The application of thermosensitive nanocarriers in controlled drug delivery

Journal of Nanomaterials

Volumn 2011, Issue , 2011, Pages

  Wang, Bochu ^a   Shao, Pengyu ^a   Wang, Yazhou ^a   Li, Jun ^a   Zhang, Yiqiong ^a  

^a CHONGQING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG-RELEASE RATE; ENHANCED PERMEABILITY AND RETENTION EFFECTS; FUNCTIONAL PROPERTIES; FUNCTIONALIZATIONS; FUTURE TRENDS; NANOCARRIERS; SITE-SPECIFIC; SMART DRUG DELIVERY SYSTEMS; SPECIAL PROPERTIES; THERMO SENSITIVE; THERMO-SENSITIVE POLYMER;

FUNCTIONAL POLYMERS;

CONTROLLED DRUG DELIVERY;

EID: 79959195041     PISSN: 16874110     EISSN: 16874129     Source Type: Journal    
DOI: 10.1155/2011/389640     Document Type: Review

References (115)

1. Hughes G. A., Nanostructure-mediated drug delivery Nanomedicine: Nanotechnology, Biology, and Medicine 2005 1 1 22 30 (Pubitemid 43963612)
2. Kumari A., Yadav S. K., Yadav S. C., Biodegradable polymeric nanoparticles based drug delivery systems Colloids and Surfaces B 2010 75 1 1 18
3. Rawat M., Singh D., Saraf S., Nanocarriers: promising vehicle for bioactive drugs Biological and Pharmaceutical Bulletin 2006 29 9 1790 1798 (Pubitemid 44338396)
4. Peer D., Karp J. M., Hong S., Farokhzad O. C., Margalit R., Langer R., Nanocarriers as an emerging platform for cancer therapy Nature Nanotechnology 2007 2 12 751 760 (Pubitemid 350223348)
5. Ravi Kumar M. N. V., Bakowsky U., Lehr C. M., Preparation and characterization of cationic PLGA nanospheres as DNA carriers Biomaterials 2004 25 10 1771 1777 (Pubitemid 38102253)
6. Li S. D., Huang L., Pharmacokinetics and biodistribution of nanoparticles Molecular Pharmaceutics 2008 5 4 496 504
7. Chang C., Wei H., Quan C. Y., Li Y. Y., Liu J., Wang Z. C., Cheng SI. X., Zhang X. Z., Zhuo R. X., Fabrication of thermosensitive PCL-PNIPAAm-PCL triblock copolymeric micelles for drug delivery Journal of Polymer Science A 2008 46 9 3048 3057 (Pubitemid 351579058)
8. Chung H. J., Park T. G., Self-assembled and nanostructured hydrogels for drug delivery and tissue engineering Nano Today 2009 4 5 429 437
9. de Smet M., Langereis S., den Bosch S. V., Grll H., Temperature-sensitive liposomes for doxorubicin delivery under MRI guidance Journal of Controlled Release 2010 143 1 120 127
10. Sahoo S. K., Labhasetwar V., Nanotech approaches to drug delivery and imaging Drug Discovery Today 2003 8 24 1112 1120 (Pubitemid 37547917)
11. Ganta S., Devalapally H., Shahiwala A., Amiji M., A review of stimuli-responsive nanocarriers for drug and gene delivery Journal of Controlled Release 2008 126 3 187 204
12. Torchilin V., Tumor delivery of macromolecular drugs based on the EPR effect Advanced Drug Delivery Reviews 2010 63 3 131 135
13. Torchilin V. P., Multifunctional nanocarriers Advanced Drug Delivery Reviews 2006 58 14 1532 1555 (Pubitemid 44822608)
14. Langer R., Drugs on target Science 2001 293 5527 58 59 (Pubitemid 32625490)
15. Sung J. C., Pulliam B. L., Edwards D. A., Nanoparticles for drug delivery to the lungs Trends in Biotechnology 2007 25 12 563 570 (Pubitemid 350138179)
16. Paasonen L., Laaksonen T., Johans C., Yliperttula M., Kontturi K., Urtti A., Gold nanoparticles enable selective light-induced contents release from liposomes Journal of Controlled Release 2007 122 1 86 93 (Pubitemid 47284557)
