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Volumn 90, Issue 1, 2011, Pages 49-60

Complementary and contrasting roles of NK cells and T cells in pediatric umbilical cord blood transplantation

Author keywords

Cytokines; MHC; Molecules; Primary cell

Indexed keywords

CD161 ANTIGEN; CD45 ANTIGEN; CD56 ANTIGEN; CD57 ANTIGEN; CD8 ANTIGEN; CYCLOSPORIN A; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 7; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; METHOTREXATE; METHYLPREDNISOLONE; NATURAL KILLER CELL RECEPTOR NKG2A; PERFORIN;

EID: 79959813984     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0111007     Document Type: Review
Times cited : (27)

References (154)
  • 3
    • 0042738931 scopus 로고    scopus 로고
    • Umbilical-cord blood transplantation for the treatment of cancer
    • Barker, J. N., Wagner, J. E. (2003) Umbilical-cord blood transplantation for the treatment of cancer. Nat. Rev. Cancer 3, 526-532.
    • (2003) Nat Rev. Cancer , vol.3 , pp. 526-532
    • Barker, J.N.1    Wagner, J.E.2
  • 4
    • 79959822841 scopus 로고    scopus 로고
    • National Marrow Donor Program
    • National Marrow Donor Program (2010) www.marrow.org/PHYSICIAN/URD_Search_and_Tx/Number_of_Allogeneic_Tx_Perfor/Index.html#grafts
    • (2010)
  • 5
    • 0029742950 scopus 로고    scopus 로고
    • Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: Analysis of engraftment and acute graftversus-host disease
    • Wagner, J. E., Rosenthal, J., Sweetman, R., Shu, X. O., Davies, S. M., Ramsay, N. K., McGlave, P. B., Sender, L., Cairo, M. S. (1996) Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graftversus-host disease. Blood 88, 795-802.
    • (1996) Blood , vol.88 , pp. 795-802
    • Wagner, J.E.1    Rosenthal, J.2    Sweetman, R.3    Shu, X.O.4    Davies, S.M.5    Ramsay, N.K.6    McGlave, P.B.7    Sender, L.8    Cairo, M.S.9
  • 7
    • 33947257506 scopus 로고    scopus 로고
    • A meta-analysis of unrelated donor umbilical cord blood transplantation versus unrelated donor bone marrow transplantation in adult and pediatric patients
    • Hwang, W. Y., Samuel, M., Tan, D., Koh, L. P., Lim, W., Linn, Y. C. (2007) A meta-analysis of unrelated donor umbilical cord blood transplantation versus unrelated donor bone marrow transplantation in adult and pediatric patients. Biol. Blood Marrow Transplant. 13, 444-453.
    • (2007) Biol. Blood Marrow Transplant , vol.13 , pp. 444-453
    • Hwang, W.Y.1    Samuel, M.2    Tan, D.3    Koh, L.P.4    Lim, W.5    Linn, Y.C.6
  • 9
    • 0027470021 scopus 로고
    • Stored placental blood for unrelated bone marrow reconstitution
    • Rubinstein, P., Rosenfield, R. E., Adamson, J. W., Stevens, C. E. (1993) Stored placental blood for unrelated bone marrow reconstitution. Blood 81, 1679-1690.
    • (1993) Blood , vol.81 , pp. 1679-1690
    • Rubinstein, P.1    Rosenfield, R.E.2    Adamson, J.W.3    Stevens, C.E.4
  • 10
    • 33746495044 scopus 로고    scopus 로고
    • Assessment of cord blood unit characteristics on the day of transplant: Comparison with data issued by cord blood banks
    • Wagner, E., Duval, M., Dalle, J. H., Morin, H., Bizier, S., Champagne, J., Champagne, M. A. (2006) Assessment of cord blood unit characteristics on the day of transplant: comparison with data issued by cord blood banks. Transfusion 46, 1190-1198.
    • (2006) Transfusion , vol.46 , pp. 1190-1198
    • Wagner, E.1    Duval, M.2    Dalle, J.H.3    Morin, H.4    Bizier, S.5    Champagne, J.6    Champagne, M.A.7
  • 11
    • 0034667539 scopus 로고    scopus 로고
    • Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation
    • Thomson, B. G., Robertson, K. A., Gowan, D., Heilman, D., Broxmeyer, H. E., Emanuel, D., Kotylo, P., Brahmi, Z., Smith, F. O. (2000) Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation. Blood 96, 2703-2711.
    • (2000) Blood , vol.96 , pp. 2703-2711
    • Thomson, B.G.1    Robertson, K.A.2    Gowan, D.3    Heilman, D.4    Broxmeyer, H.E.5    Emanuel, D.6    Kotylo, P.7    Brahmi, Z.8    Smith, F.O.9
  • 13
    • 29844452876 scopus 로고    scopus 로고
    • Clinical use of umbilical cord blood hematopoietic stem cells
    • Rocha, V., Gluckman, E. (2006) Clinical use of umbilical cord blood hematopoietic stem cells. Biol. Blood Marrow Transplant. 12, 34-41.
    • (2006) Biol. Blood Marrow Transplant , vol.12 , pp. 34-41
    • Rocha, V.1    Gluckman, E.2
  • 16
    • 58149165364 scopus 로고    scopus 로고
    • Results of the Cord Blood Transplantation Study (COBLT): Clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies
    • Kurtzberg, J., Prasad, V. K., Carter, S. L., Wagner, J. E., Baxter-Lowe, L. A., Wall, D., Kapoor, N., Guinan, E. C., Feig, S. A., Wagner, E. L., Kernan, N. A. (2008) Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. Blood 112, 4318-4327.
    • (2008) Blood , vol.112 , pp. 4318-4327
    • Kurtzberg, J.1    Prasad, V.K.2    Carter, S.L.3    Wagner, J.E.4    Baxter-Lowe, L.A.5    Wall, D.6    Kapoor, N.7    Guinan, E.C.8    Feig, S.A.9    Wagner, E.L.10    Kernan, N.A.11
  • 18
    • 68049105397 scopus 로고    scopus 로고
    • Lymphocyte recovery is a major determinant of outcome after matched unrelated myeloablative transplantation for myelogenous malignancies
    • Le Blanc, K., Barrett, A. J., Schaffer, M., Hagglund, H., Ljungman, P., Ringden, O., Remberger, M. (2009) Lymphocyte recovery is a major determinant of outcome after matched unrelated myeloablative transplantation for myelogenous malignancies. Biol. Blood Marrow Transplant. 15, 1108-1115.
    • (2009) Biol. Blood Marrow Transplant , vol.15 , pp. 1108-1115
    • le Blanc, K.1    Barrett, A.J.2    Schaffer, M.3    Hagglund, H.4    Ljungman, P.5    Ringden, O.6    Remberger, M.7
  • 19
    • 0141502196 scopus 로고    scopus 로고
    • Lymphocyte recovery after allogeneic bone marrow transplantation predicts risk of relapse in acute lymphoblastic leukemia
    • Kumar, S., Chen, M. G., Gastineau, D. A., Gertz, M. A., Inwards, D. J., Lacy, M. Q., Tefferi, A., Litzow, M. R. (2003) Lymphocyte recovery after allogeneic bone marrow transplantation predicts risk of relapse in acute lymphoblastic leukemia. Leukemia 17, 1865-1870.
