
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
-
Hilgendorf C, Ahlin G, Seithel A, Artursson P, Ungell AL, Karlsson J. 2007. Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines. Drug Metab Dispos 35:1333-1340.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1333-1340
-
-
Hilgendorf, C.1
Ahlin, G.2
Seithel, A.3
Artursson, P.4
Ungell, A.L.5
Karlsson, J.6
-
12
-
-
0038637144
-
Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane
-
Kobayashi D, Nozawa T, Imai K, Nezu J, Tsuji A, Tamai I. 2003. Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. J Pharmacol Exp Ther 306:703-708.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 703-708
-
-
Kobayashi, D.1
Nozawa, T.2
Imai, K.3
Nezu, J.4
Tsuji, A.5
Tamai, I.6
-
13
-
-
48749112588
-
Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
-
Hagenbuch B, Gui C. 2008. Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family. Xenobiotica 38:778-801.
-
(2008)
Xenobiotica
, vol.38
, pp. 778-801
-
-
Hagenbuch, B.1
Gui, C.2
-
14
-
-
33645119837
-
The solute carrier family SLC10: More than a family of bile acid transporters regarding function and phylogenetic relationships
-
Geyer J, Wilke T, Petzinger E. 2006. The solute carrier family SLC10: More than a family of bile acid transporters regarding function and phylogenetic relationships. Naunyn Schmiedebergs Arch Pharmacol 372:413-431.
-
(2006)
Naunyn Schmiedebergs Arch Pharmacol
, vol.372
, pp. 413-431
-
-
Geyer, J.1
Wilke, T.2
Petzinger, E.3
-
15
-
-
33745831231
-
Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters
-
Choudhuri S, Klaassen CD. 2006. Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters. Int J Toxicol 25:231-259.
-
(2006)
Int J Toxicol
, vol.25
, pp. 231-259
-
-
Choudhuri, S.1
Klaassen, C.D.2
-
16
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, Ross DD. 1998. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A 95:15665-15670.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
Ross, D.D.7
-
17
-
-
27644480743
-
Role of the breast cancer resistance protein (ABCG2) in drug transport
-
Mao Q, Unadkat JD. 2005. Role of the breast cancer resistance protein (ABCG2) in drug transport. AAPS J 7:E118-E133.
-
(2005)
AAPS J
, vol.7
-
-
Mao, Q.1
Unadkat, J.D.2
-
18
-
-
0034119967
-
Expression and localization of multidrug resistant protein mrp2 in rat small intestine
-
Mottino AD, Hoffman T, Jennes L, Vore M. 2000. Expression and localization of multidrug resistant protein mrp2 in rat small intestine. J Pharmacol Exp Ther 293:717-723.
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 717-723
-
-
Mottino, A.D.1
Hoffman, T.2
Jennes, L.3
Vore, M.4
-
19
-
-
14844291348
-
The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter
-
Dawson PA, Hubbert M, Haywood J, Craddock AL, Zerangue N, Christian WV, Ballatori N. 2005. The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. J Biol Chem 280:6960-6968.
-
(2005)
J Biol Chem
, vol.280
, pp. 6960-6968
-
-
Dawson, P.A.1
Hubbert, M.2
Haywood, J.3
Craddock, A.L.4
Zerangue, N.5
Christian, W.V.6
Ballatori, N.7
-
20
-
-
30844460667
-
OSTalpha-OSTbeta: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia
-
Ballatori N, Christian WV, Lee JY, Dawson PA, Soroka CJ, Boyer JL, Madejczyk MS, Li N. 2005. OSTalpha-OSTbeta: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology 42:1270-1279.
-
(2005)
Hepatology
, vol.42
, pp. 1270-1279
-
-
Ballatori, N.1
Christian, W.V.2
Lee, J.Y.3
Dawson, P.A.4
Soroka, C.J.5
Boyer, J.L.6
Madejczyk, M.S.7
Li, N.8
-
21
-
-
0031838805
-
cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)
-
Kiuchi Y, Suzuki H, Hirohashi T, Tyson CA, Sugiyama Y. 1998. cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3). FEBS Lett 433:149-152.
