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Volumn 115, Issue 6, 2010, Pages 1350-1362

NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamates induced neuronal cell death

Author keywords

glutamate; NR2A; NR2B; p38 mitogen activated protein kinase; STEP; tyrosine phosphatase

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN TYROSINE PHOSPHATASE; STRIATAL ENRICHED TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

EID: 78649994240     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07035.x     Document Type: Article
Times cited : (54)

References (60)
  • 1
    • 1842558602 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
    • Arundine M., and, Tymianski M., (2004) Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell. Mol. Life Sci. 61, 657-668.
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 657-668
    • Arundine, M.1    Tymianski, M.2
  • 2
    • 0035124607 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia
    • Barone F. C., Irving E. A., Ray A. M., et al. (2001a) Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. Med. Res. Rev. 21, 129-145.
    • (2001) Med. Res. Rev. , vol.21 , pp. 129-145
    • Barone, F.C.1    Irving, E.A.2    Ray, A.M.3
  • 3
    • 0035142857 scopus 로고    scopus 로고
    • SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia
    • Barone F. C., Irving E. A., Ray A. M., et al. (2001b) SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. J. Pharmacol. Exp. Ther. 296, 312-321.
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , pp. 312-321
    • Barone, F.C.1    Irving, E.A.2    Ray, A.M.3
  • 5
    • 3342948362 scopus 로고    scopus 로고
    • Moderate increases in intracellular calcium activate neuroprotective signals in hippocampal neurons
    • Bickler P. E., and, Fahlman C. S., (2004) Moderate increases in intracellular calcium activate neuroprotective signals in hippocampal neurons. Neuroscience 127, 673-683.
    • (2004) Neuroscience , vol.127 , pp. 673-683
    • Bickler, P.E.1    Fahlman, C.S.2
  • 6
    • 0033769568 scopus 로고    scopus 로고
    • Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses
    • Bolshakov V. Y., Carboni L., Cobb M. H., Siegelbaum S. A., and, Belardetti F., (2000) Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3-CA1 synapses. Nat. Neurosci. 3, 1107-1112.
    • (2000) Nat. Neurosci. , vol.3 , pp. 1107-1112
    • Bolshakov, V.Y.1    Carboni, L.2    Cobb, M.H.3    Siegelbaum, S.A.4    Belardetti, F.5
  • 8
    • 42549114708 scopus 로고    scopus 로고
    • Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia
    • Braithwaite S. P., Xu J., Leung J., Urfer R., Nikolich K., Oksenberg D., Lombroso P. J., and, Shamloo M., (2008) Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. Eur. J. Neurosci. 27, 2444-2452.
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 2444-2452
    • Braithwaite, S.P.1    Xu, J.2    Leung, J.3    Urfer, R.4    Nikolich, K.5    Oksenberg, D.6    Lombroso, P.J.7    Shamloo, M.8
  • 9
    • 0030932770 scopus 로고    scopus 로고
    • STEP: A family of brain-enriched PTPs. Alternative splicing produces transmembrane, cytosolic and truncated isoforms
    • Bult A., Zhao F., Dirkx Jr. R., Raghunathan A., Solimena M., and, Lombroso P. J., (1997) STEP: a family of brain-enriched PTPs. Alternative splicing produces transmembrane, cytosolic and truncated isoforms. Eur. J. Cell Biol. 72, 337-344.
    • (1997) Eur. J. Cell Biol. , vol.72 , pp. 337-344
    • Bult, A.1    Zhao, F.2    Dirkx, Jr.R.3    Raghunathan, A.4    Solimena, M.5    Lombroso, P.J.6
  • 10
    • 12144271690 scopus 로고    scopus 로고
    • The PSD95-nNOS interface: A target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death
    • Cao J., Viholainen J. I., Dart C., Warwick H. K., Leyland M. L., and, Courtney M. J., (2005) The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. J. Cell Biol. 168, 117-126.
    • (2005) J. Cell Biol. , vol.168 , pp. 117-126
    • Cao, J.1    Viholainen, J.I.2    Dart, C.3    Warwick, H.K.4    Leyland, M.L.5    Courtney, M.J.6
  • 11
    • 0030987928 scopus 로고    scopus 로고
    • Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons
    • Chen Q. X., Perkins K. L., Choi D. W., and, Wong R. K., (1997) Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons. J. Neurosci. 17, 4032-4036.