    • (2003) Leukemia , vol.17 , pp. 1865-1870
    • Kumar, S.1    Chen, M.G.2    Gastineau, D.A.3    Gertz, M.A.4    Inwards, D.J.5    Lacy, M.Q.6    Tefferi, A.7    Litzow, M.R.8
  • 20
    • 39349110365 scopus 로고    scopus 로고
    • Early lymphocyte recovery post-allogeneic hematopoietic stem cell transplantation is associated with significant graft-versus-leukemia effect without increase in graft-versus-host disease in pediatric acute lymphoblastic leukemia
    • Ishaqi, M. K., Afzal, S., Dupuis, A., Doyle, J., Gassas, A. (2008) Early lymphocyte recovery post-allogeneic hematopoietic stem cell transplantation is associated with significant graft-versus-leukemia effect without increase in graft-versus-host disease in pediatric acute lymphoblastic leukemia. Bone Marrow Transplant. 41, 245-252.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 245-252
    • Ishaqi, M.K.1    Afzal, S.2    Dupuis, A.3    Doyle, J.4    Gassas, A.5
  • 21
    • 2042443767 scopus 로고    scopus 로고
    • Clinical impact of early absolute lymphocyte count after allogeneic stem cell transplantation
    • Kim, D. H., Kim, J. G., Sohn, S. K., Sung, W. J., Suh, J. S., Lee, K. S., Lee, K. B. (2004) Clinical impact of early absolute lymphocyte count after allogeneic stem cell transplantation. Br. J. Haematol. 125, 217-224.
    • (2004) Br. J. Haematol , vol.125 , pp. 217-224
    • Kim, D.H.1    Kim, J.G.2    Sohn, S.K.3    Sung, W.J.4    Suh, J.S.5    Lee, K.S.6    Lee, K.B.7
  • 26
    • 70349817631 scopus 로고    scopus 로고
    • Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: A tool for immunotherapy of leukemia
    • Velardi, A., Ruggeri, L., Mancusi, A., Aversa, F., Christiansen, F. T. (2009) Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: a tool for immunotherapy of leukemia. Curr. Opin. Immunol. 21, 525-530.
    • (2009) Curr. Opin. Immunol , vol.21 , pp. 525-530
    • Velardi, A.1    Ruggeri, L.2    Mancusi, A.3    Aversa, F.4    Christiansen, F.T.5
  • 27
    • 0037313360 scopus 로고    scopus 로고
    • Alloreactive killer cells: Hindrance and help for hematopoietic transplants
    • Parham, P., McQueen, K. L. (2003) Alloreactive killer cells: hindrance and help for hematopoietic transplants. Nat. Rev. Immunol. 3, 108-122.
    • (2003) Nat Rev. Immunol , vol.3 , pp. 108-122
    • Parham, P.1    McQueen, K.L.2
  • 33
    • 20844438187 scopus 로고    scopus 로고
    • NKcell reconstitution after haploidentical hematopoietic stem-cell transplantations: Immaturity of NK cells and inhibitory effect of NKG2A override GvL effect
    • Nguyen, S., Dhedin, N., Vernant, J. P., Kuentz, M., Al, J. A., Rouas-Freiss, N., Carosella, E. D., Boudifa, A., Debre, P., Vieillard, V. (2005) NKcell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect. Blood 105, 4135-4142.
    • (2005) Blood , vol.105 , pp. 4135-4142
    • Nguyen, S.1    Dhedin, N.2    Vernant, J.P.3    Kuentz, M.4    Al, J.A.5    Rouas-Freiss, N.6    Carosella, E.D.7    Boudifa, A.8    Debre, P.9    Vieillard, V.10
  • 35
    • 0034904255 scopus 로고    scopus 로고
    • NK cells recover early and mediate cytotoxicity via perforin/granzyme and Fas/FasL pathways in umbilical cord blood recipients
    • Brahmi, Z., Hommel-Berrey, G., Smith, F., Thomson, B. (2001) NK cells recover early and mediate cytotoxicity via perforin/granzyme and Fas/FasL pathways in umbilical cord blood recipients. Hum. Immunol. 62, 782-790.
    • (2001) Hum Immunol , vol.62 , pp. 782-790
    • Brahmi, Z.1    Hommel-Berrey, G.2    Smith, F.3    Thomson, B.4
  • 37
    • 77955502916 scopus 로고    scopus 로고
    • Umbilical cord blood T cells respond against the Melan-A/MART-1 tumor antigen and exhibit reduced alloreactivity as compared with adult blood-derived T cells
    • Merindol, N., Grenier, A. J., Caty, M., Charrier, E., Duval, A., Duval, M., Champagne, M. A., Soudeyns, H. (2010) Umbilical cord blood T cells respond against the Melan-A/MART-1 tumor antigen and exhibit reduced alloreactivity as compared with adult blood-derived T cells. J. Immunol. 185, 856-866.
    • (2010) J. Immunol , vol.185 , pp. 856-866
    • Merindol, N.1    Grenier, A.J.2    Caty, M.3    Charrier, E.4    Duval, A.5    Duval, M.6    Champagne, M.A.7    Soudeyns, H.8
  • 38
    • 0029943897 scopus 로고    scopus 로고
    • Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing
    • Mackall, C. L., Bare, C. V., Granger, L. A., Sharrow, S. O., Titus, J. A., Gress, R. E. (1996) Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J. Immunol. 156, 4609-4616.
    • (1996) J. Immunol , vol.156 , pp. 4609-4616
    • Mackall, C.L.1    Bare, C.V.2    Granger, L.A.3    Sharrow, S.O.4    Titus, J.A.5    Gress, R.E.6
  • 42
    • 10744220237 scopus 로고    scopus 로고
    • A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors
    • Eyrich, M., Leiler, C., Lang, P., Schilbach, K., Schumm, M., Bader, P., Greil, J., Klingebiel, T., Handgretinger, R., Niethammer, D., Schlegel, P. G. (2003) A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors. Bone Marrow Transplant. 32, 379-390.
    • (2003) Bone Marrow Transplant , vol.32 , pp. 379-390
    • Eyrich, M.1    Leiler, C.2    Lang, P.3    Schilbach, K.4    Schumm, M.5    Bader, P.6    Greil, J.7    Klingebiel, T.8    Handgretinger, R.9    Niethammer, D.10    Schlegel, P.G.11
  • 43
    • 0037082472 scopus 로고    scopus 로고
    • A broad T-cell repertoire diversity and an efficient thymic function indicate a favorable long-term immune reconstitution after cord blood stem cell transplantation
    • Talvensaari, K., Clave, E., Douay, C., Rabian, C., Garderet, L., Busson, M., Garnier, F., Douek, D., Gluckman, E., Charron, D., Toubert, A. (2002) A broad T-cell repertoire diversity and an efficient thymic function indicate a favorable long-term immune reconstitution after cord blood stem cell transplantation. Blood 99, 1458-1464.
    • (2002) Blood , vol.99 , pp. 1458-1464
    • Talvensaari, K.1    Clave, E.2    Douay, C.3    Rabian, C.4    Garderet, L.5    Busson, M.6    Garnier, F.7    Douek, D.8    Gluckman, E.9    Charron, D.10    Toubert, A.11
  • 44
    • 0033003612 scopus 로고    scopus 로고
    • Identification of human T-lymphoid progenitor cells in CD34+ CD38low and CD34+ CD38+ subsets of human cord blood and bone marrow cells using NOD-SCID fetal thymus organ cultures
    • Robin, C., Bennaceur-Griscelli, A., Louache, F., Vainchenker, W., Coulombel, L. (1999) Identification of human T-lymphoid progenitor cells in CD34+ CD38low and CD34+ CD38+ subsets of human cord blood and bone marrow cells using NOD-SCID fetal thymus organ cultures. Br. J. Haematol. 104, 809-819.
