Acrylamide genotoxicity in young versus adult gpt delta male rats

Mutagenesis

Volumn 26, Issue 4, 2011, Pages 545-549

  Koyama, Naoki ^a,b,c   Yasui, Manabu ^a   Kimura, Aoi ^a,d   Takami, Shigeaki ^a,e   Suzuki, Takuya ^f   Masumura, Kenichi ^a   Nohmi, Takehiko ^a   Masuda, Shuichi ^b   Kinae, Naohide ^b   Matsuda, Tomonari ^f   Imai, Toshio ^a,g   Honma, Masamitsu ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c EISAI CO LTD   (Japan)

^d SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^e Biosafety Research Center   (Japan)

^f KYOTO UNIVERSITY   (Japan)

^g NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE; CARCINOGEN; DRINKING WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; COMET ASSAY; CONTROLLED STUDY; DNA ADDUCT; FISCHER 344 RAT; GENOTOXICITY; GROUPS BY AGE; LIVER EXAMINATION; MALE; MAMMARY GLAND; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; TESTIS; TRANSGENICS; UNITED KINGDOM;

ACRYLAMIDE; AGING; ANIMALS; BODY WEIGHT; BONE MARROW; COMET ASSAY; DNA ADDUCTS; FEMALE; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENS; MUTATION; ORGAN SPECIFICITY; RATS; RATS, TRANSGENIC;

ANIMALIA; RATTUS; SOLANUM TUBEROSUM;

EID: 79959716447     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ger014     Document Type: Article

References (45)