    • (1997) J. Neurosci. , vol.17 , pp. 4032-4036
    • Chen, Q.X.1    Perkins, K.L.2    Choi, D.W.3    Wong, R.K.4
  • 13
    • 0037470163 scopus 로고    scopus 로고
    • Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons
    • Cheng A., Wang S., Yang D., Xiao R., and, Mattson M. P., (2003) Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons. J. Biol. Chem. 278, 7591-7599.
    • (2003) J. Biol. Chem. , vol.278 , pp. 7591-7599
    • Cheng, A.1    Wang, S.2    Yang, D.3    Xiao, R.4    Mattson, M.P.5
  • 14
    • 0025265926 scopus 로고
    • The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
    • Choi D. W., and, Rothman S. M., (1990) The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13, 171-182.
    • (1990) Annu. Rev. Neurosci. , vol.13 , pp. 171-182
    • Choi, D.W.1    Rothman, S.M.2
  • 15
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U., Iadecola C., and, Moskowitz M. A., (1999) Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 22, 391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 16
    • 0141756280 scopus 로고    scopus 로고
    • Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro
    • Gisabella B., Rowan M. J., and, Anwyl R., (2003) Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro. Neuroscience 121, 297-305.
    • (2003) Neuroscience , vol.121 , pp. 297-305
    • Gisabella, B.1    Rowan, M.J.2    Anwyl, R.3
  • 17
    • 0033103342 scopus 로고    scopus 로고
    • Ischemic tolerance in murine cortical cell culture: Critical role for NMDA receptors
    • Grabb M. C., and, Choi D. W., (1999) Ischemic tolerance in murine cortical cell culture: critical role for NMDA receptors. J. Neurosci. 19, 1657-1662.
    • (1999) J. Neurosci. , vol.19 , pp. 1657-1662
    • Grabb, M.C.1    Choi, D.W.2
  • 18
    • 38749088708 scopus 로고    scopus 로고
    • NMDA-induced striatal brain damage and time-dependence reliability of thionin staining in rats
    • Haelewyn B., Alix P., Maubert E., and, Abraini J. H., (2008) NMDA-induced striatal brain damage and time-dependence reliability of thionin staining in rats. J. Neurosci. Methods 168, 479-482.
    • (2008) J. Neurosci. Methods , vol.168 , pp. 479-482
    • Haelewyn, B.1    Alix, P.2    Maubert, E.3    Abraini, J.H.4
  • 19
    • 0032524763 scopus 로고    scopus 로고
    • Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro
    • Horstmann S., Kahle P. J., and, Borasio G. D., (1998) Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro. J. Neurosci. Res. 52, 483-490.
    • (1998) J. Neurosci. Res. , vol.52 , pp. 483-490
    • Horstmann, S.1    Kahle, P.J.2    Borasio, G.D.3
  • 20
    • 0035970036 scopus 로고    scopus 로고
    • Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate- mediated neurotoxicity in cyclooxygenase-2-deficient mice
    • Iadecola C., Niwa K., Nogawa S., Zhao X., Nagayama M., Araki E., Morham S., and, Ross M. E., (2001) Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice. Proc. Natl Acad. Sci. USA 98, 1294-1299.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1294-1299
    • Iadecola, C.1    Niwa, K.2    Nogawa, S.3    Zhao, X.4    Nagayama, M.5    Araki, E.6    Morham, S.7    Ross, M.E.8
  • 21
  • 22
    • 0030741894 scopus 로고    scopus 로고
    • Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
    • Kawasaki H., Morooka T., Shimohama S., Kimura J., Hirano T., Gotoh Y., and, Nishida E., (1997) Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J. Biol. Chem. 272, 18518-18521.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18518-18521
    • Kawasaki, H.1    Morooka, T.2    Shimohama, S.3    Kimura, J.4    Hirano, T.5    Gotoh, Y.6    Nishida, E.7
  • 23
    • 19544367458 scopus 로고    scopus 로고
    • Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking
    • Kim M. J., Dunah A. W., Wang Y. T., and, Sheng M., (2005) Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking. Neuron 46, 745-760.
    • (2005) Neuron , vol.46 , pp. 745-760
    • Kim, M.J.1    Dunah, A.W.2    Wang, Y.T.3    Sheng, M.4
  • 24
    • 33748921093 scopus 로고    scopus 로고
    • NMDA receptor function: Subunit composition versus spatial distribution
    • Kohr G., (2006) NMDA receptor function: subunit composition versus spatial distribution. Cell Tissue Res. 326, 439-446.
    • (2006) Cell Tissue Res. , vol.326 , pp. 439-446
    • Kohr, G.1
  • 25
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • Kumar S., Boehm J., and, Lee J. C., (2003) p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat. Rev. Drug Discov. 2, 717-726.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 26
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton S. A., and, Rosenberg P. A., (1994) Excitatory amino acids as a final common pathway for neurologic disorders. N. Eng. J. Med. 330, 613-622.
