메뉴 건너뛰기




Volumn 64, Issue 4, 2010, Pages 259-263

In vitro and in vivo study on the antioxidant activity of dexrazoxane

Author keywords

Anthracyclines; Antioxidants; Dexrazoxane; Epirubicin; Free radicals

Indexed keywords

BLEOMYCIN; CYCLOPHOSPHAMIDE; CYTARABINE; EPIRUBICIN; ETOPOSIDE; FREE RADICAL; GLUTATHIONE; METHOTREXATE; PREDNISOLONE; RAZOXANE; TROLOX C; URIC ACID; VINCRISTINE;

EID: 77952319706     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2009.06.018     Document Type: Article
Times cited : (21)

References (31)
  • 1
    • 0017108045 scopus 로고
    • Cardiotoxicity of adriamycin and related anthracyclines
    • Lenaz L., Page J. Cardiotoxicity of adriamycin and related anthracyclines. Cancer Treat Rev 1976, 3:111-120.
    • (1976) Cancer Treat Rev , vol.3 , pp. 111-120
    • Lenaz, L.1    Page, J.2
  • 2
    • 0015849162 scopus 로고
    • A clinicopathologic analysis of doxorubicin cardiotoxicity
    • Lefrak E.A., Pitha J., Rosenheim S., Gottlieb J.A. A clinicopathologic analysis of doxorubicin cardiotoxicity. Cancer 1973, 32:302-314.
    • (1973) Cancer , vol.32 , pp. 302-314
    • Lefrak, E.A.1    Pitha, J.2    Rosenheim, S.3    Gottlieb, J.A.4
  • 3
    • 0031660433 scopus 로고    scopus 로고
    • Epidemiology of anthracycline cardiotoxicity in children and adults
    • Grenier M.A., Lipshultz S.E. Epidemiology of anthracycline cardiotoxicity in children and adults. Semin Oncol 1998, 25:72-85.
    • (1998) Semin Oncol , vol.25 , pp. 72-85
    • Grenier, M.A.1    Lipshultz, S.E.2
  • 4
    • 18444416815 scopus 로고    scopus 로고
    • Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia
    • Lipshultz S.E., Lipsitz S.R., Sallan S.E., Dalton V.M., Mone S.M., Gelber R.D., et al. Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia. J Clin Oncol 2005, 23:2629-2636.
    • (2005) J Clin Oncol , vol.23 , pp. 2629-2636
    • Lipshultz, S.E.1    Lipsitz, S.R.2    Sallan, S.E.3    Dalton, V.M.4    Mone, S.M.5    Gelber, R.D.6
  • 5
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: analysis of prevailing hypothesis
    • Olson R., Mushlin P. Doxorubicin cardiotoxicity: analysis of prevailing hypothesis. FASEB J 1990, 4:3076-3086.
    • (1990) FASEB J , vol.4 , pp. 3076-3086
    • Olson, R.1    Mushlin, P.2
  • 6
    • 34447573788 scopus 로고    scopus 로고
    • Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats
    • Lebrecht D., Geist A., Ketelsen J., Setter B., Walzer U.A. Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats. Br J Pharmacol 2007, 151:771-778.
    • (2007) Br J Pharmacol , vol.151 , pp. 771-778
    • Lebrecht, D.1    Geist, A.2    Ketelsen, J.3    Setter, B.4    Walzer, U.A.5
  • 7
    • 33745130622 scopus 로고
    • Characterization of the cycle of iron-mediated electron transfer from doxorubicin to molecular oxygen
    • Gianni L., Zweier J., Levy A., Meyers C.E. Characterization of the cycle of iron-mediated electron transfer from doxorubicin to molecular oxygen. J Biol Chem 1985, 259:6056-6058.
    • (1985) J Biol Chem , vol.259 , pp. 6056-6058
    • Gianni, L.1    Zweier, J.2    Levy, A.3    Meyers, C.E.4
  • 8
    • 0025212158 scopus 로고
