Controlled drug release from biodegradable thermoresponsive physical hydrogel nanofibers

Journal of Controlled Release

Volumn 143, Issue 2, 2010, Pages 175-182

  Loh, Xian Jun ^a,b,c   Peh, Priscilla ^a   Liao, Susan ^a   Sng, Colin ^c   Li, Jun ^a,b,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

Author keywords

Block copolymers; Controlled release; Human dermal fibroblast cells; Hydrogel; Nanofiber; Thermosensitive; Tissue engineering

Indexed keywords

BUFFER SOLUTIONS; CAPROLACTONE; CELL MORPHOLOGY; COLD CONDITIONS; CONTROLLED DRUG RELEASE; CONTROLLED RELEASE; HIGHER TEMPERATURES; HUMAN DERMAL FIBROBLAST CELLS; HUMAN DERMAL FIBROBLASTS; HYDROLYTIC DEGRADATION; MULTIBLOCKS; NANOFIBER MATS; NANOFIBER SCAFFOLD; PCL NANOFIBERS; POLYESTERURETHANES; POLYPROPYLENE GLYCOL; PROTEIN RELEASE; SKIN TISSUE ENGINEERING; SUPPORTING STRUCTURE; THERMO SENSITIVE; THERMO-RESPONSIVE; VIABLE CELLS;

ADHESION; ANIMAL CELL CULTURE; BIOMATERIALS; BLOCK COPOLYMERS; CELL ADHESION; CELL CULTURE; COPOLYMERIZATION; ESTERS; ETHYLENE; ETHYLENE GLYCOL; FIBROBLASTS; GRAFTING (CHEMICAL); HYDROPHILICITY; NANOFIBERS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROPYLENE; SCAFFOLDS; TISSUE; TISSUE ENGINEERING;

HYDROGELS;

BOVINE SERUM ALBUMIN; BUFFER; MACROGOL; MOLECULAR SCAFFOLD; NANOFIBER; POLYCAPROLACTONE; POLYMER; POLYPROPYLENE GLYCOL; UNCLASSIFIED DRUG; WATER;

ABSORPTION; ARTICLE; BIODEGRADABILITY; CELL ADHESION; CELL STRUCTURE; COLD EXPOSURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; HEAT SENSITIVITY; HIGH TEMPERATURE; HUMAN; HUMAN CELL; HYDROGEL; HYDROLYSIS; HYDROPHILICITY; NANOFABRICATION; PRIORITY JOURNAL; PROTEIN SECRETION; SKIN FIBROBLAST; TISSUE ENGINEERING;

ANIMALS; CATTLE; CELL ADHESION; CELL SURVIVAL; CELLS, CULTURED; DELAYED-ACTION PREPARATIONS; FIBROBLASTS; HUMANS; HYDROGEL; NANOFIBERS; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; POLYURETHANES; PROPYLENE GLYCOLS; SERUM ALBUMIN, BOVINE; TEMPERATURE;

EID: 77950342031     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.12.030     Document Type: Article

References (55)