    • (1994) N. Eng. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 27
    • 33947331063 scopus 로고    scopus 로고
    • NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
    • Liu Y., Wong T. P., Aarts M., et al. (2007) NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J. Neurosci. 27, 2846-2857.
    • (2007) J. Neurosci. , vol.27 , pp. 2846-2857
    • Liu, Y.1    Wong, T.P.2    Aarts, M.3
  • 28
    • 0031032658 scopus 로고    scopus 로고
    • The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B)
    • Luo J., Wang Y., Yasuda R. P., Dunah A. W., and, Wolfe B. B., (1997) The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B). Mol. Pharmacol. 51, 79-86.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 79-86
    • Luo, J.1    Wang, Y.2    Yasuda, R.P.3    Dunah, A.W.4    Wolfe, B.B.5
  • 29
    • 20444377686 scopus 로고    scopus 로고
    • Regulation of the cyclooxygenase-2 system by interleukin-1beta through mitogen-activated protein kinase signaling pathways: A comparative study of human neuroglioma and neuroblastoma cells
    • Moolwaney A. S., and, Igwe O. J., (2005) Regulation of the cyclooxygenase-2 system by interleukin-1beta through mitogen-activated protein kinase signaling pathways: a comparative study of human neuroglioma and neuroblastoma cells. Brain Res. Mol. Brain Res. 137, 202-212.
    • (2005) Brain Res. Mol. Brain Res. , vol.137 , pp. 202-212
    • Moolwaney, A.S.1    Igwe, O.J.2
  • 31
    • 0033525762 scopus 로고    scopus 로고
    • Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death
    • Mukherjee P. K., DeCoster M. A., Campbell F. Z., Davis R. J., and, Bazan N. G., (1999) Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death. J. Biol. Chem. 274, 6493-6498.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6493-6498
    • Mukherjee, P.K.1    Decoster, M.A.2    Campbell, F.Z.3    Davis, R.J.4    Bazan, N.G.5
  • 32
    • 0032578510 scopus 로고    scopus 로고
    • Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity
    • Murray B., Alessandrini A., Cole A. J., Yee A. G., and, Furshpan E. J., (1998) Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity. Proc. Natl Acad. Sci. USA 95, 11975-11980.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 11975-11980
    • Murray, B.1    Alessandrini, A.2    Cole, A.J.3    Yee, A.G.4    Furshpan, E.J.5
  • 33
    • 0037025303 scopus 로고    scopus 로고
    • Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420
    • Nguyen T. H., Liu J., and, Lombroso P. J., (2002) Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420. J. Biol. Chem. 277, 24274-24279.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24274-24279
    • Nguyen, T.H.1    Liu, J.2    Lombroso, P.J.3
  • 34
    • 52549132911 scopus 로고    scopus 로고
    • Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion
    • Nito C., Kamada H., Endo H., Niizuma K., Myer D. J., and, Chan P. H., (2008) Role of the p38 mitogen-activated protein kinase/cytosolic phospholipase A2 signaling pathway in blood-brain barrier disruption after focal cerebral ischemia and reperfusion. J. Cereb. Blood Flow Metab. 28, 1686-1696.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1686-1696
    • Nito, C.1    Kamada, H.2    Endo, H.3    Niizuma, K.4    Myer, D.J.5    Chan, P.H.6
  • 35
    • 0035997977 scopus 로고    scopus 로고
    • Role of p38 MAPK in the regulation of apoptosis signaling induced by TNF-alpha in differentiated PC12 cells
    • Park J. G., Yuk Y., Rhim H., Yi S. Y., and, Yoo Y. S., (2002) Role of p38 MAPK in the regulation of apoptosis signaling induced by TNF-alpha in differentiated PC12 cells. J. Biochem. Mol. Biol. 35, 267-272.
    • (2002) J. Biochem. Mol. Biol. , vol.35 , pp. 267-272
    • Park, J.G.1    Yuk, Y.2    Rhim, H.3    Yi, S.Y.4    Yoo, Y.S.5
  • 36
    • 77954705583 scopus 로고    scopus 로고
    • NR2B-NMDA receptor mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling
    • Paul S., and, Connor J,. (2010) NR2B-NMDA receptor mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling. J. Neurochem. 114, 1107-1118.