    • Dl-N,N'-dicarboxamidomethyl-N,N'-dicarboxy methyl-1,2-diaminopropane (ICRF-198) and d-1,2-bis(3,5-dioxopiperazine- 1-yl)propane (ICRF-187) inhibition of Fe3+ reduction, lipid peroxidation, and CaATPase inactivation in heart microsomes exposed to adriamycin
    • Vile G.F., Winterbourn C.C. dl-N,N'-dicarboxamidomethyl-N,N'-dicarboxy methyl-1,2-diaminopropane (ICRF-198) and d-1,2-bis(3,5-dioxopiperazine- 1-yl)propane (ICRF-187) inhibition of Fe3+ reduction, lipid peroxidation, and CaATPase inactivation in heart microsomes exposed to adriamycin. Cancer Res 1990, 50:2307-2310.
    • (1990) Cancer Res , vol.50 , pp. 2307-2310
    • Vile, G.F.1    Winterbourn, C.C.2
  • 9
    • 18744377282 scopus 로고    scopus 로고
    • Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy
    • Cvetković R.S., Scott L.J. Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy. Drugs 2005, 65:1005-1024.
    • (2005) Drugs , vol.65 , pp. 1005-1024
    • Cvetković, R.S.1    Scott, L.J.2
  • 10
    • 7544243756 scopus 로고    scopus 로고
    • Evaluating the role of dexrazoxane as a cardioprotectant in cancer patients receiving anthracyclines
    • Pouillart P. Evaluating the role of dexrazoxane as a cardioprotectant in cancer patients receiving anthracyclines. Cancer Treat Rev 2004, 30:643-650.
    • (2004) Cancer Treat Rev , vol.30 , pp. 643-650
    • Pouillart, P.1
  • 12
    • 0030904096 scopus 로고    scopus 로고
    • Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer
    • Swain S.M., Whaley F.S., Gerber M.C., Weisberg S., York M., Spicer D., et al. Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer. J Clin Oncol 1997, 15:1318-1332.
    • (1997) J Clin Oncol , vol.15 , pp. 1318-1332
    • Swain, S.M.1    Whaley, F.S.2    Gerber, M.C.3    Weisberg, S.4    York, M.5    Spicer, D.6
  • 13
    • 0030991044 scopus 로고    scopus 로고
    • Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy
    • Swain S.M., Whaley F.S., Gerber M.C., Ewer M.S., Bianchine J.R., Gams R.A. Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy. J Clin Oncol 1997, 15:1333-1340.
    • (1997) J Clin Oncol , vol.15 , pp. 1333-1340
    • Swain, S.M.1    Whaley, F.S.2    Gerber, M.C.3    Ewer, M.S.4    Bianchine, J.R.5    Gams, R.A.6
  • 14
    • 10544231456 scopus 로고    scopus 로고
    • Multicenter randomized controlled clinical trial to evaluate cardio-protection of dexrazoxane versus no cardio-protection in women receiving epirubicin chemotherapy for advanced breast cancer
    • Venturini M., Michelotti A., Del Mastro L., Gallo L., Carnino F., Garrone O., et al. Multicenter randomized controlled clinical trial to evaluate cardio-protection of dexrazoxane versus no cardio-protection in women receiving epirubicin chemotherapy for advanced breast cancer. J Clin Oncol 1996, 14:3112-3120.
    • (1996) J Clin Oncol , vol.14 , pp. 3112-3120
    • Venturini, M.1    Michelotti, A.2    Del Mastro, L.3    Gallo, L.4    Carnino, F.5    Garrone, O.6
  • 15
    • 18244363848 scopus 로고    scopus 로고
    • Dexrazoxane for the prevention of cardiomyopathy in anthracycline treated pediatric cancer patients
    • Anderson B. Dexrazoxane for the prevention of cardiomyopathy in anthracycline treated pediatric cancer patients. Pediatr Blood Cancer 2005, 44:584-588.
