메뉴 건너뛰기




Volumn 26, Issue 4, 2011, Pages 533-543

Salubrious effects of dexrazoxane against teniposide-induced DNA damage and programmed cell death in murine marrow cells

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLOPHOSPHAMIDE; GLUTATHIONE; RAZOXANE; REACTIVE OXYGEN METABOLITE; TENIPOSIDE;

EID: 79959737364     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ger013     Document Type: Article
Times cited : (41)

References (70)
  • 1
    • 0030014783 scopus 로고    scopus 로고
    • DNA topoisomerases
    • Wang, J. C. (1996) DNA topoisomerases. Annu. Rev. Biochem., 65, 635-692.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 635-692
    • Wang, J.C.1
  • 2
    • 0036287867 scopus 로고    scopus 로고
    • DNA topoisomerase II as a target for cancer chemotherapy
    • Walker, J. V. and Nitiss, J. L. (2002) DNA topoisomerase II as a target for cancer chemotherapy. Cancer Invest., 20, 570-589.
    • (2002) Cancer Invest. , vol.20 , pp. 570-589
    • Walker, J.V.1    Nitiss, J.L.2
  • 3
    • 33749658088 scopus 로고    scopus 로고
    • Topoisomerase enzymes as therapeutic targets for cancer chemotherapy
    • Giles, G. I. and Sharma, R. P. (2005) Topoisomerase enzymes as therapeutic targets for cancer chemotherapy. Med. Chem., 1, 383-394.
    • (2005) Med. Chem. , vol.1 , pp. 383-394
    • Giles, G.I.1    Sharma, R.P.2
  • 4
    • 0042346439 scopus 로고    scopus 로고
    • Catalytic topoisomerase II inhibitors in cancer therapy
    • Larsen, A. K., Escargueil, A. E. and Skladanowski, A. (2003) Catalytic topoisomerase II inhibitors in cancer therapy. Pharmacol. Ther., 99, 167-181.
    • (2003) Pharmacol. Ther. , vol.99 , pp. 167-181
    • Larsen, A.K.1    Escargueil, A.E.2    Skladanowski, A.3
  • 5
    • 20944449940 scopus 로고    scopus 로고
    • Toxicity of the topoisomerase II inhibitors
    • Seiter, K. (2005) Toxicity of the topoisomerase II inhibitors. Expert Opin. Drug Saf., 4, 219-234.
    • (2005) Expert Opin. Drug Saf. , vol.4 , pp. 219-234
    • Seiter, K.1
  • 6
    • 0034034557 scopus 로고    scopus 로고
    • Topoisomerase II inhibitor-related acute myeloid leukemia
    • Pui, C. H. and Relling, M. V. (2000) Topoisomerase II inhibitor-related acute myeloid leukemia. Br. J. Haematol., 109, 13-23.
    • (2000) Br. J. Haematol. , vol.109 , pp. 13-23
    • Pui, C.H.1    Relling, M.V.2
  • 7
    • 31344454019 scopus 로고    scopus 로고
    • Genotoxicity of etoposide: Greater susceptibility of MLL than other target genes
    • Ng, A., Taylor, G. M. and Eden, O. B. (2006) Genotoxicity of etoposide: greater susceptibility of MLL than other target genes. Cancer Genet. Cytogenet., 164, 164-167.
    • (2006) Cancer Genet. Cytogenet. , vol.164 , pp. 164-167
    • Ng, A.1    Taylor, G.M.2    Eden, O.B.3
  • 8
    • 39749126990 scopus 로고    scopus 로고
    • Mutagenicity of some topoisomerase II-interactive agents
    • Attia, S. M. (2008) Mutagenicity of some topoisomerase II-interactive agents. SPJ, 17, 1-24.
    • (2008) SPJ , vol.17 , pp. 1-24
    • Attia, S.M.1
  • 9
    • 0035432094 scopus 로고    scopus 로고
    • Secondary acute myelocytic leukemia after successful chemotherapy with etoposide for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
    • Kitazawa, J., Ito, E., Arai, K., Yokoyama, M., Fukayama, M. and Imashuku, S. (2001) Secondary acute myelocytic leukemia after successful chemotherapy with etoposide for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Med. Pediatr. Oncol., 37, 153-154.