    • (2010) J. Neurochem. , vol.114 , pp. 1107-1118
    • Paul, S.1    Connor, J.2
  • 37
    • 0034255148 scopus 로고    scopus 로고
    • The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway
    • Paul S., Snyder G. L., Yokakura H., Picciotto M. R., Nairn A. C., and, Lombroso P. J., (2000) The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. J. Neurosci. 20, 5630-5638.
    • (2000) J. Neurosci. , vol.20 , pp. 5630-5638
    • Paul, S.1    Snyder, G.L.2    Yokakura, H.3    Picciotto, M.R.4    Nairn, A.C.5    Lombroso, P.J.6
  • 38
    • 0037220735 scopus 로고    scopus 로고
    • NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
    • Paul S., Nairn A. C., Wang P., and, Lombroso P. J., (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat. Neurosci. 6, 34-42.
    • (2003) Nat. Neurosci. , vol.6 , pp. 34-42
    • Paul, S.1    Nairn, A.C.2    Wang, P.3    Lombroso, P.J.4
  • 39
    • 33947310301 scopus 로고    scopus 로고
    • The striatal enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala
    • Paul S., Olausson P., Venkitaramani D. V., et al. (2007) The striatal enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala. Biol. Psychiatry 61, 1049-1061.
    • (2007) Biol. Psychiatry , vol.61 , pp. 1049-1061
    • Paul, S.1    Olausson, P.2    Venkitaramani, D.V.3
  • 41
    • 67650484107 scopus 로고    scopus 로고
    • Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death
    • Poddar R., and, Paul S., (2009) Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death. J. Neurochem. 110, 1095-1106.
    • (2009) J. Neurochem. , vol.110 , pp. 1095-1106
    • Poddar, R.1    Paul, S.2
  • 42
    • 0032534791 scopus 로고    scopus 로고
    • PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif
    • Pulido R., Zuniga A., and, Ullrich A., (1998) PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. EMBO J. 17, 7337-7350.
    • (1998) EMBO J. , vol.17 , pp. 7337-7350
    • Pulido, R.1    Zuniga, A.2    Ullrich, A.3
  • 43
    • 0037437356 scopus 로고    scopus 로고
    • Epsilon PKC is required for the induction of tolerance by ischemic and NMDA-mediated preconditioning in the organotypic hippocampal slice
    • Raval A. P., Dave K. R., Mochly-Rosen D., Sick T. J., and, Perez-Pinzon M. A., (2003) Epsilon PKC is required for the induction of tolerance by ischemic and NMDA-mediated preconditioning in the organotypic hippocampal slice. J. Neurosci. 23, 384-391.
    • (2003) J. Neurosci. , vol.23 , pp. 384-391
    • Raval, A.P.1    Dave, K.R.2    Mochly-Rosen, D.3    Sick, T.J.4    Perez-Pinzon, M.A.5
  • 44
    • 0346996446 scopus 로고    scopus 로고
    • Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium
    • Rockwell P., Martinez J., Papa L., and, Gomes E., (2004) Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium. Cell. Signal. 16, 343-353.
    • (2004) Cell. Signal. , vol.16 , pp. 343-353
    • Rockwell, P.1    Martinez, J.2    Papa, L.3    Gomes, E.4
  • 45
    • 0035449320 scopus 로고    scopus 로고
    • Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning
    • Rodrigues S. M., Schafe G. E., and, LeDoux J. E., (2001) Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning. J. Neurosci. 21, 6889-6896.
    • (2001) J. Neurosci. , vol.21 , pp. 6889-6896
    • Rodrigues, S.M.1    Schafe, G.E.2    Ledoux, J.E.3
  • 46
    • 0032530577 scopus 로고    scopus 로고
    • Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: Evidence for a MAP kinase-dependent mechanism
    • Runden E., Seglen P. O., Haug F. M., Ottersen O. P., Wieloch T., Shamloo M., and, Laake J. H., (1998) Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism. J. Neurosci. 18, 7296-7305.
    • (1998) J. Neurosci. , vol.18 , pp. 7296-7305
    • Runden, E.1    Seglen, P.O.2    Haug, F.M.3    Ottersen, O.P.4    Wieloch, T.5    Shamloo, M.6    Laake, J.H.7
  • 47
    • 0036876818 scopus 로고    scopus 로고
    • Calcium transients in the model of rapidly induced anoxic tolerance in rat cortical slices: Involvement of NMDA receptors
    • Semenov D. G., Samoilov M. O., and, Lazarewicz J. W., (2002) Calcium transients in the model of rapidly induced anoxic tolerance in rat cortical slices: involvement of NMDA receptors. Neuro-Signals 11, 329-335.