17. Deo S. K., Moschou E. A., Peteu S. F., Bachas L. G., Daunert S., Eisenhardt P. E., Madou M. J., Responsive drug delivery systems Analytical Chemistry 2003 75 9 206A 213A (Pubitemid 36542330)
18. Casadei M. A., Pitarresi G., Calabrese R., Paolicelli P., Giammona G., Biodegradable and pH-sensitive hydrogels for potential colon-specific drug delivery: characterization and in vitro release studies Biomacromolecules 2008 9 1 43 49 (Pubitemid 351201580)
19. Chen S., Li Y., Guo C., Wang J., Ma J., Liangs X., Yang L. R., Liu H. Z., Temperature-responsive magnetite/PEOPPOPEO block copolymer nanoparticles for controlled drug targeting delivery Langmuir 2007 23 25 12669 12676 (Pubitemid 350275586)
20. Qiu Y., Park K., Environment-sensitive hydrogels for drug delivery Advanced Drug Delivery Reviews 2001 53 3 321 339 (Pubitemid 34024913)
21. Loh X. J., Peh P., Liao S., Sng C., Li J., Controlled drug release from biodegradable thermoresponsive physical hydrogel nanofibers Journal of Controlled Release 2010 143 2 175 182
22. Kim S., Kim J. H., Jeon O., Kwon I. C., Park K., Engineered polymers for advanced drug delivery European Journal of Pharmaceutics and Biopharmaceutics 2009 71 3 420 430
23. Li J., Wang B. C., Wang Y. Z., Thermo-sensitive polymers for controlled-release drug delivery systems International Journal of Pharmacology 2006 2 5 513 519
24. Bajpai A. K., Shukla S. K., Bhanu S., Kankane S., Responsive polymers in controlled drug delivery Progress in Polymer Science 2008 33 11 1088 1118
25. Schmaljohann D., Thermo- and pH-responsive polymers in drug delivery Advanced Drug Delivery Reviews 2006 58 15 1655 1670 (Pubitemid 44830149)
26. Kost J., Langer R., Responsive polymeric delivery systems Advanced Drug Delivery Reviews 2001 46 13 125 148 (Pubitemid 33653418)
27. Gil E. S., Hudson S. M., Stimuli-reponsive polymers and their bioconjugates Progress in Polymer Science 2004 29 12 1173 1222
28. Kono K., Murakami T., Yoshida T., Haba Y., Kanaoka S., Takagishi T., Aoshima S., Temperature sensitization of liposomes by use of thermosensitive block copolymers synthesized by living cationic polymerization: effect of copolymer chain length Bioconjugate Chemistry 2005 16 6 1367 1374 (Pubitemid 41681502)
29. Hu H., Fan X. D., Cao Z. L., Thermo- and pH-sensitive dendrimer derivatives with a shell of poly(N,N-dimethylaminoethyl methacrylate) and study of their controlled drug release behavior Polymer 2005 46 22 9514 9522
30. Kohori F., Sakai K., Aoyagi T., Yokoyama M., Yamato M., Sakurai Y., Okano T., Control of adriamycin cytotoxic activity using thermally responsive polymeric micelles composed of poly(N-isopropylacrylamide-co-N,N- dimethylacrylamide)-b-poly(D,L-lactide) Colloids and Surfaces B 1999 16 14 195 205 (Pubitemid 29486806)
31. Nakayama M., Okano T., Miyazaki T., Kohori F., Sakai K., Yokoyama M., Molecular design of biodegradable polymeric micelles for temperature-responsive drug release Journal of Controlled Release 2006 115 1 46 56 (Pubitemid 44419528)
32. Kimura M., Kato M., Muto T., Hanabusa K., Shirai H., Temperature- sensitive dendritic hosts: synthesis, characterization, and control of catalytic activity Macromolecules 2000 33 4 1117 1119 (Pubitemid 30589081)
33. Hayashi H., Kono K., Takfagishi T., Temperature sensitization of liposomes using copolymers of N-isopropylacrylamide Bioconjugate Chemistry 1999 10 3 412 418 (Pubitemid 29243323)