-
(1998)
FEBS Lett
, vol.433
, pp. 149-152
-
-
Kiuchi, Y.1
Suzuki, H.2
Hirohashi, T.3
Tyson, C.A.4
Sugiyama, Y.5
-
22
-
-
33748887871
-
Caco-2 cell permeability assays to measure drug absorption
-
van Breemen RB, Li Y. 2005. Caco-2 cell permeability assays to measure drug absorption. Expert Opin Drug Metab Toxicol 1:175-185.
-
(2005)
Expert Opin Drug Metab Toxicol
, vol.1
, pp. 175-185
-
-
van Breemen, R.B.1
Li, Y.2
-
23
-
-
0035286778
-
Caco-2 monolayers in experimental and theoretical predictions of drug transport
-
Artursson P, Palm K, Luthman K. 2001. Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv Drug Deliv Rev 46:27-43.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 27-43
-
-
Artursson, P.1
Palm, K.2
Luthman, K.3
-
24
-
-
23944475903
-
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin
-
Hirano M, Maeda K, Matsushima S, Nozaki Y, Kusuhara H, Sugiyama Y. 2005. Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. Mol Pharmacol 68:800-807.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 800-807
-
-
Hirano, M.1
Maeda, K.2
Matsushima, S.3
Nozaki, Y.4
Kusuhara, H.5
Sugiyama, Y.6
-
25
-
-
34547178337
-
Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3
-
Noe J, Portmann R, Brun ME, Funk C. 2007. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. Drug Metab Dispos 35:1308-1314.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1308-1314
-
-
Noe, J.1
Portmann, R.2
Brun, M.E.3
Funk, C.4
-
26
-
-
70350140380
-
Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter
-
Zheng X, Ekins S, Raufman JP, Polli JE. 2009. Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter. Mol Pharm 6:1591-1603.
-
(2009)
Mol Pharm
, vol.6
, pp. 1591-1603
-
-
Zheng, X.1
Ekins, S.2
Raufman, J.P.3
Polli, J.E.4
-
27
-
-
33847325257
-
Taurocholate and taurodeoxycholate: Gel formation and protonation constants
-
Antonilli M, Bottari E, Festa MR. 2007. Taurocholate and taurodeoxycholate: Gel formation and protonation constants. Ann Chim 97:39-48.
-
(2007)
Ann Chim
, vol.97
, pp. 39-48
-
-
Antonilli, M.1
Bottari, E.2
Festa, M.R.3
-
28
-
-
41749092024
-
Modeling and prediction (correction) of partition coefficients of bile acids and their derivatives by multivariate regression methods
-
Sarbu C, Onisor C, Posa M, Kevresan S, Kuhajda K. 2008. Modeling and prediction (correction) of partition coefficients of bile acids and their derivatives by multivariate regression methods. Talanta 75:651-657.
-
(2008)
Talanta
, vol.75
, pp. 651-657
-
-
Sarbu, C.1
Onisor, C.2
Posa, M.3
Kevresan, S.4
Kuhajda, K.5
-
29
-
-
34547196949
-
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members
-
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. 2007. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem 282:23841-23853.
-
(2007)
J Biol Chem
, vol.282
, pp. 23841-23853
-
-
Kaler, G.1
Truong, D.M.2
Khandelwal, A.3
Nagle, M.4
Eraly, S.A.5
Swaan, P.W.6
Nigam, S.K.7
-
30
-
-
67349227126
-
Impact of carriers in oral absorption: Permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide
-
Gram LK, Rist GM, Lennernas H, Steffansen B. 2009. Impact of carriers in oral absorption: Permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide. Eur J Pharm Sci 37:378-386.
-
(2009)
Eur J Pharm Sci
, vol.37
, pp. 378-386
-
-
Gram, L.K.1
Rist, G.M.2
Lennernas, H.3
Steffansen, B.4
-
31
-
-
0021739393
-
Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem
-
Hofmann AF, Roda A. 1984. Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem. J Lipid Res 25:1477-1489.
