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Volumn 84, Issue 3, 1999, Pages 257-265

Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane

Author keywords

Antioxidant; Cardiotoxicity; Dexrazoxane; Superoxide anion

Indexed keywords

DAUNORUBICIN; RAZOXANE;

EID: 0033014821     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.84.3.257     Document Type: Article
Times cited : (193)

References (52)
  • 1
    • 0018650543 scopus 로고
    • Adriamycin cardiotoxicity: A survey of 1273 patients
    • Praga C, Beretta G, Vigo PL. Adriamycin cardiotoxicity: a survey of 1273 patients. Cancer Treat Rep. 1979;63:827-834.
    • (1979) Cancer Treat Rep. , vol.63 , pp. 827-834
    • Praga, C.1    Beretta, G.2    Vigo, P.L.3
  • 6
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: Analysis of prevailing hypotheses
    • Olson RD, Mushlin PS. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J. 1990;4:3076-3086.
    • (1990) FASEB J. , vol.4 , pp. 3076-3086
    • Olson, R.D.1    Mushlin, P.S.2
  • 8
    • 0023028913 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical
    • Doroshow JH, Davies KJA. Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical. J Biol Chem. 1986;261:3068-3074.
    • (1986) J Biol Chem. , vol.261 , pp. 3068-3074
    • Doroshow, J.H.1    Davies, K.J.A.2
  • 9
    • 0029941234 scopus 로고    scopus 로고
    • Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin
    • Dolem LE, Heller LJ, Wallace KB. Dose-dependent increase in sensitivity to calcium-induced mitochondrial dysfunction and cardiomyocyte cell injury by doxorubicin. J Mol Cell Cardiol. 1996;28:1023-1032.
    • (1996) J Mol Cell Cardiol. , vol.28 , pp. 1023-1032
    • Dolem, L.E.1    Heller, L.J.2    Wallace, K.B.3
  • 10
  • 11
    • 0027418306 scopus 로고
    • Antineoplastic agent doxorubicin inhibits myogenic differentiation of C2 myoblasts
    • Kurabayashi M, Jeyaseelan R, Kedes L. Antineoplastic agent doxorubicin inhibits myogenic differentiation of C2 myoblasts. J Biol. 1993;268: 5524-5529.
    • (1993) J Biol. , vol.268 , pp. 5524-5529
    • Kurabayashi, M.1    Jeyaseelan, R.2    Kedes, L.3
  • 12
    • 0028133061 scopus 로고
    • Doxorubicin represses the function of the myogenic helix-loop-helix transcription factor MyoD
    • Kurabayashi M, Jeyaseelan R, Kedes L. Doxorubicin represses the function of the myogenic helix-loop-helix transcription factor MyoD. J Biol Chem. 1994;269:6031-6039.
    • (1994) J Biol Chem. , vol.269 , pp. 6031-6039
    • Kurabayashi, M.1    Jeyaseelan, R.2    Kedes, L.3
  • 13
    • 0028788025 scopus 로고
    • Doxorubicin-induced Id2A gene transcription is targeted at an activating transcription factor/ cyclic AMP response element motif through novel mechanisms involving protein kinases distinct from protein kinase C and protein kinase A
    • Kurabayashi M, Dutta S, Jeyaseelan R, Kedes L. Doxorubicin-induced Id2A gene transcription is targeted at an activating transcription factor/ cyclic AMP response element motif through novel mechanisms involving protein kinases distinct from protein kinase C and protein kinase A. Mol Cell Biol. 1995;15:6386-6397.
    • (1995) Mol Cell Biol. , vol.15 , pp. 6386-6397
    • Kurabayashi, M.1    Dutta, S.2    Jeyaseelan, R.3    Kedes, L.4
  • 14
    • 0018915753 scopus 로고
    • Enzymatic defenses of the mouse heart against reactive oxygen metabolites: Alterations produced by doxorubicin
    • Doroshow JH, Locker GY, Myers CE. Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin. J Clin Invest. 1980;65:128-135.