    • (2005) Pediatr Blood Cancer , vol.44 , pp. 584-588
    • Anderson, B.1
  • 16
    • 9044233260 scopus 로고    scopus 로고
    • Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin
    • Wexler L.H., Andrich M.P., Venzon D., Berg S.L., Weaver-McClure L., Chen C.C., et al. Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin. J Clin Oncol 1996, 14:362-372.
    • (1996) J Clin Oncol , vol.14 , pp. 362-372
    • Wexler, L.H.1    Andrich, M.P.2    Venzon, D.3    Berg, S.L.4    Weaver-McClure, L.5    Chen, C.C.6
  • 17
    • 3042850886 scopus 로고    scopus 로고
    • The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia
    • Lipshultz S.E., Rifai N., Dalton V.M., Levy D.E., Silverman L.B., Lipsitz S.R., et al. The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia. N Engl J Med 2004, 351:145-153.
    • (2004) N Engl J Med , vol.351 , pp. 145-153
    • Lipshultz, S.E.1    Rifai, N.2    Dalton, V.M.3    Levy, D.E.4    Silverman, L.B.5    Lipsitz, S.R.6
  • 19
    • 0032971525 scopus 로고    scopus 로고
    • Quantification of total oxidant scavenging capacity (TOSC) of antioxidants for peroxynitrite, peroxyl radicals and hydroxyl radicals
    • Regoli F., Winston G.W. Quantification of total oxidant scavenging capacity (TOSC) of antioxidants for peroxynitrite, peroxyl radicals and hydroxyl radicals. Toxicol Appl Pharmacol 1999, 156:96-105.
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 96-105
    • Regoli, F.1    Winston, G.W.2
  • 21
    • 0018189958 scopus 로고
    • Overview of cardiac pathology in relation to anthracycline cardiotoxicity
    • Ferrans V.J. Overview of cardiac pathology in relation to anthracycline cardiotoxicity. Cancer Treat Rep 1978, 62:955-961.
    • (1978) Cancer Treat Rep , vol.62 , pp. 955-961
    • Ferrans, V.J.1
  • 22
    • 29244472088 scopus 로고    scopus 로고
    • Effect of epirubicin-based chemotherapy and dexrazoxane supplementation on QT dispersion in non-Hodgkin lymphoma patients
    • Galetta F., Franzoni F., Cervetti G., Cecconi N., Carpi A., Petrini M., et al. Effect of epirubicin-based chemotherapy and dexrazoxane supplementation on QT dispersion in non-Hodgkin lymphoma patients. Biomed Pharmacother 2005, 59:541-544.
    • (2005) Biomed Pharmacother , vol.59 , pp. 541-544
    • Galetta, F.1    Franzoni, F.2    Cervetti, G.3    Cecconi, N.4    Carpi, A.5    Petrini, M.6
  • 23
    • 0027343763 scopus 로고
    • Strategies for prevention of anthracycline cardiotoxicity
    • Basser R.L., Green M.D. Strategies for prevention of anthracycline cardiotoxicity. Cancer Treat Rev 1993, 19:55-77.
    • (1993) Cancer Treat Rev , vol.19 , pp. 55-77
    • Basser, R.L.1    Green, M.D.2
  • 24
    • 0022849760 scopus 로고
    • Differences in O2 reduction by iron complexes of adriamycin and daunorubicin: the importance of sidechain hydroxyl group
    • Zweier J.L., Gianni L., Muindi J., Myers C.E. Differences in O2 reduction by iron complexes of adriamycin and daunorubicin: the importance of sidechain hydroxyl group. Biochem Biophys Acta 1986, 884:326-336.
    • (1986) Biochem Biophys Acta , vol.884 , pp. 326-336
    • Zweier, J.L.1    Gianni, L.2    Muindi, J.3    Myers, C.E.4
  • 25
    • 0024573486 scopus 로고