-
(1984)
J Lipid Res
, vol.25
, pp. 1477-1489
-
-
Hofmann, A.F.1
Roda, A.2
-
32
-
-
0020626591
-
The influence of bile salt structure on self-association in aqueous solutions
-
Roda A, Hofmann AF, Mysels KJ. 1983. The influence of bile salt structure on self-association in aqueous solutions. J Biol Chem 258:6362-6370.
-
(1983)
J Biol Chem
, vol.258
, pp. 6362-6370
-
-
Roda, A.1
Hofmann, A.F.2
Mysels, K.J.3
-
33
-
-
0032480901
-
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach
-
Winiwarter S, Bonham NM, Ax F, Hallberg A, Lennernas H, Karlen A. 1998. Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach. J Med Chem 41:4939-4949.
-
(1998)
J Med Chem
, vol.41
, pp. 4939-4949
-
-
Winiwarter, S.1
Bonham, N.M.2
Ax, F.3
Hallberg, A.4
Lennernas, H.5
Karlen, A.6
-
34
-
-
33751003834
-
Presentation of a structurally diverse and commercially available drug data set for correlation and benchmarking studies
-
Skold C, Winiwarter S, Wernevik J, Bergstrom F, Engstrom L, Allen R, Box K, Comer J, Mole J, Hallberg A, Lennernas H, Lundstedt T, Ungell AL, Karlen A. 2006. Presentation of a structurally diverse and commercially available drug data set for correlation and benchmarking studies. J Med Chem 49:6660-6671.
-
(2006)
J Med Chem
, vol.49
, pp. 6660-6671
-
-
Skold, C.1
Winiwarter, S.2
Wernevik, J.3
Bergstrom, F.4
Engstrom, L.5
Allen, R.6
Box, K.7
Comer, J.8
Mole, J.9
Hallberg, A.10
Lennernas, H.11
Lundstedt, T.12
Ungell, A.L.13
Karlen, A.14
-
35
-
-
42649102984
-
Application and limitation of inhibitors in drug-transporter interactions studies
-
Wang Q, Strab R, Kardos P, Ferguson C, Li J, Owen A, Hidalgo IJ. 2008. Application and limitation of inhibitors in drug-transporter interactions studies. Int J Pharm 356:12-18.
-
(2008)
Int J Pharm
, vol.356
, pp. 12-18
-
-
Wang, Q.1
Strab, R.2
Kardos, P.3
Ferguson, C.4
Li, J.5
Owen, A.6
Hidalgo, I.J.7
-
36
-
-
0025358551
-
Transport of bile acids in a human intestinal epithelial cell line, Caco-2
-
Hidalgo IJ, Borchardt RT. 1990. Transport of bile acids in a human intestinal epithelial cell line, Caco-2. Biochim Biophys Acta 1035:97-103.
-
(1990)
Biochim Biophys Acta
, vol.1035
, pp. 97-103
-
-
Hidalgo, I.J.1
Borchardt, R.T.2
-
37
-
-
0025189818
-
Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier
-
Wilson G, Hassan IF, Dix CJ, Williamson I, Shah R, Mackay M, Artursson P. 1990. Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier. J Control Release 11:25-40.
-
(1990)
J Control Release
, vol.11
, pp. 25-40
-
-
Wilson, G.1
Hassan, I.F.2
Dix, C.J.3
Williamson, I.4
Shah, R.5
Mackay, M.6
Artursson, P.7
-
38
-
-
0031916146
-
Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter
-
Craddock AL, Love MW, Daniel RW, Kirby LC, Walters HC, Wong MH, Dawson PA. 1998. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. Am J Physiol 274:G157-G169.
