-
2
-
-
0028226564
-
Etoposide (VP-16): Cytogenetic studies in mice
-
K Agarwal A Mukherjee S Sen 1994 Etoposide (VP-16): cytogenetic studies in mice Environ Mol Mutagen 23 3 190 193
-
(1994)
Environ Mol Mutagen
, vol.23
, Issue.3
, pp. 190-193
-
-
Agarwal, K.1
Mukherjee, A.2
Sen, S.3
-
3
-
-
0032189962
-
Catalytic inhibitors of DNA topoisomerase II
-
T Andoh R Ishida 1998 Catalytic inhibitors of DNA topoisomerase II Biochim Biophys Acta 1400 155 171
-
(1998)
Biochim Biophys Acta
, vol.1400
, pp. 155-171
-
-
Andoh, T.1
Ishida, R.2
-
4
-
-
0028068277
-
Potent clastogenicity of the human carcinogen etoposide to the mouse bone marrow and mouse lymphoma L5178Y cells: Comparison to Salmonella responses
-
J Ashby H Tinwell P Glover 1994 Potent clastogenicity of the human carcinogen etoposide to the mouse bone marrow and mouse lymphoma L5178Y cells: comparison to Salmonella responses Environ Mol Mutagen 24 51 60
-
(1994)
Environ Mol Mutagen
, vol.24
, pp. 51-60
-
-
Ashby, J.1
Tinwell, H.2
Glover, P.3
-
5
-
-
55349087274
-
Abatement by naringin of lomefloxacin-induced genomic instability in mice
-
SM Attia 2008 Abatement by naringin of lomefloxacin-induced genomic instability in mice Mutagenesis 23 6 515 521
-
(2008)
Mutagenesis
, vol.23
, Issue.6
, pp. 515-521
-
-
Attia, S.M.1
-
6
-
-
0037225813
-
Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe
-
SM Attia U Kliesch G Schriever-Schwemmer 2003 Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe Environ Mol Mutagen 41 99 103
-
(2003)
Environ Mol Mutagen
, vol.41
, pp. 99-103
-
-
Attia, S.M.1
Kliesch, U.2
Schriever-Schwemmer, G.3
-
7
-
-
0037179507
-
Molecular cytogenetic analysis in mouse sperm of chemically induced aneuploidy: Studies with topoisomerase II inhibitors
-
SM Attia TE Schmid OA Badary 2002 Molecular cytogenetic analysis in mouse sperm of chemically induced aneuploidy: studies with topoisomerase II inhibitors Mutat Res 520 1 13
-
(2002)
Mutat Res
, vol.520
, pp. 1-13
-
-
Attia, S.M.1
Schmid, T.E.2
Badary, O.A.3
-
8
-
-
0033922361
-
Genotoxicity of several clinically used topoisomerase II inhibitors
-
G Boos H Stopper 2000 Genotoxicity of several clinically used topoisomerase II inhibitors Toxicol Lett 116 1-2 7 16
-
(2000)
Toxicol Lett
, vol.116
, Issue.12
, pp. 7-16
-
-
Boos, G.1
Stopper, H.2
-
9
-
-
0028933380
-
Differences in inhibition of chromosome separation and G2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26
-
M Chen WT Beck 1995 Differences in inhibition of chromosome separation and G2 arrest by DNA topoisomerase II inhibitors merbarone and VM-26 Cancer Res 55 1509 1516
-
(1995)
Cancer Res
, vol.55
, pp. 1509-1516
-
-
Chen, M.1
Beck, W.T.2
-
10
-
-
1842666763
-
Cytogenetic risk assessment of etoposide from mouse bone marrow
-
RC Choudhury AK Palo PJ Sahu 2004 Cytogenetic risk assessment of etoposide from mouse bone marrow Appl Toxicol 24 115 122
-
(2004)
Appl Toxicol
, vol.24
, pp. 115-122
-
-
Choudhury, R.C.1
Palo, A.K.2
Sahu, P.J.3
-
11
-
-
14744279771
-
Modulatory effect of quercetin on DNA damage, induced by etoposide in bone marrow cells and on changes in the activity of antioxidant enzymes in rats
-
A Cierniak M Papiez M Kapiszewska 2004 Modulatory effect of quercetin on DNA damage, induced by etoposide in bone marrow cells and on changes in the activity of antioxidant enzymes in rats Rocz Akad Med Bialymst 49 Suppl. 1 167 169
-
(2004)
Rocz Akad Med Bialymst
, vol.49
, Issue.SUPPL. 1
, pp. 167-169
-
-
Cierniak, A.1
Papiez, M.2
Kapiszewska, M.3
-
12
-
-
0024329909
-
In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone
-
FH Drake GA Hofmann SM Mong 1989 In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone Cancer Res 49 10 2578 2583