    • The interaction of the cardioprotective cardioxane (ICRF-197); its hydrolysis product (ICRF-198) and other chelating agents with the Fe (III) and Cu (II) complexes of adriamycin
    • Hasinoff B.B. The interaction of the cardioprotective cardioxane (ICRF-197); its hydrolysis product (ICRF-198) and other chelating agents with the Fe (III) and Cu (II) complexes of adriamycin. Agents Action Suppl 1989, 26:378-385.
    • (1989) Agents Action Suppl , vol.26 , pp. 378-385
    • Hasinoff, B.B.1
  • 26
    • 33645294906 scopus 로고    scopus 로고
    • Multicenter randomized phase III study of the cardioprotective effect of dexrazoxane (Cardioxane) in advanced/metastatic breast cancer patients treated with anthracycline-based chemotherapy
    • Marty M., Espié M., Llombart A., Monnier A., Rapoport B.L., Stahalova V., et al. Multicenter randomized phase III study of the cardioprotective effect of dexrazoxane (Cardioxane) in advanced/metastatic breast cancer patients treated with anthracycline-based chemotherapy. Ann Oncol 2006, 17:614-622.
    • (2006) Ann Oncol , vol.17 , pp. 614-622
    • Marty, M.1    Espié, M.2    Llombart, A.3    Monnier, A.4    Rapoport, B.L.5    Stahalova, V.6
  • 27
    • 0031693006 scopus 로고    scopus 로고
    • Dexrazoxane. A review of its use as a cardioprotective agent in patients receiving anthracycline-based chemotherapy
    • Wiseman L.R., Spencer C.M. Dexrazoxane. A review of its use as a cardioprotective agent in patients receiving anthracycline-based chemotherapy. Drugs 1998, 56:385-403.
    • (1998) Drugs , vol.56 , pp. 385-403
    • Wiseman, L.R.1    Spencer, C.M.2
  • 28
    • 0031906718 scopus 로고    scopus 로고
    • Chemical, biological, and clinical aspects of dexrazoxane and other bisdioxopiperazines
    • Hasinoff B.B., Hellmann K., Hermann E.H., Ferrans V.J. Chemical, biological, and clinical aspects of dexrazoxane and other bisdioxopiperazines. Curr Med Chem 1998, 5:1-28.
    • (1998) Curr Med Chem , vol.5 , pp. 1-28
    • Hasinoff, B.B.1    Hellmann, K.2    Hermann, E.H.3    Ferrans, V.J.4
  • 29
    • 0033040739 scopus 로고    scopus 로고
    • Does vitamin C act as a pro-oxidant under physiological conditions?
    • Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions?. FASEB J 1999, 13:1007-1024.
    • (1999) FASEB J , vol.13 , pp. 1007-1024
    • Carr, A.1    Frei, B.2
  • 30
    • 0033153244 scopus 로고    scopus 로고
    • The ambivalence of vitamin E in atherogenesis
    • Stocker R. The ambivalence of vitamin E in atherogenesis. Trends Biochem Sci 1999, 24:219-223.
    • (1999) Trends Biochem Sci , vol.24 , pp. 219-223
    • Stocker, R.1
  • 31
    • 0031974341 scopus 로고    scopus 로고
    • A rapid gas chromatographic assay for determining oxyradical scavenging capacity of antioxidants and biological fluids
    • Winston G.W., Regoli F., Dugas A.J., Fong J.H., Blanchard K.A. A rapid gas chromatographic assay for determining oxyradical scavenging capacity of antioxidants and biological fluids. Free Radicals Biol Med 1998, 24:480-493.
    • (1998) Free Radicals Biol Med , vol.24 , pp. 480-493
    • Winston, G.W.1    Regoli, F.2    Dugas, A.J.3    Fong, J.H.4    Blanchard, K.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.