    • (2001) Med. Pediatr. Oncol. , vol.37 , pp. 153-154
    • Kitazawa, J.1    Ito, E.2    Arai, K.3    Yokoyama, M.4    Fukayama, M.5    Imashuku, S.6
  • 10
    • 33747892853 scopus 로고    scopus 로고
    • Topoisomerase II and the etiology of chromosomal translocations
    • DOI 10.1016/j.dnarep.2006.05.031, PII S1568786406001716, Mechanisms of Chromosomal Translocations
    • Felix, C. A., Kolaris, C. P. and Osheroff, N. (2006) Topoisomerase II and the etiology of chromosomal translocations. DNA Repair (Amst.), 5, 1093-1108. (Pubitemid 44291622)
    • (2006) DNA Repair , vol.5 , Issue.9-10 , pp. 1093-1108
    • Felix, C.A.1    Kolaris, C.P.2    Osheroff, N.3
  • 11
    • 0034974659 scopus 로고    scopus 로고
    • Increased aneuploidy in spermatozoa from testicular tumour patients after chemotherapy with cisplatin, etoposide and bleomycin
    • De Mas, P., Daudin, M., Vincent, M. C., Bourrouillou, G., Calvas, P., Mieusset, R. and Bujan, L. (2001) Increased aneuploidy in spermatozoa from testicular tumour patients after chemotherapy with cisplatin, etoposide and bleomycin. Hum. Reprod., 16, 1204-1208. (Pubitemid 32544692)
    • (2001) Human Reproduction , vol.16 , Issue.6 , pp. 1204-1208
    • De Mas, P.1    Daudin, M.2    Vincent, M.-C.3    Bourrouillou, G.4    Calvas, P.5    Mieusset, R.6    Bujan, L.7
  • 12
    • 0023251854 scopus 로고
    • Etoposide (VP16) and teniposide (VM26): Novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems
    • Gupta, R. S., Bromke, A., Bryant, D. W., Gupta, R., Singh, B. and McCalla, D. R. (1987) Etoposide (VP16) and teniposide (VM26): novel anticancer drugs, strongly mutagenic in mammalian but not prokaryotic test systems. Mutagenesis, 2, 179-186.
    • (1987) Mutagenesis , vol.2 , pp. 179-186
    • Gupta, R.S.1    Bromke, A.2    Bryant, D.W.3    Gupta, R.4    Singh, B.5    McCalla, D.R.6
  • 13
    • 0032990676 scopus 로고    scopus 로고
    • Elevation of micronuclei frequency in mouse bone marrow treated with various doses of teniposide (VM-26)
    • DOI 10.1016/S0378-4274(98)00368-3, PII S0378427498003683
    • Jagetia, G. C. and Aruna, R. (1999) Elevation of micronuclei frequency in mouse bone marrow treated with various doses of teniposide (VM-26). Toxicol. Lett., 104, 203-210. (Pubitemid 29078663)
    • (1999) Toxicology Letters , vol.104 , Issue.3 , pp. 203-210
    • Jagetia, G.C.1    Aruna, R.2
  • 14
    • 0037179507 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis in mouse sperm of chemically induced aneuploidy: Studies with topoisomerase II inhibitors
    • Attia, S. M., Schmid, T. E., Badary, O. A., Hamada, F. M. and Adler, I.-D. (2002) Molecular cytogenetic analysis in mouse sperm of chemically induced aneuploidy: studies with topoisomerase II inhibitors. Mutat. Res., 520, 1-13.
    • (2002) Mutat. Res. , vol.520 , pp. 1-13
    • Attia, S.M.1    Schmid, T.E.2    Badary, O.A.3    Hamada, F.M.4    Adler, I.-D.5
  • 15
    • 0037225813 scopus 로고    scopus 로고
    • Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe
    • Attia, S. M. Kliesch, U., Schriever-Schwemmer, G., Badary, O. A., Hamada, F. M. and Adler, I.-D. (2003) Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe. Environ. Mol. Mutagen., 41, 99-103.