    • (1980) J Clin Invest. , vol.65 , pp. 128-135
    • Doroshow, J.H.1    Locker, G.Y.2    Myers, C.E.3
  • 15
    • 0019414005 scopus 로고
    • Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine
    • Doroshow JH, Locker GY, Ifrim I, Myers CE. Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine. J Clin Invest. 1981; 68:1053-1064.
    • (1981) J Clin Invest. , vol.68 , pp. 1053-1064
    • Doroshow, J.H.1    Locker, G.Y.2    Ifrim, I.3    Myers, C.E.4
  • 16
    • 0018897888 scopus 로고
    • Failure of the antioxidant vitamin E to protect against Adriamycin-induced cardiotoxicity in the rabbit
    • Breed JG, Zimmerman AN, Dormans JA, Pinedo HM. Failure of the antioxidant vitamin E to protect against Adriamycin-induced cardiotoxicity in the rabbit. Cancer Res. 1980;40:2033-2038.
    • (1980) Cancer Res. , vol.40 , pp. 2033-2038
    • Breed, J.G.1    Zimmerman, A.N.2    Dormans, J.A.3    Pinedo, H.M.4
  • 19
    • 0029148660 scopus 로고
    • Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
    • Bose R, Verheij M, Haimovitz-Friedman A, Scotto K, Fuks Z, Kolesnick R. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell. 1995;82:405-414.
    • (1995) Cell , vol.82 , pp. 405-414
    • Bose, R.1    Verheij, M.2    Haimovitz-Friedman, A.3    Scotto, K.4    Fuks, Z.5    Kolesnick, R.6
  • 20
    • 0027237540 scopus 로고
    • Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumor cells
    • Skladanowski A, Konopa J. Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumor cells. Biochem Pharmacol. 1993;46:375-382.
    • (1993) Biochem Pharmacol. , vol.46 , pp. 375-382
    • Skladanowski, A.1    Konopa, J.2
  • 21
    • 0030008542 scopus 로고    scopus 로고
    • Cytokines and insulin induce cationic amino acid transporter (CAT) expression in cardiac myocytes
    • Simmons WW, Cross EI, Cunningham JM, Smith TW, Kelly RA. Cytokines and insulin induce cationic amino acid transporter (CAT) expression in cardiac myocytes. J Biol Chem. 1996;271:11694-11702.
    • (1996) J Biol Chem. , vol.271 , pp. 11694-11702
    • Simmons, W.W.1    Cross, E.I.2    Cunningham, J.M.3    Smith, T.W.4    Kelly, R.A.5
  • 22
    • 0024580850 scopus 로고
    • Preproenkephalin mRNA expression in developing rat heart and in cultured ventricular cardiac muscle cells
    • Springhorn JP, Claycomb WC. Preproenkephalin mRNA expression in developing rat heart and in cultured ventricular cardiac muscle cells. Biochem J. 1989;258:73-78.
    • (1989) Biochem J. , vol.258 , pp. 73-78
    • Springhorn, J.P.1    Claycomb, W.C.2
  • 23
    • 0025988295 scopus 로고
    • DNA double-strand breaks measured in individual cells subjected to gel electrophoresis
    • Olive PL, Wlodek D, Banath JP. DNA double-strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Res. 1991;51: 4671-4676.
    • (1991) Cancer Res. , vol.51 , pp. 4671-4676
    • Olive, P.L.1    Wlodek, D.2    Banath, J.P.3
  • 24
    • 0025786007 scopus 로고
    • Evaluation of glucocorticoid-induced DNA fragmentation in mouse thymocytes by flow cytometry
    • Telford WG, King LE, Fraher P. Evaluation of glucocorticoid-induced DNA fragmentation in mouse thymocytes by flow cytometry. J Cell Prolif. 1991;24:447-459.
