Reduction of infarct volume by halothane: Effect on cerebral blood flow or perifocal spreading depression-like depolarizations

Journal of Cerebral Blood Flow and Metabolism

Volumn 17, Issue 8, 1997, Pages 857-864

  Saito, Ryoichi ^a   Graf, Rudolf ^a   Hübel, Kai ^a   Fujita, Toshiaki ^a   Rosner, Gerd ^a   Heiss, Wolf Dieter ^a  

^a MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

Author keywords

Brain protection; Focal cerebral ischemia; Halothane; Regional CBF; SD like depolarizations

Indexed keywords

HALOTHANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN PROTECTION; CAT; DEPOLARIZATION; DRUG EFFECT; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030848038     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199708000-00004     Document Type: Article

References (44)

1. Back T, Kohno K, Hossmann KA (1994) Cortical negative DC deflections following middle cerebral artery occlusion and KCl-induced spreading depression: effect on blood flow, tissue oxygenation, and electroencephalogram. J Cereb Blood Flow Metab 14: 12-19
2. Chen Q, Chopp M, Bodzin G, Chen H (1993) Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: correlation with ischemic injury. J Cereb Blood Flow Metab 13: 389-394
3. Dermietzel R, Spray DC (1993) Gap junctions in the brain: where, what type, how many and why? Trends Neurosci 16:186-192
4. Gorelova NA, Koroleva VI, Amemori T, Pavlik V, Bures J (1987) Ketamine blockade of cortical spreading depression in rats. EEG Clin Neurophysiol 66:440-447
5. Graf R, Kataoka K, Rosner G, Heiss W-D (1986) Cortical deafferentation in cat focal ischemia: disturbance and recovery of sensory functions in cortical areas with different degrees of CBF reduction. J Cereb Blood Flow Metab 6:566-573
6. Graf R, Saito K, Hübel T, Fujita T, Rosner G, Heiss W-D (1995) Spreading depression-like DC-negativations turn into terminal depolarization after prolonged focal ischemia in cats. J Cereb Blood Flow Metab (Suppl 1)15:S15
7. Grafstein B (1956) Mechanism of spreading cortical depression. J Neurophysiol 19:154-171
8. Hansen AJ, Quistorff B, Gjedde A (1980) Relationship between local changes in cortical blood flow and extracellular K+ during spreading depression. Acta Physiol Scand 109:1-6
9. Heiss W-D, Graf R, Wienhard K, Löttgen J, Saito R, Fujita T, Rosner G, Wagner R (1994) Dynamic penumbra demonstrated by sequential multitracer PET after middle cerebral artery occlusion in cats. J Cereb Blood Flow Metab 14:892-902
10. Helfaer MA, Kirsch JR, Traystman RJ (1990) Anesthetic modulation of cerebral hemodynamic and evoked responses to transient middle cerebral artery occlusion in cats. Stroke 21:795-800
11. Herbert DA, Mitchell RA (1971) Blood gas tensions and acidic balance in awake cats. J Appl Physiol 30:434-436
12. Higashida H, Mitarai G, Watanabe S (1974) A comparative study of membrane potential changes in neurons and neuroglial cells during spreading depression in the rabbit. Brain Res 65:411-425
13. Hossmann KA (1994) Glutamate-mediated injury in focal cerebral ischemia: the excitotoxin hypothesis revised. Brain Pathology 4: 23-36
14. Iijima T, Mies G, Hossmann KA (1992) Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury. J Cereb Blood Flow Metab 12:727-733
15. Kohno KT, Hoehn-Berlage M, Mies G, Back T, Hossmann KA (1995) Relationship between diffusion-weighted magnetic resonance images, cerebral blood flow and energy state in experimental brain infarction. Magn Reson Imaging 13:73-80
16. Leão AAP (1944) Spreading depression of activity in the cerebral cortex. J Neurophysiol 7:359-390
17. MacVicar BA, Dudek FE (1980) Dye-coupling between CA3 pyramidal cells in slices of rat hippocampus. Brain Res 196:494-497
18. Mantz J, Cordier J, Giaume C (1993) Effects of general anesthetics on intercellular communications mediated by gap junctions between astrocytes in primary culture. Anesthesiology 78:892-901
19. Michenfelder J, Milde J (1975) Influence of anesthetics on metabolic, functional, and pathological responses to regional cerebral ischemia. Stroke 6:405-410