    • (2003) Environ. Mol. Mutagen. , vol.41 , pp. 99-103
    • Attia, S.M.1    Kliesch, U.2    Schriever-Schwemmer, G.3    Badary, O.A.4    Hamada, F.M.5    Adler, I.-D.6
  • 16
    • 33644806519 scopus 로고    scopus 로고
    • Protecting against anthracycline-induced myocardial damage: A review of the most promising strategies
    • Wouters, K. A., Kremer, L. C., Miller, T. L., Herman, E. H. and Lipshultz, S. E. (2005) Protecting against anthracycline-induced myocardial damage: a review of the most promising strategies. Br. J. Haematol., 131, 561-578.
    • (2005) Br. J. Haematol. , vol.131 , pp. 561-578
    • Wouters, K.A.1    Kremer, L.C.2    Miller, T.L.3    Herman, E.H.4    Lipshultz, S.E.5
  • 17
    • 0029796045 scopus 로고    scopus 로고
    • The effect of dexrazoxane (ICRF-187) on doxorubicin- And daunorubicin-mediated growth inhibition of Chinese hamster ovary cells
    • Hasinoff, B. B., Yalowich, J. C., Ling, Y. and Buss, J. L. (1996) The effect of dexrazoxane (ICRF-187) on doxorubicin- and daunorubicin-mediated growth inhibition of Chinese hamster ovary cells. Anticancer Drugs, 7, 558-567.
    • (1996) Anticancer Drugs , vol.7 , pp. 558-567
    • Hasinoff, B.B.1    Yalowich, J.C.2    Ling, Y.3    Buss, J.L.4
  • 18
    • 0037411223 scopus 로고    scopus 로고
    • Dexrazoxane in combination with anthracyclines lead to a synergistic cytotoxic response in acute myelogenous leukemia cell lines
    • Pearlman, M., Jendiroba, D., Pagliaro, L., Keyhani, A., Liu, B. and Freireich, E. J. (2003) Dexrazoxane in combination with anthracyclines lead to a synergistic cytotoxic response in acute myelogenous leukemia cell lines. Leuk. Res., 27, 617-626.
    • (2003) Leuk. Res. , vol.27 , pp. 617-626
    • Pearlman, M.1    Jendiroba, D.2    Pagliaro, L.3    Keyhani, A.4    Liu, B.5    Freireich, E.J.6
  • 19
    • 0031802032 scopus 로고    scopus 로고
    • Improved targeting of brain tumors using dexrazoxane rescue of topoisomerase II combined with supralethal doses of etoposide and teniposide
    • Holm, B., Sehested, M. and Jensen, P. B. (1998) Improved targeting of brain tumors using dexrazoxane rescue of topoisomerase II combined with supralethal doses of etoposide and teniposide. Clin. Cancer Res., 4, 1367-1373.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1367-1373
    • Holm, B.1    Sehested, M.2    Jensen, P.B.3
  • 21
    • 18844462177 scopus 로고    scopus 로고
    • Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin
    • Hofland, K. F., Thougaard, A. V., Sehested, M. and Jensen, P. B. (2005) Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin. Clin. Cancer Res., 11, 3915-3924.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3915-3924
    • Hofland, K.F.1    Thougaard, A.V.2    Sehested, M.3    Jensen, P.B.4
  • 23
    • 55349087274 scopus 로고    scopus 로고
    • Abatement by naringin of lomefloxacin-induced genomic instability in mice
    • Attia, S. M. (2008) Abatement by naringin of lomefloxacin-induced genomic instability in mice. Mutagenesis, 23, 515-521.
    • (2008) Mutagenesis , vol.23 , pp. 515-521
    • Attia, S.M.1
  • 24
    • 0000270239 scopus 로고
    • Cytogenetic tests in mammals
    • Venitt, S. and Parry, J. M. (eds), IRI Press, Oxford
    • Adler, I.-D. (1984) Cytogenetic tests in mammals. In Venitt, S. and Parry, J. M. (eds), Mutagenicity Testing: A Practical Approach. IRI Press, Oxford, pp. 275-306.