    • (1999) Br. J. Haematol , vol.104 , pp. 809-819
    • Robin, C.1    Bennaceur-Griscelli, A.2    Louache, F.3    Vainchenker, W.4    Coulombel, L.5
  • 45
    • 23944441502 scopus 로고    scopus 로고
    • T cell development and receptor diversity during aging
    • Goronzy, J. J., Weyand, C. M. (2005) T cell development and receptor diversity during aging. Curr. Opin. Immunol. 17, 468-475.
    • (2005) Curr. Opin. Immunol , vol.17 , pp. 468-475
    • Goronzy, J.J.1    Weyand, C.M.2
  • 47
    • 0034554787 scopus 로고    scopus 로고
    • Characterization of dendritic cell differentiation pathways from cord blood CD34+CD7+CD45RA+ hematopoietic progenitor cells
    • Canque, B., Camus, S., Dalloul, A., Kahn, E., Yagello, M., Dezutter-Dambuyant, C., Schmitt, D., Schmitt, C., Gluckman, J. C. (2000) Characterization of dendritic cell differentiation pathways from cord blood CD34+CD7+CD45RA+ hematopoietic progenitor cells. Blood 96, 3748-3756.
    • (2000) Blood , vol.96 , pp. 3748-3756
    • Canque, B.1    Camus, S.2    Dalloul, A.3    Kahn, E.4    Yagello, M.5    Dezutter-Dambuyant, C.6    Schmitt, D.7    Schmitt, C.8    Gluckman, J.C.9
  • 49
    • 0033485567 scopus 로고    scopus 로고
    • Human cord blood progenitors sustain thymic T-cell development and a novel form of angiogenesis
    • Crisa, L., Cirulli, V., Smith, K. A., Ellisman, M. H., Torbett, B. E., Salomon, D. R. (1999) Human cord blood progenitors sustain thymic T-cell development and a novel form of angiogenesis. Blood 94, 3928-3940.
    • (1999) Blood , vol.94 , pp. 3928-3940
    • Crisa, L.1    Cirulli, V.2    Smith, K.A.3    Ellisman, M.H.4    Torbett, B.E.5    Salomon, D.R.6
  • 52
    • 35548984981 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation after nonmyeloablative conditioning: Impact on transplantation outcomes in 110 adults with hematologic disease
    • Brunstein, C. G., Barker, J. N., Weisdorf, D. J., DeFor, T. E., Miller, J. S., Blazar, B. R., McGlave, P. B., Wagner, J. E. (2007) Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplantation outcomes in 110 adults with hematologic disease. Blood 110, 3064-3070.
    • (2007) Blood , vol.110 , pp. 3064-3070
    • Brunstein, C.G.1    Barker, J.N.2    Weisdorf, D.J.3    Defor, T.E.4    Miller, J.S.5    Blazar, B.R.6    McGlave, P.B.7    Wagner, J.E.8
  • 53
    • 12844273651 scopus 로고    scopus 로고
    • Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy
    • Barker, J. N., Weisdorf, D. J., DeFor, T. E., Blazar, B. R., McGlave, P. B., Miller, J. S., Verfaillie, C. M., Wagner, J. E. (2005) Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy. Blood 105, 1343-1347.
    • (2005) Blood , vol.105 , pp. 1343-1347
    • Barker, J.N.1    Weisdorf, D.J.2    Defor, T.E.3    Blazar, B.R.4    McGlave, P.B.5    Miller, J.S.6    Verfaillie, C.M.7    Wagner, J.E.8
  • 57
    • 0029068764 scopus 로고
    • Multiple minor histocompatibility antigen-specific cytotoxic T lymphocyte clones can be generated during graft rejection after HLA-identical bone marrow transplantation
    • Marijt, W. A., Kernan, N. A., Diaz-Barrientos, T., Veenhof, W. F., O'Reilly, R. J., Willemze, R., Falkenburg, J. H. (1995) Multiple minor histocompatibility antigen-specific cytotoxic T lymphocyte clones can be generated during graft rejection after HLA-identical bone marrow transplantation. Bone Marrow Transplant. 16, 125-132.
    • (1995) Bone Marrow Transplant , vol.16 , pp. 125-132
    • Marijt, W.A.1    Kernan, N.A.2    Diaz-Barrientos, T.3    Veenhof, W.F.4    O'Reilly, R.J.5    Willemze, R.6    Falkenburg, J.H.7
  • 58
    • 37348999625 scopus 로고    scopus 로고
    • Graft failure after allogeneic hematopoietic cell transplantation
    • Mattsson, J., Ringdén, O., Storb, R. (2008) Graft failure after allogeneic hematopoietic cell transplantation. Biol. Blood Marrow Transplant. 14 (Suppl.1), 165-170.
    • (2008) Biol. Blood Marrow Transplant , vol.14 , Issue.SUPPL. 1 , pp. 165-170
    • Mattsson, J.1    Ringdén, O.2    Storb, R.3
  • 59
    • 0026776346 scopus 로고
    • Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo
    • Murphy, W. J., Keller, J. R., Harrison, C. L., Young, H. A., Longo, D. L. (1992) Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo. Blood 80, 670-677.
    • (1992) Blood , vol.80 , pp. 670-677
    • Murphy, W.J.1    Keller, J.R.2    Harrison, C.L.3    Young, H.A.4    Longo, D.L.5
  • 60
    • 0031825656 scopus 로고    scopus 로고
    • IL-2-activated murine newborn liver NK cells enhance engraftment of hematopoietic stem cells in MHC-mismatched recipients
    • Hirayama, M., Genyea, C., Brownell, A., Kaplan, J. (1998) IL-2-activated murine newborn liver NK cells enhance engraftment of hematopoietic stem cells in MHC-mismatched recipients. Bone Marrow Transplant. 21, 1245-1252.
    • (1998) Bone Marrow Transplant , vol.21 , pp. 1245-1252
    • Hirayama, M.1    Genyea, C.2    Brownell, A.3    Kaplan, J.4
  • 61
    • 0027435048 scopus 로고
    • Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice
    • Siefer, A. K., Longo, D. L., Harrison, C. L., Reynolds, C. W., Murphy, W. J. (1993) Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice. Blood 82, 2577-2584.
    • (1993) Blood , vol.82 , pp. 2577-2584
    • Siefer, A.K.1    Longo, D.L.2    Harrison, C.L.3    Reynolds, C.W.4    Murphy, W.J.5
  • 62
    • 0031944075 scopus 로고    scopus 로고
    • NK cell receptors
    • Lanier, L. L. (1998) NK cell receptors. Annu. Rev. Immunol. 16, 359-393.
    • (1998) Annu. Rev. Immunol , vol.16 , pp. 359-393
    • Lanier, L.L.1
  • 65
    • 67049088404 scopus 로고    scopus 로고
    • Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity
    • Brunstein, C. G., Wagner, J. E., Weisdorf, D. J., Cooley, S., Noreen, H., Barker, J. N., DeFor, T., Verneris, M. R., Blazar, B. R., Miller, J. S. (2009) Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity. Blood 113, 5628-5634.
