Ischaemic brain oedema

Journal of Clinical Neuroscience

Volumn 9, Issue 2, 2002, Pages 113-124

  Ayata, Cenk ^a   Ropper, Allan H ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BARBITURIC ACID DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCEROL; GLYCERYL TRINITRATE; HETASTARCH; HYDRALAZINE; INDOMETACIN; LABETALOL; MANNITOL; NITROPRUSSIDE SODIUM; PENTOBARBITAL; SODIUM CHLORIDE;

BLOOD BRAIN BARRIER; BLOOD PRESSURE REGULATION; BRAIN EDEMA; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; CRANIECTOMY; CYTOTOXICITY; DISEASE COURSE; DRUG EFFECT; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; FIBRINOLYTIC THERAPY; HUMAN; HYPERGLYCEMIA; HYPERTENSION; INFECTION; INTRACRANIAL PRESSURE; NEUROBIOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT MONITORING; PREDICTION; PRIORITY JOURNAL; REPERFUSION; REVIEW; STROKE;

EID: 0036242544     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1054/jocn.2001.1031     Document Type: Review

References (235)

1. Swelling of the brain following ischemic infarction with arterial occlusion
2. Brain edema after stroke. Clinical syndrome and intracranial pressure
3. 'Malignant' middle cerebral artery territory infarction: Clinical course and prognostic signs
4. Massive cerebral infarction with severe brain swelling: A clinicopathological study
5. Early mortality following stroke: A prospective review
6. Prognosis in middle cerebral artery occlusion
7. Middle cerebral artery territory infarction and early brain swelling: Progression and effect of age on outcome
8. Neurological deterioration in acute ischaemic stroke: Potential predictors and associated factors in the European cooperative acute stroke study (ECASS) I
9. Mechanisms and timing of deaths from cerebral infarction
10. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)
11. Early clinical and radiological predictors of fatal brain swelling in ischaemic stroke
12. Mass effect and death from severe acute stroke
13. Mortality of space-occupying ('malignant') middle cerebral artery infarction under conservative intensive care
14. Large hemispheric infarction, deterioration, and intracranial pressure
15. Outcome of acute supratentorial cerebral infarction in patients under 60. Development of a prognostic grading system
16. Prognostic factors in first-ever stroke in the carotid artery territory seen within 6 hours after onset
17. Prediction of long-term outcome in the early hours following acute ischemic stroke. Italian Acute Stroke Study Group
18. Causes and outcome of mechanical ventilation in patients with hemispheric ischemic stroke
19. The association of hyperglycemia with cerebral edema in stroke
20. Progressing neurological deficit secondary to acute ischemic stroke. A study on predictability, pathogenesis, and prognosis
21. The value of intracranial pressure monitoring in acute hemispheric stroke
22. Epidural cerebrospinal fluid pressure measurement and therapy of intracranial hypertension in 'malignant' middle cerebral artery infarct
23. Sensitivity and prognostic value of early CT in occlusion of the middle cerebral artery trunk
24. Early prediction of irreversible brain damage after ischemic stroke at CT
25. Acute ischemic strokes improving during the first 48 hours of onset: Predictability, outcome, and possible mechanisms. A comparison with early deteriorating strokes
26. Early CT signs in acute middle cerebral artery infarction: Predictive value for subsequent infarct locations and outcome
27. Lateral displacement of the brain and level of consciousness in patients with an acute hemispheral mass
28. A preliminary MRI study of the geometry of brain displacement and level of consciousness with acute intracranial masses
29. Brain shift, level of consciousness, and restoration of consciousness in patients with acute intracranial hematomas
30. Single-photon emission computed tomography and early death in acute ischemic stroke
31. Value of single-photon emission-computed tomography in acute stroke therapeutic trials
32. 99m technetium-ethyl-cysteinate-dimer single-photon emission CT can predict fatal ischemic brain edema
33. Quantitative measurement of cerebral blood flow by (99m) Tc-HMPAO SPECT in acute ischaemic stroke: Usefulness in determining therapeutic options
34. Relationship between cerebral blood flow and the development of swelling and life-threatening herniation in acute ischemic stroke