1. Li W.J., Laurencin C.T., Caterson E.J., Tuan R.S., Ko F.K. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. Journal of Biomedical Materials Research 2002, 60(4):613-621.
2. Yoshimoto H., Shin Y.M., Terai H., Vacanti J.P. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003, 24(12):2077-2082.
3. Zhang S.G. Fabrication of novel biomaterials through molecular self-assembly. Nature Biotechnology 2003, 21(10):1171-1178.
4. Chambers A., Park C., Baker R.T.K., Rodriguez N.M. Hydrogen storage in graphite nanofibers. Journal of Physical Chemistry B 1998, 102(22):4253-4256.
5. Bessel C.A., Laubernds K., Rodriguez N.M., Baker R.T.K. Graphite nanofibers as an electrode for fuel cell applications. Journal of Physical Chemistry B 2001, 105(6):1115-1118.
6. Tseng R.J., Huang J.X., Ouyang J., Kaner R.B., Yang Y. Polyaniline nanofiber/gold nanoparticle nonvolatile memory. Nano Letters 2005, 5(6):1077-1080.
7. Park C., Baker R.T.K. Catalytic behavior of graphite nanofiber supported nickel particles. 2. The influence of the nanofiber structure. Journal of Physical Chemistry B 1998, 102(26):5168-5177.
8. Subbiah T., Bhat G.S., Tock R.W., Pararneswaran S., Ramkumar S.S. Electrospinning of nanofibers. Journal of Applied Polymer Science 2005, 96(2):557-569.
9. Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nature Biotechnology 2005, 23(1):47-55.
10. Abrams G.A., Murphy C.J., Wang Z.Y., Nealey P.F., Bjorling D.E. Ultrastructural basement membrane topography of the bladder epithelium. Urological Research 2003, 31(5):341-346.
11. Abrams G.A., Goodman S.L., Nealey P.F., Franco M., Murphy C.J. Nanoscale topography of the basement membrane underlying the corneal epithelium of the rhesus macaque. Cell and Tissue Research 2000, 299(1):39-46.
12. Elsdale T., Bard J. Collagen substrata for studies on cell behavior. The Journal of Cell Biology 1972, 54:626-637.
13. Nisbet D.R., Crompton K.E., Horne M.K., Finkelstein D.I., Forsythe J.S. Neural tissue engineering of the CNS using hydrogels. Journal of Biomedical Materials Research Part B-Applied Biomaterials 2008, 87B(1):251-263.
14. Chew S.Y., Mi R.F., Hoke A., Leong K.W. Aligned protein-polymer composite fibers enhance nerve regeneration: a potential tissue-engineering platform. Advanced Functional Materials 2007, 17(8):1288-1296.
15. Liao I.C., Chew S.Y., Leong K.W. Aligned core-shell nanofibers delivering bioactive proteins. Nanomedicine 2006, 1(4):465-471.
16. Chew S.Y., Wen J., Yim E.K.F., Leong K.W. Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules 2005, 6(4):2017-2024.
17. Ji Y., Ghosh K., Li B.Q., Sokolov J.C., Clark R.A.F., Rafailovich M.H. Dual-syringe reactive electrospinning of cross-linked hyaluronic acid hydrogel nanofibers for tissue engineering applications. Macromolecular Bioscience 2006, 6(10):811-817.
18. Liu H.Q., Zhen M., Wu R.H. Ionic-strength- and pH-responsive poly[acrylamide-co-(maleilc acid)] hydrogel nanofibers. Macromolecular Chemistry and Physics 2007, 208(8):874-880.
19. Tang C.Y., Ye S.H., Liu H.Q. Electrospinning of poly(styrene-co-maleic anhydride) (SMA) and water-swelling behavior of crosslinked/hydrolyzed SMA hydrogel nanofibers. Polymer 2007, 48(15):4482-4491.
20. Loh X.J., Sng K.B.C., Li J. Synthesis and water-swelling of thermo-responsive poly(ester urethane)s containing poly(epsilon-caprolactone), poly(ethylene glycol) and poly(propylene glycol). Biomaterials 2008, 29(22):3185-3194.
21. Loh X.J., Goh S.H., Li J. Hydrolytic degradation and protein release studies of thermogelling polyurethane copolymers consisting of poly[(R)-3-hydroxybutyrate], poly(ethylene glycol), and poly(propylene glycol). Biomaterials 2007, 28(28):4113-4123.
