-
1
-
-
2342577439
-
Irbesartan: A reviewof its use in hypertension and in the management of diabeticnephropathy
-
Croom KF, Curran MP, Goa KL, Perry CM. Irbesartan: a reviewof its use in hypertension and in the management of diabeticnephropathy. Drugs 2004; 64: 999-1028.
-
(2004)
Drugs
, vol.64
, pp. 999-1028
-
-
Croom, K.F.1
Curran, M.P.2
Goa, K.L.3
Perry, C.M.4
-
2
-
-
68149098704
-
Thevalue of irbesartan in the management of hypertension
-
Bramlage P, Durand-Zaleski I, Desai N, Pirk N, Hacker C. Thevalue of irbesartan in the management of hypertension. ExpertOpin Pharmacother 2009; 10: 1817-31.
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 1817-1831
-
-
Bramlage, P.1
Durand-Zaleski, I.2
Desai, N.3
Pirk, N.4
Hacker, C.5
-
3
-
-
0028321529
-
Differentialexpression and activation of a family of murine peroxisome proliferator-activated receptors
-
USA
-
Kliewer SA, Forman BM, Blumberg B, et al. Differentialexpression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA 1994; 91: 7355-59.
-
(1994)
Proc Natl Acad Sci
, vol.91
, pp. 7355-7359
-
-
Kliewer, S.A.1
Forman, B.M.2
Blumberg, B.3
-
4
-
-
5444264003
-
Biological control through regulatedtranscription coactivators
-
Spiegelman BM, Heinrich R. Biological control through regulatedtranscription coactivators. Cell 2004; 119: 157-67.
-
(2004)
Cell
, vol.119
, pp. 157-167
-
-
Spiegelman, B.M.1
Heinrich, R.2
-
5
-
-
2442451618
-
Angiotensintype 1 receptor blockers induce peroxisome proliferator-activatedreceptor-γ activity
-
Schupp M, Janke J, Clasen R, Unger T, Kintscher U. Angiotensintype 1 receptor blockers induce peroxisome proliferator-activatedreceptor-γ activity. Circulation 2004; 109: 2054-7.
-
(2004)
Circulation
, vol.109
, pp. 2054-2057
-
-
Schupp, M.1
Janke, J.2
Clasen, R.3
Unger, T.4
Kintscher, U.5
-
6
-
-
33644672013
-
Molecular characterizationof new selective peroxisome proliferator-activated receptor γ modulators with angiotensin receptor blocking activity
-
Schupp M, Clemenz M, Gineste R, et al. Molecular characterizationof new selective peroxisome proliferator-activated receptor γ modulators with angiotensin receptor blocking activity. Diabetes 2005; 54: 3442-52.
-
(2005)
Diabetes
, vol.54
, pp. 3442-3452
-
-
Schupp, M.1
Clemenz, M.2
Gineste, R.3
-
7
-
-
41149167048
-
Should we use PPAR agonists to reduce cardiovascularrisk?
-
Article ID 891425
-
Robinson JG. Should we use PPAR agonists to reduce cardiovascularrisk? PPAR Research 2008; 2008: Article ID 891425, 1-13.
-
(2008)
PPAR Research
, vol.2008
, pp. 1-13
-
-
Robinson, J.G.1
-
8
-
-
45349084588
-
PPAR γ Agonists: Potential astherapeutics for neovascular retinopathies
-
Article ID 164273
-
Pershadsingh HA, Moore DM. PPAR γ Agonists: potential astherapeutics for neovascular retinopathies. PPAR Res 2008; 2008: Article ID 164273, 1-13.
-
(2008)
PPAR Res
, vol.2008
, pp. 1-13
-
-
Pershadsingh, H.A.1
Moore, D.M.2
-
9
-
-
1542547460
-
Identification oftelmisartan as a unique angiotensin II receptor antagonist withselective PPAR γ-modulating activity
-
Benson SC, Pershadsingh HA, Ho CI, et al. Identification oftelmisartan as a unique angiotensin II receptor antagonist withselective PPAR γ-modulating activity. Hypertension 2004; 43: 993-1002.
