Intracellular Ca2+ signaling and store-operated Ca2+ entry are required in Drosophila neurons for flight

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 25, 2009, Pages 10326-10331

  Venkiteswaran, Gayatri ^a   Hasan, Gaiti ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Calcium homeostasis; Flight patterns; Inositol 1,4,5 trisphosphate receptor; Sarco endoplasmic reticulum associated Ca2+ ATPase; STIM

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CELL PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PROTEIN ORAI; PROTEIN STIM; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SMALL INTERFERING RNA; STORE OPERATED CALCIUM CHANNEL; UNCLASSIFIED DRUG; CALCIUM; CALMODULIN ACCEPTOR PROTEIN 60; CALMODULIN BINDING PROTEIN; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; ORAI1 PROTEIN, DROSOPHILA; STIM1 PROTEIN, DROSOPHILA;

ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; DROSOPHILA; DROSOPHILA MELANOGASTER; ENDOPLASMIC RETICULUM; FLYING; GENOTYPE; MOTONEURON; NERVE CELL; NERVE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; ALLELE; ANIMAL; GENETICS; METABOLISM; PHYSIOLOGY;

DROSOPHILA MELANOGASTER;

ALLELES; ANIMALS; CALCIUM; CALCIUM SIGNALING; CALMODULIN-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FLIGHT, ANIMAL; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MEMBRANE PROTEINS; NEURONS; RNA, SMALL INTERFERING;

EID: 67649852511     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902982106     Document Type: Article

References (33)

1. Berridge MJ (1998) Neuronal calcium signaling. Neuron 21:13-26.
2. Borodinsky LN, Spitzer NC (2007) Activity-dependent neurotransmitter- receptor matching at the neuromuscular junction. Proc Natl Acad Sci USA 104:335-340. (Pubitemid 46068032)
3. Feske S, et al. (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441:179-185.
4. 2+ entry. Science 312:1220-1223.
5. Zhang SL, et al. (2006) Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Proc Natl Acad Sci USA 103:9357-9362. (Pubitemid 43902581)
6. Prakriya M, et al. (2006) Orai1 is an essential pore subunit of the CRAC channel. Nature 443:230-233. (Pubitemid 44387613)
7. Vig M, et al. (2006) CRACM1 multimers form the ion-selective pore of the CRAC channel. Curr Biol 16:2073-2079. (Pubitemid 44573821)
8. Yeromin AV, et al. (2006) Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 443:226-229. (Pubitemid 44387612)
9. 2+ influx. Curr Biol 15:1235-1241.
10. 2+ store to the plasma membrane. Nature 437:902-905.
11. Yuan JP, et al. (2009) SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol 11:337-343.
12. Banerjee S, Lee J, Venkatesh K, Wu CF, Hasan G (2004) Loss of flight and associated neuronal rhythmicity in inositol 1,4,5-trisphosphate receptor mutants of Drosophila. J Neurosci 24:7869-7878. (Pubitemid 39215691)
13. Banerjee S, Hasan G (2005) The InsP3 receptor: Its role in neuronal physiology and neurodegeneration. BioEssays 27:1035-1047. (Pubitemid 41608960)
14. Matsumoto M, et al. (1996) Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature 379:168-171. (Pubitemid 26020199)
15. Inoue T, Kato K, Kohda K, Mikoshiba K (1998) Type 1 inositol 1,4,5-trisphosphate receptor is required for induction of long-term depression in cerebellar Purkinje neurons. J Neurosci 18:5366-5373. (Pubitemid 28311953)
16. Feske S, Giltnane J, Dolmetsch R, Staudt LM, Rao A (2001) Gene regulation mediated by calcium signals in T lymphocytes. Nat Immunol 2:316-324. (Pubitemid 33706342)
17. Brandman O, Liou J, Park WS, Meyer T (2007) STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 131:1327-1339. (Pubitemid 350297421)
18. Benzer S (1973) Genetic dissection of behavior. Sci Am 229(6):24-37.
19. Joshi R, Venkatesh K, Srinivas R, Nair S, Hasan G (2004) Genetic dissection of itpr gene function reveals a vital requirement in aminergic cells of Drosophila larvae. Genetics 166:225-236. (Pubitemid 38364716)
20. Bellen HJ, et al. (2004) The BDGP gene disruption project: Single transposon insertions associated with 40% of Drosophila genes. Genetics 167:761-781. (Pubitemid 38931863)
21. Sanyal S, et al. (2005) Analysis of conditional paralytic mutants in Drosophila sarcoendoplasmic reticulum calcium ATPase reveals novel mechanisms for regulating membrane excitability. Genetics 169:737-750. (Pubitemid 40404307)
22. Banerjee S, et al. (2006) Compensation of inositol 1,4,5-trisphosphate receptor function by altering sarco-endoplasmic reticulum calcium ATPase activity in the Drosophila flight circuit. J Neurosci 26:8278-8288. (Pubitemid 44309841)
23. Millar NS, et al. (1995) Functional expression of a cloned Drosophila muscarinic acetylcholine receptor in a stable Drosophila cell line. J Exp Biol 198:1843-1850.
24. Frye MA, Dickinson MH (2004) Closing the loop between neurobiology and flight behavior in Drosophila. Curr Opin Neurobiol 14:729-736. (Pubitemid 39576205)
25. Srikanth S, et al. (2004) Functional properties of the Drosophila melanogaster inositol 1,4,5-trisphosphate receptor mutants. Biophys J 86:3634-3646. (Pubitemid 38780242)
26. 2+ entry: A STIMulating st Orai. Trends Biochem Sci 31:597-601.
27. 2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets. Biochim Biophys Acta 1783:1163-1176.
28. van de Leemput J, et al. (2007) Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS Genet 3:e108. (Pubitemid 47015866)
29. 2+ pump, cause Darier disease. Nat Genet 21:271-277.
30. Mahr A, Aberle H (2006) The expression pattern of the Drosophila vesicular glutamate transporter: A marker protein for motoneurons and glutamatergic centers in the brain. Gene Expr Patterns 6:299-309. (Pubitemid 43257218)
31. Lundell MJ, Hirsh J (1994) Temporal and spatial development of serotonin and dopamine neurons in the Drosophila CNS. Dev Biol 165:385-396. (Pubitemid 24359804)
32. Rulifson EJ, Kim SK, Nusse R (2002) Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes. Science 296:1118-1120. (Pubitemid 34517128)
33. Wu CF, Suzuki N, Poo MM (1983) Dissociated neurons from normal and mutant Drosophila larval central nervous system in cell culture. J Neurosci 3:1888-1899.