22. Loh X.J., Goh S.H., Li J. New biodegradable thermogelling copolymers having very low gelation concentrations. Biomacromolecules 2007, 8(2):585-593.
23. Loh X.J., Li J. Biodegradable thermosensitive copolymer hydrogels for drug delivery. Expert Opinion on Therapeutic Patents 2007, 17(8):965-977.
24. Loh X.J., Tan Y.X., Li Z.Y., Teo L.S., Goh S.H., Li J. Biodegradable thermogelling poly(ester urethane)s consisting of poly(lactic acid) - thermodynamics of micellization and hydrolytic degradation. Biomaterials 2008, 29(14):2164-2172.
25. Bezwada R.S., Jamiolkowski D.D., Lee I.Y., Agarwal V., Persivale J., Trenkabenthin S., Erneta M., Suryadevara J., Yang A., Liu S. Monocryl(r) suture, a new ultra-pliable absorbable monofilament suture. Biomaterials 1995, 16(15):1141-1148.
26. Pitt C.G., Gratzl M.M., Kimmel G.L., Surles J., Schindler A. Aliphatic polyesters. 2. The degradation of poly(dl-lactide), poly(epsilon-caprolactone), and their copolymers invivo. Biomaterials 1981, 2(4):215-220.
27. Loh X.J., Wu Y.L., Seow W.T.J., Norimzan M.N.I., Zhang Z.X., Xu F., Kang E.T., Neoh K.G., Li J. Micellization and phase transition behavior of thermosensitive poly(N-isopropylacrylamide)-poly(epsilon-caprolactone)-poly (N-isopropylacrylamide) triblock copolymers. Polymer 2008, 49(23):5084-5094.
28. Chellat F., Tabrizian M., Dumitriu S., Chornet E., Magny P., Rivard C.H., Yahia L. In vitro and in vivo biocompatibility of chitosan-xanthan polyionic complex. Journal of Biomedical Materials Research 2000, 51(1):107-116.
29. Cui W.G., Li X.H., Zhu X.L., Yu G., Zhou S.B., Weng J. Investigation of drug release and matrix degradation of electrospun poly(dl-lactide) fibers with paracetanol inoculation. Biomacromolecules 2006, 7(5):1623-1629.
30. Tungprapa S., Jangchud I., Supaphol P. Release characteristics of four model drugs from drug-loaded electrospun cellulose acetate fiber mats. Polymer 2007, 48(17):5030-5041.
31. Gandhi M., Srikar R., Yarin A.L., Megaridis C.M., Gemeinhart R.A. Mechanistic examination of protein release from polymer nanofibers. Molecular Pharmaceutics 2009, 6(2):641-647.
32. Koutsopoulos S., Unswortha L.D., Nagaia Y., Zhang S.G. Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold. Proceedings of the National Academy of Sciences of the United States of America 2009, 106(12):4623-4628.
33. Zeng R., Tu M., Liu H.W., Zhao J.H., Zha Z.G., Zhou C.R. Preparation, structure and drug release behaviour of chitosan-based nanofibres. IET Nanobiotechnology 2009, 3(1):8-13.
34. Zhang Y.Z., Wang X., Feng Y., Li J., Lim C.T., Ramakrishna S. Coaxial electrospinning of (fluorescein isothiocyanate-conjugated bovine serum albumin)-encapsulated poly(epsilon-caprolactone) nanofibers for sustained release. Biomacromolecules 2006, 7(4):1049-1057.
35. Dror Y., Ziv T., Makarov V., Wolf H., Admon A., Zussman E. Nanofibers made of globular proteins. Biomacromolecules 2008, 9(10):2749-2754.
36. Kowalczyk T., Nowicka A., Elbaum D., Kowalewski T.A. Electrospinning of bovine serum albumin. Optimization and the use for production of biosensors. Biomacromolecules 2008, 9(7):2087-2090.
37. Lu Y., Jiang H.L., Tu K.H., Wang L.Q. Mild immobilization of diverse macromolecular bioactive agents onto multifunctional fibrous membranes prepared by coaxial electrospinning. Acta Biomaterialia 2009, 5(5):1562-1574.
38. Park K.E., Kang H.K., Lee S.J., Min B.M., Park W.H. Biomimetic nanofibrous scaffolds: preparation and characterization of PGA/chitin blend nanofibers. Biomacromolecules 2006, 7(2):635-643.
