Dietary n-3 fatty acids significantly suppress lipogenesis in bovine muscle and adipose tissue: A functional genomics approach

Lipids

Volumn 46, Issue 7, 2011, Pages 557-567

  Hiller, Beate ^a   Herdmann, Andrea ^a   Nuernberg, Karin ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

5D; 6D; ACC; FAS; Fatty acid profile; Functional genomic approach; Lipogenesis; SCD; SREBP1c

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; FATTY ACID SYNTHASE; LINOLEOYL COENZYME A DESATURASE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

ACETYL COENZYME A CARBOXYLASE GENE; ACYL COENZYME A DESATURASE GENE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COW; ENZYME ACTIVITY; FAT INTAKE; FATTY ACID ANALYSIS; FATTY ACID DESATURATION; FATTY ACID SYNTHASE GENE; FATTY ACID SYNTHESIS; FUNCTIONAL GENOMICS; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENOME ANALYSIS; LINOLEOYL COENZYME A DESATURASE GENE; LIPID COMPOSITION; LIPOGENESIS; LONGISSIMUS MUSCLE; METABOLIC REGULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; SKELETAL MUSCLE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C GENE; SUBCUTANEOUS FAT; THERAPY EFFECT; TISSUE SPECIFICITY;

ACETYL-COA CARBOXYLASE; ANIMAL FEED; ANIMALS; CATTLE; DIET; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; GENE EXPRESSION; LIPOGENESIS; MALE; MUSCLES; RNA, MESSENGER; STEAROYL-COA DESATURASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SUBCUTANEOUS FAT;

ANIMALIA; BOVINAE; ZEA MAYS;

EID: 79959894720     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-011-3571-z     Document Type: Article

References (53)