    • (2009) Blood , vol.113 , pp. 5628-5634
    • Brunstein, C.G.1    Wagner, J.E.2    Weisdorf, D.J.3    Cooley, S.4    Noreen, H.5    Barker, J.N.6    Defor, T.7    Verneris, M.R.8    Blazar, B.R.9    Miller, J.S.10
  • 66
    • 17744367418 scopus 로고    scopus 로고
    • Characterization of cord blood natural killer cells: Implications for transplantation and neonatal infections
    • Dalle, J. H., Menezes, J., Wagner, E., Blagdon, M., Champagne, J., Champagne, M. A., Duval, M. (2005) Characterization of cord blood natural killer cells: implications for transplantation and neonatal infections. Pediatr. Res. 57, 649-655.
    • (2005) Pediatr. Res , vol.57 , pp. 649-655
    • Dalle, J.H.1    Menezes, J.2    Wagner, E.3    Blagdon, M.4    Champagne, J.5    Champagne, M.A.6    Duval, M.7
  • 67
    • 65649111533 scopus 로고    scopus 로고
    • Binding of thymoglobulin to natural killer cells leads to cell activation and interferon-γ production
    • Dalle, J. H., Dardari, R., Menezes, J., Cordeiro, P., Champagne, M. A., Duval, M. (2009) Binding of thymoglobulin to natural killer cells leads to cell activation and interferon-γ production. Transplantation 87, 473-481.
    • (2009) Transplantation , vol.87 , pp. 473-481
    • Dalle, J.H.1    Dardari, R.2    Menezes, J.3    Cordeiro, P.4    Champagne, M.A.5    Duval, M.6
  • 68
    • 0030064563 scopus 로고    scopus 로고
    • Interleukin-12 induces interferon-γ expression and natural killer cytotoxicity in cord blood mononuclear cells
    • Lau, A. S., Sigaroudinia, M., Yeung, M. C., Kohl, S. (1996) Interleukin-12 induces interferon-γ expression and natural killer cytotoxicity in cord blood mononuclear cells. Pediatr. Res. 39, 150-155.
    • (1996) Pediatr. Res , vol.39 , pp. 150-155
    • Lau, A.S.1    Sigaroudinia, M.2    Yeung, M.C.3    Kohl, S.4
  • 69
  • 70
    • 0038798483 scopus 로고    scopus 로고
    • Analysis of natural killer (NK) cell activity and adhesion molecules on NK cells from umbilical cord blood
    • Tanaka, H., Kai, S., Yamaguchi, M., Misawa, M., Fujimori, Y., Yamamoto, M., Hara, H. (2003) Analysis of natural killer (NK) cell activity and adhesion molecules on NK cells from umbilical cord blood. Eur. J. Haematol. 71, 29-38.
    • (2003) Eur. J. Haematol , vol.71 , pp. 29-38
    • Tanaka, H.1    Kai, S.2    Yamaguchi, M.3    Misawa, M.4    Fujimori, Y.5    Yamamoto, M.6    Hara, H.7
  • 74
    • 6444245092 scopus 로고    scopus 로고
    • The contribution of cytotoxic and noncytotoxic function by donor T-cells that support engraftment after allogeneic bone marrow transplantation
    • Jiang, Z., Adams, G. B., Hanash, A. M., Scadden, D. T., Levy, R. B. (2002) The contribution of cytotoxic and noncytotoxic function by donor T-cells that support engraftment after allogeneic bone marrow transplantation. Biol. Blood Marrow Transplant. 8, 588-596.
    • (2002) Biol. Blood Marrow Transplant , vol.8 , pp. 588-596
    • Jiang, Z.1    Adams, G.B.2    Hanash, A.M.3    Scadden, D.T.4    Levy, R.B.5
  • 75
    • 34548670967 scopus 로고    scopus 로고
    • Umbilical cord blood xenografts in immunodeficient mice reveal that T cells enhance hematopoietic engraftment beyond overcoming immune barriers by stimulating stem cell differentiation
    • Hexner, E. O., Danet-Desnoyers, G. A., Zhang, Y., Frank, D. M., Riley, J. L., Levine, B. L., Porter, D. L., June, C. H., Emerson, S. G. (2007) Umbilical cord blood xenografts in immunodeficient mice reveal that T cells enhance hematopoietic engraftment beyond overcoming immune barriers by stimulating stem cell differentiation. Biol. Blood Marrow Transplant. 13, 1135-1144.
    • (2007) Biol. Blood Marrow Transplant , vol.13 , pp. 1135-1144
    • Hexner, E.O.1    Danet-Desnoyers, G.A.2    Zhang, Y.3    Frank, D.M.4    Riley, J.L.5    Levine, B.L.6    Porter, D.L.7    June, C.H.8    Emerson, S.G.9
  • 76
    • 0025258512 scopus 로고
    • The role of donor lymphoid cells in allogeneic marrow engraftment
    • Martin, P. J. (1990) The role of donor lymphoid cells in allogeneic marrow engraftment. Bone Marrow Transplant. 6, 283-289.
    • (1990) Bone Marrow Transplant , vol.6 , pp. 283-289
    • Martin, P.J.1
  • 77
    • 0029159761 scopus 로고
    • Augmentation of murine hematopoiesis by interleukin 2-activated irradiated T cells
    • Charak, B. S., Brown, E. G., Mazumder, A. (1995) Augmentation of murine hematopoiesis by interleukin 2-activated irradiated T cells. Transplantation 60, 589-594.
    • (1995) Transplantation , vol.60 , pp. 589-594
    • Charak, B.S.1    Brown, E.G.2    Mazumder, A.3
  • 78
    • 0038581912 scopus 로고    scopus 로고
    • The influence of HLA genotype on AIDS
    • Carrington, M., O'Brien, S. J. (2003) The influence of HLA genotype on AIDS. Annu. Rev. Med. 54, 535-551.
    • (2003) Annu Rev. Med , vol.54 , pp. 535-551
    • Carrington, M.1    O'Brien, S.J.2
  • 79
    • 73949144604 scopus 로고    scopus 로고
    • Reexposure of cord blood to noninherited maternal HLA antigens improves transplant outcome in hematological malignancies
    • Van Rood, J. J., Stevens, C. E., Smits, J., Carrier, C., Carpenter, C., Scaradavou, A. (2009) Reexposure of cord blood to noninherited maternal HLA antigens improves transplant outcome in hematological malignancies. Proc. Natl. Acad. Sci. USA 106, 19952-19957.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 19952-19957
    • van Rood, J.J.1    Stevens, C.E.2    Smits, J.3    Carrier, C.4    Carpenter, C.5    Scaradavou, A.6
  • 80
    • 77957062540 scopus 로고    scopus 로고
    • Allogeneic T cells impair engraftment and hematopoiesis after stem cell transplantation
    • Muller, A. M., Linderman, J. A., Florek, M., Miklos, D., Shizuru, J. A. (2010) Allogeneic T cells impair engraftment and hematopoiesis after stem cell transplantation. Proc. Natl. Acad. Sci. USA 107, 14721-14726.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 14721-14726
    • Muller, A.M.1    Linderman, J.A.2    Florek, M.3    Miklos, D.4    Shizuru, J.A.5
  • 82
    • 10744225349 scopus 로고    scopus 로고
    • Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults
    • Hamza, N. S., Lisgaris, M., Yadavalli, G., Nadeau, L., Fox, R., Fu, P., Lazarus, H. M., Koc, O. N., Salata, R. A., Laughlin, M. J. (2004) Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults. Br. J. Haematol. 124, 488-498.