-
(2004)
Hypertension
, vol.43
, pp. 993-1002
-
-
Benson, S.C.1
Pershadsingh, H.A.2
Ho, C.I.3
-
10
-
-
62749114341
-
Characterization of new PPARγ agonists: Analysis of telmisartan'sstructural components
-
Goebel M, Clemenz M, Staels B, Unger T, Kintscher U, Gust R. Characterization of new PPARγ agonists: analysis of telmisartan'sstructural components. ChemMedChem 2009; 4: 445-6.
-
(2009)
Chem Med Chem
, vol.4
, pp. 445-446
-
-
Goebel, M.1
Clemenz, M.2
Staels, B.3
Unger, T.4
Kintscher, U.5
Gust, R.6
-
11
-
-
34447128782
-
Insights into the mechanismof partial agonism: Crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complexwith two enantiomeric ligands
-
Pochetti G, Godio C, Mitro N, et al. Insights into the mechanismof partial agonism: crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complexwith two enantiomeric ligands. J Biol Chem 2007; 282: 17314-24.
-
(2007)
J Biol Chem
, vol.282
, pp. 17314-17324
-
-
Pochetti, G.1
Godio, C.2
Mitro, N.3
-
12
-
-
33746330410
-
Insulin resistance, hyperinsulinemia,and renal injury: Mechanisms and implications
-
Sarafidis PA, Ruilope LM. Insulin resistance, hyperinsulinemia,and renal injury: mechanisms and implications. Am J Nephrol 2006; 26: 232-44.
-
(2006)
Am J Nephrol
, vol.26
, pp. 232-244
-
-
Sarafidis, P.A.1
Ruilope, L.M.2
-
13
-
-
34748828509
-
Obesity and obesity-initiated metabolicsyndrome: Mechanistic links to chronic kidney disease
-
Wahba IM, Mak RH. Obesity and obesity-initiated metabolicsyndrome: mechanistic links to chronic kidney disease. Clin J AmSoc Nephrol 2007; 2: 550-62.
-
(2007)
Clin J Am Soc Nephrol
, vol.2
, pp. 550-562
-
-
Wahba, I.M.1
Mak, R.H.2
-
14
-
-
36248983781
-
Thiazolidinediones: A novel class of drugs forthe prevention of diabetic nephropathy?
-
Zheng F, Guan Y. Thiazolidinediones: a novel class of drugs forthe prevention of diabetic nephropathy? Kidney Int 2007, 72: 1301-3.
-
(2007)
Kidney Int
, vol.72
, pp. 1301-1303
-
-
Zheng, F.1
Guan, Y.2
-
16
-
-
1542498518
-
Peroxisome proliferator-activated receptorgamma: Therapeutic target for disease beyond diabetes: Quo vadis?
-
Pershadsingh HA. Peroxisome proliferator-activated receptorgamma: therapeutic target for disease beyond diabetes: quo vadis? Expert Opinion Investigational Drugs 2004; 13: 215-28.
-
(2004)
Expert Opinion Investigational Drugs
, vol.13
, pp. 215-228
-
-
Pershadsingh, H.A.1
-
17
-
-
1642446053
-
Peroxisome proliferator-activatedreceptor-γ: Too much of a good thing causes harm
-
Cock TA, Houten SM, Auwerx J. Peroxisome proliferator-activatedreceptor-γ: too much of a good thing causes harm. EMBO Rep 2004; 5: 142-7.
-
(2004)
EMBO Rep
, vol.5
, pp. 142-147
-
-
Cock, T.A.1
Houten, S.M.2
Auwerx, J.3
-
19
-
-
38549101139
-
Beneficial effectsof pioglitazone on hypertensive cardiovascular injury are enhancedby combination with candesartan
-
Nakamura T, Yamamoto E, Kataoka K, et al. Beneficial effectsof pioglitazone on hypertensive cardiovascular injury are enhancedby combination with candesartan. Hypertension 2008; 51: 296-301.
-
(2008)
Hypertension
, vol.51
, pp. 296-301
-
-
Nakamura, T.1
Yamamoto, E.2
Kataoka, K.3
-
20
-
-
44649160542
-
Pioglitazone enhances theantihypertensive and renoprotective effects of candesartan inZucker obese rats fed a high-protein diet
-
Namikoshi T, Tomita N, Satoh M, et al. Pioglitazone enhances theantihypertensive and renoprotective effects of candesartan inZucker obese rats fed a high-protein diet. Hypertens Res 2008; 31: 745-55.