    • (1984) Mutagenicity Testing: A Practical Approach , pp. 275-306
    • Adler, I.-D.1
  • 25
    • 0034037611 scopus 로고    scopus 로고
    • Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing
    • Tice, R. R., Agurell, E., Anderson, D. et al. (2000) Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen., 35, 206-221.
    • (2000) Environ. Mol. Mutagen. , vol.35 , pp. 206-221
    • Tice, R.R.1    Agurell, E.2    Anderson, D.3
  • 26
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F. and Riccardi, C. (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods, 139, 271-279.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 27
    • 77951965597 scopus 로고    scopus 로고
    • The impact of quercetin on cisplatin-induced clastogenesis and apoptosis in murine marrow cells
    • Attia, S. M. (2010) The impact of quercetin on cisplatin-induced clastogenesis and apoptosis in murine marrow cells. Mutagenesis, 25, 281-288.
    • (2010) Mutagenesis , vol.25 , pp. 281-288
    • Attia, S.M.1
  • 28
    • 0030964037 scopus 로고    scopus 로고
    • ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha
    • Kunstle, G., Leist, M., Uhlig, S., Revesz, L., Feifel, R., MacKenzie, A. and Wendel, A. (1997) ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha. Immunol. Lett., 55, 5-10.
    • (1997) Immunol. Lett. , vol.55 , pp. 5-10
    • Kunstle, G.1    Leist, M.2    Uhlig, S.3    Revesz, L.4    Feifel, R.5    MacKenzie, A.6    Wendel, A.7
  • 29
    • 0041733598 scopus 로고    scopus 로고
    • Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: Roles of cytochrome c, Bax, Bid, and caspases
    • El-Hassan, H., Anwar, K., Macanas-Pirard, P. et al. (2003) Involvement of mitochondria in acetaminophen-induced apoptosis and hepatic injury: roles of cytochrome c, Bax, Bid, and caspases. Toxicol. Appl. Pharmacol., 191, 118-129.
    • (2003) Toxicol. Appl. Pharmacol. , vol.191 , pp. 118-129
    • El-Hassan, H.1    Anwar, K.2    Macanas-Pirard, P.3
  • 31
    • 2942572700 scopus 로고    scopus 로고
    • Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean?
    • DOI 10.1038/sj.bjp.0705776
    • Halliwell, B. and Whiteman, M. (2004) Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br. J. Pharmacol., 142, 231-255. (Pubitemid 38746160)
    • (2004) British Journal of Pharmacology , vol.142 , Issue.2 , pp. 231-255
    • Halliwell, B.1    Whiteman, M.2
  • 32
    • 0018384650 scopus 로고
    • Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa, H., Ohishi, N. and Yagi, K. (1979) Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem., 95, 351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 33
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman, G. L. (1959) Tissue sulfhydryl groups. Arch. Biochem. Biophys., 82, 70-77.
    • (1959) Arch. Biochem. Biophys. , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 34
    • 0022272493 scopus 로고
    • Determination of glutathione and glutathione disulfide in biological samples
    • Meister, A. (ed.), Academic Press, NY, USA
    • Anderson, M. E. (1985) Determination of glutathione and glutathione disulfide in biological samples. In Meister, A. (ed.), Methods Enzymology, 113. Academic Press, NY, USA, pp. 548-555.
    • (1985) Methods Enzymology , vol.113 , pp. 548-555
    • Anderson, M.E.1
  • 35
    • 33746314590 scopus 로고    scopus 로고
    • Cypermethrin-induced DNA damage in organs and tissues of the mouse: Evidence from the comet assay
    • Patel, S., Pandey, A. K., Bajpayee, M., Parmar, D. and Dhawan, A. (2006) Cypermethrin-induced DNA damage in organs and tissues of the mouse: evidence from the comet assay. Mutat. Res., 607, 176-183.