1. Bergmark, E. (1997) Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers. Chem. Res. Toxicol., 10, 78-84.
2. Tareke, E., Rydberg, P., Karlsson, P., Eriksson, S. and Tornqvist, M. (2002) Analysis of acrylamide, a carcinogen formed in heated foodstuffs. J. Agric. Food Chem., 50, 4998-5006.
3. Tareke, E., Rydberg, P., Karlsson, P., Eriksson, S. and Tornqvist, M. (2000) Acrylamide: a cooking carcinogen? Chem. Res. Toxicol., 13, 517-522.
4. Mottram, D. S., Wedzicha, B. L. and Dodson, A. T. (2002) Acrylamide is formed in the Maillard reaction. Nature, 419, 448-449.
5. Stadler, R. H., Blank, I., Varga, N., Robert, F., Hau, J., Guy, P. A., Robert, M. C. and Riediker, S. (2002) Acrylamide from Maillard reaction products. Nature, 419, 449-450.
6. Rice, J. M. (2005) The carcinogenicity of acrylamide. Mutat. Res., 580, 3-20.
7. Tyl, R. W., Marr, M. C., Myers, C. B., Ross, W. P. and Friedman, M. A. (2000) Relationship between acrylamide reproductive and neurotoxicity in male rats. Reprod. Toxicol., 14, 147-157.
8. Yang, H. J., Lee, S. H., Jin, Y., Choi, J. H., Han, C. H. and Lee, M. H. (2005) Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats. J. Vet. Sci., 6, 103-109.
9. LoPachin, R. M., Balaban, C. D. and Ross, J. F. (2003) Acrylamide axonopathy revisited. Toxicol. Appl. Pharmacol., 188, 135-153.
10. Carere, A. (2006) Genotoxicity and carcinogenicity of acrylamide: a critical review. Ann. Ist. Super. Sanita, 42, 144-155.
11. Besaratinia, A. and Pfeifer, G. P. (2007) A review of mechanisms of acrylamide carcinogenicity. Carcinogenesis, 28, 519-528. (Pubitemid 46523347)
12. IARC (1994) Acrylamide. In: IARC Monographs on the Evaluation of Carcinogen Risk to Human: Some Industrial Chemicals. International Agency for Research on Cancer Lyon, France, 60, pp. 389-433.
13. Abramsson-Zetterberg, L. (2003) The dose-response relationship at very low doses of acrylamide is linear in the flow cytometer-based mouse micronucleus assay. Mutat. Res., 535, 215-222.
14. Manjanatha, M. G., Aidoo, A., Shelton, S. D., Bishop, M. E., MacDaniel, L. P., Lyn-Cock, L. E. and Doerge, D. R. (2006) Genotoxicity of acrylamide and its metabolite glycidamide administrated in drinking water to male and female Big Blue mice. Environ. Mol. Mutagen., 47, 6-17.
15. Dearfield, K. L., Douglas, G. R., Ehling, U. H., Moore, M. M., Sega, G. A. and Brusick, D. J. (1995) Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk. Mutat. Res., 330, 71-99.
16. Dearfield, K. L., Abernathy, C. O., Ottley, M. S., Brantner, J. H. and Hayes, P. F. (1988) Acrylamide: its metabolism, developmental and reproductive effects, genotoxicity, and carcinogenicity. Mutat. Res., 195, 45-77.
17. Koyama, N., Sakamoto, H., Sakuraba, M. et al. (2006) Genotoxicity of acrylamide and glycidamide in human lymphoblastoid TK6 cells. Mutat. Res., 603, 151-158.
18. Koyama, N., Yasui, M., Oda, Y. et al. (2011) Genotoxicity of acrylamide in vitro: acrylamide is not metabolically activated in standard in vitro systems. Environ. Mol. Mutagen., 52, 12-19.
19. Sumner, S. C., Fennell, T. R., Moore, T. A., Chanas, B., Gonzalez, F. and Ghanayem, B. I. (1999) Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice. Chem. Res. Toxicol., 12, 1110-1116.
20. Ghanayem, B. I., McDaniel, L. P., Churchwell, M. I., Twaddle, N. C., Snyder, R., Fennell, T. R. and Doerge, D. R. (2005) Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts. Toxicol. Sci., 88, 311-318.
21. Doerge, D. R., Young, J. F., McDaniel, L. P., Twaddle, N. C. and Churchwell, M. I. (2005) Toxicokinetics of acrylamide and glycidamide in B6C3F1 mice. Toxicol. Appl. Pharmacol., 202, 258-267.
22. Gamboa, d. C., Churchwell, M. I., Hamilton, L. P., Von Tungeln, L. S., Beland, F. A., Marques, M. M. and Doerge, D. R. (2003) DNA adduct formation from acrylamide via conversion to glycidamide in adult and neonatal mice. Chem. Res. Toxicol., 16, 1328-1337.
23. Segerback, D., Calleman, C. J., Schroeder, J. L., Costa, L. G. and Faustman, E. M. (1995) Formation of N-7-(2-carbamoyl-2- hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide. Carcinogenesis, 16, 1161-1165.
24. Neafsey, P., Ginsberg, G., Hattis, D., Johns, D. O., Guyton, K. Z. and Sonawane, B. (2009) Genetic polymorphism in CYP2E1: population distribution of CYP2E1 activity. J. Toxicol. Environ. Health B Crit. Rev., 12, 362-388.
25. Mucci, L. A. and Wilson, K. M. (2008) Acrylamide intake through diet and human cancer risk. J. Agric. Food Chem., 56, 6013-6019.
26. Spivey, A. (2010) A matter of degrees: advancing our understanding of acrylamide. Environ. Health Perspect., 118, A160-A167.
27. Hayashi, M., Sofuni, T. and Morita, T. (1991) Simulation study of the effects of multiple treatments in the mouse bone marrow micronucleus test. Mutat. Res., 252, 281-287.
28. Tice, R. R., Agurell, E., Anderson, D. et al. (2000) Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen., 35, 206-221.
29. Burlinson, B., Tice, R. R., Speit, G. et al. (2007) Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup. Mutat. Res., 627, 31-35.
30. Kimura, A., Torigoe, N., Miyata, A. and Honma, M. (2010) Validation of a simple in vitro comet assay method using CHL cells. Genes Environ., 32, 61-65.
31. Nohmi, T., Suzuki, T. and Masumura, K. (2000) Recent advances in the protocols of transgenic mouse mutation assays. Mutat. Res., 455, 191-215.
32. Cao, J., Beisker, W., Nusse, M. and Adler, I. D. (1993) Flow cytometric detection of micronuclei induced by chemicals in poly- and normochromatic erythrocytes of mouse peripheral blood. Mutagenesis, 8, 533-541.
33. Ghanayem, B. I., Witt, K. L., Kissling, G. E., Tice, R. R. and Recio, L. (2005) Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect. Mutat. Res., 578, 284-297.
34. Mei, N., McDaniel, L. P., Dobrovolsky, V. N. et al. (2010) The genotoxicity of acrylamide and glycidamide in big blue rats. Toxicol. Sci., 115, 412-421.
35. Takahashi, M., Shibutani, M., Inoue, K., Fujimoto, H., Hirose, M. and Nishikawa, A. (2008) Pathological assessment of the nervous and male reproductive systems of rat offspring exposed maternally to acrylamide during the gestation and lactation periods - a preliminary study. J. Toxicol. Sci., 33, 11-24.
36. Xiao, Y. and Tates, A. D. (1994) Increased frequencies of micronuclei in early spermatids of rats following exposure of young primary spermatocytes to acrylamide. Mutat. Res., 309, 245-253.
37. Lahdetie, J., Suutari, A. and Sjoblom, T. (1994) The spermatid micronucleus test with the dissection technique detects the germ cell mutagenicity of acrylamide in rat meiotic cells. Mutat. Res., 309, 255-262.
38. Shelby, M. D., Cain, K. T., Cornett, C. V. and Generoso, W. M. (1987) Acrylamide: induction of heritable translocation in male mice. Environ. Mutagen., 9, 363-368.
39. Adler, I. D., Reitmeir, P., Schmoller, R. and Schriever-Schwemmer, G. (1994) Dose response for heritable translocations induced by acrylamide in spermatids of mice. Mutat. Res., 309, 285-291.
40. Wu, Y. Q., Yu, A. R., Tang, X. Y., Zhang, J. and Cui, T. (1993) Determination of acrylamide metabolite, mercapturic acid by high performance liquid chromatography. Biomed. Environ. Sci., 6, 273-280.
41. Calleman, C. J., Bergmark, E. and Costa, L. G. (1990) Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation. Chem. Res. Toxicol., 3, 406-412.
42. Jiang, Y., Kuo, C. L., Pernecky, S. J. and Piper, W. N. (1998) The detection of cytochrome P450 2E1 and its catalytic activity in rat testis. Biochem. Biophys. Res. Commun., 246, 578-583.
43. Wang, R. S., McDaniel, L. P., Manjanatha, M. G., Shelton, S. D., Doerge, D. R. and Mei, N. (2010) Mutagenicity of acrylamide and glycidamide in the testes of big blue mice. Toxicol. Sci., 117, 72-80.
44. Takahashi, M., Inoue, K., Koyama, N., Yoshida, M., Irie, K., Morikawa, T., Shibutani, M., Honma, M. and Nishikawa, A. (2011) Life stage-related differences in susceptibility to acrylamide-induced neural and testicular toxicity. Arch Toxicol, (Epub ahead of print).
45. Chen, T., Heflich, R. H., Moore, M. M. and Mei, N. (2010) Differential mutagenicity of aflatoxin B1 in the liver of neonatal and adult mice. Environ. Mol. Mutagen., 51, 156-163.