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Volumn 11, Issue 10, 2005, Pages 3915-3924

Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin

Author keywords

[No Author keywords available]

Indexed keywords

DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; ICR 187; RAZOXANE;

EID: 18844462177     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-2343     Document Type: Article
Times cited : (42)

References (32)
  • 3
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999;57:727-41.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 4
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004;56:185-229.
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 5
    • 0029944106 scopus 로고    scopus 로고
    • Antitopoisomerase drug action and resistance
    • Nitiss JL, Beck WT. Antitopoisomerase drug action and resistance. Eur J Cancer 1996;32A:958-66.
    • (1996) Eur J Cancer , vol.32 A , pp. 958-966
    • Nitiss, J.L.1    Beck, W.T.2
  • 6
    • 0742269397 scopus 로고    scopus 로고
    • The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: Expert panel review
    • Swain SM, Vici P. The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: expert panel review. J Cancer Res Clin Oncol 2004;130:1-7.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 1-7
    • Swain, S.M.1    Vici, P.2
  • 7
    • 0037096826 scopus 로고    scopus 로고
    • 2002 Update of recommendations for the use of chemotherapy and radiotherapy protectants: Clinical practice guidelines of the American Society of Clinical Oncology
    • Schuchter LM, Hensley ML, Meropol NJ, Winer EP. 2002 update of recommendations for the use of chemotherapy and radiotherapy protectants: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2002;20:2895-903.
    • (2002) J Clin Oncol , vol.20 , pp. 2895-2903
    • Schuchter, L.M.1    Hensley, M.L.2    Meropol, N.J.3    Winer, E.P.4
  • 8
    • 0031906718 scopus 로고    scopus 로고
    • Chemical, biological and clinical aspects of dexrazoxane and other bisdioxopiperazines
    • Hasinoff BB, Hellmann K, Herman EH, Ferrans VJ. Chemical, biological and clinical aspects of dexrazoxane and other bisdioxopiperazines. Curr Med Chem 1998;5:1-28.
    • (1998) Curr Med Chem , vol.5 , pp. 1-28
    • Hasinoff, B.B.1    Hellmann, K.2    Herman, E.H.3    Ferrans, V.J.4
  • 9
    • 0031706330 scopus 로고    scopus 로고
    • Chemistry of dexrazoxane and analogues
    • Hasinoff BB. Chemistry of dexrazoxane and analogues. Semin Oncol 1998;25:3-9.
    • (1998) Semin Oncol , vol.25 , pp. 3-9
    • Hasinoff, B.B.1
  • 10
    • 0027214092 scopus 로고
    • Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5- dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16)
    • Sehested M, Jensen PB, Sorensen BS, Holm B, Friche E, Demant EJ. Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5-dioxopiperazinyl-1- yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16). Biochem Pharmacol 1993;46:389-93.
    • (1993) Biochem Pharmacol , vol.46 , pp. 389-393
    • Sehested, M.1    Jensen, P.B.2    Sorensen, B.S.3    Holm, B.4    Friche, E.5    Demant, E.J.6
  • 11
    • 0030007125 scopus 로고    scopus 로고
    • Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle
    • Sehested M, Jensen PB. Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle. Biochem Pharmacol 1996;51:879-86.
    • (1996) Biochem Pharmacol , vol.51 , pp. 879-886
    • Sehested, M.1    Jensen, P.B.2
  • 12
    • 0141591551 scopus 로고    scopus 로고
    • Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
    • Classen S, Olland S, Berger JM. Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187. Proc Natl Acad Sci U S A 2003;100:10629-34.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10629-10634