35. Fatal ischaemic brain oedema after early thrombolysis with tissue plasminogen activator in acute stroke
36. Does arterial recanalization improve outcome in carotid territory stroke?
37. Incidence of space-occupying brain edema following systemic thrombolysis of acute supratentorial ischemia
38. Thrombolysis in acute ischemic stroke: Does it work?
39. Role of a hydrostatic pressure gradient in the formation of early ischemic brain edema
40. Cortical tissue pressure gradients in early ischemic brain edema
41. Presidental address. Neuropathological aspects of brain edema
42. Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: A unifying hypothesis
43. Excitotoxic cell death
44. Serial MRI after transient focal cerebral ischemia in rats: Dynamics of tissue injury, blood-brain barrier damage, and edema formation
45. Early changes in blood brain barrier permeability to small molecules after transient cerebral ischemia
46. Experimental cerebral ischemia in Mongolian gerbils III. Behaviour of the blood-brain barrier
47. Hossmann KA Experimental brain infarcts in cats. II. Ischemic brain edema
48. Experimental regional cerebral ischemia in the middle cerebral artery territory in primates. Part 2: Effects on brain water and electrolytes in the early phase of MCA stroke
49. Experimental regional cerebral ischemia in the middle cerebral artery territory in primates. Part 3: Effects on brain water and electrolytes in the late phase of acute MCA stroke
50. Ischemic brain edema following occlusion of the middle cerebral artery in the rat. I: The time courses of the brain water, sodium and potassium contents and blood-brain barrier permeability to 1251-albumin
51. Blood-to-brain sodium transport in ischemic brain edema
52. Role of blood-brain barrier permeability in focal ischemic brain edema
53. Blood-brain barrier permeability to micromolecules and edema formation in the early phase of incomplete continuous ischemia
54. Cerebral edema after temporary and permanent middle cerebral artery occlusion in the rat
55. Biphasic opening of the blood-brain barrier following transient focal ischemia: Effects of hypothermia
56. Contributions of ions and albumin to the formation and resolution of ischemic brain edema
57. Early and late mechanisms of increased vascular permeability following experimental cerebral infarction
58. Edema and vascular permeability in cerebral ischemia: Comparison between ischemic neuronal damage and infarction
59. Opening of tight junctions in cerebral endothelium. I. Effect of hyperosmolar mannitol infused through the internal carotid artery
60. Opening of tight junctions in cerebral endothelium II. Effect of pressure-pulse induced acute arterial hypertension
61. Tight junctions of the blood-brain barrier
62. Time- and pressure-dependent changes in blood-brain barrier permeability after temporary middle cerebral artery occlusion in rats
63. Increased permeability of cerebral vessels to horseradish peroxidase induced by ischemia in Mongolian Gerbils
64. The blood-brain barrier to horseradish peroxidase under normal and experimental conditions
65. Duration of ischemia influences the development and resolution of ischemic brain edema
66. CBF time thresholds for the formation of ischemic cerebral edema, and effect of reperfusion in baboons
67. Ischemic brain edema with and without reperfusion: An experimental study in gerbils
68. Cerebral blood flow and edema following carotid occlusion in the gerbil
69. The role of free radicals and eicosanoids in the pathogenetic mechanism underlying ischemic brain edema
70. The role of hydrostatic pressure in ischemic brain edema
71. Reperfusion injury after focal cerebral ischemia: The role of inflammation and the therapeutic horizon
72. Blood-brain barrier disruption and exacerbation of ischemic brain edema after restoration of blood flow in experimental focal cerebral ischemia