    • (2006) Mutat. Res. , vol.607 , pp. 176-183
    • Patel, S.1    Pandey, A.K.2    Bajpayee, M.3    Parmar, D.4    Dhawan, A.5
  • 36
    • 0017816035 scopus 로고
    • Teratogenic and cytogenetic effects of some plant-derived antitumor agents (vincristine, colchicine, maytansine, VP-16-213 and VM-26) in mice
    • Sieber, S. M., Whang-Peng, J., Botkin, C. and Knutsen, T. (1978) Teratogenic and cytogenetic effects of some plant-derived antitumor agents (vincristine, colchicine, maytansine, VP-16 and VM-26) in mice. Teratology, 18, 31-47. (Pubitemid 8397605)
    • (1978) Teratology , vol.18 , Issue.1 , pp. 31-47
    • Sieber, S.M.1    Whang, P.J.2    Botkin, C.3    Knutsen, T.4
  • 37
    • 0030988121 scopus 로고    scopus 로고
    • Detection of chemically induced DNA lesions in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow) using the alkaline single cell gel electrophoresis (Comet) assay
    • Sasaki, Y. F., Tsuda, S., Izumiyama, F. and Nishidate, E. (1997) Detection of chemically induced DNA lesions in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow) using the alkaline single cell gel electrophoresis (Comet) assay. Mutat. Res., 388, 33-44.
    • (1997) Mutat. Res. , vol.388 , pp. 33-44
    • Sasaki, Y.F.1    Tsuda, S.2    Izumiyama, F.3    Nishidate, E.4
  • 39
    • 0028933380 scopus 로고
    • Differences in inhibition of chromosome separation and G2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26
    • Chen, M. and Beck, W. T. (1995) Differences in inhibition of chromosome separation and G2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26. Cancer Res., 55, 1509-1516.
    • (1995) Cancer Res. , vol.55 , pp. 1509-1516
    • Chen, M.1    Beck, W.T.2
  • 40
    • 0027214092 scopus 로고
    • Antagonistic effect of the cardioprotector (+)-1,2- Bis(3,5- dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16)
    • Sehested, M., Jensen, P. B., Sørensen, B. S., Holm, B., Friche, E. and Demant, E. J. (1993) Antagonistic effect of the cardioprotector (+)-1,2- bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16). Biochem. Pharmacol., 46, 389-393.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 389-393
    • Sehested, M.1    Jensen, P.B.2    Sørensen, B.S.3    Holm, B.4    Friche, E.5    Demant, E.J.6
  • 41
    • 33747333594 scopus 로고    scopus 로고
    • Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma
    • Li, J., Chen, W., Zhang, P. and Li, N. (2006) Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma. World J. Surg. Oncol., 4, 41.
    • (2006) World J. Surg. Oncol. , vol.4 , pp. 41
    • Li, J.1    Chen, W.2    Zhang, P.3    Li, N.4
  • 42
  • 43
    • 0028146085 scopus 로고
    • In vivo inhibition of etoposide-mediated apoptosis, toxicity, and antitumor effect by the topoisomerase II-uncoupling anthracycline aclarubicin
    • Holm, B., Jensen, P. B., Sehested, M. and Hansen, H. H. (1994) In vivo inhibition of etoposide-mediated apoptosis, toxicity, and antitumor effect by the topoisomerase II-uncoupling anthracycline aclarubicin. Cancer Chemother. Pharmacol., 34, 503-508.
    • (1994) Cancer Chemother. Pharmacol. , vol.34 , pp. 503-508
    • Holm, B.1    Jensen, P.B.2    Sehested, M.3    Hansen, H.H.4
  • 44
    • 0041854306 scopus 로고    scopus 로고
    • The metabolites of the cardioprotective drug dexrazoxane do not protect myocytes from doxorubicin-induced cytotoxicity
    • Hasinoff, B. B., Schroeder, P. E. and Patel, D. (2003) The metabolites of the cardioprotective drug dexrazoxane do not protect myocytes from doxorubicin-induced cytotoxicity. Mol. Pharmacol., 64, 670-678.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 670-678
    • Hasinoff, B.B.1    Schroeder, P.E.2    Patel, D.3
  • 45
    • 0033014821 scopus 로고    scopus 로고
    • Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane
    • Sawyer, D. B., Fukazawa, R., Arstall, M. A. and Kelly, R. A. (1999) Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane. Circ. Res., 84, 257-265.