20. Mies G, Iijima T, Hossmann KA (1993) Correlation between peri-infarct DC shifts and ischaemic neuronal damage in rat. NeuroReport 4:709-711
21. Nedergaard M (1994) Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science 263:1768-1771
22. Nedergaard M, Astrup J (1986) Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation. J Cereb Blood Flow Metab. 6:607-615
23. Nedergaard M, Cooper AJ, Goldman SA (1995) Gap junctions are required for the propagation of spreading depression. J Neurobiol 28:433-444
24. Nedergaard M, Hansen AJ (1993) Characterization of cortical depolarizations evoked in focal cerebral ischemia. J Cereb Blood Flow Metab 13:568-574
25. Nedergaard M, Hansen AJ (1988) Spreading depression is not associated with neuronal injury in the normal brain. Brain Res 449:395-398
26. Patel PM, Drummond JC, Cole DJ, Goskowicz RL (1995) Isoflurane reduces ischemia-induced glutamate release in rats subjected to forebrain ischemia. Anesthesiology 82:996-1003
27. Piper RD, Lambert GA (1996) Inhalational anesthetics inhibit spreading depression: relevance to migraine. Cephalalgia 16:87-92
28. Reinoso-Suárez F (1961) Topographischer Hirnatlas der Katze, E. Merck AG, Darmstadt, Germany
29. Saito R, Graf R, Hübel K, Taguchi J, Rosner G, Fujita T, Heiss W-D (1995a) Halothane, but not alpha-chloralose, blocks potassium-evoked cortical spreading depression in cats. Brain Res 699:109-115
30. Saito R, Graf R, Rosner G, Hübel K, Fujita T, Heiss W-D (1995b) Halothane increases blood flow and reduces SD-like DC negativations and infarction in perifocal areas of focal ischemia in cats. J Cereb Blood Flow Metab (Suppl 1)15:S315
31. Shibata M, Siegfried B, Huston JP (1977) Miniature calomel electrode for recording DC potential changes accompanying spreading depression in the freely moving rat. Physiol Behav 18:1171-1174
32. Smith A, Hoff J, Nielsen S, Larson C (1974) Barbiturate protection in acute focal cerebral ischemia. Stroke 5:1-7
33. Somjen GG, Aitken PG, Czeh GL, Herreras O, Jing J, Young JN (1992) Mechanisms of spreading depression: a review of recent findings and a hypothesis. Can J Physiol Pharmacol 70:S248-S254
34. Sugaya E, Takato M, Noda Y (1975) Neuronal and glial activity during spreading depression in cerebral cortex of cat. J Neurophysiol 38: 822-841
35. Swanson RA, Morton MT, Tsao-Wu G, Savalos RA, Davidson C, Sharp FR (1990) A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab 10:290-293
36. Szerb JC (1991) Glutamate release and spreading depression in the fascia dentata in response to microdialysis with high K: role of glia. Brain Res 542:259-265
37. Todd MM, Warner DS (1992) A comfortable hypothesis reevaluated: cerebral metabolic depression and brain protection during ischemia. Anesthesiology 76:161-164
38. Tower DB (1954) Structural and functional organization of mammalian cerebral cortex: the correlation of neuronal density with brain size. J Comp Neurol 101:19-52
39. Van Harreveld A (1959) Compounds in brain extracts causing spreading depression of cerebral cortical activity and contraction of crustacean muscle. J Neurochem 3:300-315
40. Verhaegen MJ, Todd MM, Warner DS (1992) A comparison of cerebral ischemic flow thresholds during halothane/N20 and isoflurane/N20 anesthesia in rats. Anesthesiology 76:743-754
41. Warner DS, Ludwig PS, Pearlstein R, Brinkhous AD (1995) Halothane reduces focal ischemic injury in the rat when brain temperature is controlled. Anesthesiology 82:1237-1245
42. Warner DS, McFarlane C, Todd MM, Ludwig P, McAllister AM (1993) Sevoflurane and halothane reduce focal ischemic brain damage in the rat. Possible influence on thermoregulation. Anesthesiology 79:985-992
43. Winters WD, Spooner CE (1966) A neurophysiological comparison of alpha-chloralose with gamma-hydroxybutyrate in cats. EEG Clin Neurophysiol 20:83-90
44. Wollman H, Alexander SC, Cohen PJ, Chase PE, Melman E, Behar MG (1964) Cerebral circulation of man during halothane anesthesia: effects of hypocarbia and of d-tubocurarine. Anesthesiology 25:180-184