73. Volume regulation of the brain tissue - A survey
74. Oedema-related tissue damage after temporary and permanent occlusion of the middle cerebral artery
75. Biomechanics of brain edema in acute cerebral ischemia in cats
76. Observations on penetration of serum proteins into the central nervous system
77. Brain water measured by magnetic resonance imaging. Correlation with direct estimation and changes after mannitol and dexamethasone
78. Clearance of edema fluid into cerebrospinal fluid. A mechanism for resolution of vasogenic brain edema
79. Pathophysiological aspects of brain edema
80. Vascular changes underlying cerebral lesions in stroke-prone spontaneously hypertensive rats. A serial section study
81. Cerebrovascular lesions in stroke-prone spontaneously hypertensive rats
82. Nerve cell injury in the brain of stroke-prone spontaneously hypertensive rats
83. New magnetic resonance imaging methods for cerebrovascular disease: Emerging clinical applications
84. Spreading of vasogenic edema and cytotoxic edema assessed by quantitative diffusion and T2 magnetic resonance imaging
85. Blood-brain barrier: Phenomenon of increasing importance to the imaging clinician
86. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons
87. Delayed hypoperfusion after incomplete forebrain ischemia in the rat. The role of polymorphonuclear leukocytes
88. Neutrophil as a mediator of ischemic edema formation in the brain
89. Neuroprotective effect of recombinant neutrophil inhibitory factor in transient focal cerebral ischaemia in the rat
90. Role of cell adhesion molecules in brain injury after transient middle cerebral artery occlusion in the rat
91. Possible involvement of interleukin-1 in ischemic brain edema formation
92. Transient increase of cytokine-induced neutrophil chemoattractant, a member of the interleukin-8 family, in ischemic rain areas after focal ischemia in rats
93. Preischemic but not postischemic zinc protoporphyrin treatment reduces infarct size and edema accumulation after temporary focal cerebral ischemia in rats
94. Prevention of cerebral edema and infarct in cerebral reperfusion injury by an antibody to interleukin-8
95. Proinflammatory cytokines and early neurological worsening in ischemic stroke
96. Role of oxidants in ischemic brain damage
97. Oxygen radical mechanisms of brain injury following ischemia and reperfusion
98. Nitric oxide donor-induced increase in permeability of the blood-brain barrier
99. Nitric oxide redox species exert differential permeability effects on the blood-brain barrier
100. Blockade of nitric oxide formation by N omega-nitro-L-arginine mitigates ischemic brain edema and subsequent cerebral infarction in rats
101. The effect of nitric oxide inhibition on ischemic brain edema
102. Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia
103. Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals
104. Background review and current concepts of reperfusion injury
105. Pathogenesis of vasogenic edema in focal cerebral ischemia. Role of superoxide radicals
106. Protective effects of superoxide dismutase on acute reperfusion injury of gerbil brain
107. Role of superoxide dismutase in ischemic brain injury: Reduction of edema and infarction in transgenic mice following focal cerebral ischemia
108. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase
109. Edema formation exacerbates neurological and histological outcomes after focal cerebral ischemia in CuZn-superoxide dismutase gene knockout mutant mice
110. Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains
111. Strong attenuation of ischemic and postischemic brain edema in rats by a novel free radical scavenger
112. Amelioration of ischaemic cerebral oedema by a free radical scavenger. AVS: 1.2-bis(nicotinamido)-propane. An experimental study using a regional ischaemia model in cats
