Analysis of the binding energies of testosterone, 5α-dihydrotestosterone, androstenedione and dehydroepiandrosterone sulfate with an antitestosterone antibody

Proteins: Structure, Function and Genetics

Volumn 50, Issue 1, 2003, Pages 135-143

  Nordman, Nana ^a   Valjakka, Jarkko ^a   Peräkylä, Michael ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Antibody Fab fragment; Free energy calculation; Molecular dynamics; Mutagenesis; Steroid hormone

Indexed keywords

ANDROSTANOLONE; ANDROSTENEDIONE; ESTRADIOL ANTIBODY; HORMONE ANTIBODY; LIGAND; PRASTERONE SULFATE; PROGESTERONE ANTIBODY; STEROID HORMONE; TESTOSTERONE; TESTOSTERONE ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; ENERGY; HORMONE BINDING; HORMONE STRUCTURE; HYDROGEN BOND; IMMUNOASSAY; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MUTAGENESIS; PRIORITY JOURNAL; SIMULATION;

ANDROGENS; ANDROSTENEDIONE; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; BINDING SITES, ANTIBODY; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DEHYDROEPIANDROSTERONE SULFATE; DIHYDROTESTOSTERONE; IMMUNOGLOBULIN FAB FRAGMENTS; MACROMOLECULAR SUBSTANCES; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; TESTOSTERONE;

EID: 0037235649     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10267     Document Type: Article

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