-
(1998)
Am J Physiol
, vol.274
-
-
Craddock, A.L.1
Love, M.W.2
Daniel, R.W.3
Kirby, L.C.4
Walters, H.C.5
Wong, M.H.6
Dawson, P.A.7
-
39
-
-
33746048844
-
Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells
-
Sai Y, Kaneko Y, Ito S, Mitsuoka K, Kato Y, Tamai I, Artursson P, Tsuji A. 2006. Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells. Drug Metab Dispos 34:1423-1431.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1423-1431
-
-
Sai, Y.1
Kaneko, Y.2
Ito, S.3
Mitsuoka, K.4
Kato, Y.5
Tamai, I.6
Artursson, P.7
Tsuji, A.8
-
40
-
-
1642457252
-
Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human
-
Nozawa T, Imai K, Nezu J, Tsuji A, Tamai I. 2004. Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J Pharmacol Exp Ther 308:438-445.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 438-445
-
-
Nozawa, T.1
Imai, K.2
Nezu, J.3
Tsuji, A.4
Tamai, I.5
-
41
-
-
33745243715
-
Drug-drug interaction between pitavastatin and various drugs via OATP1B1
-
Hirano M, Maeda K, Shitara Y, Sugiyama Y. 2006. Drug-drug interaction between pitavastatin and various drugs via OATP1B1. Drug Metab Dispos 34:1229-1236.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1229-1236
-
-
Hirano, M.1
Maeda, K.2
Shitara, Y.3
Sugiyama, Y.4
-
42
-
-
34547124598
-
Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6)
-
Geyer J, Doring B, Meerkamp K, Ugele B, Bakhiya N, Fernandes CF, Godoy JR, Glatt H, Petzinger E. 2007. Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6). J Biol Chem 282:19728-19741.
-
(2007)
J Biol Chem
, vol.282
, pp. 19728-19741
-
-
Geyer, J.1
Doring, B.2
Meerkamp, K.3
Ugele, B.4
Bakhiya, N.5
Fernandes, C.F.6
Godoy, J.R.7
Glatt, H.8
Petzinger, E.9
-
43
-
-
0041344702
-
Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta
-
Seward DJ, Koh AS, Boyer JL, Ballatori N. 2003. Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta. J Biol Chem 278:27473-27482.
-
(2003)
J Biol Chem
, vol.278
, pp. 27473-27482
-
-
Seward, D.J.1
Koh, A.S.2
Boyer, J.L.3
Ballatori, N.4
-
44
-
-
0034709561
-
Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family
-
Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, Tsuji A. 2000. Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem Biophys Res Commun 273:251-260.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 251-260
-
-
Tamai, I.1
Nezu, J.2
Uchino, H.3
Sai, Y.4
Oku, A.5
Shimane, M.6
Tsuji, A.7
-
45
-
-
0242497239
-
Molecular characterization of human and rat organic anion transporter OATP-D
-
Adachi H, Suzuki T, Abe M, Asano N, Mizutamari H, Tanemoto M, Nishio T, Onogawa T, Toyohara T, Kasai S, Satoh F, Suzuki M, Tokui T, Unno M, Shimosegawa T, Matsuno S, Ito S, Abe T. 2003. Molecular characterization of human and rat organic anion transporter OATP-D. Am J Physiol Renal Physiol 285:F1188-F1197.
-
(2003)
Am J Physiol Renal Physiol
, vol.285
-
-
Adachi, H.1
Suzuki, T.2
Abe, M.3
Asano, N.4
Mizutamari, H.5
Tanemoto, M.6
Nishio, T.7
Onogawa, T.8
Toyohara, T.9
Kasai, S.10
Satoh, F.11
Suzuki, M.12
Tokui, T.13
Unno, M.14
Shimosegawa, T.15
Matsuno, S.16
Ito, S.17
Abe, T.18
-
46
-
-
14744274680
-
Regional intestinal absorption and biliary excretion of fluvastatin in the rat: Possible involvement of mrp2
-
Lindahl A, Sjoberg A, Bredberg U, Toreson H, Ungell AL, Lennernas H. 2004. Regional intestinal absorption and biliary excretion of fluvastatin in the rat: Possible involvement of mrp2. Mol Pharm 1:347-356.
-
(2004)
Mol Pharm
, vol.1
, pp. 347-356
-
-
Lindahl, A.1
Sjoberg, A.2
Bredberg, U.3
Toreson, H.4
Ungell, A.L.5
Lennernas, H.6
-
47
-
-
0042856460
-
Breast cancer resistance protein exports sulfated estrogens but not free estrogens
-
Imai Y, Asada S, Tsukahara S, Ishikawa E, Tsuruo T, Sugimoto Y. 2003. Breast cancer resistance protein exports sulfated estrogens but not free estrogens. Mol Pharmacol 64:610-618.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 610-618
-
-
Imai, Y.1
Asada, S.2
Tsukahara, S.3
Ishikawa, E.4
Tsuruo, T.5
Sugimoto, Y.6
-
48
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
Suzuki M, Suzuki H, Sugimoto Y, Sugiyama Y. 2003. ABCG2 transports sulfated conjugates of steroids and xenobiotics. J Biol Chem 278:22644-22649.