    • Classen, S.1    Olland, S.2    Berger, J.M.3
  • 13
    • 0031802032 scopus 로고    scopus 로고
    • Improved targeting of brain tumors using dexrazoxane rescue of topoisomerase II combined with supralethal doses of etoposide and teniposide
    • Holm B, Sehested M, Jensen PB. Improved targeting of brain tumors using dexrazoxane rescue of topoisomerase II combined with supralethal doses of etoposide and teniposide. Clin Cancer Res 1998;4:1367-73.
    • (1998) Clin Cancer Res , vol.4 , pp. 1367-1373
    • Holm, B.1    Sehested, M.2    Jensen, P.B.3
  • 14
    • 0028899095 scopus 로고
    • Etoposide: Twenty years later
    • Hainsworth JD, Greco FA. Etoposide: twenty years later. Ann Oncol 1995;6:325-41.
    • (1995) Ann Oncol , vol.6 , pp. 325-341
    • Hainsworth, J.D.1    Greco, F.A.2
  • 15
    • 18844459059 scopus 로고    scopus 로고
    • Anthracyclines and related compounds
    • DeVita VT, Hellman S, Rosenberg SA, editors. Philadelphia: Lippincott Williams & Wilkins
    • Stewart CF, Ratain MJ. Anthracyclines and related compounds. In: DeVita VT, Hellman S, Rosenberg SA, editors. Cancer; principles and practices of oncology. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2001.
    • (2001) Cancer; Principles and Practices of Oncology. 6th Ed.
    • Stewart, C.F.1    Ratain, M.J.2
  • 16
    • 0021238328 scopus 로고
    • Influence of ICRF-159 or ICRF-186 on cytotoxicity of daunorubicin and doxorubicin
    • Supino R. Influence of ICRF-159 or ICRF-186 on cytotoxicity of daunorubicin and doxorubicin. Tumori 1984;70:121 -6.
    • (1984) Tumori , vol.70 , pp. 121-126
    • Supino, R.1
  • 17
    • 0019499901 scopus 로고
    • Studies in mice treated with ICRF-159 combined with daunorubicin or doxorubicin
    • Giuliani F, Casazza AM, Di Marco A, Savi G. Studies in mice treated with ICRF-159 combined with daunorubicin or doxorubicin. Cancer Treat Rep 1981;65:267-76.
    • (1981) Cancer Treat Rep , vol.65 , pp. 267-276
    • Giuliani, F.1    Casazza, A.M.2    Di Marco, A.3    Savi, G.4
  • 20
    • 0030991044 scopus 로고    scopus 로고
    • Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy
    • Swain SM, Whaley FS, Gerber MC, Ewer MS, Bianchine JR, Gams RA. Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy. J Clin Oncol 1997;15:1333-40.
    • (1997) J Clin Oncol , vol.15 , pp. 1333-1340
    • Swain, S.M.1    Whaley, F.S.2    Gerber, M.C.3    Ewer, M.S.4    Bianchine, J.R.5    Gams, R.A.6
  • 21
    • 0030904096 scopus 로고    scopus 로고
    • Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer
    • Swain SM, Whaley FS, Gerber MC, et al. Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer. J Clin Oncol 1997;15:1318-32.
    • (1997) J Clin Oncol , vol.15 , pp. 1318-1332
    • Swain, S.M.1    Whaley, F.S.2    Gerber, M.C.3
  • 22
    • 0029891617 scopus 로고    scopus 로고
    • ICRF-187 rescue in etoposide treatment in vivo. A model targeting high-dose topoisomerase II poisons to CNS tumors
    • Holm B, Jensen PB, Sehested M. ICRF-187 rescue in etoposide treatment in vivo. A model targeting high-dose topoisomerase II poisons to CNS tumors. Cancer Chemother Pharmacol 1996;38:203-9.
    • (1996) Cancer Chemother Pharmacol , vol.38 , pp. 203-209
    • Holm, B.1    Jensen, P.B.2    Sehested, M.3
  • 23
    • 0344513361 scopus 로고    scopus 로고
    • Dexrazoxane's protection of jejunal crypt cells in the jejunum of C3Hf/Kam mice from doxorubicin-induced toxicity
    • Pearlman M, Jendiroba D, Pagliaro L, et al. Dexrazoxane's protection of jejunal crypt cells in the jejunum of C3Hf/Kam mice from doxorubicin-induced toxicity. Cancer Chemother Pharmacol 2003;52:477-81.
