Identification of human T-lymphoid progenitor cells in CD34+CD38(low) and CD34+CD38+ subsets of human cord blood and bone marrow cells using NOD- SCID fetal thymus organ cultures

British Journal of Haematology

Volumn 104, Issue 4, 1999, Pages 809-819

  Robin, Catherine ^a   Bennaceur Griscelli, Annelise ^a   Louache, Fawzia ^a   Vainchenker, William ^a   Coulombel, Laure ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Cord blood; NOD SCID mice; Stem cells; T lymphopoiesis; Thymus

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN;

ARTICLE; BONE MARROW CELL; FETUS; HUMAN; MOUSE; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; STEM CELL; T LYMPHOCYTE SUBPOPULATION; THYMUS; UMBILICAL CORD BLOOD;

EID: 0033003612     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01266.x     Document Type: Article

References (43)

1. Akashi, K., Kondo, M., von Freeden-Jeffry, U., Murray, R. & Weissman, I.L. (1997) Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell, 89, 1033-1041.
2. Ball, T.C., Hirayama, F. & Ogawa, M. (1996) Modulation of early B lymphopoiesis by interleukin-3. Experimental Hematology, 24, 1225-1231.
3. - cells in human thymic organ culture. Journal of Experimental Medicine, 180, 123-132.
4. Barcena, A., Muench, M., Galy, A., Cupp, J., Grazia Roncarolo, M., Philips, J. & Spits, H. (1993) Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development. Blood, 82, 3401-3414.
5. Baum, C.M., Weissman, I.L., Tsukamoto, A.S., Buckle, A.-M. & Peault, B. (1992) Isolation of a candidate human hematopoietic stem-cell population. Proceedings of the National Academy of Sciences of the United States of America, 89, 2804-2808.
6. - progenitor cells from human cord blood generate B lymphocytes and granulocytes. Blood, 89, 3554-3564.
7. + progenitors capable of developing into T cells are not committed to the T cell lineage. Journal of Immunology, 158, 3571-3577.
8. Carayol, G., Robin, C., Bourhis, J.-H., Chouaib, S., Coulombel, L. & Caignard, A. (1998) Natural killer cells differentiated from bone marrow, cord blood and peripheral blood stem cells exhibit similar phenotype and functions. European Journal of Immunology, 28, 1991-2002.
9. Cashman, J.D., Lapidot, T., Wang, J.C., Doedens, M., Shultz, L.D., Lansdorp, P., Dick, J.E. & Eaves, C.J. (1997) Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood, 89, 4307-4316.
10. Conneally, E., Cashman, J., Petzer, A. & Eaves, C. (1997) Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice. Proceedings of the National Academy of Sciences of the United States of America, 94, 9836-9841.
11. - long-term culture-initiating cells. Blood, 84, 4116-4124.
12. DiGustio, D., Chen, S., Combs, J., Webb, S., Namikawa, R., Tsukamoto, A., Chen, B.P. & Galy, A.H. (1994) Human fetal bone marrow early progenitors for T, B and myeloid cells are found exclusively in the population expressing high levels of CD34. Blood, 84, 421-432.
13. Galy, A., Travis, M., Cen, D. & Chen, B. (1995a) Human T, B, Natural Killer and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity, 3, 459-473.
14. + compartment of adult bone marrow. Blood, 85, 2770-2778.
15. + cells. Blood, 84, 104-110.
16. - cells with both lymphoid and myeloid potential. Blood, 91, 4145-4151.
17. Hirayama, F. & Ogawa, M. (1995) Negative regulation of early T lymphopoiesis by interleukin-3 and interleukin-1. Blood, 86, 4527-4537.
18. +-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice. Blood, 90, 85-96.
19. - subset. Journal of Immunology, 146, 4078-4084.
20. Itoh, K., Tezuka, H., Sakoda, H., Konno, M., Nagata, K., Uchiyama, T., Uchino, H. & Mori, K.J. (1989) Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Experimental Hematology, 17, 145-153.
21. Jenkinson, E.J. & Anderson, G. (1994) Fetal thymic organ cultures. Current Opinion in Immunology, 6, 293-297.
22. Kawamoto, H., Ohmura, K. & Katsura, Y. (1997) Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver. International Immunology, 9, 1011-1019.
23. Kisielow, P. & Von Boehmer, H. (1995) Development and selection of T cells: facts and puzzles. Advances in Immunology, 58, 87-175.
24. Kollmann, T.R., Kim, A., Zhuang, X., Hachamovitch, M. & Goldstein, H. (1994) Reconstitution of SCID mice with human lymphoid and myeloid cells after transplantation with human fetal bone marrow without the requirement for exogenous human cytokines. Proceedings of the National Academy of Sciences of the United States of America, 91, 8032-8036.
25. Kondo, M., Weissman, I.L. & Akashi, K. (1997) Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell, 91, 661-672.
26. - intermediate. Journal of Experimental Medicine, 178, 265-277.
27. Lansdorp, P.M., Dragowska, W. & Mayani, H. (1993) Ontogeny-related changes in proliferative potential of human hematopoietic cells. Journal of Experimental Medicine, 178, 787-791.
28. bright progeny in organ culture. Journal of Immunology, 148, 1012-1015.
29. Pawliuk, R., Eaves, C. & Humphries, R.K. (1996) Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo. Blood, 88, 2852-2858.
30. + precursor cells. Journal of Experimental Medicine, 174, 1283-1286.
31. Pflumio, F., Izac, B., Katz, A., Shultz, L.D., Vainchenker, W. & Coulombel, L. (1996) Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells. Blood, 88, 3731-3740.
32. + fetal liver stem cells differentiate to T cells in a mouse thymic microenvironment. Blood, 84, 1587-1593.
33. - cord blood stem cells into B cell progenitors in vitro. Experimental Hematology, 25, 66-72.
34. dim cells in the human thymus can differentiate into T, natural killer and dendritic cells but are distinct from stem cells. Blood, 87, 5196-5206.
35. + progenitor cells. Blood, 87, 4040-4048.
36. Spits, H., Lanier, L. & Phillips, J. (1995) Development of human T and natural killer cells. Blood, 85, 2654-2670.
37. Sutherland, H., Eaves, C., Eaves, A., Dragowska, W. & Lansdorp, P. (1989) Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. Blood, 74, 1563-1570.
38. van der Loo, J.C., Hanenberg, H., Cooper, R.J., Luo, F.Y., Lazaridis, E.N. & Williams, D.A. (1998) Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mouse as a model system to study the engraftment and mobilization of human peripheral blood stem cells. Blood, 92, 2556-2570.
39. + + human cord blood cells generate T cells expressing high levels of the retroviral encoded green fluorescent protein marker in vitro. Blood, 91, 431-440.
40. Vormoor, J., Lapidot, T., Pflumio, F., Risdon, G., Patterson, B., Broxmeyer, H.E. & Dick, J.E. (1994) Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mouse. Blood, 83, 2489-2497.
41. Wang, J.C., Doedens, M. & Dick, J. (1997) Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay. Blood, 89, 3919-3924.
42. + single-positive T cells in murine fetal thymus organ culture. Immunology, 90, 10778-10782.
43. Yurasov, S., Kollman, T.R., Kim, A., Raker, C.A., Hachamovitch, M., Wong-staal, F. & Goldstein, H. (1997) Severe combined immunodeficiency mice engrafted with human T cells, B cells and myeloid cells after transplantation with human fetal bone marrow or liver cells and implanted with human fetal thymus: a model for studying human gene therapy. Blood, 89, 1800-1810.