34. Ebara M., Aoyagi T., Sakai K., Okano T., Introducing reactive carboxyl side chains retains phase transition temperature sensitivity in N-isopropylacrylamide copolymer gels Macromolecules 2000 33 22 8312 8316
35. Aathimanikandan S. V., Savariar E. N., Thayumanavan S., Temperature-sensitive dendritic micelles Journal of the American Chemical Society 2005 127 42 14922 14929 (Pubitemid 41511029)
36. Yang C., Ni X., Li J., New thermogelling copolymers composed of heptakis(2,6-di-O-methyl)- -cyclodextrin, poly(propylene glycol), and poly(ethylene glycol) Journal of Materials Chemistry 2009 19 1 3755 3763
37. Chung J. E., Yokoyama M., Yamato M., Aoyagi T., Sakurai Y., Okano T., Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate) Journal of Controlled Release 1999 62 1-2 115 127 (Pubitemid 29486490)
38. Loh X. J., Zhang Z. X., Wu Y. L., Lee T. S., Li J., Synthesis of novel biodegradable thermoresponsive triblock copolymers based on poly[(R)-3- hydroxybutyrate] and poly(N-isopropylacrylamide) and their formation of thermoresponsive micelles Macromolecules 2009 42 1 194 202
39. Liu P., Wang B., Qiao W., Li J., Novel thermosensitive nano-micelles from triblock copolymer for drug delivery Journal of Biomedical Nanotechnology 2009 5 3 310 313
40. He C., Kim S. W., Lee D. S., In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery Journal of Controlled Release 2008 127 3 189 207
41. Haba Y., Kojima C., Harada A., Kono K., Comparison of thermosensitive properties of poly(amidoamine) dendrimers with peripheral N-isopropylamide groups and linear polymers with the same groups Angewandte Chemie: International Edition 2007 46 1-2 234 237 (Pubitemid 46071708)
42. Hashimoto K., Sakamoto J., Tanii H., Neurotoxicty of acrylamide and related compounds and their effects on male gonads in mice Archives of Toxicology 1981 47 3 179 189 (Pubitemid 11072976)
43. Loh X. J., Goh S. H., Li J., New biodegradable thermogelling copolymers having very low gelation concentrations Biomacromolecules 2007 8 2 585 593 (Pubitemid 46323277)
44. Loh X. J., Tan Y. X., Li Z., Teo L. S., Goh S. H., Li J., Biodegradable thermogelling poly(ester urethane)s consisting of poly(lactic acid)thermodynamics of micellization and hydrolytic degradation Biomaterials 2008 29 14 2164 2172
45. Loh X. J., Colin Sng K. B., Li J., Synthesis and water-swelling of thermo-responsive poly(ester urethane)s containing polycaprolactone, poly(ethylene glycol) and poly(propylene glycol) Biomaterials 2008 29 22 3185 3194
46. Gong C., Shi S., Dong P., Kan B., Gou M., Wang X., Li X., Luo F., Zhao X., Wei Y., Qian Z., Synthesis and characterization of PEG-PCL-PEG thermosensitive hydrogel International Journal of Pharmaceutics 2009 365 1-2 89 99
47. Loh X. J., Goh S. H., Li J., Hydrolytic degradation and protein release studies of thermogelling polyurethane copolymers Biomaterials 2007 28 28 4113 4123
48. Loh X. J., Goh S. H., Li J., Biodegradable thermogelling poly[(R)-3-hydroxybutyrate]-based block copolymers: micellization, gelation, and cytotoxicity and cell culture studies Journal of Physical Chemistry B 2009 113 35 11822 11830
49. Riess G., Micellization of block copolymers Progress in Polymer Science 2003 28 7 1107 1170
50. Kwon G. S., Okano T., Polymeric micelles as new drug carriers Advanced Drug Delivery Reviews 1996 21 2 107 116 (Pubitemid 26401713)