    • (2004) Br. J. Haematol , vol.124 , pp. 488-498
    • Hamza, N.S.1    Lisgaris, M.2    Yadavalli, G.3    Nadeau, L.4    Fox, R.5    Fu, P.6    Lazarus, H.M.7    Koc, O.N.8    Salata, R.A.9    Laughlin, M.J.10
  • 89
    • 24744451399 scopus 로고    scopus 로고
    • Transplantation with higher dose of natural killer cells associated with better outcomes in terms of non-relapse mortality and infectious events after allogeneic peripheral blood stem cell transplantation from HLA-matched sibling donors
    • Kim, D. H., Sohn, S. K., Lee, N. Y., Baek, J. H., Kim, J. G., Won, D. I., Suh, J. S., Lee, K. B., Shin, I. H. (2005) Transplantation with higher dose of natural killer cells associated with better outcomes in terms of non-relapse mortality and infectious events after allogeneic peripheral blood stem cell transplantation from HLA-matched sibling donors. Eur. J. Haematol. 75, 299-308.
    • (2005) Eur. J. Haematol , vol.75 , pp. 299-308
    • Kim, D.H.1    Sohn, S.K.2    Lee, N.Y.3    Baek, J.H.4    Kim, J.G.5    Won, D.I.6    Suh, J.S.7    Lee, K.B.8    Shin, I.H.9
  • 91
    • 34948910572 scopus 로고    scopus 로고
    • Programmed death-1 (PD-1) defines a transient and dysfunctional oligoclonal T cell population in acute homeostatic proliferation
    • Lin, S. J., Peacock, C. D., Bahl, K., Welsh, R. M. (2007) Programmed death-1 (PD-1) defines a transient and dysfunctional oligoclonal T cell population in acute homeostatic proliferation. J. Exp. Med. 204, 2321-2333.
    • (2007) J. Exp. Med , vol.204 , pp. 2321-2333
    • Lin, S.J.1    Peacock, C.D.2    Bahl, K.3    Welsh, R.M.4
  • 93
    • 0033934283 scopus 로고    scopus 로고
    • Infection of human T lymphocytes with varicella-zoster virus: An analysis with viral mutants and clinical isolates
    • Soong, W., Schultz, J. C., Patera, A. C., Sommer, M. H., Cohen, J. I. (2000) Infection of human T lymphocytes with varicella-zoster virus: an analysis with viral mutants and clinical isolates. J. Virol. 74, 1864-1870.
    • (2000) J. Virol , vol.74 , pp. 1864-1870
    • Soong, W.1    Schultz, J.C.2    Patera, A.C.3    Sommer, M.H.4    Cohen, J.I.5
  • 94
    • 0033660932 scopus 로고    scopus 로고
    • Varicella-zoster virus: Pathogenesis, immunity, and clinical management in hematopoietic cell transplant recipients
    • Arvin, A. M. (2000) Varicella-zoster virus: pathogenesis, immunity, and clinical management in hematopoietic cell transplant recipients. Biol. Blood Marrow Transplant. 6, 219-230.
    • (2000) Biol. Blood Marrow Transplant , vol.6 , pp. 219-230
    • Arvin, A.M.1
  • 95
    • 26444541842 scopus 로고    scopus 로고
    • T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection
    • Schaap, A., Fortin, J. F., Sommer, M., Zerboni, L., Stamatis, S., Ku, C. C., Nolan, G. P., Arvin, A. M. (2005) T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection. J. Virol. 79, 12921-12933.
    • (2005) J. Virol , vol.79 , pp. 12921-12933
    • Schaap, A.1    Fortin, J.F.2    Sommer, M.3    Zerboni, L.4    Stamatis, S.5    Ku, C.C.6    Nolan, G.P.7    Arvin, A.M.8
  • 97
    • 5444245165 scopus 로고    scopus 로고
    • Varicella-zoster virus transfer to skin by T cells and modulation of viral replication by epidermal cell interferon-α
    • Ku, C. C., Zerboni, L., Ito, H., Graham, B. S., Wallace, M., Arvin, A. M. (2004) Varicella-zoster virus transfer to skin by T cells and modulation of viral replication by epidermal cell interferon-α. J. Exp. Med. 200, 917-925.
    • (2004) J. Exp. Med , vol.200 , pp. 917-925
    • Ku, C.C.1    Zerboni, L.2    Ito, H.3    Graham, B.S.4    Wallace, M.5    Arvin, A.M.6
  • 98
    • 0034968634 scopus 로고    scopus 로고
    • Varicella-zoster virus infection of human dendritic cells and transmission to T cells: Implications for virus dissemination in the host
    • Abendroth, A., Morrow, G., Cunningham, A. L., Slobedman, B. (2001) Varicella-zoster virus infection of human dendritic cells and transmission to T cells: implications for virus dissemination in the host. J. Virol. 75, 6183-6192.
    • (2001) J. Virol , vol.75 , pp. 6183-6192
    • Abendroth, A.1    Morrow, G.2    Cunningham, A.L.3    Slobedman, B.4
  • 101
    • 77950993215 scopus 로고    scopus 로고
    • Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation
    • Micklethwaite, K. P., Savoldo, B., Hanley, P. J., Leen, A. M., Demmler-Harrison, G. J., Cooper, L. J., Liu, H., Gee, A. P., Shpall, E. J., Rooney, C. M., Heslop, H. E., Brenner, M. K., Bollard, C. M., Dotti, G. (2010) Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation. Blood 115, 2695-2703.
    • (2010) Blood , vol.115 , pp. 2695-2703
    • Micklethwaite, K.P.1    Savoldo, B.2    Hanley, P.J.3    Leen, A.M.4    Demmler-Harrison, G.J.5    Cooper, L.J.6    Liu, H.7    Gee, A.P.8    Shpall, E.J.9    Rooney, C.M.10    Heslop, H.E.11    Brenner, M.K.12    Bollard, C.M.13    Dotti, G.14
  • 104
    • 74349115475 scopus 로고    scopus 로고
    • Clinical expansion of cord blood-derived T cells for use as donor lymphocyte infusion after cord blood transplantation
    • Okas, M., Gertow, J., Uzunel, M., Karlsson, H., Westgren, M., Karre, K., Ringden, O., Mattsson, J., Uhlin, M. (2010) Clinical expansion of cord blood-derived T cells for use as donor lymphocyte infusion after cord blood transplantation. J. Immunother. 33, 96-105.
    • (2010) J. Immunother , vol.33 , pp. 96-105
    • Okas, M.1    Gertow, J.2    Uzunel, M.3    Karlsson, H.4    Westgren, M.5    Karre, K.6    Ringden, O.7    Mattsson, J.8    Uhlin, M.9
  • 106
    • 0029780327 scopus 로고    scopus 로고
    • The immunopathophysiology of acute graft-versus-host-disease
    • Ferrara, J. L., Cooke, K. R., Pan, L., Krenger, W. (1996) The immunopathophysiology of acute graft-versus-host-disease. Stem Cells 14, 473-489.