-
(2003)
J Biol Chem
, vol.278
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
49
-
-
6344242987
-
Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells
-
Prime-Chapman HM, Fearn RA, Cooper AE, Moore V, Hirst BH. 2004. Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. J Pharmacol Exp Ther 311:476-484.
-
(2004)
J Pharmacol Exp Ther
, vol.311
, pp. 476-484
-
-
Prime-Chapman, H.M.1
Fearn, R.A.2
Cooper, A.E.3
Moore, V.4
Hirst, B.H.5
-
50
-
-
0037081788
-
Influence of t-butylhydroquinone and beta-naphthoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers
-
Bock-Hennig BS, Kohle C, Nill K, Bock KW. 2002. Influence of t-butylhydroquinone and beta-naphthoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers. Biochem Pharmacol 63:123-128.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 123-128
-
-
Bock-Hennig, B.S.1
Kohle, C.2
Nill, K.3
Bock, K.W.4
-
51
-
-
0034723163
-
ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)
-
Hirohashi T, Suzuki H, Takikawa H, Sugiyama Y. 2000. ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3). J Biol Chem 275:2905-2910.
-
(2000)
J Biol Chem
, vol.275
, pp. 2905-2910
-
-
Hirohashi, T.1
Suzuki, H.2
Takikawa, H.3
Sugiyama, Y.4
-
52
-
-
0033591235
-
Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3)
-
Hirohashi T, Suzuki H, Sugiyama Y. 1999. Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3). J Biol Chem 274:15181-15185.
-
(1999)
J Biol Chem
, vol.274
, pp. 15181-15185
-
-
Hirohashi, T.1
Suzuki, H.2
Sugiyama, Y.3
-
53
-
-
0034282991
-
Transport of amphipathic anions by human multidrug resistance protein 3
-
Zeng H, Liu G, Rea PA, Kruh GD. 2000. Transport of amphipathic anions by human multidrug resistance protein 3. Cancer Res 60:4779-4784.
-
(2000)
Cancer Res
, vol.60
, pp. 4779-4784
-
-
Zeng, H.1
Liu, G.2
Rea, P.A.3
Kruh, G.D.4
-
54
-
-
0036149075
-
Transport activity of human MRP3 expressed in Sf9 cells: Comparative studies with rat MRP3
-
Akita H, Suzuki H, Hirohashi T, Takikawa H, Sugiyama Y. 2002. Transport activity of human MRP3 expressed in Sf9 cells: Comparative studies with rat MRP3. Pharm Res 19:34-41.
-
(2002)
Pharm Res
, vol.19
, pp. 34-41
-
-
Akita, H.1
Suzuki, H.2
Hirohashi, T.3
Takikawa, H.4
Sugiyama, Y.5
-
55
-
-
0037269403
-
Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter
-
Zelcer N, Saeki T, Bot I, Kuil A, Borst P. 2003. Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter. Biochem J 369:23-30.
-
(2003)
Biochem J
, vol.369
, pp. 23-30
-
-
Zelcer, N.1
Saeki, T.2
Bot, I.3
Kuil, A.4
Borst, P.5
-
56
-
-
85030583877
-
Simulating kinetic parameters in transporter mediated permeability across Caco-2 cells. A case study of estrone-3-sulfate (submitted)
-
Steffansen B, Rolsted K, Rapin N, Steffansen B. Simulating kinetic parameters in transporter mediated permeability across Caco-2 cells. A case study of estrone-3-sulfate (submitted). Eur J Pharm Sci.
-
Eur J Pharm Sci
-
-
Steffansen, B.1
Rolsted, K.2
Rapin, N.3
Steffansen, B.4
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