    • (1991) J Cell Prolif. , vol.24 , pp. 447-459
    • Telford, W.G.1    King, L.E.2    Fraher, P.3
  • 25
    • 33750688601 scopus 로고    scopus 로고
    • Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes
    • Sarvazyan N. Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes. Am J Physiol. 1996;271:H2079-H2085.
    • (1996) Am J Physiol. , vol.271
    • Sarvazyan, N.1
  • 26
    • 0023097347 scopus 로고
    • Flow-cytometric characterization of stimulation, free radical formation, peroxidase activity and phagocytosis of human granulocytes with 2,7,-dichlorofluorescein (DCF)
    • Burow S, Valet G. Flow-cytometric characterization of stimulation, free radical formation, peroxidase activity and phagocytosis of human granulocytes with 2,7,-dichlorofluorescein (DCF). Eur J Cell Biol. 1987;43: 128-133.
    • (1987) Eur J Cell Biol. , vol.43 , pp. 128-133
    • Burow, S.1    Valet, G.2
  • 27
    • 0028108976 scopus 로고
    • Oxidation pathways for the intracellular probe 2′,7′-dichlorofluorescein
    • Zhu H, Bannerberg G, Modeus P, Shertzer H. Oxidation pathways for the intracellular probe 2′,7′-dichlorofluorescein. Arch Toxicol. 1994;68: 582-587.
    • (1994) Arch Toxicol. , vol.68 , pp. 582-587
    • Zhu, H.1    Bannerberg, G.2    Modeus, P.3    Shertzer, H.4
  • 28
    • 0029918858 scopus 로고    scopus 로고
    • Functional significance of the Cu,ZnSOD in Escherichia coli.
    • Benov L, Fridovich I. Functional significance of the Cu,ZnSOD in Escherichia coli. Arch Biochem Biophys. 1996;327:249-253.
    • (1996) Arch Biochem Biophys. , vol.327 , pp. 249-253
    • Benov, L.1    Fridovich, I.2
  • 29
    • 0027989826 scopus 로고
    • Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo
    • Faulkner KM, Kiochev SI, Fridovich I. Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J Biol Chem. 1994;269:23471-23476.
    • (1994) J Biol Chem. , vol.269 , pp. 23471-23476
    • Faulkner, K.M.1    Kiochev, S.I.2    Fridovich, I.3
  • 31
    • 0019207710 scopus 로고
    • A stereological analysis of the effect of Adriamycin on the ultrastructure of rat myocardial cells in culture
    • Tobin TP, Abbott BC. A stereological analysis of the effect of Adriamycin on the ultrastructure of rat myocardial cells in culture. J Mol Cell Cardiol. 1980;12:1207-1225.
    • (1980) J Mol Cell Cardiol. , vol.12 , pp. 1207-1225
    • Tobin, T.P.1    Abbott, B.C.2
  • 32
    • 0018933538 scopus 로고
    • Structural and functional effects of Adriamycin on cardiac cells in vitro
    • Lampidis TJ, Henderson IC, Israel M, Canellos GP. Structural and functional effects of Adriamycin on cardiac cells in vitro. Cancer Res. 1980; 40:3901-3909.
    • (1980) Cancer Res. , vol.40 , pp. 3901-3909
    • Lampidis, T.J.1    Henderson, I.C.2    Israel, M.3    Canellos, G.P.4
  • 33
    • 0019417972 scopus 로고
    • Amelioration of adriamycin and daunorubicin myocardial toxicity by adenosine
    • Newman RA, Hacker MP, Krakoff IH. Amelioration of Adriamycin and daunorubicin myocardial toxicity by adenosine. Cancer Res. 1981;41: 3483-3488.