    • (1999) Circ. Res. , vol.84 , pp. 257-265
    • Sawyer, D.B.1    Fukazawa, R.2    Arstall, M.A.3    Kelly, R.A.4
  • 46
    • 70249126852 scopus 로고    scopus 로고
    • Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: Effective rescue of cardiomyocytes from apoptotic cell death
    • Popelová, O., Sterba, M., Hasková, P. et al. (2009) Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death. Br. J. Cancer, 101, 792-802.
    • (2009) Br. J. Cancer , vol.101 , pp. 792-802
    • Popelová, O.1    Sterba, M.2    Hasková, P.3
  • 47
    • 0028810791 scopus 로고
    • A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane)
    • Hasinoff, B. B., Kuschak, T. I., Yalowich, J. C. and Creighton, A. M. (1995) A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane). Biochem. Pharmacol., 50, 953-958.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 953-958
    • Hasinoff, B.B.1    Kuschak, T.I.2    Yalowich, J.C.3    Creighton, A.M.4
  • 48
    • 0022536877 scopus 로고
    • Peroxidative free radical formation and O-demethylation of etoposide(VP-16) and teniposide(VM-26)
    • Haim, N., Roman, J., Nemec, J. and Sinha, B. K. (1986) Peroxidative free radical formation and O-demethylation of etoposide(VP-16) and teniposide(VM-26). Biochem. Biophys. Res. Commun., 135, 215-220.
    • (1986) Biochem. Biophys. Res. Commun. , vol.135 , pp. 215-220
    • Haim, N.1    Roman, J.2    Nemec, J.3    Sinha, B.K.4
  • 49
    • 0023235581 scopus 로고
    • The clinical pharmacology of etoposide and teniposide
    • Clark, P. I. and Slevin, M. L. (1987) The clinical pharmacology of etoposide and teniposide. Clin Pharmacokinet., 12, 223-252.
    • (1987) Clin Pharmacokinet. , vol.12 , pp. 223-252
    • Clark, P.I.1    Slevin, M.L.2
  • 50
    • 0023841118 scopus 로고
    • Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16
    • DOI 10.1016/0014-5793(88)80906-2
    • Sinha, B. K., Eliot, H. M. and Kalayanaraman, B. (1988) Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16. FEBS Lett., 227, 240-244. (Pubitemid 18033882)
    • (1988) FEBS Letters , vol.227 , Issue.2 , pp. 240-244
    • Sinha, B.K.1    Eliot, H.M.2    Kalayanaraman, B.3
  • 51
    • 0024372292 scopus 로고
    • Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives: An ESR Study
    • Kalyanaraman, B., Nemec, J. and Sinha, B. K. (1989) Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives: an ESR Study. Biochemistry, 28, 4839-4846.
    • (1989) Biochemistry , vol.28 , pp. 4839-4846
    • Kalyanaraman, B.1    Nemec, J.2    Sinha, B.K.3
  • 52
    • 0024332110 scopus 로고
    • Effect of etoposide (VP16-213) on lipid peroxidation and antioxidant status in a high-dose radiochemotherapy regimen
    • Ladner, C., Ehninger, G., Gey, K. F. and Clemens, M. R. (1989) Effect of etoposide (VP16-213) on lipid peroxidation and antioxidant status in a high-dose radiochemotherapy regimen. Cancer Chemother. Pharmacol., 25, 210-212.
    • (1989) Cancer Chemother. Pharmacol. , vol.25 , pp. 210-212
    • Ladner, C.1    Ehninger, G.2    Gey, K.F.3    Clemens, M.R.4
  • 53
    • 0032529637 scopus 로고    scopus 로고
    • Apoptosis, reproductive failure, and oxidative stress in Chinese hamster ovary cells with compromised genomic integrity
    • Limoli, C. L., Hartmann, A., Shephard, L., Yang, C. R., Boothman, D. A., Bartholomew, J. and Morgan, W. F. (1998) Apoptosis, reproductive failure, and oxidative stress in Chinese hamster ovary cells with compromised genomic integrity. Cancer Res., 58, 3712-3718.