-
(1989)
Cancer Res
, vol.49
, Issue.10
, pp. 2578-2583
-
-
Drake, F.H.1
Hofmann, G.A.2
Mong, S.M.3
-
13
-
-
0001448027
-
Tissue sulfhydryl groups
-
GL Ellman 1959 Tissue sulfhydryl groups Arch Biochem Biophys 74 214 226
-
(1959)
Arch Biochem Biophys
, vol.74
, pp. 214-226
-
-
Ellman, G.L.1
-
14
-
-
0035056832
-
Leukemias related to treatment with DNA topoisomerase II inhibitors
-
CA Felix 2001 Leukemias related to treatment with DNA topoisomerase II inhibitors Med Pediatr Oncol 36 5 525 535
-
(2001)
Med Pediatr Oncol
, vol.36
, Issue.5
, pp. 525-535
-
-
Felix, C.A.1
-
15
-
-
0032168167
-
Etoposide: Four decades of development of a topoisomerase II inhibitor
-
KR Hande 1998 Etoposide: four decades of development of a topoisomerase II inhibitor Eur J Cancer 34 10 1514 1521
-
(1998)
Eur J Cancer
, vol.34
, Issue.10
, pp. 1514-1521
-
-
Hande, K.R.1
-
16
-
-
0028810791
-
A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane)
-
BB Hasinoff TI Kuschak JC Yalowich 1995 A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane) Biochem Pharmacol 50 953 958
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 953-958
-
-
Hasinoff, B.B.1
Kuschak, T.I.2
Yalowich, J.C.3
-
17
-
-
0029796045
-
The effect of dexrazoxane (ICRF-187) on doxorubicin- and daunorubicin mediated growth inhibition of Chinese hamster ovary cells
-
BB Hasinoff JC Yalowich Y Ling 1996 The effect of dexrazoxane (ICRF-187) on doxorubicin- and daunorubicin mediated growth inhibition of Chinese hamster ovary cells Anticancer Drugs 7 558 567
-
(1996)
Anticancer Drugs
, vol.7
, pp. 558-567
-
-
Hasinoff, B.B.1
Yalowich, J.C.2
Ling, Y.3
-
18
-
-
25144508808
-
Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors
-
KF Hofland AV Thougaard M Dejligbjerg 2005 Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors Clin Cancer Res 11 18 6722 6729
-
(2005)
Clin Cancer Res
, vol.11
, Issue.18
, pp. 6722-6729
-
-
Hofland, K.F.1
Thougaard, A.V.2
Dejligbjerg, M.3
-
19
-
-
18844462177
-
Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin
-
KF Hofland V Thougaard M Sehested 2005 Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin Cancer Res 11 3915 3924
-
(2005)
Cancer Res
, vol.11
, pp. 3915-3924
-
-
Hofland, K.F.1
Thougaard, V.2
Sehested, M.3
-
20
-
-
0029891617
-
ICRF-187 rescue in etoposid treatment in vivo. A model targeting high dose topoisomerase II poisons to CNS tumors
-
B Holm PB Jensen M Sehested 1996 ICRF-187 rescue in etoposid treatment in vivo. A model targeting high dose topoisomerase II poisons to CNS tumors Cancer Chemother Pharmacol 38 203 209
-
(1996)
Cancer Chemother Pharmacol
, vol.38
, pp. 203-209
-
-
Holm, B.1
Jensen, P.B.2
Sehested, M.3
-
21
-
-
0141958578
-
Cytotoxicity and cell cycle effects of novel indolo[2, 3-b]quinoline derivatives
-
R Humeniuk L Kaczmarek W Peczynska-Czoch 2003 Cytotoxicity and cell cycle effects of novel indolo[2, 3-b]quinoline derivatives Oncol Res 13 5 269 277
-
(2003)
Oncol Res
, vol.13
, Issue.5
, pp. 269-277
-
-
Humeniuk, R.1
Kaczmarek, L.2
Peczynska-Czoch, W.3
-
22
-
-
0035502997
-
Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: Role of myeloperoxidase
-
VE Kagan AI Kuzmenko YY Tyurina 2001 Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase Cancer Res 61 7777 7784
-
(2001)
Cancer Res
, vol.61
, pp. 7777-7784
-
-
Kagan, V.E.1
Kuzmenko, A.I.2
Tyurina, Y.Y.3
-
23
-
-
0032868183
-
Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: Free radical/antioxidant approach
-
VE Kagan JC Yalowich GG Borisenko 1999 Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach Mol Pharmacol 56 494 506
-
(1999)
Mol Pharmacol
, vol.56
, pp. 494-506
-
-
Kagan, V.E.1
