Impact of carriers in oral absorption: Permeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide

European Journal of Pharmaceutical Sciences

Volumn 37, Issue 3-4, 2009, Pages 378-386

  Gram, Luise K ^a,b   Rist, Gerda Marie ^b   Lennernäs, Hans ^c   Steffansen, Bente ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b LEO Pharma ^*  (Denmark)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Caco 2 cells; Carrier interactions; Estrone 3 sulfate; Glipizide; Organic anion carriers

Indexed keywords

BREAST CANCER RESISTANT PROTEIN; DRUG CARRIER; ESTRONE SULFATE; GLIPIZIDE; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC ANION TRANSPORTING POLYPEPTIDE 2B1; ORGANIC SOLUTE TRANSPORTER ALPHA; ORGANIC SOLUTE TRANSPORTER BETA; POLYPEPTIDE; PROTEIN; UNCLASSIFIED DRUG;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL STRAIN CACO 2; COLON ADENOCARCINOMA; DRUG ABSORPTION; DRUG PENETRATION; HUMAN; HUMAN CELL; KINETICS; PRIORITY JOURNAL;

ABSORPTION; ADMINISTRATION, ORAL; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; ESTROGENS, CONJUGATED (USP); ESTRONE; GLIPIZIDE; HUMANS; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS;

EID: 67349227126     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2009.03.008     Document Type: Article

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