AMP579 is revealed to be a potent A2b-adenosine receptor agonist in human 293 cells and rabbit hearts

Basic Research in Cardiology

Volumn 105, Issue 1, 2010, Pages 129-137

  Liu, Yanping ^a   Yang, Xiulan ^a   Yang, Xi Ming ^a   Walker, Sheree ^a   Förster, Karina ^b   Cohen, Michael V ^a   Krieg, Thomas ^b   Downey, James M ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

A2b receptor; Adenosine; AMP579; Cardioprotection; Myocardial infarction

Indexed keywords

4 [7 [[1 [(3 CHLORO 2 THIENYL)METHYL]PROPYL]AMINO] 3H IMIDAZO[4,5 B]PYRIDIN 3 YL] N ETHYL 2,3 DIHYDROXYCYCLOPENTANECARBOXAMIDE; ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; N (4 CYANOPHENYL) 2 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)PHENOXY]ACETAMIDE; PSB 1115; UNCLASSIFIED DRUG; 4 (7 ((2 3 CHLORO 2 THIENYL) 1 METHYL PROPYLAMINO) 3H IMIDAZO(4,5 B)PYRIDYL 3 YL)CYCLOPENTANE CARBOXAMIDE; 4-(7-((2-3-CHLORO-2-THIENYL)-1-METHYL-PROPYLAMINO)-3H-IMIDAZO(4,5-B)PYRIDYL-3-YL)CYCLOPENTANE CARBOXAMIDE; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG POTENCY; DRUG SPECIFICITY; ENZYME PHOSPHORYLATION; HEART INFARCTION; HEART INFARCTION SIZE; HEART PROTECTION; HUMAN; HUMAN CELL; NONHUMAN; REPERFUSION INJURY; ANIMAL; CELL LINE; DRUG POTENTIATION; FEMALE; HEART MUSCLE; HEMODYNAMICS; IN VITRO STUDY; MALE; PATHOLOGY; PATHOPHYSIOLOGY; RABBIT;

ANIMALS; CELL LINE; FEMALE; HEMODYNAMICS; HUMANS; IMIDAZOLES; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PYRIDINES; RABBITS; RECEPTOR, ADENOSINE A2B;

EID: 72449154109     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-009-0056-9     Document Type: Article

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