Yalowich, J.C.2
Borisenko, G.G.3
-
24
-
-
33845197460
-
Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin
-
H Kaiserová GJ den Hartog T Simůnek 2006 Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin Br J Pharmacol 149 7 920 930
-
(2006)
Br J Pharmacol
, vol.149
, Issue.7
, pp. 920-930
-
-
Kaiserová, H.1
Den Hartog, G.J.2
Simůnek, T.3
-
25
-
-
34547824188
-
Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin
-
M Kapiszewska A Cierniak M Elas 2007 Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin Toxicol In Vitro 21 6 1020 1030
-
(2007)
Toxicol in Vitro
, vol.21
, Issue.6
, pp. 1020-1030
-
-
Kapiszewska, M.1
Cierniak, A.2
Elas, M.3
-
26
-
-
33847047843
-
Prolonged quercetin administration diminishes the etopoide-induced DAN damage in bone marrow cells of rats
-
M Kapiszewska A Cierniak MA Papiez 2007 Prolonged quercetin administration diminishes the etopoide-induced DAN damage in bone marrow cells of rats Drug Chem Toxicol 30 67 81
-
(2007)
Drug Chem Toxicol
, vol.30
, pp. 67-81
-
-
Kapiszewska, M.1
Cierniak, A.2
Papiez, M.A.3
-
27
-
-
0035067840
-
Dexrazoxane is a potent and specific inhibitor of anthracycline induced subcutaneous lesions in mice
-
SW Langer M Sehested PB Jensen 2001 Dexrazoxane is a potent and specific inhibitor of anthracycline induced subcutaneous lesions in mice Ann Oncol 12 405 410
-
(2001)
Ann Oncol
, vol.12
, pp. 405-410
-
-
Langer, S.W.1
Sehested, M.2
Jensen, P.B.3
-
28
-
-
34447573788
-
Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats
-
D Lebrecht A Geist UP Ketelsen 2007 Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats Br J Pharmacol 151 6 771 778
-
(2007)
Br J Pharmacol
, vol.151
, Issue.6
, pp. 771-778
-
-
Lebrecht, D.1
Geist, A.2
Ketelsen, U.P.3
-
30
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
G Minotti P Menna E Salvatorelli 2004 Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity Pharmacol Rev 56 185 229
-
(2004)
Pharmacol Rev
, vol.56
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
-
31
-
-
0033054992
-
DNA damage signals induction of Fas ligand in tumor cells
-
YY Mo WT Beck 1999 DNA damage signals induction of Fas ligand in tumor cells Mol Pharmacol 55 216 222
-
(1999)
Mol Pharmacol
, vol.55
, pp. 216-222
-
-
Mo, Y.Y.1
Beck, W.T.2
-
32
-
-
0018384650
-
Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction
-
H Ohkawa N Ohishi K Yagi 1979 Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 95 351 358
-
(1979)
Anal Biochem
, vol.95
, pp. 351-358
-
-
Ohkawa, H.1
Ohishi, N.2
Yagi, K.3
-
33
-
-
0037411223
-
Dexrazoxane in combination with anthracyclines lead to a synergistic cytotoxic response in acute myelogenous leukemia cell lines
-
M Pearlman D Jendiroba L Pagliaro 2003 Dexrazoxane in combination with anthracyclines lead to a synergistic cytotoxic response in acute myelogenous leukemia cell lines Leuk Res 27 617 626
-
(2003)
Leuk Res
, vol.27
, pp. 617-626
-
-
Pearlman, M.1
Jendiroba, D.2
Pagliaro, L.3
-
34
-
-
0344513361
-
Dexrazoxane's protection of jejunal crypt cells in the jejunum of C3Hf/Kam mice from doxorubicin-induced toxicity
-
M Pearlman D Jendiroba L Pagliaro 2003 Dexrazoxane's protection of jejunal crypt cells in the jejunum of C3Hf/Kam mice from doxorubicin-induced toxicity Cancer Chemother Pharmacol 52 477 481
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 477-481
-
-
Pearlman, M.1
Jendiroba, D.2
Pagliaro, L.3
-
35
-
-
0029089072
-
Antioxidant paradoxes of phenolic compounds: Peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical
-
VB Ritov R Goldman DA Stoyanovsky 1995 Antioxidant paradoxes of phenolic compounds: peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical Arch Biochem Biophys 321 140 152