113. Tirilazad reduces brain edema after middle cerebral artery ligation in hypertensive rats
114. Nitric oxide and blood-brain barrier integrity
115. Matrix metalloproteinases in cerebrovascular disease
116. Matrix metalloproteinases and diseases of the CNS
117. Serine proteases and brain damage-is there a link?
118. Ischemic brain edema
119. Proteolytic cascade enzymes increase in focal cerebral ischemia in rat
120. Vascular permeability factor/vascular endothelialgrowth factor, microvascular hyperpermeability, and angiogenesis
121. Vascular endothelial growth factor increases hydraulic conductivity of isolated perfused microvessels
122. VEGF increases permeability of the blood-brain barrier via a nitric oxide synthase/cGMP-dependent pathway
123. Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat
124. Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke
125. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke
126. VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain
127. Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system
128. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
129. Induction of brain edema following intracerebral injection of arachidonic acid
130. Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid
131. Effect of dexamethasone on serum protein extravasation in experimental brain infarcts of monkey: An immunohistochemical study
132. Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2
133. Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: Leukotriene C4 as a possible cause of cerebral edema
134. Prostaglandin synthesis and oedema formation during reperfusion following experimental brain ischaemia in the gerbil
135. Lipoxygenase metabolites of arachidonic acid and the development of ischaemic cerebral oedema
136. The role of bradykinin in mediating ischemic brain edema in rats
137. Mediators of cerebral edema
138. Mediators of vascular and parenchymal mechanisms in secondary brain damage
139. Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats
140. Effect of atrial natriuretic peptide on ischemic brain edema: Changes in brain water and electrolytes
141. Effects of atrial natriuretic peptide on ischemic brain edema in rats evaluated by proton magnetic resonance method
142. Cerebroprotective properties of SM-20220, a potent Na(+)/H(+) exchange inhibitor, in transient cerebral ischemia in rats
143. Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion
144. P/Q-type Ca2+ channel blocker omega-agatoxin IVA protects against brain injury after focal ischemia in rats
145. The metalloproteinase stromelysin-1 (transin) mediates PC12 cell growth cone invasiveness through basal laminae
146. Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix
147. Neovascularization with blood-brain barrier breakdown in delayed neuronal death
148. Cell proliferation after ischemic injury in gerbil brain. An immunocytochemical and autoradiographic study
149. Restoration of neurological function with induced hypertension in acute experimental cerebral ischaemia
150. Beneficial effects of induced hypertension on experimental stroke in awake monkeys
151. The effect of increased blood pressure on hemispheric lactate and water content during acute cerebral ischaemia in the rat and gerbil
152. Hypertension and hemodilution during cerebral ischemia reduce brain injury and edema
153. Delayed institution of hypertension during focal cerebral ischemia: Effect on brain edema
154. Induced hypertension during ischemia reduces infarct area after temporary middle cerebral artery occlusion in rats
155. The treatment of brain ischemia with vasopressor drugs
156. A pilot study of drug-induced hypertension for treatment of acute stroke
157. Autoregulation of cerebral blood flow in experimental focal brain ischemia
158. Induced hypertension treatment to improve cerebral ischemic injury after transient forebrain ischemia
159. Effect of hypertension on blood-brain barrier. Change after restoration of blood flow in post-ischemic gerbil brains. An electronmicroscopic study
160. Brain edema after middle cerebral artery occlusion. A comparison between normotensive and spontaneously hypertensive rats
161. Augmentation ofpostischemic brain damage by severe intermittent hypertension
162. Pial arterial pressure contribution to early ischemic brain edema
163. The prognostic value of admission blood pressure in patients with acute stroke
164. Pharmacological elevation of blood pressure in acute stroke. Clinical effects and safety
165. Induced hypertension as an approach to treating acute cerebrovascular ischaemia: Possibilities and limitations
166. Blood pressure and functional recovery in acute ischemic stroke
167. Should hypertension be treated after acute stroke? A randomized controlled trial using single photon emission computed tomography
168. Treatment modalities for hypertensive patients with intracranial pathology: Options and risks
169. Treatment of hypertension with labetalol in neurosurgical practice. Influence of labetalol on cerebral perfusion pressure in dogs without and with intracranial mass lesions
170. Angiotensin II receptor antagonist CV-11974 and cerebral blood flow autoregulation
171. Angiotensin converting enzyme inhibition and cerebral circulation - A review
172. Enalapril prevents imminent and reduces manifest cerebral edema in stroke-prone hypertensive rats
173. Alteration of intracranial pressure, cerebral blood flow, autoregulation and carbondioxide-reactivity by hypotensive agents in baboons with intracranial hypertension
174. Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice
175. Brain edema, autoregulation, and calcium antagonism. An experimental study with nimodipine
176. Brain edema
177. The immediate and long-term effects of mannitol and glycerol. A comparative experimental study
178. Aggravation of vasogenic cerebral edema by multiple-dose mannitol
179. Multiple-dose mannitol reduces brain water content in a rat model of cortical infarction
180. The effects of mannitol on cerebral edema after large hemispheric cerebral infarct
181. Cerebral perfusion pressure: A hemodynamic mechanism of mannitol and the postmannitol hemogram
182. Clinical study of mannitol and glycerol on raised intracranial pressure and on their rebound phenomenon
183. Intraventricular pressure after administration of dehydrating agents to severely brain-injured patients: Is there a rebound phenomenon?
