Computational investigation of the changing patterns of subtype specific NMDA receptor activation during physiological glutamatergic neurotransmission

PLoS Computational Biology

Volumn 7, Issue 6, 2011, Pages

  Singh, Pallab ^a   Hockenberry, Adam J ^a   Tiruvadi, Vineet R ^a   Meaney, David F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHYSIOLOGICAL MODELS; PHYSIOLOGY; SIGNALING;

COMPUTATIONAL INVESTIGATION; COMPUTATIONAL MODELLING; CONDITION; DENDRITIC SPINE; LONG-TERM POTENTIATIONS; NEURONAL SURVIVAL; NMDA RECEPTOR; RECEPTOR ACTIVATION; SELECTIVE ACTIVATION; SYNAPTIC PLASTICITY;

CHEMICAL ACTIVATION;

GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; CALCIUM;

ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DENDRITIC SPINE; GENE ACTIVATION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEUROTRANSMISSION; PHYSIOLOGICAL PROCESS; RECEPTOR SENSITIVITY; SIGNAL TRANSDUCTION; SYNAPTIC INHIBITION; ANALYSIS OF VARIANCE; BIOLOGICAL MODEL; BIOLOGY; HIPPOCAMPAL CA1 REGION; METABOLISM; METHODOLOGY; NONPARAMETRIC TEST; PHYSIOLOGY; STATISTICS; SYNAPSE; SYNAPTIC TRANSMISSION;

ANALYSIS OF VARIANCE; CA1 REGION, HIPPOCAMPAL; CALCIUM; COMPUTATIONAL BIOLOGY; DENDRITIC SPINES; GLUTAMIC ACID; MODELS, NEUROLOGICAL; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; STOCHASTIC PROCESSES; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 79959839748     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002106     Document Type: Article

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