A 2B adenosine receptors inhibit superoxide production from mitochondrial complex i in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxin

British Journal of Pharmacology

Volumn 163, Issue 5, 2011, Pages 995-1006

  Yang, Xiulan ^a   Xin, Wenkuan ^a   Yang, Xi Ming ^a   Kuno, Atsushi ^a   Rich, Thomas C ^a   Cohen, Michael V ^a   Downey, James M ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

adenosine A 2B receptor; cardiomyocytes; ERK phosphorylation; HEK A 2B cells; reperfusion injury; superoxide generation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2B RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FLUORESCENT DYE; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ION CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; NITRIC OXIDE SYNTHASE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; SUPEROXIDE; WORTMANNIN; NITRIC OXIDE;

ARTICLE; CATION TRANSPORT; CELL ISOLATION; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; ISCHEMIC PRECONDITIONING; MITOCHONDRION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RABBIT; RECEPTOR UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL MEMBRANE POTENTIAL; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; HEART MITOCHONDRION; MALE; METABOLISM; PHYSIOLOGY;

ANIMALS; BLOTTING, WESTERN; CYCLIC AMP; ELECTRON TRANSPORT COMPLEX I; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HEK293 CELLS; HUMANS; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; NITRIC OXIDE; PATCH-CLAMP TECHNIQUES; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3-KINASES; RABBITS; RECEPTOR, ADENOSINE A2B; SUPEROXIDES; TRANSFECTION;

EID: 79958807712     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01288.x     Document Type: Article

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