-
(2008)
Hypertens Res
, vol.31
, pp. 745-755
-
-
Namikoshi, T.1
Tomita, N.2
Satoh, M.3
-
21
-
-
34447530707
-
Renoprotection provided by losartan in combinationwith pioglitazene is superior to renoprotection provided bylosartan alone in patients with type 2 diabetic nephropathy
-
Jin HM, Pan Y. Renoprotection provided by losartan in combinationwith pioglitazene is superior to renoprotection provided bylosartan alone in patients with type 2 diabetic nephropathy. KidneyBlood Press Res 2007; 30: 203-11.
-
(2007)
Kidney Blood Press Res
, vol.30
, pp. 203-211
-
-
Jin, H.M.1
Pan, Y.2
-
22
-
-
70349297078
-
The protectiveeffect of irbesartan in rats fed a high fat diet is associated withmodification of leptin-adiponectin imbalance
-
de las Heras N, Martin-Fernandez B, Miana M, et al. The protectiveeffect of irbesartan in rats fed a high fat diet is associated withmodification of leptin-adiponectin imbalance. J Hypertens 2009; 27(suppl 6): S37-S41.
-
(2009)
J Hypertens
, vol.27
, Issue.SUPPL 6
-
-
de las Heras, N.1
Martin-Fernandez, B.2
Miana, M.3
-
23
-
-
34247342132
-
Irbesartanfor the treatment of hypertension in patients with the metabolicsyndrome: A sub analysis of the treat to target post authorizationsurvey. Prospective observational, two armed study in 14,200patients
-
Kintscher U, Bramlage P, Paar WD, Thoenes M, Unger T. Irbesartanfor the treatment of hypertension in patients with the metabolicsyndrome: a sub analysis of the treat to target post authorizationsurvey. Prospective observational, two armed study in 14,200patients. Cardiovasc Diabetol 2007; 6: 12.
-
(2007)
Cardiovasc Diabetol
, vol.6
, pp. 12
-
-
Kintscher, U.1
Bramlage, P.2
Paar, W.D.3
Thoenes, M.4
Unger, T.5
-
24
-
-
38549128802
-
Effect of the angiotensinreceptor blocker irbesartan on metabolic parameters in clinicalpractice: The DO-IT prospective observational study
-
Parhofer KG, Münzel F, Krekler M. Effect of the angiotensinreceptor blocker irbesartan on metabolic parameters in clinicalpractice: the DO-IT prospective observational study. CardiovascDiabetol 2007; 6: 36.
-
(2007)
Cardiovasc Diabetol
, vol.6
, pp. 36
-
-
Parhofer, K.G.1
Münzel, F.2
Krekler, M.3
-
25
-
-
33748316445
-
The role ofrenin-angiotensin-aldosterone system in the progression of chronickidney disease
-
Remuzzi G, Perico N, Macia M, Ruggenenti P. The role ofrenin-angiotensin-aldosterone system in the progression of chronickidney disease. Kidney Int 2005; 68(suppl 99): S57-S65.
-
(2005)
Kidney Int
, vol.68
, Issue.SUPPL 99
-
-
Remuzzi, G.1
Perico, N.2
Macia, M.3
Ruggenenti, P.4
-
26
-
-
17444427737
-
The pathophysiologic basis for blocking the reninangiotensinsystem in hypertensive patients with renal disease
-
Raij L. The pathophysiologic basis for blocking the reninangiotensinsystem in hypertensive patients with renal disease. AmJ Hypertens 2005; 18: 95S-9S.
-
(2005)
Am J Hypertens
, vol.18
-
-
Raij, L.1
-
27
-
-
0037409237
-
The adipose-tissue reninangiotensin-aldosterone system: Role in the metabolic syndrome?
-
Engeli S, Scling P, Gorzelniak K, et al. The adipose-tissue reninangiotensin-aldosterone system: role in the metabolic syndrome? Int J Biochem Cell Biol 2003; 35: 807-25.
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 807-825
-
-
Engeli, S.1
Scling, P.2
Gorzelniak, K.3
-
28
-
-
77958049298
-
-
Pharmaceuticaland Medical Devices Agency
-
Information on New Drug Application, Irbesartan. Pharmaceuticaland Medical Devices Agency 2008; (http://www.info.pmda.go.jp/shinyaku/g080407/index.html).