    • (1996) Stem Cells , vol.14 , pp. 473-489
    • Ferrara, J.L.1    Cooke, K.R.2    Pan, L.3    Krenger, W.4
  • 107
    • 0029998991 scopus 로고    scopus 로고
    • Graft-versus-host disease and the Th1/Th2 paradigm
    • Krenger, W., Ferrara, J. L. (1996) Graft-versus-host disease and the Th1/Th2 paradigm. Immunol. Res. 15, 50-73.
    • (1996) Immunol Res , vol.15 , pp. 50-73
    • Krenger, W.1    Ferrara, J.L.2
  • 108
    • 0028289245 scopus 로고
    • The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: Comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma
    • Haczku, A., Alexander, A., Brown, P., Assoufi, B., Li, B., Kay, A. B., Corrigan, C. (1994) The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma. J. Allergy Clin. Immunol. 93, 510-519.
    • (1994) J. Allergy Clin. Immunol , vol.93 , pp. 510-519
    • Haczku, A.1    Alexander, A.2    Brown, P.3    Assoufi, B.4    Li, B.5    Kay, A.B.6    Corrigan, C.7
  • 109
    • 0022629855 scopus 로고
    • Influence of graft-versushost disease prophylaxis on early T-lymphocyte regeneration following allogeneic bone marrow transplantation
    • Gratama, J. W., Würsch, A. M., Nissen, C., Gratwohl, A., D'Amaro, J., de Gast, G. C., van Rood, J. J., Speck, B. (1986) Influence of graft-versushost disease prophylaxis on early T-lymphocyte regeneration following allogeneic bone marrow transplantation. Br. J. Haematol. 62, 355-365.
    • (1986) Br. J. Haematol , vol.62 , pp. 355-365
    • Gratama, J.W.1    Würsch, A.M.2    Nissen, C.3    Gratwohl, A.4    D'amaro, J.5    de Gast, G.C.6    van Rood, J.J.7    Speck, B.8
  • 110
    • 0034702284 scopus 로고    scopus 로고
    • Graft-versus-host disease in children who have received a cord-blood or bone marrow transplant from an HLA-identical sibling. Eurocord and International Bone Marrow Transplant Registry Working Committee on Alternative Donor and Stem Cell Sources
    • Rocha, V., Wagner Jr., J. E., Sobocinski, K. A., Klein, J. P., Zhang, M. J., Horowitz, M. M., Gluckman, E. (2000) Graft-versus-host disease in children who have received a cord-blood or bone marrow transplant from an HLA-identical sibling. Eurocord and International Bone Marrow Transplant Registry Working Committee on Alternative Donor and Stem Cell Sources. N. Engl. J. Med. 342, 1846-1854.
    • (2000) N. Engl. J. Med , vol.342 , pp. 1846-1854
    • Rocha, V.1    Wagner, J.E.2    Sobocinski, K.A.3    Klein, J.P.4    Zhang, M.J.5    Horowitz, M.M.6    Gluckman, E.7
  • 111
    • 64049100784 scopus 로고    scopus 로고
    • Acute graftversus-host disease after unrelated donor umbilical cord blood transplantation: Analysis of risk factors
    • MacMillan, M. L., Weisdorf, D. J., Brunstein, C. G., Cao, Q., DeFor, T. E., Verneris, M. R., Blazar, B. R., Wagner, J. E. (2009) Acute graftversus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors. Blood 113, 2410-2415.
    • (2009) Blood , vol.113 , pp. 2410-2415
    • Macmillan, M.L.1    Weisdorf, D.J.2    Brunstein, C.G.3    Cao, Q.4    Defor, T.E.5    Verneris, M.R.6    Blazar, B.R.7    Wagner, J.E.8
  • 112
    • 0028928464 scopus 로고
    • Cord blood T lymphocytes lack constitutive perforin expression in contrast to adult peripheral blood T lymphocytes
    • Berthou, C., Legros-Maida, S., Soulie, A., Wargnier, A., Guillet, J., Rabian, C., Gluckman, E., Sasportes, M. (1995) Cord blood T lymphocytes lack constitutive perforin expression in contrast to adult peripheral blood T lymphocytes. Blood 85, 1540-1546.
    • (1995) Blood , vol.85 , pp. 1540-1546
    • Berthou, C.1    Legros-Maida, S.2    Soulie, A.3    Wargnier, A.4    Guillet, J.5    Rabian, C.6    Gluckman, E.7    Sasportes, M.8
  • 113
    • 0346786460 scopus 로고    scopus 로고
    • Distinctive response of nai{dotless}̈ve lymphocytes from cord blood to primary activation via TCR
    • Cantó, E., Rodriguez-Sanchez, J. L., Vidal, S. (2003) Distinctive response of nai{dotless}̈ve lymphocytes from cord blood to primary activation via TCR. J. Leukoc. Biol. 74, 998-1007.
    • (2003) J. Leukoc. Biol , vol.74 , pp. 998-1007
    • Cantó, E.1    Rodriguez-Sanchez, J.L.2    Vidal, S.3
  • 115
    • 11244268818 scopus 로고    scopus 로고
    • Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
    • Godfrey, W. R., Spoden, D. J., Ge, Y. G., Baker, S. R., Liu, B., Levine, B. L., June, C. H., Blazar, B. R., Porter, S. B. (2005) Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood 105, 750-758.
    • (2005) Blood , vol.105 , pp. 750-758
    • Godfrey, W.R.1    Spoden, D.J.2    Ge, Y.G.3    Baker, S.R.4    Liu, B.5    Levine, B.L.6    June, C.H.7    Blazar, B.R.8    Porter, S.B.9
  • 116
    • 14744287197 scopus 로고    scopus 로고
    • Development and activation of regulatory T cells in the human fetus
    • Cupedo, T., Nagasawa, M., Weijer, K., Blom, B., Spits, H. (2005) Development and activation of regulatory T cells in the human fetus. Eur. J. Immunol. 35, 383-390.
    • (2005) Eur. J. Immunol , vol.35 , pp. 383-390
    • Cupedo, T.1    Nagasawa, M.2    Weijer, K.3    Blom, B.4    Spits, H.5
  • 118
    • 0032080398 scopus 로고    scopus 로고
    • Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation
    • Asai, O., Longo, D. L., Tian, Z. G., Hornung, R. L., Taub, D. D., Ruscetti, F. W., Murphy, W. J. (1998) Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation. J. Clin. Invest. 101, 1835-1842.
    • (1998) J. Clin. Invest , vol.101 , pp. 1835-1842
    • Asai, O.1    Longo, D.L.2    Tian, Z.G.3    Hornung, R.L.4    Taub, D.D.5    Ruscetti, F.W.6    Murphy, W.J.7
  • 119
    • 77953644448 scopus 로고    scopus 로고
    • NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects
    • Olson, J. A., Leveson-Gower, D. B., Gill, S., Baker, J., Beilhack, A., Negrin, R. S. (2010) NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects. Blood 115, 4293-4301.
    • (2010) Blood , vol.115 , pp. 4293-4301
    • Olson, J.A.1    Leveson-Gower, D.B.2    Gill, S.3    Baker, J.4    Beilhack, A.5    Negrin, R.S.6
  • 123
    • 0030754892 scopus 로고    scopus 로고
    • Human minor histocompatibility antigens: New concepts for marrow transplantation and adoptive immunotherapy
    • Goulmy, E. (1997) Human minor histocompatibility antigens: new concepts for marrow transplantation and adoptive immunotherapy. Immunol. Rev. 157, 125-140.