-
(1995)
Arch Biochem Biophys
, vol.321
, pp. 140-152
-
-
Ritov, V.B.1
Goldman, R.2
Stoyanovsky, D.A.3
-
36
-
-
0027214092
-
Antagonistic effect of the cardioprotector (+)-1, 2-bis(3, 5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16)
-
M Sehested PB Jensen BS Sørensen 1993 Antagonistic effect of the cardioprotector (+)-1, 2-bis(3, 5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16) Biochem Pharmacol 46 3 389 393
-
(1993)
Biochem Pharmacol
, vol.46
, Issue.3
, pp. 389-393
-
-
Sehested, M.1
Jensen, P.B.2
Sørensen, B.S.3
-
37
-
-
0032764065
-
Protection of acute myeloblastic leukemia cells against apoptotic cell death by high glutathione and gamma-glutamylcysteine synthetase levels during etoposide-induced oxidative stress
-
T Siitonen P Alaruikka P Mantymaa 1999 Protection of acute myeloblastic leukemia cells against apoptotic cell death by high glutathione and gamma-glutamylcysteine synthetase levels during etoposide-induced oxidative stress Ann Oncol 10 1361 1367
-
(1999)
Ann Oncol
, vol.10
, pp. 1361-1367
-
-
Siitonen, T.1
Alaruikka, P.2
Mantymaa, P.3
-
38
-
-
0028110492
-
Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells
-
PJ Smith S Soués T Gottlieb 1994 Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells Br J Cancer 70 914 921
-
(1994)
Br J Cancer
, vol.70
, pp. 914-921
-
-
Smith, P.J.1
Soués, S.2
Gottlieb, T.3
-
39
-
-
0742269397
-
The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: Expert panel review
-
SM Swain P Vici 2004 The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: expert panel review J Cancer Res Clin Oncol 130 1 7
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 1-7
-
-
Swain, S.M.1
Vici, P.2
-
40
-
-
0030991044
-
Delayed administration of dexrazoxane provides cordiaprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy
-
SM Swain F Whaley MC Gerber 1997 Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy J Clin Oncol 15 1333 1340 (Pubitemid 27167364)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.4
, pp. 1333-1340
-
-
Swain, S.M.1
Whaley, F.S.2
Gerber, M.C.3
Ewer, M.S.4
Bianchine, J.R.5
Gams, R.A.6
-
41
-
-
0035724690
-
DNA topoisomerases as targets for anticancer drugs
-
Z Topcu 2001 DNA topoisomerases as targets for anticancer drugs J Clin Pharm Ther 26 405 416
-
(2001)
J Clin Pharm Ther
, vol.26
, pp. 405-416
-
-
Topcu, Z.1
-
42
-
-
0035958287
-
Assays to predict the genotoxicity of the chromosomal mutagen etoposide-focussing on the best assay
-
SD Turner SW Wijnhoven H Tinwell 2001 Assays to predict the genotoxicity of the chromosomal mutagen etoposide-focussing on the best assay Mutat Res 493 1-2 139 147
-
(2001)
Mutat Res
, vol.493
, Issue.12
, pp. 139-147
-
-
Turner, S.D.1
Wijnhoven, S.W.2
Tinwell, H.3
-
43
-
-
0030014783
-
DNA topoisomerases
-
JC Wang 1996 DNA topoisomerases Annu Rev Biochem 65 635 692
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 635-692
-
-
Wang, J.C.1
-
44
-
-
0036304758
-
Catalytic inhibitors of topoisomerase II are DNA-damaging agents: Induction of chromosomal damage by merbarone and ICRF-187
-
L Wang DA Eastmond 2002 Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187 Environ Mol Mutagen 39 4 348 356
-
(2002)
Environ Mol Mutagen
, vol.39
, Issue.4
, pp. 348-356
-
-
Wang, L.1
Eastmond, D.A.2
-
45
-
-
0031818870
-
ICRF-187 (dexrazoxan) protects from adriamycin-induced nephrotic syndrome in rats
-
T Zima V Tesar J Crkovská 1998 ICRF-187 (dexrazoxan) protects from adriamycin-induced nephrotic syndrome in rats Nephrol Dial Transplant 13 8 1975 1979
-
(1998)
Nephrol Dial Transplant
, vol.13
, Issue.8
, pp. 1975-1979
-
-
Zima, T.1
Tesar, V.2
Crkovská, J.3
|