-
(2008)
Information on New Drug Application, Irbesartan
-
-
-
29
-
-
10844278000
-
Metabolic fate of losartan,a new angiotensin II receptor antagonist (1): Absorption, distribution,metabolism and excretion after single administration in rats
-
Takayama F, Saito K, Yoshinaga T, et al. Metabolic fate of losartan,a new angiotensin II receptor antagonist (1): absorption, distribution,metabolism and excretion after single administration in rats. Xenohio Metabol Dispos 1995; 10: 223-43.
-
(1995)
Xenohio Metabol Dispos
, vol.10
, pp. 223-243
-
-
Takayama, F.1
Saito, K.2
Yoshinaga, T.3
-
30
-
-
77958064757
-
-
Pharmaceuticaland Medical Devices Agency
-
Information on New Drug Application, Telmisartan. Pharmaceuticaland Medical Devices Agency 2002; (http://www.info.pmda.go.jp/shinyaku/g021008/index.html?submit=%C9%BD%BC%A8).
-
(2002)
Information on New Drug Application, Telmisartan
-
-
-
31
-
-
77958071662
-
-
Japan Pharmacists Education Center
-
Information on New Drug Application, Valsartan. Japan PharmacistsEducation Center 2000; (http://www.jpec.or.jp/contents/c01/link.html).
-
(2000)
Information on New Drug Application, Valsartan
-
-
-
32
-
-
0029894243
-
Disposition of the newangiotensin II receptor antagonist candesartan cilexetil in rats anddog
-
Kondo T, Yoshida K, Yoshimura Y, et al. Disposition of the newangiotensin II receptor antagonist candesartan cilexetil in rats anddog. Arzneim-Forsch/Drug Res 1996; 46: 594-600.
-
(1996)
Arzneim-Forsch/Drug Res
, vol.46
, pp. 594-600
-
-
Kondo, T.1
Yoshida, K.2
Yoshimura, Y.3
-
33
-
-
77958073143
-
-
Pharmaceuticaland Medical Devices Agency
-
Information on New Drug Application, Olmesartan. Pharmaceuticaland Medical Devices Agency 2004; (http://www.info.pmda.go.jp/shinyaku/g040105/index.html?submit=%C9%BD%BC%A8).
-
(2004)
Information on New Drug Application, Olmesartan
-
-
-
34
-
-
0035922447
-
Renoprotectiveeffect of the angiotensin-receptor antagonist irbesartan in patientswith nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotectiveeffect of the angiotensin-receptor antagonist irbesartan in patientswith nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-60.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
35
-
-
0035922444
-
The effect ofirbesartan on the development of diabetic nephropathy in patientswith type 2 diabetes
-
Parving HH, Lehnert H, Bröchner-Mortensen J, et al. The effect ofirbesartan on the development of diabetic nephropathy in patientswith type 2 diabetes. N Engl J Med 2001; 345: 870-8.
-
(2001)
N Engl J Med
, vol.345
, pp. 870-878
-
-
Parving, H.H.1
Lehnert, H.2
Bröchner-Mortensen, J.3
-
36
-
-
0037118662
-
Use of irbesartan tomaintain sinus rhythm in patients with long-lasting persistent atrialfibrillation: A prospective and randomized study
-
Madrid AH, Bueno MG, Rebollo JMG, et al. Use of irbesartan tomaintain sinus rhythm in patients with long-lasting persistent atrialfibrillation: a prospective and randomized study. Circulation 2002; 106: 331-6.
-
(2002)
Circulation
, vol.106
, pp. 331-336
-
-
Madrid, A.H.1
Bueno, M.G.2
Rebollo, J.M.G.3
-
37
-
-
77951061989
-
A randomized evaluation of irbesartan versus placeboin patients with atrial fibrillation (factorial design of ACTIVEprogram)
-
Yusuf S. A randomized evaluation of irbesartan versus placeboin patients with atrial fibrillation (factorial design of ACTIVEprogram). European Society of Cardiology 2009; (http://www.escardio.org/congresses/esc-2009/congress-reports/Pages/708005-708006-yusuf-brugada.aspx).
-
(2009)
European Society of Cardiology
-
-
Yusuf, S.1
|