51. Tian H. Y., Deng C., Lin H., Sun J., Deng M., Chen X., Jing X., Biodegradable cationic PEG-PEI-PBLG hyperbranched block copolymer: synthesis and micelle characterization Biomaterials 2005 26 20 4209 4217 (Pubitemid 40430847)
52. Jeong J. H., Park T. G., Poly(L-lysine)-g-poly(D,L-lactic-co-glycolic acid) micelles for low cytotoxic biodegradable gene delivery carriers Journal of Controlled Release 2002 82 1 159 166 (Pubitemid 34775057)
53. Otsuka H., Nagasaki Y., Kataoka K., PEGylated nanoparticles for biological and pharmaceutical applications Advanced Drug Delivery Reviews 2003 55 3 403 419 (Pubitemid 36293792)
54. Harada A., Kataoka K., Supramolecular assemblies of block copolymers in aqueous media as nanocontainers relevant to biological applications Progress in Polymer Science 2006 31 11 949 982 (Pubitemid 44738012)
55. Qiu L. Y., Bae Y. H., Self-assembled polyethylenimine-graft-poly( -caprolactone) micelles as potential dual carriers of genes and anticancer drugs Biomaterials 2007 28 28 4132 4142 (Pubitemid 47048375)
56. Cheng C., Wei H., Shi B. X., Cheng H., Li C., Gu Z. W., Cheng SI. X., Zhang X. Z., Zhuo R. X., Biotinylated thermoresponsive micelle self-assembled from double-hydrophilic block copolymer for drug delivery and tumor target Biomaterials 2008 29 4 497 505 (Pubitemid 350100795)
57. Cai S., Vijayan K., Cheng D., Lima E. M., Discher D. E., Micelles of different morphologiesadvantages of worm-like filomicelles of PEO-PCL in paclitaxel delivery Pharmaceutical Research 2007 24 11 2099 2109 (Pubitemid 47493571)
58. Cabral H., Nishiyama N., Okazaki S., Koyama H., Kataoka K., Preparation and biological properties of dichloro(1,2-diaminocyclohexane) platinum(II) (DACHPt)-loaded polymeric micelles Journal of Controlled Release 2005 101 13 223 232 (Pubitemid 39600985)
59. Choi C., Chae S. Y., Nah J. W., Thermosensitive poly(N- isopropylacrylamide)-b-poly( {lunate}-caprolactone) nanoparticles for efficient drug delivery system Polymer 2006 47 13 4571 4580 (Pubitemid 43870230)
60. Liu S. Q., Tong Y. W., Yang Y. Y., Incorporation and in vitro release of doxorubicin in thermally sensitive micelles made from poly(N- isopropylacrylamide-co-N,N-dimethylacrylamide)-b- poly(D,L-lactide-co-glycolide) with varying compositions Biomaterials 2005 26 24 5064 5074 (Pubitemid 40354239)
61. Soga O., Van Nostrum C. F., Fens M., Rijcken C. J. F., Schiffelers R. M., Storm G., Hennink W. E., Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery Journal of Controlled Release 2005 103 2 341 353 (Pubitemid 40342534)
62. Rijcken C. J. F., Schiffelers R. M., van Nostrum C. F., Hennink W. E., Long circulating biodegradable polymeric micelles: towards targeted drug delivery Journal of Controlled Release 2008 132 3 e19 e36
63. Rijcken C. J., Snel C. J., Schiffelers R. M., van Nostrum C. F., Hennink W. E., Hydrolysable core-crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies Biomaterials 2007 28 36 5581 5593 (Pubitemid 47599643)
64. Cammas S., Suzuki K., Sone C., Sakurai Y., Kataoka K., Okano T., Thermo-responsive polymer nanoparticles with a core-shell micelle structure as site-specific drug carriers Journal of Controlled Release 1997 48 1-2 157 164 (Pubitemid 27401974)
65. Chung J. E., Yokoyama M., Okano T., Inner core segment design for drug delivery control of thermo-responsive polymeric micelles Journal of Controlled Release 2000 65 1-2 93 103 (Pubitemid 30122919)