    • (1981) Cancer Res. , vol.41 , pp. 3483-3488
    • Newman, R.A.1    Hacker, M.P.2    Krakoff, I.H.3
  • 34
    • 0026006327 scopus 로고
    • L-type cardiac calcium channels in doxorubicin cardiomyopathy in rats: Morphological, biochemical, and functional correlations
    • Keung EC, Toll L, Ellis M, Jensen RA. L-type cardiac calcium channels in doxorubicin cardiomyopathy in rats: morphological, biochemical, and functional correlations. J Clin Invest. 1991;87:2108-2113.
    • (1991) J Clin Invest. , vol.87 , pp. 2108-2113
    • Keung, E.C.1    Toll, L.2    Ellis, M.3    Jensen, R.A.4
  • 35
    • 0028788025 scopus 로고
    • Doxorubicin-induced Id2A gene transcription is targeted at an activating transcription factor/ cyclic AMP response element motif through novel mechanisms involving protein kinases distinct from protein kinase C and protein kinase A
    • Kurabayashi M, Dutta S, Jeyaseelan R, Kedes L. Doxorubicin-induced Id2A gene transcription is targeted at an activating transcription factor/ cyclic AMP response element motif through novel mechanisms involving protein kinases distinct from protein kinase C and protein kinase A. Mol Cell Biol. 1995;15:6386-6397.
    • (1995) Mol Cell Biol. , vol.15 , pp. 6386-6397
    • Kurabayashi, M.1    Dutta, S.2    Jeyaseelan, R.3    Kedes, L.4
  • 37
    • 0031047983 scopus 로고    scopus 로고
    • Molecular mechanisms of doxorubicin-induced cardiomyopathy: Selective suppression of Reishe iron-sulfur protein, ADT/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes
    • Jeyaseelan R, Poizat C, Wu H-Y, Kedes L. Molecular mechanisms of doxorubicin-induced cardiomyopathy: selective suppression of Reishe iron-sulfur protein, ADT/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes. J Biol Chem. 1997;272:5828-5832.
    • (1997) J Biol Chem. , vol.272 , pp. 5828-5832
    • Jeyaseelan, R.1    Poizat, C.2    Wu, H.-Y.3    Kedes, L.4
  • 38
    • 0030248675 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis in spontaneously hypertensive rats: Differential effects in heart, kidney and intestine, and inhibition by ICRF-187
    • Zhang J, Clark JR Jr, Herman EH, Ferrans VJ. Doxorubicin-induced apoptosis in spontaneously hypertensive rats: differential effects in heart, kidney and intestine, and inhibition by ICRF-187. J Mol Cell Cardiol. 1996;28:1931-1943.
    • (1996) J Mol Cell Cardiol. , vol.28 , pp. 1931-1943
    • Zhang, J.1    Clark J., Jr.2    Herman, E.H.3    Ferrans, V.J.4
  • 40
    • 0028100951 scopus 로고
    • Early detection of anthracycline cardiotoxicity in children with acme leukemia using exercise-based echocardiography and Doppler echocardiography
    • Fukazawa R, Ogawa S, Hirayama T. Early detection of anthracycline cardiotoxicity in children with acme leukemia using exercise-based echocardiography and Doppler echocardiography. Jpn Circ J. 1994;58: 625-634.
    • (1994) Jpn Circ J. , vol.58 , pp. 625-634
    • Fukazawa, R.1    Ogawa, S.2    Hirayama, T.3
  • 41
    • 0000305836 scopus 로고    scopus 로고
    • Increased circulating levels of cardiac troponin I in anthracycline-treated patients
    • Abstract
    • Missor E, Pau B, Calzolari C. Increased circulating levels of cardiac troponin I in anthracycline-treated patients. Circulation. 1996;94(suppl I):I-732. Abstract.
    • (1996) Circulation , vol.94 , Issue.1 SUPPL.
    • Missor, E.1    Pau, B.2    Calzolari, C.3
  • 42
    • 0019307472 scopus 로고
    • Spin-trapping and direct electron spin resonance investigations of the redox metabolism of the redox metabolism of quinone anticancer drugs
    • Kalyanaraman B, Perez-Reyes E, Mason RP. Spin-trapping and direct electron spin resonance investigations of the redox metabolism of the redox metabolism of quinone anticancer drugs. Biochim Biophys Acta. 1988;630:119-130.
