Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction

FEBS Journal

Volumn 278, Issue 13, 2011, Pages 2307-2317

  Kim, Tae Hoon ^a   Lee, Sang Ho ^a   Lee, Sun Mee ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

CYP450; HMGB1; Kupffer cells; sepsis; Toll like receptor

Indexed keywords

AMINOTRANSFERASE; BETA ACTIN; CD163 ANTIGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2E1; GADOLINIUM CHLORIDE; GLUTATHIONE; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; MESSENGER RNA; NEURONAL NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ACTIN GENE; CD163 GENE; CELL FUNCTION; CONTROLLED STUDY; CYTOCHROME P450 1A1 GENE; CYTOCHROME P450 1A2 GENE; CYTOCHROME P450 2B1 GENE; CYTOCHROME P450 2E1 GENE; ENZYME ACTIVITY; GENE; GENE EXPRESSION PROFILING; INTERLEUKIN 6 GENE; KUPFFER CELL; LIPID PEROXIDATION; LIVER METABOLISM; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SEPSIS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR ALPHA GENE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME-LINKED IMMUNOSORBENT ASSAY; GADOLINIUM; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; KUPFFER CELLS; LIPID PEROXIDATION; MALE; MICROSOMES, LIVER; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEPSIS; TRANSAMINASES;

RATTUS;

EID: 79959312365     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08148.x     Document Type: Article

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