    • (1997) Immunol Rev , vol.157 , pp. 125-140
    • Goulmy, E.1
  • 124
    • 0036838306 scopus 로고    scopus 로고
    • Minor histocompatibility antigens as targets of graft-versus-leukemia reactions
    • Falkenburg, J. H., Marijt, W. A., Heemskerk, M. H., Willemze, R. (2002) Minor histocompatibility antigens as targets of graft-versus-leukemia reactions. Curr. Opin. Hematol. 9, 497-502.
    • (2002) Curr. Opin. Hematol , vol.9 , pp. 497-502
    • Falkenburg, J.H.1    Marijt, W.A.2    Heemskerk, M.H.3    Willemze, R.4
  • 125
    • 0030737629 scopus 로고    scopus 로고
    • High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome
    • Bergmann, L., Miething, C., Maurer, U., Brieger, J., Karakas, T., Weidmann, E., Hoelzer, D. (1997) High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome. Blood 90, 1217-1225.
    • (1997) Blood , vol.90 , pp. 1217-1225
    • Bergmann, L.1    Miething, C.2    Maurer, U.3    Brieger, J.4    Karakas, T.5    Weidmann, E.6    Hoelzer, D.7
  • 126
    • 0029069227 scopus 로고
    • Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias
    • Menssen, H. D., Renkl, H. J., Rodeck, U., Maurer, J., Notter, M., Schwartz, S., Reinhardt, R., Thiel, E. (1995) Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias. Leukemia 9, 1060-1067.
    • (1995) Leukemia , vol.9 , pp. 1060-1067
    • Menssen, H.D.1    Renkl, H.J.2    Rodeck, U.3    Maurer, J.4    Notter, M.5    Schwartz, S.6    Reinhardt, R.7    Thiel, E.8
  • 127
    • 0028130136 scopus 로고
    • WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia
    • Inoue, K., Sugiyama, H., Ogawa, H., Nakagawa, M., Yamagami, T., Miwa, H., Kita, K., Hiraoka, A., Masaoka, T., Nasu, K. (1994) WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 84, 3071-3079.
    • (1994) Blood , vol.84 , pp. 3071-3079
    • Inoue, K.1    Sugiyama, H.2    Ogawa, H.3    Nakagawa, M.4    Yamagami, T.5    Miwa, H.6    Kita, K.7    Hiraoka, A.8    Masaoka, T.9    Nasu, K.10
  • 130
    • 0037623948 scopus 로고    scopus 로고
    • Rapid establishment of long-term culture-initiating cells of donor origin after nonmyeloablative allogeneic hematopoietic stem-cell transplantation, and significant prognostic impact of donor T-cell chimerism on stable engraftment and progression-free survival
    • Keil, F., Prinz, E., Moser, K., Mannhalter, C., Kalhs, P., Worel, N., Rabitsch, W., Schulenburg, A., Mitterbauer, M., Greinix, H. (2003) Rapid establishment of long-term culture-initiating cells of donor origin after nonmyeloablative allogeneic hematopoietic stem-cell transplantation, and significant prognostic impact of donor T-cell chimerism on stable engraftment and progression-free survival. Transplantation 76, 230-236.
    • (2003) Transplantation , vol.76 , pp. 230-236
    • Keil, F.1    Prinz, E.2    Moser, K.3    Mannhalter, C.4    Kalhs, P.5    Worel, N.6    Rabitsch, W.7    Schulenburg, A.8    Mitterbauer, M.9    Greinix, H.10
  • 131
    • 33847306904 scopus 로고    scopus 로고
    • Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia
    • Huisman, C., de Weger, R. A., de Vries, L., Tilanus, M. G., Verdonck, L. F. (2007) Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia. Bone Marrow Transplant. 39, 285-291.
    • (2007) Bone Marrow Transplant , vol.39 , pp. 285-291
    • Huisman, C.1    de Weger, R.A.2    de Vries, L.3    Tilanus, M.G.4    Verdonck, L.F.5
  • 133
    • 0033750512 scopus 로고    scopus 로고
    • Antitumor therapeutic potential of activated human umbilical cord blood cells against leukemia and breast cancer
    • Joshi, S. S., Tarantolo, S. R., Kuszynski, C. A., Kessinger, A. (2000) Antitumor therapeutic potential of activated human umbilical cord blood cells against leukemia and breast cancer. Clin. Cancer Res. 6, 4351-4358.
    • (2000) Clin Cancer Res , vol.6 , pp. 4351-4358
    • Joshi, S.S.1    Tarantolo, S.R.2    Kuszynski, C.A.3    Kessinger, A.4
  • 134
    • 77956527811 scopus 로고    scopus 로고
    • Ultrastructural basis of enhanced antitumor cytotoxicity of cord blood-derived CTLs: A comparative analysis with peripheral blood and bone marrow
    • Clark, E. M., Joshi, D. S., Grimm, A. B., Joshi, A. D., Wang, P., Joshi, S. S. (2010) Ultrastructural basis of enhanced antitumor cytotoxicity of cord blood-derived CTLs: a comparative analysis with peripheral blood and bone marrow. Int. J. Oncol. 37, 645-653.
    • (2010) Int. J. Oncol , vol.37 , pp. 645-653
    • Clark, E.M.1    Joshi, D.S.2    Grimm, A.B.3    Joshi, A.D.4    Wang, P.5    Joshi, S.S.6
  • 135
    • 51649085790 scopus 로고    scopus 로고
    • Ex vivo expansion and Th1/Tc1 maturation of umbilical cord blood T cells by CD3/CD28 costimulation
    • Mazur, M. A., Davis, C. C., Szabolcs, P. (2008) Ex vivo expansion and Th1/Tc1 maturation of umbilical cord blood T cells by CD3/CD28 costimulation. Biol. Blood Marrow Transplant. 14, 1190-1196.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 1190-1196
    • Mazur, M.A.1    Davis, C.C.2    Szabolcs, P.3
  • 136
    • 77954370530 scopus 로고    scopus 로고
    • Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: A critical step toward adoptive immunotherapy after cord blood transplantation
    • Davis, C. C., Marti, L. C., Sempowski, G. D., Jeyaraj, D. A., Szabolcs, P. (2010) Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation. Cancer Res. 70, 5249-5258.
    • (2010) Cancer Res , vol.70 , pp. 5249-5258
    • Davis, C.C.1    Marti, L.C.2    Sempowski, G.D.3    Jeyaraj, D.A.4    Szabolcs, P.5
  • 139
    • 13844314521 scopus 로고    scopus 로고
    • Mechanisms of resistance to natural killer cell-mediated cytotoxicity in acute lymphoblastic leukemia
    • Romanski, A., Bug, G., Becker, S., Kampfmann, M., Seifried, E., Hoelzer, D., Ottmann, O. G., Tonn, T. (2005) Mechanisms of resistance to natural killer cell-mediated cytotoxicity in acute lymphoblastic leukemia. Exp. Hematol. 33, 344-352.
    • (2005) Exp Hematol , vol.33 , pp. 344-352
    • Romanski, A.1    Bug, G.2    Becker, S.3    Kampfmann, M.4    Seifried, E.5    Hoelzer, D.6    Ottmann, O.G.7    Tonn, T.8
  • 140
    • 34548779134 scopus 로고    scopus 로고
    • Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells
    • Kato, N., Tanaka, J., Sugita, J., Toubai, T., Miura, Y., Ibata, M., Syono, Y., Ota, S., Kondo, T., Asaka, M., Imamura, M. (2007) Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells. Leukemia 21, 2103-2108.