    • (1998) Cancer Res. , vol.58 , pp. 3712-3718
    • Limoli, C.L.1    Hartmann, A.2    Shephard, L.3    Yang, C.R.4    Boothman, D.A.5    Bartholomew, J.6    Morgan, W.F.7
  • 54
    • 0026851952 scopus 로고
    • Mechanisms of action of teniposide (VM-26) and comparison with etoposide (VP-16)
    • Long, B. H. (1992) Mechanisms of action of teniposide (VM-26) and comparison with etoposide (VP-16). Semin. Oncol., 19, 3-19.
    • (1992) Semin. Oncol. , vol.19 , pp. 3-19
    • Long, B.H.1
  • 55
    • 0026522710 scopus 로고
    • Reactions of glutathione with the catechol, the ortho-quinone and the semiquinone free radical of etoposide. Consequences for DNA inactivation
    • Mans, D. R., Lafleur, M. V., Westmijze, E. J., Horn, I. R., Bets, D., Schuurhuis, G. J., Lankelma, J. and Retèl, J. (1992) Reactions of glutathione with the catechol, the ortho-quinone and the semiquinone free radical of etoposide. Consequences for DNA inactivation. Biochem. Pharmacol., 43, 1761-1768.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 1761-1768
    • Mans, D.R.1    Lafleur, M.V.2    Westmijze, E.J.3    Horn, I.R.4    Bets, D.5    Schuurhuis, G.J.6    Lankelma, J.7    Retèl, J.8
  • 56
    • 0029089072 scopus 로고
    • Antioxidant paradoxes of phenolic compounds: Peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical
    • Ritov, V. B., Goldman, R., Stoyanovsky, D. A., Menshikova, E. V. and Kagan, V. E. (1995) Antioxidant paradoxes of phenolic compounds: peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical. Arch. Biochem. Biophys., 321, 140-152.
    • (1995) Arch. Biochem. Biophys. , vol.321 , pp. 140-152
    • Ritov, V.B.1    Goldman, R.2    Stoyanovsky, D.A.3    Menshikova, E.V.4    Kagan, V.E.5
  • 57
    • 77953384917 scopus 로고    scopus 로고
    • Redox regulation in cancer: A double-edged sword with therapeutic potential
    • Acharya, A., Das, I., Chandhok, D. and Saha, T. (2010) Redox regulation in cancer: a double-edged sword with therapeutic potential. Oxid. Med. Cell. Longev., 3, 23-34.
    • (2010) Oxid. Med. Cell. Longev. , vol.3 , pp. 23-34
    • Acharya, A.1    Das, I.2    Chandhok, D.3    Saha, T.4
  • 58
    • 77957362113 scopus 로고    scopus 로고
    • Deleterious effects of reactive metabolites
    • Attia, S. M. (2010) Deleterious effects of reactive metabolites. Oxid. Med. Cell. Longev., 3, 238-253.
    • (2010) Oxid. Med. Cell. Longev. , vol.3 , pp. 238-253
    • Attia, S.M.1
  • 59
    • 34447573788 scopus 로고    scopus 로고
    • Dexrazoxane prevents doxorubicin-induced longterm cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats
    • Lebrecht, D., Geist, A., Ketelsen, U. P., Haberstroh, J., Setzer, B. and Walker, U. A. (2007) Dexrazoxane prevents doxorubicin-induced longterm cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats. Br. J. Pharmacol., 151, 771-778.
    • (2007) Br. J. Pharmacol. , vol.151 , pp. 771-778
    • Lebrecht, D.1    Geist, A.2    Ketelsen, U.P.3    Haberstroh, J.4    Setzer, B.5    Walker, U.A.6
  • 60
    • 34548299563 scopus 로고    scopus 로고
    • Dexrazoxane: How it works in cardiac and tumor cells. Is it a prodrug or is it a drug?
    • Hasinoff, B. B. and Herman, E. H. (2007) Dexrazoxane: how it works in cardiac and tumor cells. Is it a prodrug or is it a drug? Cardiovasc. Toxicol., 7, 140-144.