39. Qi H.X., Hu P., Xu J., Wang A.J. Encapsulation of drug reservoirs in fibers by emulsion electrospinning: morphology characterization and preliminary release assessment. Biomacromolecules 2006, 7(8):2327-2330.
40. Zhang C.X., Yuan X.Y., Wu L.L., Sheng J. Drug-loaded ultrafine poly(vinyl alcohol) fibre mats prepared by electrospinning. E-Polymers 2005, 072.
41. Yang Y., Li X., Cui W., Zhou S., Tan R., Wang C. Structural stability and release profiles of proteins from core-shell poly (dl-lactide) ultrafine fibers prepared by emulsion electrospinning. Journal of Biomedical Materials Research Part A 2008, 86A(2):374-385.
42. Wan J.P., Yang Y.Y., Chung T.S., Tan D., Ng S., Heller J. POE-PEG-POE triblock copolymeric microspheres containing protein - II. Polymer erosion and protein release mechanism. Journal of Controlled Release 2001, 75(1-2):129-141.
43. Yang Y.Y., Wan J.P., Chung T.S., Pallathadka P.K., Ng S., Heller J. POE-PEG-POE triblock copolymeric microspheres containing protein - I. Preparation and characterization. Journal of Controlled Release 2001, 75(1-2):115-128.
44. Emami J., Hamishehkar H., Najafabadi A.R., Gilani K., Minaiyan M., Mahdavi H., Nokhodchi A. A novel approach to prepare insulin-loaded poly (lactic-co-glycolic acid) microcapsules and the protein stability study. Journal of Pharmaceutical Sciences 2009, 98(5):1712-1731.
45. Kim T.G., Lee D.S., Park T.G. Controlled protein release from electrospun biodegradable fiber mesh composed of poly(epsilon-caprolactone) and poly(ethylene oxide). International Journal of Pharmaceutics 2007, 338(1-2):276-283.
46. Takafuji H., Suzuki T., Okubo Y., Fujimura K., Bessho K. Regeneration of articular cartilage defects in the temporomandibular joint of rabbits by fibroblast growth factor-2: a pilot study. International Journal of Oral and Maxillofacial Surgery 2007, 36(10):934-937.
47. Gupta P.S.P., Ravindranatha B.M., Nandi S., Sarma P.V. In vitro maturation of buffalo oocytes with epidermal growth factor and fibroblast growth factor. Indian Journal of Animal Sciences 2002, 72(1):23-26.
48. Deister C., Schmidt C.E. Optimizing neurotrophic factor combinations for neurite outgrowth. Journal of Neural Engineering 2006, 3(2):172-179.
49. Jeong B., Bae Y.H., Kim S.W. Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers. Journal of Controlled Release 2000, 63(1-2):155-163.
50. Chu X.H., Shi X.L., Feng Z.Q., Gu Z.Z., Ding Y.T. Chitosan nanofiber scaffold enhances hepatocyte adhesion and function. Biotechnology Letters 2009, 31(3):347-352.
51. Chua K.N., Chai C., Lee P.C., Tang Y.N., Ramakrishna S., Leong K.W., Mao H.Q. Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells. Biomaterials 2006, 27(36):6043-6051.
52. Ito Y., Hasuda H., Kamitakahara M., Ohtsuki C., Tanihara M., Kang I.K., Kwon O.H. A composite of hydroxyapatite with electrospun biodegradable nanofibers as a tissue engineering material. Journal of Bioscience and Bioengineering 2005, 100(1):43-49.
53. Woo K.M., Chen V.J., Ma P.X. Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment. Journal of Biomedical Materials Research Part A 2003, 67A(2):531-537.
54. Schoonover J.R., Thompson D.G., Osborn J.C., Orler E.B., Wrobleski D.A., Marsh A.L., Wang H.C., Palmer R.A. Infrared linear dichroism study of a hydrolytically degraded poly(ester urethane). Polymer Degradation and Stability 2001, 74(1):87-96.
55. Loh X.J., Tan K.K., Li X., Li J. The in vitro hydrolysis of poly(ester urethane)s consisting of poly[(R)-3-hydroxybutyrate] and poly(ethylene glycol). Biomaterials 2006, 27(9):1841-1850.