Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes

Blood

Volumn 114, Issue 9, 2009, Pages 1958-1967

  Hanley, Patrick J ^a   Cruz, Conrad Russell Young ^a   Savoldo, Barbara ^a   Leen, Ann M ^a   Stanojevic, Maja ^a   Khalil, Mariam ^a   Decker, William ^b   Molldrem, Jeffrey J ^b   Liu, Hao ^a   Gee, Adrian P ^a   Rooney, Cliona M ^a   Heslop, Helen E ^a   Dotti, Gianpietro ^a   Brenner, Malcolm K ^a   Shpall, Elizabeth J ^b   Bollard, Catherine M ^a  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR7; EPITOPE; PEPTIDE;

ADENOVIRUS; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL POPULATION; CONTROLLED STUDY; CYTOLYSIS; CYTOMEGALOVIRUS; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; EPSTEIN BARR VIRUS; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MEMORY CELL; PHENOTYPE; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; UMBILICAL CORD BLOOD; BIOLOGICAL MODEL; CHEMISTRY; CYTOLOGY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FETUS BLOOD; METABOLISM; MOTHER; T LYMPHOCYTE; VIROLOGY;

ADENOVIRIDAE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FETAL BLOOD; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOPHENOTYPING; MODELS, BIOLOGICAL; MOTHERS; PEPTIDES; PHENOTYPE; T-LYMPHOCYTES;

EID: 70349247010     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-03-213256     Document Type: Article

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