    • (2007) Cardiovasc. Toxicol. , vol.7 , pp. 140-144
    • Hasinoff, B.B.1    Herman, E.H.2
  • 61
    • 78049486401 scopus 로고    scopus 로고
    • Scavenging effects of dexrazoxane on free radicals
    • Junjing, Z., Yan, Z. and Baolu, Z. (2010) Scavenging effects of dexrazoxane on free radicals. J. Clin. Biochem. Nutr., 47, 238-245.
    • (2010) J. Clin. Biochem. Nutr. , vol.47 , pp. 238-245
    • Junjing, Z.1    Yan, Z.2    Baolu, Z.3
  • 62
    • 77952319706 scopus 로고    scopus 로고
    • In vitro and in vivo study on the antioxidant activity of dexrazoxane
    • Galetta, F., Franzoni, F., Cervetti, G. et al. (2010) In vitro and in vivo study on the antioxidant activity of dexrazoxane. Biomed. Pharmacother., 64, 259-263.
    • (2010) Biomed. Pharmacother. , vol.64 , pp. 259-263
    • Galetta, F.1    Franzoni, F.2    Cervetti, G.3
  • 64
    • 0027943694 scopus 로고
    • The pharmacokinetics of high-dose epirubicin and of the cardioprotector ADR-529 given together with cyclophosphamide, 5-fluorouracil, and tamoxifen in metastatic breast cancer patients
    • Jakobsen, P., Sorensen, B., Bastholt, L., Mirza, M. R., Gjedde, S. B., Mouridsen, H. T. and Rose, C. (1994) The pharmacokinetics of high-dose epirubicin and of the cardioprotector ADR-529 given together with cyclophosphamide, 5-fluorouracil, and tamoxifen in metastatic breast cancer patients. Cancer Chemother. Pharmacol., 35, 45-52.
    • (1994) Cancer Chemother. Pharmacol. , vol.35 , pp. 45-52
    • Jakobsen, P.1    Sorensen, B.2    Bastholt, L.3    Mirza, M.R.4    Gjedde, S.B.5    Mouridsen, H.T.6    Rose, C.7
  • 66
    • 0742286817 scopus 로고    scopus 로고
    • Pharmacokinetics of etoposide in cancer patients treated with high-dose etoposide and with dexrazoxane (ICRF-187) as a rescue agent
    • Schroeder, P. E., Hofland, K. F., Jensen, P. B., Sehested, M., Langer, S. W. and Hasinoff, B. B. (2004) Pharmacokinetics of etoposide in cancer patients treated with high-dose etoposide and with dexrazoxane (ICRF-187) as a rescue agent. Cancer Chemother. Pharmacol., 53, 91-93.
    • (2004) Cancer Chemother. Pharmacol. , vol.53 , pp. 91-93
    • Schroeder, P.E.1    Hofland, K.F.2    Jensen, P.B.3    Sehested, M.4    Langer, S.W.5    Hasinoff, B.B.6
  • 68
    • 0035067840 scopus 로고    scopus 로고
    • Dexrazoxane is a potent and specific inhibitor of anthracycline induced subcutaneous lesions in mice
    • Langer, S. W., Sehested, M. and Jensen, P. B. (2001) Dexrazoxane is a potent and specific inhibitor of anthracycline induced subcutaneous lesions in mice. Ann. Oncol., 12, 405-410.
    • (2001) Ann. Oncol. , vol.12 , pp. 405-410
    • Langer, S.W.1    Sehested, M.2    Jensen, P.B.3
  • 69
    • 0742269397 scopus 로고    scopus 로고
    • The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: Expert panel review
    • Swain, S. M. and Vici, P. (2004) The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: expert panel review. J. Cancer Res. Clin. Oncol., 130, 1-7.
    • (2004) J. Cancer Res. Clin. Oncol. , vol.130 , pp. 1-7
    • Swain, S.M.1    Vici, P.2
  • 70
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti, G., Menna, P., Salvatorelli, E., Cairo, G. and Gianni, L. (2004) Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev., 56, 185-229.
    • (2004) Pharmacol. Rev. , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.