66. Wei H., Zhang X., Cheng C., Cheng S. X., Zhuo R. X., Self-assembled, thermosensitive micelles of a star block copolymer based on PMMA and PNIPAAm for controlled drug delivery Biomaterials 2007 28 1 99 107 (Pubitemid 44427903)
67. Nakayama M., Chung J. E., Miyazaki T., Yokoyama M., Sakai K., Okano T., Thermal modulation of intracellular drug distribution using thermoresponsive polymeric micelles Reactive and Functional Polymers 2007 67 11 1398 1407 (Pubitemid 47566457)
68. Takeda N., Nakamura E., Yokoyama M., Okano T., Temperature-responsive polymeric carriers incorporating hydrophobic monomers for effective transfection in small doses Journal of Controlled Release 2004 95 2 343 355 (Pubitemid 38230048)
69. Kurisawa M., Yokoyama M., Okano T., Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers Journal of Controlled Release 2000 68 1 1 8 (Pubitemid 30407057)
70. Rijcken C. J. F., Soga O., Hennink W. E., van Nostrum C. F., Triggered destabilisation of polymeric micelles and vesicles by changing polymers polarity: an attractive tool for drug delivery Journal of Controlled Release 2007 120 3 131 148 (Pubitemid 47058635)
71. Wei H., Cheng S. X., Zhang X. Z., Zhuo R. X., Thermo-sensitive polymeric micelles based on poly(N-isopropylacrylamide) as drug carriers Progress in Polymer Science 2009 34 9 893 910
72. Liu B., Yang M., Li R., Ding Y., Qian X., Yu L., Jiang X., The antitumor effect of novel docetaxel-loaded thermosensitive micelles European Journal of Pharmaceutics and Biopharmaceutics 2008 69 2 527 534
73. Rapoport N., Combined cancer therapy by micellar-encapsulated drug and ultrasound International Journal of Pharmaceutics 2004 277 1-2 155 162 (Pubitemid 38670430)
74. Yokoyama M., Okano T., Introduction: targetable drug carriers: present status and a future perspective Advanced Drug Delivery Reviews 1996 21 2 77 80 (Pubitemid 26401711)
75. Peppas N. A., Hilt J. Z., Khademhosseini A., Langer R., Hydrogels in biology and medicine: from molecular principles to bionanotechnology Advanced Materials 2006 18 11 1345 1360 (Pubitemid 43898575)
76. Hamidi M., Azadi A., Rafiei P., Hydrogel nanoparticles in drug delivery Advanced Drug Delivery Reviews 2008 60 15 1638 1649
77. Fang J. Y., Chen J. P., Leu Y. L., Hu J. W., Temperature-sensitive hydrogels composed of chitosan and hyaluronic acid as injectable carriers for drug delivery European Journal of Pharmaceutics and Biopharmaceutics 2008 68 3 626 636
78. Choi S., Kim S. W., Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats Pharmaceutical Research 2003 20 12 2008 2010 (Pubitemid 38005533)
79. Choi S. W., Kim J. H., Design of surface-modified poly(d,l-lactide-co- glycolide) nanoparticles for targeted drug delivery to bone Journal of Controlled Release 2007 122 1 24 30
80. Rapoport N., Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery Progress in Polymer Science 2007 32 8-9 962 990 (Pubitemid 47198285)
81. Li J., Wang B., Wang Y., Liu P., Qiao W., Preparation and characterization of thermosensitive nanoparticles for targeted drug delivery Journal of Macromolecular Science A 2008 45 10 833 838
82. Li J., Wang B., Liu P., Possibility of active targeting to tumor by local hyperthermia with temperature-sensitive nanoparticles Medical Hypotheses 2008 71 2 249 251
83. Felnerova D., Viret J. F., Glck R., Moser C., Liposomes and virosomes as delivery systems for antigens, nucleic acids and drugs Current Opinion in Biotechnology 2004 15 6 518 529 (Pubitemid 39551004)