1. Givens DI, Kliem KE, Gibbs RA (2006) The role of meat as a source of n-3 polyunsaturated fatty acids in the human diet. Meat Sci 74:209-218 (Pubitemid 43975219)
2. Carpentier YA, Portois L, Malaisse WY (2006) n-3 Fatty acids and the metabolic syndrome. Am J Clin Nutr 83:1499S-1504S
3. van Dijk SJ, Feskens EJM, Bos MB, Hoelen DWM, Heijligenberg R, Bromhaar MG, de Groot LCPGM, de Vries JHM, Müller M, Afman LA (2009) A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome. Am J Clin Nutr 90:1656-1664
4. Gebauer SK, Psota TL, Harris WS, Kris-Etherton PM (2006) n-3 Fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits. Am J Clin Nutr 83:1526S-1535S
5. Howe P, Meyer B, Record S, Baghurst K (2006) Dietary intake of long-chain n-3 polyunsaturated fatty acids: contribution of meat sources. Nutr 22:47-53 (Pubitemid 43175784)
6. Woods VB, Fearon AM (2009) Dietary sources of unsaturated fatty acids for animals and their transfer into meat, milk and eggs: a review. Livestock Sci 126:1-20
7. Scollan N, Hocquette J-F, Nuernberg K, Dannenberger D, Richardson I, Moloney A (2006) Innovations in beef production systems that enhance the nutritional and health value of beef lipids and their relationship with meat quality. Meat Sci 74:17-33
8. Wood JD, Richardson RI, Nute GR, Fisher AV, Campo MM, Kasapidou E, Sheard PR, Enser M (2003) Effects of fatty acids on meat quality: a review. Meat Sci 66:21-32
9. Wood JD, Enser M, Fisher AV, Nute GR, Sheard PR, Richardson RI, Hughes SI, Whittington FM (2008) Fat deposition, fatty acid composition and meat quality: A review. Meat Sci 78:343-358 (Pubitemid 351172622)
10. Raes K, De Smet S, Demeyer D (2004) Effect of dietary fatty acids on incorporation of long chain polyunsaturated fatty acids and conjugated linoleic acid in lamb, beef and pork meat: a review. Anim Feed Sci Technol 113:199-221 (Pubitemid 38215164)
11. Nuernberg K, Fischer A, Nuernberg G, Ender K, Dannenberger D (2008) Meat quality and fatty acid composition of lipids in muscle and fatty tissue of Skudde lambs fed grass versus concentrate. Small Ruminant Res 74:279-283 (Pubitemid 350137719)
12. Lee MRF, Evans PR, Nute GR, Richardson RI, Scollan ND (2009) A comparison between red clover silage and grass silage feeding on fatty acid composition, meat stability and sensory quality of the M. longissimus muscle of dairy cull cows. Meat Sci 81:738-744
13. Machecha L, Dannenberger D, Nuernberg K, Nuernberg G, Hagemann E, Martin J (2010) Relationship between lipid peroxidation and antioxidant status in the muscle of German Holstein bulls fed n-3 and n-6 PUFA-enriched diets. J Agric Food Chem 58:8407-8413
14. Zhang S, Knight TJ, Reecy JM, Beitz DC (2008) DNA polymorphisms in bovine fatty acid synthase are associated with beef fatty acid composition. Anim Genet 39:62-70 (Pubitemid 351178362)
15. Zhang S, Knight TJ, Reecy JM, Wheeler TL, Shackelford SD, Cundiff LV, Beitz DC (2010) Associations of polymorphisms in the promoter I of bovine acetyl-CoA carboxylase-alpha gene with beef fatty acid composition. Anim Genet 41:417-420
16. Orrù L, Cifuni GF, Piasentier E, Corazzin M, Bovolenta S, Moioli B (2011) Association analyses of single nucleotide polymorphisms in the LEP and SCD1 genes on the fatty acid profile of muscle fat in Simmental bulls. Meat Sci 87:344-348
17. Bernard L, Leroux C, Chilliard Y (2008) Expression and nutritional regulation of lipogenic genes in the ruminant lactating mammary gland. Adv Exp Med Biol 606:67-108
18. Dervishi E, Serrano C, Joy M, Serrano M, Rodellar C, Calvo JH (2010) Effect of the feeding system on the fatty acid composition, expression of the Δ9-desaturase, peroxisome proliferator-activated receptor alpha, gamma, and sterol regulatory element binding protein 1 genes in the semitendinosus muscle of light lambs of the Rasa Aragonesa breed. BMC Vet Res 6:1-11