    • (2002) Neuro-Signals , vol.11 , pp. 329-335
    • Semenov, D.G.1    Samoilov, M.O.2    Lazarewicz, J.W.3
  • 48
    • 23044445669 scopus 로고    scopus 로고
    • Regulation of NMDA receptor trafficking by amyloid-beta
    • Snyder E. M., Nong Y., Almeida C. G., et al. (2005) Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci. 8, 1051-1058.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1051-1058
    • Snyder, E.M.1    Nong, Y.2    Almeida, C.G.3
  • 49
    • 0037040171 scopus 로고    scopus 로고
    • Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line
    • Stanciu M., and, DeFranco D. B., (2002) Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line. J. Biol. Chem. 277, 4010-4017.
    • (2002) J. Biol. Chem. , vol.277 , pp. 4010-4017
    • Stanciu, M.1    Defranco, D.B.2
  • 50
    • 3342919253 scopus 로고    scopus 로고
    • On the role of Ca2+ in cerebral ischemic preconditioning
    • Tauskela J. S., and, Morley P., (2004) On the role of Ca2+ in cerebral ischemic preconditioning. Cell Calcium 36, 313-322.
    • (2004) Cell Calcium , vol.36 , pp. 313-322
    • Tauskela, J.S.1    Morley, P.2
  • 51
    • 1342289413 scopus 로고    scopus 로고
    • MAPK cascade signalling and synaptic plasticity
    • Thomas G. M., and, Huganir R. L., (2004) MAPK cascade signalling and synaptic plasticity. Nat. Rev. Neurosci. 5, 173-183.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 173-183
    • Thomas, G.M.1    Huganir, R.L.2
  • 53
    • 0033562610 scopus 로고    scopus 로고
    • The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro
    • Tovar K. R., and, Westbrook G. L., (1999) The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J. Neurosci. 19, 4180-4188.
    • (1999) J. Neurosci. , vol.19 , pp. 4180-4188
    • Tovar, K.R.1    Westbrook, G.L.2
  • 54
    • 74549173438 scopus 로고    scopus 로고
    • DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke
    • Tu W., Xu X., Peng L., et al. (2010) DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke. Cell 140, 222-234.
    • (2010) Cell , vol.140 , pp. 222-234
    • Tu, W.1    Xu, X.2    Peng, L.3
  • 55
    • 39349108238 scopus 로고    scopus 로고
    • Amygdala infusions of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test
    • Walker D. L., and, Davis M., (2008) Amygdala infusions of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test. Learn. Mem. (Cold Spring Harbor, NY) 15, 67-74.
    • (2008) Learn. Mem. (Cold Spring Harbor, NY) , vol.15 , pp. 67-74
    • Walker, D.L.1    Davis, M.2
  • 56
    • 1842610852 scopus 로고    scopus 로고
    • Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
    • Wang Q., Walsh D. M., Rowan M. J., Selkoe D. J., and, Anwyl R., (2004) Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5. J. Neurosci. 24, 3370-3378.
    • (2004) J. Neurosci. , vol.24 , pp. 3370-3378
    • Wang, Q.1    Walsh, D.M.2    Rowan, M.J.3    Selkoe, D.J.4    Anwyl, R.5
  • 57
    • 23844533615 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase
    • Waxman E. A., and, Lynch D. R., (2005) N-methyl-D-aspartate receptor subtype mediated bidirectional control of p38 mitogen-activated protein kinase. J. Biol. Chem. 280, 29322-29333.
    • (2005) J. Biol. Chem. , vol.280 , pp. 29322-29333
    • Waxman, E.A.1    Lynch, D.R.2
  • 59
    • 24644506107 scopus 로고    scopus 로고
    • Roles of NMDA NR2B subtype receptor in pre long-term potentiation and contextual fear memory
    • Zhao M. G., Toyoda H., Lee Y. S., et al. (2005) Roles of NMDA NR2B subtype receptor in pre long-term potentiation and contextual fear memory. Neuron 47, 859-872.
    • (2005) Neuron , vol.47 , pp. 859-872
    • Zhao, M.G.1    Toyoda, H.2    Lee, Y.S.3
  • 60
    • 0037162696 scopus 로고    scopus 로고
    • Ras and Rap control AMPA receptor trafficking during synaptic plasticity
    • Zhu J. J., Qin Y., Zhao M., Van Aelst L., and, Malinow R., (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110, 443-455.
    • (2002) Cell , vol.110 , pp. 443-455
    • Zhu, J.J.1    Qin, Y.2    Zhao, M.3    Van Aelst, L.4    Malinow, R.5


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