Importance of polar solvation for cross-reactivity of antibody and its variants with steroids

Journal of Physical Chemistry B

Volumn 115, Issue 23, 2011, Pages 7661-7669

  Kar, Parimal ^a,b   Lipowsky, Reinhard ^a   Knecht, Volker ^a  

^a MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; COMPLEXATION; FREE ENERGY; LIPIDS; MODEL STRUCTURES; MOLECULAR BIOLOGY; MOLECULAR RECOGNITION; SOLVATION; VAN DER WAALS FORCES;

ANTI-PROGESTERONE; BINDING FREE ENERGY; BINDING MECHANISMS; CROSS-REACTIVITY; DIELS-ALDERASE; DOUBLE MUTANTS; DRUG DESIGN; EXPERIMENTAL DATA; POLAR GROUPS; QUANTITATIVE AGREEMENT; SINGLE MUTANT; SOLVATION EFFECT; STRUCTURAL INSPECTIONS; STRUCTURAL MODELS; SURFACE AREA; VAN DER WAALS INTERACTIONS;

BINDING ENERGY;

EID: 79958833423     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp201538t     Document Type: Article

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