    • (2007) Leukemia , vol.21 , pp. 2103-2108
    • Kato, N.1    Tanaka, J.2    Sugita, J.3    Toubai, T.4    Miura, Y.5    Ibata, M.6    Syono, Y.7    Ota, S.8    Kondo, T.9    Asaka, M.10    Imamura, M.11
  • 141
    • 22044456688 scopus 로고    scopus 로고
    • Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
    • Imai, C., Iwamoto, S., Campana, D. (2005) Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells. Blood 106, 376-383.
    • (2005) Blood , vol.106 , pp. 376-383
    • Imai, C.1    Iwamoto, S.2    Campana, D.3
  • 143
    • 15244346488 scopus 로고    scopus 로고
    • Genotypic inhibitory killer immunoglobulin-like receptor ligand incompatibility enhances the longterm antileukemic effect of unmodified allogeneic hematopoietic stem cell transplantation in patients with myeloid leukemias
    • Beelen, D. W., Ottinger, H. D., Ferencik, S., Elmaagacli, A. H., Peceny, R., Trenschel, R., Grosse-Wilde, H. (2005) Genotypic inhibitory killer immunoglobulin-like receptor ligand incompatibility enhances the longterm antileukemic effect of unmodified allogeneic hematopoietic stem cell transplantation in patients with myeloid leukemias. Blood 105, 2594-2600.
    • (2005) Blood , vol.105 , pp. 2594-2600
    • Beelen, D.W.1    Ottinger, H.D.2    Ferencik, S.3    Elmaagacli, A.H.4    Peceny, R.5    Trenschel, R.6    Grosse-Wilde, H.7
  • 144
    • 63849104548 scopus 로고    scopus 로고
    • Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: Evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity
    • Pende, D., Marcenaro, S., Falco, M., Martini, S., Bernardo, M. E., Montagna, D., Romeo, E., Cognet, C., Martinetti, M., Maccario, R., Mingari, M. C., Vivier, E., Moretta, L., Locatelli, F., Moretta, A. (2009) Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity. Blood 113, 3119-3129.
    • (2009) Blood , vol.113 , pp. 3119-3129
    • Pende, D.1    Marcenaro, S.2    Falco, M.3    Martini, S.4    Bernardo, M.E.5    Montagna, D.6    Romeo, E.7    Cognet, C.8    Martinetti, M.9    Maccario, R.10    Mingari, M.C.11    Vivier, E.12    Moretta, L.13    Locatelli, F.14    Moretta, A.15
  • 145
    • 0842285644 scopus 로고    scopus 로고
    • The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia
    • Cook, M. A., Milligan, D. W., Fegan, C. D., Darbyshire, P. J., Mahendra, P., Craddock, C. F., Moss, P. A., Briggs, D. C. (2004) The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia. Blood 103, 1521-1526.
    • (2004) Blood , vol.103 , pp. 1521-1526
    • Cook, M.A.1    Milligan, D.W.2    Fegan, C.D.3    Darbyshire, P.J.4    Mahendra, P.5    Craddock, C.F.6    Moss, P.A.7    Briggs, D.C.8
  • 146
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes
    • Hsu, K. C., Keever-Taylor, C. A., Wilton, A., Pinto, C., Heller, G., Arkun, K., O'Reilly, R. J., Horowitz, M. M., Dupont, B. (2005) Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes. Blood 105, 4878-4884.
    • (2005) Blood , vol.105 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3    Pinto, C.4    Heller, G.5    Arkun, K.6    O'Reilly, R.J.7    Horowitz, M.M.8    Dupont, B.9
  • 147
    • 23744449591 scopus 로고    scopus 로고
    • A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation
    • Verheyden, S., Schots, R., Duquet, W., Demanet, C. (2005) A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation. Leukemia 19, 1446-1451.
    • (2005) Leukemia , vol.19 , pp. 1446-1451
    • Verheyden, S.1    Schots, R.2    Duquet, W.3    Demanet, C.4
  • 148
    • 70249096604 scopus 로고    scopus 로고
    • Characterization of natural killer and natural killerlike T cells derived from ex vivo expanded and activated cord blood mononuclear cells: Implications for adoptive cellular immunotherapy
    • Ayello, J., van de Ven, C., Cairo, E., Hochberg, J., Baxi, L., Satwani, P., Cairo, M. S. (2009) Characterization of natural killer and natural killerlike T cells derived from ex vivo expanded and activated cord blood mononuclear cells: implications for adoptive cellular immunotherapy. Exp. Hematol. 37, 1216-1229.
    • (2009) Exp Hematol , vol.37 , pp. 1216-1229
    • Ayello, J.1    van de Ven, C.2    Cairo, E.3    Hochberg, J.4    Baxi, L.5    Satwani, P.6    Cairo, M.S.7
  • 149
    • 70349817631 scopus 로고    scopus 로고
    • Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: A tool for immunotherapy of leukemia
    • Velardi, A., Ruggeri, L., Mancusi, A., Aversa, F., Christiansen, F. T. (2009) Natural killer cell allorecognition of missing self in allogeneic hematopoietic transplantation: a tool for immunotherapy of leukemia. Curr. Opin. Immunol. 21, 525-530.
    • (2009) Curr. Opin. Immunol , vol.21 , pp. 525-530
    • Velardi, A.1    Ruggeri, L.2    Mancusi, A.3    Aversa, F.4    Christiansen, F.T.5
  • 151
    • 77949312836 scopus 로고    scopus 로고
    • Single-unit dominance after doubleunit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit
    • Gutman, J. A., Turtle, C. J., Manley, T. J., Heimfeld, S., Bernstein, I. D., Riddell, S. R., Delaney, C. (2010) Single-unit dominance after doubleunit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit. Blood 115, 757-765.
    • (2010) Blood , vol.115 , pp. 757-765
    • Gutman, J.A.1    Turtle, C.J.2    Manley, T.J.3    Heimfeld, S.4    Bernstein, I.D.5    Riddell, S.R.6    Delaney, C.7
  • 152
    • 21344451855 scopus 로고    scopus 로고
    • T cell-mediated immune responses in human newborns: Ready to learn?
    • Marchant, A., Goldman, M. (2005) T cell-mediated immune responses in human newborns: ready to learn? Clin. Exp. Immunol. 141, 10-18.
    • (2005) Clin Exp Immunol , vol.141 , pp. 10-18
    • Marchant, A.1    Goldman, M.2
  • 153
    • 49149109119 scopus 로고    scopus 로고
    • Fine specificity of neonatal lymphocytes to an abundant malaria blood-stage antigen: Epitope mapping of Plasmodium falciparum MSP1(33)
    • Malhotra, I., Wamachi, A. N., Mungai, P. L., Mzungu, E., Koech, D., Muchiri, E., Moormann, A. M., King, C. L. (2008) Fine specificity of neonatal lymphocytes to an abundant malaria blood-stage antigen: epitope mapping of Plasmodium falciparum MSP1(33). J. Immunol. 180, 3383-3390.
    • (2008) J. Immunol , vol.180 , pp. 3383-3390
    • Malhotra, I.1    Wamachi, A.N.2    Mungai, P.L.3    Mzungu, E.4    Koech, D.5    Muchiri, E.6    Moormann, A.M.7    King, C.L.8


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