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. 477-481
    • Pearlman, M.1    Jendiroba, D.2    Pagliaro, L.3
  • 24
    • 0035067840 scopus 로고    scopus 로고
    • Dexrazoxane is a potent and specific inhibitor of anthracycline induced subcutaneous lesions in mice
    • Langer SW, Sehested M, Jensen PB. Dexrazoxane is a potent and specific inhibitor of anthracycline induced subcutaneous lesions in mice. Ann Oncol 2001;12:405-10.
    • (2001) Ann Oncol , vol.12 , pp. 405-410
    • Langer, S.W.1    Sehested, M.2    Jensen, P.B.3
  • 25
    • 0030248579 scopus 로고    scopus 로고
    • Impact of scheduling on toxicity and clinical efficacy of doxorubicin: What do we know in the mid-nineties?
    • Bielack SS, Erttmann R, Kempf-Bielack B, Winkler K. Impact of scheduling on toxicity and clinical efficacy of doxorubicin: what do we know in the mid-nineties? Eur J Cancer 1996;32A:1652-60.
    • (1996) Eur J Cancer , vol.32 A , pp. 1652-1660
    • Bielack, S.S.1    Erttmann, R.2    Kempf-Bielack, B.3    Winkler, K.4
  • 26
    • 0026496068 scopus 로고
    • Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin
    • Hochster H, Liebes L, Wadler S, et al. Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin. J Natl Cancer Inst 1992;84:1725-30.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1725-1730
    • Hochster, H.1    Liebes, L.2    Wadler, S.3
  • 27
    • 0023693833 scopus 로고
    • Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer
    • Speyer JL, Green MD, Kramer E, et al. Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer. N Engl J Med 1988;319:745-52.
    • (1988) N Engl J Med , vol.319 , pp. 745-752
    • Speyer, J.L.1    Green, M.D.2    Kramer, E.3
  • 28
    • 0026585672 scopus 로고
    • ICRF-187 permits longer treatment with doxorubicin in women with breast cancer
    • Speyer JL, Green MD, Zeleniuch-Jacquotte A, et al. ICRF-187 permits longer treatment with doxorubicin in women with breast cancer. J Clin Oncol 1992;10:117-27.
    • (1992) J Clin Oncol , vol.10 , pp. 117-127
    • Speyer, J.L.1    Green, M.D.2    Zeleniuch-Jacquotte, A.3
  • 29
    • 0031688723 scopus 로고    scopus 로고
    • Efficacy of dexrazoxane as a cardioprotective agent in patients receiving mitoxantrone- and daunorubicin-based chemotherapy
    • Lemez P, Maresova J. Efficacy of dexrazoxane as a cardioprotective agent in patients receiving mitoxantrone- and daunorubicin-based chemotherapy. Semin Oncol 1998;25:61-5.
    • (1998) Semin Oncol , vol.25 , pp. 61-65
    • Lemez, P.1    Maresova, J.2
  • 30
    • 0025005989 scopus 로고
    • Comparison of the binding of anthracycline derivatives to purified DNA and to cell nuclei
    • Frezard F, Garnier-Suillerot A. Comparison of the binding of anthracycline derivatives to purified DNA and to cell nuclei. Biochim Biophys Acta 1990;1036:121-7.
    • (1990) Biochim Biophys Acta , vol.1036 , pp. 121-127
    • Frezard, F.1    Garnier-Suillerot, A.2
  • 31
    • 0017345240 scopus 로고
    • Transport and binding of daunorubicin, adriamycin, and rubidazone in Ehrlich ascites tumour cells
    • Skovsgaard T. Transport and binding of daunorubicin, adriamycin, and rubidazone in Ehrlich ascites tumour cells. Biochem Pharmacol 1977;26:215-22.
    • (1977) Biochem Pharmacol , vol.26 , pp. 215-222
    • Skovsgaard, T.1
  • 32
    • 0037870269 scopus 로고    scopus 로고
    • Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes
    • Wilstermann AM, Osheroff N. Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes. Curr Top Med Chem 2003;3:321-38.
    • (2003) Curr Top Med Chem , vol.3 , pp. 321-338
    • Wilstermann, A.M.1    Osheroff, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.