19. Herdmann A, Nuernberg K, Martin J, Nuernberg G, Doran O (2010) Effect of dietary fatty acids on expression of lipogenic enzymes and fatty acid profile in tissues of bulls. Anim 4:755-762
20. Ward RE, Woodward B, Otter N, Doran O (2010) Relationship between the expression of key lipogenic enzymes, fatty acid composition, and intramuscular fat content of Limousin and Aberdeen Angus cattle. Livestock Sci 127:22-29
21. Waters SM, Kelly JP, O'Boyle P, Moloney AP, Kenny DA (2009) Effect of level and duration of dietary n-3 polyunsaturated fatty acid supplementation on the transcriptional regulation of {Delta}9-desaturase in muscle of beef cattle. J Anim Sci 87:244-252
22. Vasta V, Priolo A, Scerra M, Hallett KG, Wood JD, Doran O (2009) Δ9 desaturase protein expression and fatty acid composition of longissimus muscle in lambs fed green herbage or concentrate with or without added tannins. Meat Sci 82:357-364
23. Herdmann A, Martin J, Nuernberg G, Dannenberger D, Nuernberg K (2010) Effect of dietary n-3 and n-6 PUFA on lipid composition of different tissues of German Holstein bulls and the fate of bioactive fatty acids during processing. J Agric Food Chem 58:8314-8321
24. Pfaffl MW, Horgan GW, Dempfle L (2002) Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:1-10
25. Folch J, Lees M, Stanley GHS (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509
26. Dannenberger D, Nuernberg G, Scollan N, Schabbel W, Steinhart H, Ender K, Nuernberg K (2004) Effect of diet on the deposition of n-3 fatty acids conjugated linoleic- and C18:1 trans fatty acid isomers in muscle lipids of German Holstein bulls. J Agric Food Chem 52:6607-6615
27. Enser M, Richardson RI, Wood JD, Gill BP, Sheard PR (2000) Feeding linseed to increase the n-3 PUFA of pork: fatty acid composition of muscle, adipose tissue, liver and sausages. Meat Sci 55:201-212
28. Kim S, Moustaid-Moussa N (2000) Secretory, endocrine and autocrine/paracrine function of the adipocyte. J Nutr 130:3110S-3115S
29. Taniguchi M, Mannen H, Oyama K, Shimakura Y, Oka A, Watanabe H, Kojima T, Komatsu M, Harper GS, Tsuji S (2004) Differences in stearoyl-CoA desaturase mRNA levels between Japanese Black and Holstein cattle. Livestock Prod Sci 87:215-220 (Pubitemid 38617293)
30. Dance LJE, Matthews KR, Doran O (2009) Effect of breed on fatty acid composition and stearoyl-CoA desaturase protein expression in the semimembranosus muscle and subcutaneous adipose tissue of cattle. Livestock Sci 125:291-297
31. Doran O, Moule SK, Teye GA, Whittington FM, Hallett KG, Wood JD (2006) A reduced protein diet induces stearoyl-CoA desaturase protein expression in pig muscle but not in subcutaneous adipose tissue: relationship with intramuscular lipid formation. Br J Nutr 95:609-617
32. Cánovas A, Estany J, Tor M, Pena RN, Doran O (2009) Acetyl-CoA carboxylase and stearoyl-CoA desaturase protein expression in subcutaneous adipose tissue is reduced in pigs selected for decreased backfat thickness at constant intramuscular fat content. J Anim Sci 87:3905-3914
33. Kokta TA, Dodsonb MV, Gertler A, Hill RA (2004) Intercellular signalling between adipose tissue and muscle tissue. Dom Anim Endocrinol 27:303-331 (Pubitemid 39415823)
34. Ohsaki H, Sawa T, Sasazaki S, Kano K, Taniguchi M, Mukai F, Mannen H (2007) Stearoyl-CoA desaturase mRNA expression during bovine adipocyte differentiation in primary culture derived from Japanese Black and Holstein cattle. Comp Biochem Physiol A 148:629-634 (Pubitemid 47484233)
35. Wang YH, Bower NI, Reverter A, Tan SH, De Jager N, Wang R, McWilliam SM, Café LM, Greenwood PL, Lehnert SA (2009) Gene expression patterns during intramuscular fat development in cattle. J Anim Sci 87:119-130
36. Chung KY, Lunt DK, Kawachi H, Yano H, Smith SB (2007) Lipogenesis and stearoyl-CoA desaturase gene expression and enzyme activity in adipose tissue of short- and long-fed Angus and Wagyu steers fed corn- or hay-based diets. J Anim Sci 85:380-387 (Pubitemid 46651899)