184. The ambivalent effects of early and late administration of mannitol in cold-induced brain oedema
185. Mannitol: Potential for rebound intracranial hypertension?
186. Mannitol pharmacokinetics and serum osmolality in dogs and humans
187. Effects of mannitol on cerebral blood flow, blood pressure, blood viscosity, hematocrit, sodium, and potassium
188. Mannitol causes compensatory cerebral vasoconstriction and vasodilation in response to blood viscosity changes
189. Effect of mannitol on cerebrospinal fluid dynamics and brain tissue edema
190. Effect of mannitol on focal cerebral ischemia evaluated by magnetic resonance imaging
191. The effect of mannitol on experimental cerebral ischemia, revisited
192. Carnitine treatment for stroke in rats
193. Effect ofmannitol on experimental focal ischemia in awake monkeys
194. Guidelines for the management of patients with acute ischemic stroke: A statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association
195. Glycerol: A review of its pharmacology, pharmacokinetics, adverse reactions, and clinical use
196. Glycerol attenuates the adherence of leukocytes in rat pial venules after transient middle cerebral artery occlusion
197. Circulatory and metabolic effects of glycerol infusion in patients with recent cerebral infarction
198. The effect of isovolaemic haemodilution and intravenous glycerol on the sequelae of middle cerebral artery occlusion in the rat
199. Double-blind trial of glycerol therapy in early stroke
200. Double-blind randomised trial of intravenous glycerol in acute stroke
201. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial
202. Glycerol for acute ischaemic stroke
203. Human albumin therapy of acute ischemic stroke: Marked neuroprotective efficacy at moderate doses and with a broad therapeutic window
204. Unique features of albumin: A brief review
205. Long-term high-colloid oncotic therapy for ischemic brain edema in gerbils
206. Protein extravasation and cellular uptake after high-dose human-albumin treatment of transient focal cerebral ischemia in rats
207. Hypertonic saline as a safe and efficacious treatment of intracranial hypertension
208. Effects of hypertonic saline hydroxyethyl starch solution and mannitol in patients with increased intracranial pressure after stroke
209. High dose steroid treatment in cerebral infarction
210. Effect of steroid on ischemic brain edema. Analysis ofcytotoxic and vasogenic edema occurring during ischemia and after restoration of blood flow
211. Combined dexamethasone and low-molecular-weight dextran in acute brain infarction: Double-blind study
212. Indomethacin for brain edema following stroke
213. Are prostaglandins involved in experimental ischemic edema in gerbils?
214. Thiopental amelioration of brain damage after global ischemia in monkeys
215. Experimental brain ischemia: Protection from irreversible damage with a rapid-acting barbiturate (methohexital)
216. High dose barbiturates in non-traumatic brain swelling: ICP reduction and effect on outcome
217. Barbiturate coma in severe hemispheric stroke: Useful or obsolete?
218. Mass effect with cerebral infarction
219. Neurosurgical management of cerebellar haematoma and infarct
220. Decompressive surgery in space-occupying hemispheric infarction: Results of an open, prospective trial
221. One-year outcome after decompressive surgery for massive nondominant hemispheric infarction
222. Early hemicraniectomy in patients with complete middle cerebral artery infarction
223. An aggressive approach to massive middle cerebral artery infarction
224. Decompressive craniectomy for cerebral infarction. An experimental study in rats
225. Decompressive craniectomy in a rat model of 'malignant' cerebral hemispheric stroke: Experimental support for an aggressive therapeutic approach
226. Decompressive craniectomy, reperfusion, or a combination for early treatment of acute 'malignant' cerebral hemispheric stroke in rats? Potential mechanisms studied by MRI
227. Hemicraniectomy for acute massive cerebral infarction
228. Treatment of right hemispheric cerebral infarction by hemicraniectomy
229. Functional recovery after decompressive craniectomy for cerebral infarction
230. Hemicraniectomy in elderly patients with space occupying media infarction: Improved survival but poor functional outcome
231. Hemicraniectomy is a promising treatment in ischemic stroke
232. Temperature modulation of ischemic brain injury - A synthesis of recent advances
233. Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction
234. Focal cerebral ischemia in rats: Effect of hemodilution with alpha-alpha cross-linked hemoglobin on brain injury and edema
235. Haemodilution for acute ischaemic stroke