84. Guo X., Szoka F. C., Chemical approaches to triggerable lipid vesicles for drug and gene delivery Accounts of Chemical Research 2003 36 5 335 341
85. Kono K., Thermosensitive polymer-modified liposomes Advanced Drug Delivery Reviews 2001 53 3 307 319 (Pubitemid 34024912)
86. Dromi S., Frenkel V., Luk A., Traughber B., Angstadt M., Bur M., Poff J., Xie J., Libutti S. K., Li K. C. P., Wood B. J., Pulsed-high intensity focused ultrasound and low temperaturesensitive liposomes for enhanced targeted drug delivery and antitumor effect Clinical Cancer Research 2007 13 9 2722 2727 (Pubitemid 46788041)
87. Hauck M. L., La Rue S. M., Petros W. P., Poulson J. M., Yu D., Spasojevic I., Pruitt A. F., Klein A., Case B., Thrall D. E., Needham D., Dewhirst M. W., Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors Clinical Cancer Research 2006 12 13 4004 4010 (Pubitemid 44078087)
88. Yuyama Y., Tsujimoto M., Fujimoto Y., Oku N., Potential usage of thermosensitive liposomes for site-specific delivery of cytokines Cancer Letters 2000 155 1 71 77 (Pubitemid 30256227)
89. Chen W. H., Regen S. L., Thermally gated liposomes Journal of the American Chemical Society 2005 127 18 6538 6539 (Pubitemid 40664153)
90. Hosokawa T., Sami M., Kato Y., Hayakawa E., Alteration in the temperature-dependent content release property of thermosensitive liposomes in plasma Chemical and Pharmaceutical Bulletin 2003 51 11 1227 1232 (Pubitemid 41685575)
91. Lindner L. H., Eichhorn M. E., Eibl H., Teichert N., Schmitt-Sody M., Issels R. D., Dellian M., Novel temperature-sensitive liposomes with prolonged circulation time Clinical Cancer Research 2004 10 6 2168 2178 (Pubitemid 38375579)
92. Chen Q., Tong S., Dewhirst M. W., Yuan F., Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome Molecular Cancer Therapeutics 2004 3 10 1311 1317 (Pubitemid 39440175)
93. Needham D., Anyarambhatla G., Kong G., Dewhirst M. W., A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model Cancer Research 2000 60 5 1197 1201 (Pubitemid 30151982)
94. Han H. D., Choi M. S., Hwang T., Song C. K., Seong H., Kim T. W., Choi HO. S., Shin B. C., Hyperthermia-induced antitumor activity of thermosensitive polymer modified temperature-sensitive liposomes Journal of Pharmaceutical Sciences 2006 95 9 1909 1917 (Pubitemid 44433023)
95. Gupta U., Agashe H. B., Asthana A., Jain N. K., A review of in vitro-in vivo investigations on dendrimers: the novel nanoscopic drug carriers Nanomedicine: Nanotechnology, Biology, and Medicine 2006 2 2 66 73 (Pubitemid 43956608)
96. Svenson S., Dendrimers as versatile platform in drug delivery applications European Journal of Pharmaceutics and Biopharmaceutics 2009 71 3 445 462
97. Tono Y., Kojima C., Haba Y., Takahashi T., Harada A., Yagi S., Kono K., Thermosensitive properties of poly(amidoamine) dendrimers with peripheral phenylalanine residues Langmuir 2006 22 11 4920 4922 (Pubitemid 44012053)
98. Sun G., Guan Z., Synthesis and investigation of core-shell dendritic nanoparticles with tunable thermosensitivity Macromolecules 2010 43 23 9668 9673
99. Haba Y., Kojima C., Harada A., Kono K., Control of temperature-sensitive properties of poly(amidoamine) dendrimers using peripheral modification with various alkylamide groups Macromolecules 2006 39 21 7451 7453 (Pubitemid 44807691)