37. Guixuan Zhou G, Wang S, Wang Z, Zhu X, Shu G, Liao W, Yu K, Gao P, Xi Q, Wang X, Zhang Y, Yuan L, Jiang Q (2010) Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. Meat Sci 86:440-450
38. Bartoň L, Kott T, Bureš D, Řehák D, Zahrádková R, Kottová B (2010) The polymorphisms of stearoyl-CoA desaturase (SCD1) and sterol regulatory element binding protein-1 (SREBP-1) genes and their association with the fatty acid profile of muscle and subcutaneous fat in Fleckvieh bulls. Meat Sci 85:15-20
39. Smith SB, Kawachi H, Choi CB, Choi CW, Wu G, Sawyer JE (2009) Cellular regulation of bovine intramuscular adipose tissue development and composition. J Anim Sci 87:E72-E82
40. Pavan E, Duckett SK (2007) Corn oil supplementation to steers grazing endophyte-free tall fescue. II. Effects on longissimus muscle and subcutaneous adipose fatty acid composition and stearoyl-CoA desaturase activity and expression. J Anim Sci 85:1731-1740 (Pubitemid 47146736)
41. Dridi S, Taouis M, Gertler A, Decuypere E, Buyse J (2007) The regulation of stearoyl-CoA desaturase gene expression is tissue specific in chickens. J Endocrinol 192:229-236 (Pubitemid 46444413)
42. Matsuhashi T, Maruyama S, Uemoto Y, Kobayashi N, Mannen H, Abe T, Sakaguchi S, Kobayashi E (2011) Effects of bovine fatty acid synthase, stearoyl-coenzyme A desaturase, sterol regulatory element-binding protein 1, and growth hormone gene polymorphisms on fatty acid composition and carcass traits in Japanese Black cattle. J Anim Sci 89:12-22
43. Serra A, Mele M, La Comba F, Conte G, Buccioni A, Secchiari P (2009) Conjugated linoleic acid (CLA) content of meat from three muscles of Massese suckling lambs slaughtered at different weights. Meat Sci 81:396-404
44. Daniel ZC, Wynn RJ, Salter AM, Buttery PJ (2004) Differing effects of forage and concentrate diets on the oleic acid and conjugated linoleic acid content of sheep tissues: the role of stearoyl-CoA desaturase. J Anim Sci 82:747-758 (Pubitemid 38572338)
45. Deiuliis J, Shin J, Murphy E, Kronberg SL, Eastridge ML, Suh Y, Yoon JT, Lee K (2010) Bovine adipose triglyceride lipase is not altered and adipocyte fatty acid-binding protein is increased by dietary flaxseed. Lipids 45:963-973
46. Joseph SJ, Robbins KR, Pavan E, Pratt SL, Duckett SK, Rekaya R (2010) Effect of diet supplementation on the expression of bovine genes associated with fatty acid synthesis and metabolism. Bioinform Biol Insights 4:19-31
47. Lee S-H, Cho Y-M, Lee S-H, Kim B-S, Kim N-K, Choy Y-H, Kim K-H, Yoon D, Im S-K, Oh S-J, Park E-W (2008) Identification of marbling-related candidate genes in M. longissimus dorsi of high- and low marbled Hanwoo (Korean Native Cattle) steers. BMB reports 41:846-851
48. Dobrzyn A, Dobrzyn P (2006) Stearoyl-CoA desaturase - a new player in skeletal muscle metabolism regulation. J Physiol Pharmacol 57(S10):31-42 (Pubitemid 46548765)
49. Sampath H, Miyazaki M, Dobrzyn A, Ntambi JM (2007) Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem 282:2483-2493 (Pubitemid 47076774)
50. Geetha CJ, Herbein JH (2000) Healthier dairy fat using transvaccenic acid. Nutr Food Sci 30:304-309
51. Bonnet M, Faulconnier Y, Leroux C, Jurie C, Cassar-Malek I, Bauchart D, Boulesteix P, Pethick D, Hocquette JF, Chilliard Y (2007) Glucose-6-phosphate dehydrogenase and leptin are related to marbling differences among Limousin and Angus or Japanese Black x Angus steers. J Anim Sci 85:2882-2894 (Pubitemid 350105652)
52. Underwood KR, Tong J, Zhu MJ, Shen QW, Means WJ, Ford SP, Paisley SI, Hess BW, Du M (2007) Relationship between kinase phosphorylation, muscle fiber typing, and glycogen accumulation in longissimus muscle of beef cattle with high and low intramuscular fat. J Agric Food Chem 55:9698-9703 (Pubitemid 350205326)
53. Wells T (2009) Ghrelin - defender of fat. Prog Lipid Res 48:257-274