Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds

Biomaterials

Volumn 32, Issue 2, 2011, Pages 419-429

  Hafeman, Andrea E ^a,b   Zienkiewicz, Katarzyna J ^a,b   Zachman, Angela L ^a   Sung, Hak Joon ^a   Nanney, Lillian B ^c   Davidson, Jeffrey M ^c,d   Guelcher, Scott A ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Biodegradation; Hydrolysis; Macrophage; Oxidation; Polyurethane; Scaffold

Indexed keywords

BREAKDOWN PRODUCTS; CONTROLLED DEGRADATION; CYTOTOXIC; DEGRADATION MECHANISM; DEGRADATION RATE; DELIVERY SYSTEMS; DOMINANT MECHANISM; ESTER BONDS; HEXAMETHYLENE DIISOCYANATE; HISTOLOGICAL SECTION; HYDROXY ACIDS; IN-VITRO; IN-VIVO; INFLAMMATORY RESPONSE; MATERIAL SURFACE; MYELOPEROXIDASE; OXIDATIVE DEGRADATION; OXIDATIVE MECHANISM; PERFORMANCE CRITERION; PHYSIOLOGICAL PROCESS; POLY(ESTER URETHANE); POLYESTERURETHANES; POLYISOCYANATES; POLYMERIC SCAFFOLD; PRECLINICAL STUDIES; REGENERATIVE MEDICINE; TISSUE REGENERATION;

ACIDS; AMINO ACIDS; BIODEGRADATION; CARBOXYLIC ACIDS; DEGRADATION; ESTERIFICATION; ESTERS; HYDROLYSIS; MACROPHAGES; MICROBIOLOGY; ORGANIC POLYMERS; OXIDATION; PHYSIOLOGICAL MODELS; TISSUE;

SCAFFOLDS;

ALIPHATIC COMPOUND; ESTER DERIVATIVE; HEXAMETHYLENE DIISOCYANATE; HYDROXYACID; ISOCYANIC ACID DERIVATIVE; LYSINE DERIVATIVE; MOLECULAR SCAFFOLD; MYELOPEROXIDASE; POLYESTER; REACTIVE OXYGEN METABOLITE; URETHAN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIODEGRADATION; CONTROLLED STUDY; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TISSUE REGENERATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; LYSINE; MALE; MATERIALS TESTING; MECHANICS; MICE; MICROSCOPY, ELECTRON, SCANNING; POLYESTERS; POLYURETHANES; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; TISSUE SCAFFOLDS; WOUND HEALING;

RATTUS;

EID: 78449239908     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.108     Document Type: Article

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