100. You Y. Z., Hong C. Y., Pan C. Y., Wang P. H., Synthesis of a dendritic core-shell nanostructure with a temperature-sensitive shell Advanced Materials 2004 16 21 1953 1957
101. Haba Y., Harada A., Takagishi T., Kono K., Rendering poly(amidoamine) or poly(propylenimine) dendrimers temperature sensitive Journal of the American Chemical Society 2004 126 40 12760 12761 (Pubitemid 39372289)
102. Xu J., Luo S., Shi W., Liu S., Two-stage collapse of unimolecular micelles with double thermoresponsive coronas Langmuir 2006 22 3 989 997 (Pubitemid 43282159)
103. Zhang X. Z., Sun G. M., Chu C. C., Temperature sensitive dendrite-shaped PNIPAAm/Dex-AI hybrid hydrogel particles: formulation and properties European Polymer Journal 2004 40 9 2251 2257
104. Zhang J. T., Huang S. W., Zhuo R. X., Temperature-sensitive polyamidoamine dendrimer/poly(N-isopropylacrylamide) hydrogels with improved responsive properties Macromolecular Bioscience 2004 4 6 575 578
105. Li W., Zhang A., Feldman K., Walde P., Schlter A. D., Thermoresponsive dendronized polymers Macromolecules 2008 41 10 3659 3667
106. Chen J., Liu M., Liu H., Ma L., Synthesis, swelling and drug release behavior of poly(N,N-diethylacrylamide-co-N-hydroxymethyl acrylamide) hydrogel Materials Science and Engineering C 2009 29 7 2116 2123
107. Qiao P., Niu Q., Wang Z., Cao D., Synthesis of thermosensitive micelles based on poly(N-isopropylacrylamide) and poly(l-alanine) for controlled release of adriamycin Chemical Engineering Journal 2010 159 13 257 263
108. Kono K., Ozawa T., Yoshida T., Ozaki F., Ishizaka Y., Maruyama K., Kojima C., Harada A., Aoshima S., Highly temperature-sensitive liposomes based on a thermosensitive block copolymer for tumor-specific chemotherapy Biomaterials 2010 31 27 7096 7105
109. Dimitrov I., Trzebicka B., Mller A. H. E., Dworak A., Tsvetanov C. B., Thermosensitive water-soluble copolymers with doubly responsive reversibly interacting entities Progress in Polymer Science 2007 32 11 1275 1343 (Pubitemid 47513189)
110. Zhang Z. X., Liu X., Xu F. J., Loh X. J., Kang EN. T., Neon K. G., Li J., Pseudo-block copolymer based on star-shaped poly(N-isopropylacrylamide) with a -cyclodextrin core and guest-bearing PEG: controlling thermoresponsivity through supramolecular self-assembly Macromolecules 2008 41 16 5967 5970
111. Velthoen I. W., Beek J. V., Dijkstra P. J., Feijen J., Thermo-responsive hydrogels based on highly branched poly(ethylene glycol)poly(L-lactide) copolymers Reactive and Functional Polymers 2011 71 3 245 253
112. Soppimath K. S., Liu L. H., Seow W. Y., Lin S. Q., Powell R., Chan P., Yang Y. Y., Multifunctional core/shell nanoparticles self-assembled from pH-induced thermosensitive polymers for targeted intracellular anticancer drug delivery Advanced Functional Materials 2007 17 3 355 362
113. Akimoto J., Nakayama M., Sakai K., Okano T., Thermally controlled intracellular uptake system of polymeric micelles possessing oly(N-isopropylacrylamide)-based outer coronas Molecular Pharmaceutics 2010 7 4 926 935
114. Rastogi R., Gulati N., Kotnala R. K., Evaluation of folate conjugated pegylated thermosensitive magnetic nanocomposites for tumor imaging and therapy Colloids and Surfaces B 2011 82 1 160 167
115. Kono K., Nakashima S., Kokuryo D., Multi-functional liposomes having temperature-triggered release and magnetic resonance imaging for tumor-specific themotherapy Biomaterials 2011 32 5 1387 1395