    • (1988) Biochim Biophys Acta , vol.630 , pp. 119-130
    • Kalyanaraman, B.1    Perez-Reyes, E.2    Mason, R.P.3
  • 43
    • 0022967083 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase
    • Davies KJA, Doroshow J. Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. J Biol Chem. 1986;261:3060-3067.
    • (1986) J Biol Chem. , vol.261 , pp. 3060-3067
    • Davies, K.J.A.1    Doroshow, J.2
  • 44
    • 0017595763 scopus 로고
    • Adriamycin stimulated superoxide formation in submitochondrial particles
    • Thayer WS. Adriamycin stimulated superoxide formation in submitochondrial particles. Chem Biol Interact. 1977;19:265-278.
    • (1977) Chem Biol Interact. , vol.19 , pp. 265-278
    • Thayer, W.S.1
  • 45
    • 0020961074 scopus 로고
    • 2; an explanation for the cardiotoxicity of anthracycline antibiotics
    • 2; an explanation for the cardiotoxicity of anthracycline antibiotics. Biochem Biophys Res Commun. 1983;114:197-205.
    • (1983) Biochem Biophys Res Commun. , vol.114 , pp. 197-205
    • Nohl, H.1    Jordan, W.2
  • 46
    • 0023726412 scopus 로고
    • Adriamycin-induced free radical formation in the perfused rat heart: Implications for cardiotoxicity
    • Rajagopalan S, Politi PM, Sinha BK, Myers CE. Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity. Cancer Res. 1988;48:4766-4769.
    • (1988) Cancer Res. , vol.48 , pp. 4766-4769
    • Rajagopalan, S.1    Politi, P.M.2    Sinha, B.K.3    Myers, C.E.4
  • 47
    • 0027740137 scopus 로고
    • The one-ring open hydrolysis product intermediates of the cardioprotective agent CRF-187 (dexrazoxane) displace iron from iron anthracycline complexes
    • Buss JL, Hasinoff BB. The one-ring open hydrolysis product intermediates of the cardioprotective agent CRF-187 (dexrazoxane) displace iron from iron anthracycline complexes. Agents Actions. 1993;40:86-95.
    • (1993) Agents Actions , vol.40 , pp. 86-95
    • Buss, J.L.1    Hasinoff, B.B.2
  • 49
    • 0027517512 scopus 로고
    • Inhibition by sulfhydryl compounds of vascular relaxation induced by nitric oxide and endothelium-derived relaxing factor
    • Jia L, Furchgott F. Inhibition by sulfhydryl compounds of vascular relaxation induced by nitric oxide and endothelium-derived relaxing factor. J Pharmacol Exp Ther. 1993;267:371-378.
    • (1993) J Pharmacol Exp Ther. , vol.267 , pp. 371-378
    • Jia, L.1    Furchgott, F.2
  • 51
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells
    • Schreck R, Meier B, Mannel DN, Droge W, Baeuerle PA. Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J Exp Med. 1992;175:1181-1194.
    • (1992) J Exp Med. , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Mannel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 52
    • 0029781555 scopus 로고    scopus 로고
    • The protective role of manganese superoxide dismutase against Adriamycin-induced acute cardiac toxicity in transgenic mice
    • Yen HC, Oberley TD, Vichitbandha S, Ho YS, St Clair DK. The protective role of manganese superoxide dismutase against Adriamycin-induced acute cardiac toxicity in transgenic mice. J Clin Invest. 1996;98:1253-1260.
    • (1996) J Clin Invest. , vol.98 , pp. 1253-1260
    • Yen, H.C.1    Oberley, T.D.2    Vichitbandha, S.3    Ho, Y.S.4    St Clair, D.K.5


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